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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

    • Medicinal Plant Research in Africa

      • 2nd Edition
      • April 16, 2025
      • Victor Kuete
      • English
      • Hardback
        9 7 8 0 4 4 3 3 0 1 7 0 4
      • eBook
        9 7 8 0 4 4 3 3 0 1 7 1 1
      Medicinal Plant Research in Africa, second edition is an updated and complete reference on the pharmacology of most relevant African species and their phytochemical properties. Although pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes, however there was no global standard book on the nature and specificity of chemicals isolated in African medicinal plants. This book has set the standard when it first published in 2013 and now is updated with novel phytochemicals belonging to diverse classes of terpenoids, phenolics, and alkaloids. The first chapter cover monoterpenes and related phytochemicals and is followed by sesquiterpenes on chapter two. Chapter tri reviews diterpenoids and chapter four provides an overview of triterpenes and steroids. Essential oils, simple phenols, phenolic acids and related esters come next in chapters five and six, respectively. The following chapters cover coumarins, flavonoids, quinones, xanthones, lignans and stilbenes. Tannins, alkaloids, and ceramides. Chapters 15 to 20 focus on specific health conditions starting with antibiotic infection, antimalarial and other antiprotozoal diseases, cytotoxic and anticancer activity, anti-inflammatory and analgesic action, antidiabetic botanicals and the applications of African plant phytochemicals on reproductive, cardiovascular, and central nervous systems conditions. The final chapter covers the market and industry updates since the first edition published. "Medicinal Plant Research in Africa, 2 Ed." provides a complete overview of the main phytochemical principles present in the African flora and their pharmaceutical use. Pharmaceutical scientists, Ethnopharmacists, botanists, and medicinal chemists will benefit from the content organization and the inclusion of the most recent methods for structural identification of phytochemicals, pharmacological techniques, and data interpretation.
    • Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

      • 2nd Edition
      • February 18, 2025
      • Mahendra Rai
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 0 4 4 2
      • eBook
        9 7 8 0 4 4 3 2 9 0 4 5 9
      Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the most relevant studies for fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses, and fungi using natural products. This new edition expands the coverage of uses of traditional medicinal plants to against MDR, includes new chapters on the potential of plant-derived bioactive compounds for reversal of multidrug resistances, covers the use of flavonoids to combat microbes and cancer, and the use of nanoparticles as drug delivery vehicle.The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery.
    • Curcumin Bioavailability and Sustainability as Therapeutic Agent

      • 1st Edition
      • August 20, 2025
      • Mahmood Ahmed + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 9 1 9 6 8
      • eBook
        9 7 8 0 4 4 3 2 9 1 9 7 5
      Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin is a comprehensive reference on techniques to enhance the bioavailability of curcumin, while also covering sustainability aspects across its production cycle. This book focuses on the information needs of pharmaceutical scientists aiming at developing drug delivery systems and formulations that can maximize the therapeutic impact of curcumin drugs. After an introduction to curcumin therapeutic properties, the authors delve into the bioavailability challenges confronted by curcumin, discussing influencing factors, pharmacokinetic pathways, and formulations to augment its bioaccessibility. Chapter 3 explores innovative formulation paradigms, encompassing nanoparticle-based delivery systems and lipidic matrices, tailored to overcome solubility limitations and increase absorptive efficacy. Chapter 4 covers delivery systems, encompassing prodrug strategies, encapsulation modalities, and nanocarrier technologies. Chapter 5 investigates sustainable sourcing and production, raising awareness to ethical cultivation practices, eco-friendly extraction methodologies, and proficient waste management techniques within curcumin production processes. In Chapter 6 discusses balancing bioavailability augmentation with sustainability principles including case studies. Chapter 7 navigates the domain of pharmacokinetic studies and clinical trials, providing an overview of bioaccessibility and bioavailable formulations. Chapter 8 explores safety profiles, regulatory requirements, and quality benchmarks, encompassing product labeling and claims concerning curcumin's bioavailability and sustainability. Chapter 9 casts a future view contemplating nascent technologies for bioavailability and sustainability optimization. The final chapter concludes the book with the author's observations on its central themes. Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin provides practical strategies to be explored by pharmaceutical scientists in increasing bioavailability of curcumin formulations. Research physicians and nutritionists may also benefit from the evidence-based information on curcumin's therapeutic activities provided across the book.
    • Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology

      • 1st Edition
      • June 18, 2025
      • Muhammad Ishfaq
      • English
      • Paperback
        9 7 8 0 4 4 3 3 3 0 2 4 7
      • eBook
        9 7 8 0 4 4 3 3 3 0 2 5 4
      Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology is a comprehensive resource that offers an advanced overview of computational techniques employed in drug discovery, design, and toxicity prediction. The book discusses various topics, including molecular modeling, virtual screening, machine learning, and network pharmacology. It serves as an essential guide for researchers, practitioners, and students in pharmacology, toxicology, medicinal chemistry, bioinformatics, and systems biology fields, showcasing practical applications and future perspectives on new technologies. In addition to covering computational approaches, the book provides real-world examples of drug discovery, candidate optimization, and safety assessment.Other sections explore computer applications in pharmacology and toxicology and discusses the importance of these methods in advancing medicinal research.
    • Emerging Therapeutic Targets and Drug Delivery Approaches in IBD

      • 1st Edition
      • Volume 101
      • November 12, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 3 5 8 5
      • eBook
        9 7 8 0 4 4 3 3 1 3 5 9 2
      Emerging Therapeutic Targets and Drug Delivery Approaches in IBD, Volume 101 in this ongoing series, highlights new advances, with this volume presenting interesting chapters on timely topics, including Fibrosis in IBD – AXL as a Promising Therapeutic Target, Developing a pathway to test anti-fibrotic drugs in Crohn’s disease, Emerging therapeutics for the management of intestinal fibrosis and strictures, GCPII for IBD, Fistulas/stem cell products for IBD/Crohn’s, The landscape of new therapeutic opportunities for IBD, TL1A : A Model For The Use Of Precision Medicine For The Treatment of Crohn’s Disease and Ulcerative Colitis, Dectin-1 as a therapeutic target for IBD, and more.Additional sections cover BRD4 as an Emerging Epigenetic Therapeutic Target for Inflammatory Bowel Diseases, Scripps - S1P, The potential of targeting TREM-1 in Inflammatory Bowel Disease, and Microbiome therapies.
    • Brody's Human Pharmacology

      • 7th Edition
      • March 22, 2024
      • Lynn Wecker + 1 more
      • English
      Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.
    • The Discovery of New Medicines in Academia

      • 1st Edition
      • Volume 100
      • July 18, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 3 2 4 5
      • eBook
        9 7 8 0 4 4 3 2 9 3 2 5 2
      The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/developmen... of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.
    • Pharmacological Advances in Central Nervous System Stimulants

      • 1st Edition
      • Volume 99
      • March 9, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 9 3 3 7
      • eBook
        9 7 8 0 4 4 3 2 1 9 3 4 4
      Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Relate... Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more.
    • Rang y Dale. Farmacología

      • 10th Edition
      • May 15, 2024
      • James M. Ritter + 4 more
      • Spanish
      • Paperback
        9 7 8 8 4 1 3 8 2 6 9 0 5
      • eBook
        9 7 8 8 4 1 3 8 2 7 5 7 5
      Nueva edición del texto clásico en Farmacología y de referencia para los estudiantes de Medicina en el que se aborda de forma exhaustiva, pero clara y organizada el mecanismo de acción de los fármacos más comúnmente usados, tanto a nivel molecular o celular, como de los mecanismos fisiológicos sobre los que actúan.Se ha mantenido la organización general del libro, dividido en 6 grandes secciones en las que se ofrece una descripción de los efectos y usos de los diferentes fármacos junto con su acción sobre las vías de señalización subyacentes a todos los procesos fisiológicos que ocurren en el ser humano. En cuanto a las novedades, si bien todos los capítulos se han actualizado, algunos de ellos han sufrido grandes cambios. Así cabe destacar: Cap 5 (se han incluido un mayor número de fármacos RNA), Cap 24 (recientes avances en la medición de la presión de oxígeno), Cap 40 (se ha puesto el foco en el Alzheimer y la demencia vascular y la asociada a los cuerpos de Levy), Cap 43 (nueva sección destinada al tratamiento del dolor crónico), Cap 51 (nuevos diagramas que ilustran los lugares de acción de los antibióticos a nivel de los ribosomas), Cap 53 (información sobre el modo de replicación de los retrovirales y una sección específica de Covid19) y Cap 57 ( gran y amplia cobertura de los nuevos fármacos anticancerosos). Se ha introducido dos nuevos capítulos. Uno de ellos dedicado a la Farmacología ocular y otro dedicado al tratamiento farmacológico de la migraña en el que se incluyen los nuevos antagonistas de CGRP y su uso profiláctico para la migraña. La nueva edición incluye acceso al e-book en español en el que se incluye contenido adicional (casos clínicos y preguntas de autoevaluación) también en español.
    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 63
      • October 4, 2024
      • English
      Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.