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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

    • Cancer Drug Design and Discovery

      • 2nd Edition
      • September 30, 2013
      • Stephen Neidle
      • English
      • Hardback
        9 7 8 0 1 2 3 9 6 5 2 1 9
      • eBook
        9 7 8 0 1 2 3 9 7 2 2 8 6
      Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted agents and more. This book includes several sections on the basic and applied science of cancer drug discovery and features those drugs that are now approved for human use and are in the marketplace, as well as those that are still under development. By highlighting some of the general principles involved in taking molecules through basic science to clinical development, this book offers a complete and authoritative reference on the design and discovery of anticancer drugs for translational scientists and clinicians involved in cancer research.
    • Computer-Aided Applications in Pharmaceutical Technology

      • 1st Edition
      • April 10, 2013
      • Jelena Duris
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 2 7 5
      • eBook
        9 7 8 1 9 0 8 8 1 8 3 2 4
      Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-Aided Applications in Pharmaceutical Technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology.
    • Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases

      • 1st Edition
      • December 16, 2013
      • Christophe Wiart
      • English
      • Hardback
        9 7 8 0 1 2 3 9 8 3 7 3 2
      • eBook
        9 7 8 0 1 2 3 9 8 3 8 3 1
      Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development.
    • Inhaler Devices

      • 1st Edition
      • April 23, 2013
      • Polina Prokopovich
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 6 1 2 1
      • Hardback
        9 7 8 0 8 5 7 0 9 4 9 6 4
      • eBook
        9 7 8 0 8 5 7 0 9 8 6 9 6
      Given their direct impact on the health and quality of life for millions, inhalers represent a major turning point in the history of modern medicine. Inhaler devices: Fundamentals, design and drug delivery provides readers with an introduction to the fundamentals of inhaler technology, with a comprehensive discussion of the history of inhalers as well as a discussion on current research and development.Part one discusses the fundamentals and development of inhaler devices as well as drug formulations for inhalers. The treatment of asthma is also discussed. Part two reviews recent developments in drug formulation and nanotechnology for inhaler devices, emerging inhaler technology and possible future trends.Inhaler devices: Fundamentals, design and drug delivery is an essential design guide for good industrial practice, and will be an invaluable resource for those researching and treating conditions such as asthma; and those developing and manufacturing inhalation devices.
    • Histone Deacetylase Inhibitors as Cancer Therapeutics

      • 1st Edition
      • Volume 116
      • November 1, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 3 8 7 3
      • eBook
        9 7 8 0 1 2 3 9 4 6 0 8 9
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics."
    • Profiles of Drug Substances, Excipients and Related Methodology

      • 1st Edition
      • Volume 37
      • March 30, 2012
      • Harry G. Brittain
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 2 2 0 0
      • eBook
        9 7 8 0 1 2 3 9 7 7 5 6 4
      Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.
    • Current Concepts in Drug Metabolism and Toxicology

      • 1st Edition
      • Volume 63
      • June 12, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 8 3 3 9 8
      • Paperback
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      • eBook
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      This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 51
      • May 9, 2012
      • English
      • Paperback
        9 7 8 0 4 4 4 6 0 2 2 6 8
      • Hardback
        9 7 8 0 1 2 3 9 6 4 9 3 9
      • eBook
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      Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.
    • Workbook for Pharmacology for Pharmacy Technicians

      • 2nd Edition
      • December 7, 2012
      • Kathy Moscou + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 0 8 4 9 8 7
      • eBook
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      Specially designed to parallel the material in Pharmacology for Pharmacy Technicians, 2nd Edition, this helpful workbook provides in-depth study and review of the ASHP content requirements for pharmacology and anatomy and physiology. Its user-friendly format and engaging learning exercises help you understand both basic and advanced pharmacologic concepts. Practical activities allow you to apply your knowledge to real-world scenarios.
    • Contract Research and Manufacturing Services (CRAMS) in India

      • 1st Edition
      • October 31, 2012
      • Milind Antani + 1 more
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 1 9 0
      • eBook
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      The field of contract research and manufacturing broadly encompasses those services in the pharmaceutical and biotechnology sectors that require extensive research and development and large-scale manufacturing facilities. The field has great potential for growth in the Indian outsourcing industry, which is world-renowned for its provision of cheap and highly-skilled services. Contract research and manufacturing services (CRAMS) in India provides a detailed account of the current scenario in India and the advantages that the Indian outsourcing industry can offer in the field of CRAMS. Following an overview of the services and their emergence in India, chapters in the book begin by discussing the legal and regulatory scenario and major concerns and issues. In the latter part of the book, topics covered include service agreements, dispute resolution and contract negotiations, followed by a discussion of the outlook for CRAMS in India and some concluding remarks. Several appendices are included, offering a list of major players in the field and various forms for use in licence applications.