Skip to main content
Elsevier
View Cart

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Theoretical Biochemistry

      • 1st Edition
      • Volume 9
      • February 19, 2001
      • Leif A. Eriksson
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 2 9 2 6
      • eBook
        9 7 8 0 0 8 0 5 4 2 7 0 6
      Theoretical chemistry has been an area of tremendous expansion and development over the past decade; from an approach where we were able to treat only a few atoms quantum mechanically or make fairly crude molecular dynamics simulations, into a discipline with an accuracy and predictive power that has rendered it an essential complementary tool to experiment in basically all areas of science. This volume gives a flavour of the types of problems in biochemistry that theoretical calculations can solve at present, and illustrates the tremendous predictive power these approaches possess.A wide range of computational approaches, from classical MD and Monte Carlo methods, via semi-empirical and DFT approaches on isolated model systems, to Car-Parinello QM-MD and novel hybrid QM/MM studies are covered. The systems investigated also cover a broad range; from membrane-bound proteins to various types of enzymatic reactions as well as inhibitor studies, cofactor properties, solvent effects, transcription and radiation damage to DNA.

    • Hypertheromphilic Enzymes, Part A

      • 1st Edition
      • Volume 330
      • February 8, 2001
      • English
      • eBook
        9 7 8 0 0 8 0 4 9 6 8 5 6
      The critically acclaimed laboratory standard for more than forty years, Methods in Enzymologyis one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 31 and 334) cover all current knowledge concerning hyperthermophilic enzymes. Major topics in this volume include enzyme discovery, saccharolytic enzymes, and proteolytic enzymes.

    • Regulators and Effectors of Small GTPases, Part E: GTPases Involved in Vesicular Traffic

      • 1st Edition
      • Volume 329
      • January 25, 2001
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 1 6 0 8
      • eBook
        9 7 8 0 0 8 0 4 9 6 8 4 9
      Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport.This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.

    • Agriculture and Food Production

      • 1st Edition
      • Volume 1
      • January 24, 2001
      • English
      • Paperback
        9 7 8 0 4 4 4 5 3 9 9 4 6
      • eBook
        9 7 8 0 0 8 0 5 2 7 4 3 7
      Presenting a stimulating synthesis of rapidly growing research interests and publications by scholars in the field of applied mycology and biotechnology.The surge of research and development activity in applied mycology and fungal biotechnology relates to the need and utility of fungi in many contexts. These contexts are wide in scope, and include agriculture, animal and plant health, biotransformation of organic or inorganic matter, food safety, composition of nutrients and micronutrients, and human and animal infectious disease.Containing a balanced treatment of principles, biotechnological manipulations and applications of major groups of fungi in agriculture and food, this book will serve as a practical resource for mycologists, microbiologists, biotechnologists, bioengineers, scientists from agri-food industry, biochemists, botanists and agriculturists.

    • Genomic Regulatory Systems

      • 1st Edition
      • January 24, 2001
      • Eric H. Davidson
      • English
      • eBook
        9 7 8 0 0 8 0 5 2 5 5 9 4
      The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest.The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist.

    • The Oncobiology of the Prostate

      • 1st Edition
      • Volume 3
      • December 20, 2000
      • D.P. Wood + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 1 6 6 6
      • eBook
        9 7 8 0 0 8 0 5 3 7 9 9 3
      Prostate cancer (PCa) is the most common newly diagnosed cancer among men in the United States today. With the advent of the prostate-specific antigen (PSA) test, the number of newly diagnosed cases has increased tremendously. The rates of PCa have increased so dramatically over the last decade that the age-adjusted incidence rate of PCa is no greater than that for any other cancer among men in the United States. Although PCa rates have risen steadily since 1973, there has been a dramatic acceleration in the late 1980s which has been associated with the introduction and use of PSA for screening and early detection. There is now some evidence that the rates may be levelling off and even decreasing in some areas. After lung cancer, PCa is the leading cause of death due to cancer in men in the United States. Although PCa can occur in younger men, it is essentially a cancer of elderly men. The highest rates of PCa in the world occur among African-American men in the United States. African-Americans have higher rates than Caucasians at all age levels in the United States, and adjusting for social-economic status does not appear to account for this difference to any appreciable extent. There is no clear reason why PCa rates are so much greater among African-Americans compared with Caucasians in the United States. The reported rates in Africans are substantially lower than those of an African-American, suggesting that environmental factors have an influence on PCa. In spite of this substantial impact on our society. PCa remains a relatively understudied disease, with an essentially unknown etiology. The reviews contained in this book are by no means exhaustive. We have, however, attempted to provide information regarding the pathology of prostate cancer, the status of diagnostic and prognostic markers, as well as a discussion of our understanding of the molecular basis for the disease. The biology of prostate cancer is covered with a discussion on the role of apoptosis in prostate cancer and the suggestion of it being the target for new therapeutic development, as well as the role played by integrins and angiogenesis. The status of current therapies, both hormonal and chemotherapy, are also discussed. This volume should provide a useful background for individuals wishing to commence an in-depth understanding of prostate cancer.

    • Cofactor Biosynthesis: A Mechanistic Perspective

      • 1st Edition
      • Volume 61
      • December 18, 2000
      • Gerald Litwack
      • English
      • Hardback
        9 7 8 0 1 2 7 0 9 8 6 1 6
      • Paperback
        9 7 8 0 1 2 3 9 1 0 7 2 1
      • eBook
        9 7 8 0 0 8 0 5 4 4 5 3 3
      The longest running serial published by Academic Press continues its well-respected run with Volume 61, a special volume in which a guest editor has come on board and has assembled some well-known contributors who are international authorities in the field. Together they tackle some of the latest topics in the field such as riboflavin and folate biosynthesis, biotin and lipoic acid biosynthesis, nicotinamide adenine dinucleotide biosynthesis, biosynthesis of vitamin B6 and structurally related derivatives, pantothenic acid and coenzyme A biosynthesis, mechanistic biosynthesis of protein-derived redox cofactors, ascorbic acid biosynthesis, biosynthesis of menaquinone and ubiquinone - Vitamin B12 biosynthesis, biosynthesis of the methanogenic cofactors, and thiamin biosynthesis.

    • Epilepsy and Sleep

      • 1st Edition
      • December 18, 2000
      • Dudley S. Dinner + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 9 2 1 1 6
      • Hardback
        9 7 8 0 1 2 2 1 6 7 7 0 6
      • eBook
        9 7 8 0 0 8 0 4 9 1 2 8 8
      It is well recognized that there is an intimate and reciprocal interaction between epilepsy and sleep. The book, Epilepsy and Sleep is a ground-breaking, comprehensive source for exploring this correlation and is especially timely because of the considerable growth in the understanding of the physiology underlying both sleep and epilepsy. An insightful reference, it presents many of the complex physiologic mechanisms underlying epilepsy--sleep interaction and highlights sleeping disorder symptoms that may be related to epilepsy. The annual cost of treating epilepsy in the United States is an estimated $12.5 billion, according to a report issued January 2000 by The Epilepsy Foundation. The Foundation also reports that more than 180,000 Americans develop epilepsy each year. However, thousands more cases may be misdiagnosed as sleeping disorders, causing these figures to jump significantly. This correlation and diagnosis can help determine the correct type of medication to administer to regulate the symptoms, in turn saving hundreds of hours of lost time at work and millions of dollars.

    • Cell Lineage and Embryo Patterning

      • 1st Edition
      • Volume 203
      • December 13, 2000
      • English
      • eBook
        9 7 8 0 0 8 0 4 8 9 1 5 5
      International Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus.

    • Cancer Metastasis: Experimental Approaches

      • 1st Edition
      • Volume 29
      • December 11, 2000
      • D. Rusciano + 1 more
      • D.R. Welch
      • English
      • Hardback
        9 7 8 0 4 4 4 8 2 3 7 2 4
      • Paperback
        9 7 8 0 4 4 4 8 2 3 5 8 8
      • eBook
        9 7 8 0 0 8 0 9 3 3 3 7 5
      The book describes most of the methods that are currently used in metastasis research. Both in vivo and in vitro protocols are illustrated, so that the metastatic process can be either analysed as a whole, or single events addressed separately. Each method is described in the frame of the metastatic process, therefore its significance and its limitations in the context of metastasis are always taken into account. Whenever possible, several alternative procedures are reported per each experimental issue, so that the researcher can choose the one that better suits her/his needs and possibilities.During the past 30 years a big effort has been made to elucidate the molecular mechanisms of cancer metastatis, the leading cause of death for cancer patients. A considerable number of assays have been set up, that can be used to address specific questions concerning the single metastatic steps, or can be applied to develop and test drugs specifically interfering with selected events during the metastatic spread. This book contains an exhaustive description of most of the methods and their rationale, that are currently used in metastatic research, both to analyse metastasis in its entirety (in vivo models), or to dissect the single steps of the metastatic process (in vitro assays).

Related subjects

Biochemistry biophysics

Biotechnology

Endocrinology

Life sciences general

Molecular biology cellular biology and genetics

Physiology