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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Principles and Practice of Clinical Research

      • 2nd Edition
      • April 24, 2007
      • John I. Gallin + 1 more
      • English
      • eBook
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      The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.

    • Mechanosensitive Ion Channels, Part B

      • 1st Edition
      • Volume 59
      • April 19, 2007
      • English
      • Hardback
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      • eBook
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      Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include ENaC Proteins in Vascular Smooth Muscle Mechanotransduction; Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids; MechanoTRPs and TRPA1; TRPC; The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism. Lessons From Polycystin-2 (TRPP2); Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels; Hair Cell Mechanotransduction: The Dynamic Interplay between Structure and Function; Pharmacology of Hair Cell MS Channels; Hair Cell Mechanotransduction; Models of Hair Cell Mechanotrasduction; Touch; Mechanosensitive Ion Channels in Dystrophic Muscle; Mechanotransduction in Endothelial Cells;MS Channels in Tumor Cell Migration; Mechanosensitive Channels in Regulating Smooth Muscle Contraction in the GI; Mechanosensitive Ion Channels in Blood-Pressure-Sensi... Baroreceptor Neurons.

    • International Review of Cytology

      • 1st Edition
      • Volume 259
      • April 13, 2007
      • Kwang W. Jeon
      • English
      • Hardback
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      • Paperback
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      • eBook
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      International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume features articles on Molecular mechanism of liver development and regeneration; Molecular basis of vertebrate endoderm development; YidC as an essential and multifunctional component in membrane protein assembly; Mitotic spindle dynamics in Drosophila; and Neurogenesis in the Fish Retina.

    • Mechanosensitive Ion Channels, Part A

      • 1st Edition
      • Volume 58
      • April 10, 2007
      • English
      • Hardback
        9 7 8 0 1 2 1 5 3 3 5 8 8
      • Paperback
        9 7 8 0 3 2 3 2 8 4 2 2 6
      • eBook
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      Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include The Mechanical Properties of Bilayers; Molecular Dynamic Modeling of MS Channels; Structures of the Prokaryotic Mechanosensitive; Channels MscL and MscS; 3.5 Billion Years of Mechanosensory Transduction: Structure and Function of Mechanosensitive Channels in Prokaryotes; Activation of Mechanosensitive Ion Channels by Forces Transmitted through Integrins and the Cytoskeleton; Thermodynamics of Mechanosensitivity; Flexoelectricity and Mechanotransduction; Lipid Effects on Mechanosensitive Channels; Functional Interactions of the Extracellular Matrix with Mechanosensitive Channels; MSCL: The Bacterial Mechanosensitive Channel of Large Conductance; The Bacterial Mechanosensitive Channel MscS: Emerging Principles of Gating and Modulation; Structure function relations of MscS; The MscS Cytoplasmic Domain and its Conformational Changes upon the Channel Gating; Microbial TRP Channels and Their Mechanosensitivity; MSCS-Like Proteins in Plants; Delivering Force and Amplifying Signals in Plant Mechanosensing; MS Channels in Tip Growing Systems.

    • Mitochondria

      • 2nd Edition
      • Volume 80
      • April 10, 2007
      • Liza A. Pon + 1 more
      • English
      • eBook
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      This book provides an update on the step-by-step "how to" methods for the study mitochondrial structure, function, and biogenesis contained in the successful first edition. As in the previous edition, the biochemical, cell biological, and genetic approaches are presented along with sample results, interpretations, and pitfalls from each method.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 98
      • April 3, 2007
      • George F. Vande Woude + 1 more
      • English
      • Paperback
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      • Hardback
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      • eBook
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      The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. A very special event the Nobel Minisymposium, “Molecular Oncology – From Bench to Bedside,” held at the Karolinska Instituet, in Stockholm, Sweden, was marked the celebration of George and Eva Klein’s combined 160th birthday. To honor this occasion, this 2nd of two volumes brings together contributions by their former students, colleagues and collaborators of the past fifty years into a volume of Advances in Cancer Research dedicated to George and Eva. Over a decade ago, a subdivision of ACR called “Foundations in Cancer Research” was initiated and the tributes honoring the Kleins’ bodies of work presented at the minisymposium are especially appropriate for the series.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 97
      • April 2, 2007
      • George F. Vande Woude + 1 more
      • English
      • Hardback
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      • eBook
        9 7 8 0 0 8 0 4 8 8 2 0 2
      The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. A very special event the Nobel Minisymposium, “Molecular Oncology – From Bench to Bedside,” held at the Karolinska Instituet, in Stockholm, Sweden, was marked the celebration of George and Eva Klein’s combined 160th birthday. To honor this occasion, this volume brings together contributions by their former students, colleagues and collaborators of the past fifty years into a volume of Advances in Cancer Research dedicated to George and Eva. Over a decade ago, a subdivision of ACR called “Foundations in Cancer Research” was initiated and the tributes honoring the Kleins’ bodies of work presented at the minisymposium are especially appropriate for the series.

    • Biomedical Ethics for Engineers

      • 1st Edition
      • March 30, 2007
      • Daniel A. Vallero
      • English
      • Hardback
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      • Paperback
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      Biomedical Ethics for Engineers provides biomedical engineers with a new set of tools and an understanding that the application of ethical measures will seldom reach consensus even among fellow engineers and scientists. The solutions are never completely technical, so the engineer must continue to improve the means of incorporating a wide array of societal perspectives, without sacrificing sound science and good design principles.Dan Vallero understands that engineering is a profession that profoundly affects the quality of life from the subcellular and nano to the planetary scale. Protecting and enhancing life is the essence of ethics; thus every engineer and design professional needs a foundation in bioethics. In high-profile emerging fields such as nanotechnology, biotechnology and green engineering, public concerns and attitudes become especially crucial factors given the inherent uncertainties and high stakes involved. Ethics thus means more than a commitment to abide by professional norms of conduct. This book discusses the full suite of emerging biomedical and environmental issues that must be addressed by engineers and scientists within a global and societal context. In addition it gives technical professionals tools to recognize and address bioethical questions and illustrates that an understanding of the application of these measures will seldom reach consensus even among fellow engineers and scientists.

    • Foundations of Comparative Genomics

      • 1st Edition
      • March 30, 2007
      • Arcady R. Mushegian
      • English
      • Hardback
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      • Paperback
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      • eBook
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      This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics.

    • Radicals for Life

      • 1st Edition
      • March 26, 2007
      • Ernst van Faassen + 1 more
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included.

Related subjects

Biochemistry biophysics

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Life sciences general

Molecular biology cellular biology and genetics

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