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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Cilia: Model Organisms and Intraflagellar Transport

      • 1st Edition
      • Volume 93
      • November 23, 2009
      • English
      • Hardback
        9 7 8 0 1 2 3 8 1 3 7 7 0
      • eBook
        9 7 8 0 1 2 3 8 1 3 7 8 7
      Cilia are highly conserved organelles that serve motile functions, sensory functions, or both. These organelles power cell movement, generate fluid flow in various organs, act as sensors of the extracellular environment and have been modified for various specialized tasks such as light reception and smell. Defects in these ubiquitous organelles lead to a broad array of human genetic disorders that range from polycystic kidney disease, retinal degeneration, epilepsy and infertility to developmental defects such as situs inversus and polydactyly. This volume is the third in a three-part series on cilia that focuses on the use of model organisms to gain insight into ciliary function and on the process of intraflagellar transport that is essential for the assembly and maintenance of ciliary structures.
    • Guide to Protein Purification

      • 2nd Edition
      • Volume 436
      • November 19, 2009
      • Richard R Burgess + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 7 4 9 7 8 9
      • eBook
        9 7 8 0 0 8 0 9 6 1 1 5 6
      Guide to Protein Purification, Second Edition provides a complete update to existing methods in the field, reflecting the enormous advances made in the last two decades. In particular, proteomics, mass spectrometry, and DNA technology have revolutionized the field since the first edition’s publication but through all of the advancements, the purification of proteins is still an indispensable first step in understanding their function. This volume examines the most reliable, robust methods for researchers in biochemistry, molecular and cell biology, genetics, pharmacology, biotechnology and sets a standard for best practices in the field. It relates how these traditional and new cutting-edge methods connect to the explosive advancements in the field. This "Guide to" gives imminently practical advice in order to avoid costly mistakes in choosing a method and brings in perspective from the premier researchers while it presents a comprehensive overview of the field today.
    • Osteoporosis in Men

      • 2nd Edition
      • November 17, 2009
      • Eric S. Orwoll + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 6 0 2 3
      • eBook
        9 7 8 0 0 8 0 9 2 3 4 6 8
      Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.
    • Cell Biology Assays

      • 1st Edition
      • November 16, 2009
      • Fanny Jaulin + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 7 5 6 9 2 3
      • eBook
        9 7 8 0 1 2 3 7 5 6 9 3 0
      Protein assay methods are used for protein identification with blood groups, cell surface markers, drugs and toxins. This text features comprehensive protocols essential for researchers studying various areas of biological and medical sciences. The techniques in this text are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls while enabling researchers at all stages to embark on basic problems using a vareity of technologies and model systems.
    • Natural Killer Cells

      • 1st Edition
      • November 12, 2009
      • Michael T. Lotze + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 0 4 5 4 2
      • eBook
        9 7 8 0 0 8 0 9 1 9 2 9 4
      Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine.
    • Tissue-Specific Vascular Endothelial Signals and Vector Targeting, Part A

      • 1st Edition
      • Volume 67
      • November 12, 2009
      • English
      • Hardback
        9 7 8 0 1 2 3 7 5 0 1 0 5
      • eBook
        9 7 8 0 0 8 0 9 6 2 4 6 7
      The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.This thematic volume reviews the latest research findings in the area of vascular proteomics related to the receptors of the vascular endothelium, and expands insights into diseases that exhibit distinct vascular characteristics, including cancer, obesity, and inflammation.
    • Biothermodynamics, Part B

      • 1st Edition
      • Volume 466
      • November 11, 2009
      • Michael L. Johnson + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 7 7 6 1
      • eBook
        9 7 8 0 0 8 0 8 8 7 8 1 4
      The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.
    • Advances in Microbial Physiology

      • 1st Edition
      • Volume 56
      • November 10, 2009
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 7 9 1 4
      • eBook
        9 7 8 0 0 8 0 8 8 8 3 1 6
      Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 56th volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to traditional views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series.