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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Regenerative Medicine and Biomaterials for the Repair of Connective Tissues

      • 1st Edition
      • January 12, 2010
      • Charles Archer + 1 more
      • English
      • eBook
        9 7 8 1 8 4 5 6 9 7 7 9 2
      Regenerative medicine for the repair of connective tissues is a fast moving field which generates a lot of interest. Unfortunately the biomaterials and biomechanics for soft tissue repair has been under-represented in the past. Particularly the natural association between cartilage, tendons and ligaments is often not made.Regenerative medicine and biomaterials for the repair of connective tissues addresses this gap in the market by bringing together the natural association of cartilage, tendons and ligaments to provide a review of the different structures, biomechanics and, more importantly, provide a clear discussion of practical techniques and biomaterials which may be used to repair the connective tissues.Part one discusses cartilage repair and regeneration with chapters on such topics as structure, biomechanics and repair of cartilage. Chapters in Part two focus on the repair of tendons on ligaments with particular techniques including cell-based therapies for the repair and regeneration of tendons and ligaments and scaffolds for tendon and ligament tissue engineering.

    • Lipid Analysis

      • 4th Edition
      • January 10, 2010
      • W. W. Christie + 1 more
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 4 6 5 3
      • Hardback
        9 7 8 0 9 5 5 2 5 1 2 4 5
      • eBook
        9 7 8 0 8 5 7 0 9 7 8 6 6
      This well-known and highly successful book was first published in 1973 and has been completely re-written in subsequent editions (published in 1982 and 2003). This new Fourth Edition has become necessary because of the pace of developments in mass spectrometry of intact lipids, which has given recognition of lipid analysis and ‘lipidomics’ as a distinct science. To bring the book up to date with these developments, author William W. Christie is joined by co-author Xianlin Han. Although devoting considerable space to mass spectrometry and lipidomics, Lipid analysis remains a practical guide, in one volume, to the complexities of the analysis of lipids. As in past editions, it is designed to act as a primary source, of value at the laboratory bench rather than residing on a library shelf.Lipid analysis deals with the isolation, separation, identification and structural analysis of glycerolipids, including triacylglycerols, phospholipids, sphingolipids, and the various hydrolysis products of these. The chapters follow a logical sequence from the extraction of lipids to the isolation and characterization of particular lipid classes and of molecular species of each, and to the mass spectrometric analysis of lipids and lipidomics.The new influence of mass spectrometry is due mainly to the development of electrospray ionization (ESI) and matrix-assisted laser desorption/ionizatio... (MALDI). Most emphasis in this book is placed on ESI, which is enabling structural characterization of different lipid classes and the identification of novel lipids and their molecular species.

    • Biomaterials and Regenerative Medicine in Ophthalmology

      • 1st Edition
      • December 18, 2009
      • Traian Chirila + 1 more
      • English
      • eBook
        9 7 8 1 8 4 5 6 9 7 4 3 3
      With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology.

    • Drug-Device Combination Products

      • 1st Edition
      • December 15, 2009
      • Andrew Lewis
      • English
      • Hardback
        9 7 8 1 8 4 5 6 9 4 7 0 8
      • eBook
        9 7 8 1 8 4 5 6 9 7 4 8 8
      Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development. Advanced drug delivery devices can offer significant advantages over conventional drugs and devices alone, such as increased efficiency, improved performance and convenience. The purpose of this book is to illustrate how effective drug delivery can be achieved by means other than tablets. The book will provide a thorough analysis of the fundamentals, applications and new technologies of drug-device combination products for use throughout the human body.Part one provides readers with an introduction and background to the field. Chapters in Part two discuss areas of application such as catheter based products, drug eluting stents and beads and anti-biotic loaded cements. Part three covers the development of drug device combination products with chapters on such topics as pre-clinical testing, sterilisation, patent issues and regulation of drug device combination products.With its distinguished editor and team of international contributors, Drug-device combination products: delivery technologies and applications is an invaluable reference for product development specialists, materials scientists and engineers in the biomedical industry and academia as well as those concerned with drug delivery.

    • Primary Cilia

      • 1st Edition
      • Volume 94
      • November 30, 2009
      • English
      • Hardback
        9 7 8 0 1 2 3 7 5 0 2 4 2
      • eBook
        9 7 8 0 0 8 0 9 6 2 8 2 5
      In recent years, the role of cilia in the study of health, development and disease has been increasingly clear, and new discoveries have made this an exciting and important field of research. This comprehensive volume, a complement to the new three-volume treatment of cilia and flagella by King and Pazour, presents easy-to-follow protocols and detailed background information for researchers working with cilia and flagella.

    • Cilia: Structure and Motility

      • 1st Edition
      • Volume 91
      • November 27, 2009
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 9 7 3 4
      • eBook
        9 7 8 0 0 8 0 9 6 1 0 6 4
      Along with its companion volume on intraflagellar transport, this book provides researchers with a comprehensive and up-to-date source of methods for the analysis cilia and flagella, focusing primarily on approaches that have been devised or significantly extended since the last volume of Methods in Cell Biology on this topic (volume 47, 1995). Edited by Stephen M. King and Gregory J. Pazour, the newest installment of this highly acclaimed serial will serve as an essential addition to the study of cilia and flagella.

    • Structural Genomics, Part B

      • 1st Edition
      • Volume 76
      • November 26, 2009
      • Andrzej Joachimiak
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 4 4 2 5
      • eBook
        9 7 8 0 0 8 0 9 2 2 3 8 6
      Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.

    • Structural Genomics, Part C

      • 1st Edition
      • Volume 77
      • November 26, 2009
      • English
      • Paperback
        9 7 8 0 3 2 3 1 6 3 7 7 4
      • Hardback
        9 7 8 0 1 2 3 8 1 4 4 3 2
      • eBook
        9 7 8 0 1 2 3 8 1 4 4 4 9
      Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.

    • Advances in Protein Chemistry and Structural Biology

      • 1st Edition
      • Volume 78
      • November 26, 2009
      • David S. Eisenberg + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 8 2 7 0
      • Paperback
        9 7 8 0 3 2 3 1 6 3 9 3 4
      • eBook
        9 7 8 0 0 8 0 8 8 8 7 1 2
      Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This eclectic volume features articles on a variety of topical subjects.

    • Cilia: Motors and Regulation

      • 1st Edition
      • Volume 92
      • November 23, 2009
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 9 7 4 1
      • eBook
        9 7 8 0 0 8 0 9 6 1 0 7 1
      Along with its companion volume on axonemal dynein-mediated motility, this book provides researchers with a comprehensive and up-to-date source of methods for the analysis cilia and flagella, focusing primarily on approaches that have been devised or significantly extended since the last volume of Methods in Cell Biology on this topic (volume 47, 1995). Edited by Stephen M. King and Gregory J. Pazour, the newest installment of this highly acclaimed serial will serve as an essential addition to the study of cilia and flagella.

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