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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Gastroenteropancreatic System and Its Tumors: Part II, An Issue of Endocrinology and Metabolism Clinics

      • 1st Edition
      • Volume 40-1
      • March 21, 2011
      • Aaron I. Vinik
      • English
      • Hardback
        9 7 8 1 4 5 5 7 0 4 4 0 8
      This two-part issue of Endocrinology and Metabolism Clinics of North America provides the endocrinologist with comprehensive essential updates about tumors of the gastroenteropancreat... system. Topics covered include the history and development of the gastroenteropancreat... endocrine axis; the changing face and epidemiology of neuroendocrine tumors (NETs); chromogranins current state of the art, pathology of gastroenteropancreat... (GEP) disorders; new and emerging syndromes related to gastrointestinal (GI) hormones; an update on incretins; prospects for ghrelin in the clinic, obesity/appetite and hedonism; GI motility disorders; gastric bypass and GI hormones; pancreatic exocrine function and GI hormones; harnessing the pancreatic stem cell; how to diagnose NETs before there are METs; NETs in kids: combining the SEER data for children and adults with site differences; novel biomarkers for NETs; standard imaging techniques for NETs; novel peptide imaging: glucagon receptor; signaling mechanism in NETs as targets for therapy; update on clinical trials; nutrition and the GEP; peptide radiotherapy; in vitro analysis of NETs: the role of angiogenesis; modern lab evaluation of peptide and amines: a continuing role for radioimmunoassay?; surgery/surgical management of NETs; and evaluation and quality of life in NETs patients.
    • Methods in Methane Metabolism, Part B

      • 1st Edition
      • Volume 495
      • March 17, 2011
      • Amy Rosenzweig + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 9 0 5 0
      • eBook
        9 7 8 0 1 2 3 8 6 9 0 6 7
      Produced by microbes on a large scale, methane is an important alternative fuel as well as a potent greenhouse gas. This volume focuses on microbial methane metabolism, which is central to the global carbon cycle. Both methanotrophy and methanogenesis are covered in detail. Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems, and field measurements. The state of the art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field.
    • Activins and Inhibins

      • 1st Edition
      • Volume 85
      • March 7, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 5 9 6 1 7
      • eBook
        9 7 8 0 1 2 3 8 5 9 6 2 4
      First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.This volume focuses on activins and inhibins.
    • Introduction to Biomedical Engineering

      • 3rd Edition
      • March 7, 2011
      • John Enderle + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 9 7 9 6
      • eBook
        9 7 8 0 0 8 0 9 6 1 2 1 7
      Introduction to Biomedical Engineering is a comprehensive survey text for biomedical engineering courses. It is the most widely adopted text across the BME course spectrum, valued by instructors and students alike for its authority, clarity and encyclopedic coverage in a single volume. Biomedical engineers need to understand the wide range of topics that are covered in this text, including basic mathematical modeling; anatomy and physiology; electrical engineering, signal processing and instrumentation; biomechanics; biomaterials science and tissue engineering; and medical and engineering ethics. Enderle and Bronzino tackle these core topics at a level appropriate for senior undergraduate students and graduate students who are majoring in BME, or studying it as a combined course with a related engineering, biology or life science, or medical/pre-medical course. NEW: Each chapter in the 3rd Edition is revised and updated, with new chapters and materials on compartmental analysis, biochemical engineering, transport phenomena, physiological modeling and tissue engineering. Chapters on peripheral topics have been removed and made avaialblw online, including optics and computational cell biology NEW: many new worked examples within chapters NEW: more end of chapter exercises, homework problems NEW: image files from the text available in PowerPoint format for adopting instructors Readers benefit from the experience and expertise of two of the most internationally renowned BME educators Instructors benefit from a comprehensive teaching package including a fully worked solutions manual
    • Animal Models of Human Disease

      • 1st Edition
      • Volume 100
      • March 4, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 4 8 7 8 9
      • eBook
        9 7 8 0 1 2 3 8 4 8 7 9 6
      Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. Animal Models of Human Disease reviews the latest research and developments in this field.
    • Fragment Based Drug Design

      • 1st Edition
      • Volume 493
      • February 28, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 1 2 7 4 2
      • eBook
        9 7 8 0 1 2 3 8 1 2 7 5 9
      There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits.
    • Biomedical Hydrogels

      • 1st Edition
      • February 26, 2011
      • Steve Rimmer
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 7 4 1 8
      • Hardback
        9 7 8 1 8 4 5 6 9 5 9 0 3
      • eBook
        9 7 8 0 8 5 7 0 9 1 3 8 3
      Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel’s interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians.
    • Biothermodynamics, Part D

      • 1st Edition
      • Volume 492
      • February 16, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 0 0 3 3
      • eBook
        9 7 8 0 1 2 3 8 6 0 0 4 0
      The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.
    • The Unfolded Protein Response and Cellular Stress, Part C

      • 1st Edition
      • Volume 491
      • February 14, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 5 9 2 8 0
      • eBook
        9 7 8 0 1 2 3 8 5 9 2 9 7
      This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights
    • Cancer and Development

      • 1st Edition
      • Volume 94
      • February 14, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 0 9 1 6 2
      • eBook
        9 7 8 0 1 2 3 8 0 9 1 7 9
      In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors.