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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • The Genetics of Circadian Rhythms

      • 1st Edition
      • Volume 74
      • September 16, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 7 6 9 0 4
      • eBook
        9 7 8 0 1 2 3 8 7 6 9 8 0
      This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
    • Computational Chemistry Methods in Structural Biology

      • 1st Edition
      • Volume 85
      • September 13, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 4 8 5 7
      • eBook
        9 7 8 0 1 2 3 8 6 4 8 6 4
      Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This volume features articles on Computational Chemistry methods in Structural Biology.
    • DNA Repair in Cancer Therapy

      • 1st Edition
      • September 12, 2011
      • Mark R. Kelley
      • English
      • eBook
        9 7 8 0 1 2 3 8 5 0 0 0 3
      Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease. However, cancer is a tough opponent in this battle, and current treatments, which typically include radiotherapy, chemotherapy and surgery, are not often enough to rid the patient of his or her cancer. Cancer cells can become resistant to the treatments directed at them, and overcoming this drug resistance is an important research focus. Additionally, increasing discussion and research is centering on targeted and individualized therapy. While a number of approaches have undergone intensive and close scrutiny as potential approaches to treat and kill cancer (signaling pathways, multidrug resistance, cell cycle checkpoints, anti-angiogenesis, etc.), other approaches have focused on blocking the ability of a cancer cell to recognize and repair the damaged DNA that primarily results from the front-line cancer treatments; chemotherapy and radiation. This comprehensive and timely reference focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment.
    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 55
      • September 8, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 8 7 0 4 2 1
      • eBook
        9 7 8 0 1 2 3 8 7 0 4 3 8
      Volume 55 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
    • The Zebrafish: Genetics, Genomics and Informatics

      • 3rd Edition
      • Volume 135
      • September 7, 2011
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 8 1 4 0
      • eBook
        9 7 8 0 0 8 0 8 8 8 5 7 6
      This volume on genetics, genomics, and informatics, will cover new technologies in forward and reverse genetics, transgenesis, the zebrafish genome and mapping technologies, informatics and comparative genomics, and Infrastructure. This volume of Methods in Cell Biology will prove valuable both to seasoned zebrafish investigators as well as to those who are newly adopting the zebrafish model as part of their research armamentarium.
    • Handbook of Neuroendocrinology

      • 1st Edition
      • August 31, 2011
      • George Fink + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 5 0 9 7 6
      • eBook
        9 7 8 0 1 2 3 7 8 5 5 4 1
      Neuroendocrinology, the discipline concerned with how the nervous system controls hormonal secretion and how hormones control the brain, is pivotal to physiology and medicine. Neuroendocrinology has disclosed and underpins fundamental physiological, molecular biological and genetic principles such as the regulation of gene transcription and translation, the mechanisms of chemical neurotransmission and intracellular and systemic feedback control systems. Reproduction, growth, stress, aggression, metabolism, birth, feeding and drinking and blood pressure are some of the bodily functions that are triggered and/or controlled by neuroendocrine systems. In turn, neuroendocrine dysfunction due to genetic or other deficits can lead, for example, to infertility, impotence, precocious or delayed puberty, defective or excessive growth, obesity and anorexia, Cushing’s Syndrome, hypertension or thyroid disorders. These as well as neuroendocrine tumors are some of the themes covered in the 36 chapters of the Handbook. Drafted by internationally acknowledged experts in the field, the Handbook chapters feature detailed up-to-date bibliographies as well as "how do we know?" call out sections that highlight the experimental or technical foundations for major concepts, principles, or methodological advances in each area. Aimed at senior undergraduate and graduate students, post-doctoral fellows and faculty in neuroscience, medicine, endocrinology, psychiatry, psychology and cognate disciplines, the Handbook of Neuroendocrinology satisfies an unmet need that will prove useful at the laboratory bench as well as in the office.
    • Therapeutic Applications of Quadruplex Nucleic Acids

      • 1st Edition
      • August 31, 2011
      • Stephen Neidle
      • English
      • Hardback
        9 7 8 0 1 2 3 7 5 1 3 8 6
      • Paperback
        9 7 8 0 1 2 8 1 0 3 7 2 2
      • eBook
        9 7 8 0 1 2 3 7 5 1 3 9 3
      The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much current activity on the design of quadruplex-selective small-molecule ligands and the study of their cellular effects. This timely publication gives a uniquely integrated view of quadruplex nucleic acids that will be a major resource in future drug-discovery strategies. Therapeutic Applications of Quadruplex Nucleic Acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics. Written by a world leader in this field, this book is a vital resource for researchers in medicinal chemistry, chemical biology, structural biology, drug discovery, and pharmacology in cancer and other therapeutic areas, as well as for chemists and biologists working on nucleic acids, and will be useful for both active researchers and students in these areas.
    • Signals and Systems for Bioengineers

      • 2nd Edition
      • August 29, 2011
      • John Semmlow
      • English
      • Hardback
        9 7 8 0 1 2 3 8 4 9 8 2 3
      • eBook
        9 7 8 0 1 2 3 8 4 9 8 3 0
      Signals and Systems for Bioengineers, Second Edition, is the only textbook that relates important electrical engineering concepts to biomedical engineering and biological studies. It explains in detail the basic engineering concepts that underlie biomedical systems, medical devices, biocontrol, and biosignal analysis. It is perfect for the one-semester bioengineering course usually offered in conjunction with a laboratory on signals and measurements which presents the fundamentals of systems and signal analysis. The target course occupies a pivotal position in the bioengineering curriculum and will play a critical role in the future development of bioengineering students. This book provides increased coverage of time-domain signal analysis as well as biomeasurement, using examples in ultrasound and electrophysiology. It also presents new applications in biocontrol, with examples from physiological systems modeling such as the respiratory system. It contains double the number of Matlab and non-Matlab exercises to provide ample practice solving problems - by hand and with computational tools. More biomedical figures are found throughout the book. For instructors using this text in their course, an accompanying website (www.elsevierdirect.... in Semmlow page) includes support materials such as MATLAB data and functions needed to solve the problems, a few helpful routines, and all of the MATLAB examples. Intended readers include biomedical engineering students, practicing medical technicians, mechanical engineers, and electrical engineers.