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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Motilin

      • 1st Edition
      • December 2, 2012
      • Zen Itoh
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 4 7 7 9
      • eBook
        9 7 8 0 3 2 3 1 5 7 8 9 6
      Motilin focuses on the pharmacology and physiology of motilin, with emphasis on its relationship to interdigestive motor activities and species differences between these two parameters. Changes in plasma motilin in relation to some gastrointestinal diseases, including peptic ulcer, cholelithiasis, chronic idiopathic constipation, dumping syndrome, and irritable bowel syndrome, are discussed. This book is comprised of 17 chapters and begins with a historical background on motilin, including its discovery and isolation. The next chapter considers the structure of motilin in pigs and cats and presents evidence for the existence of motilin in other species. The chemical synthesis, radioimmunoassay, and immunoreactivity of motilin are also examined. Subsequent chapters explore the prohormone of human motilin; morphological identification of motilin in the gut; mechanisms of motilin excitation as determined by in situ and in vitro studies; and motilin receptors. This monograph should be of interest to scientists, physiologists, clinical specialists, morphologists, pharmacologists, and biochemists.

    • Data Analysis in Biochemistry and Biophysics

      • 1st Edition
      • December 2, 2012
      • Magar Mager
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 4 2 0 0
      • eBook
        9 7 8 0 3 2 3 1 4 7 3 8 5
      Data Analysis in Biochemistry and Biophysics describes the techniques how to derive the most amount of quantitative and statistical information from data gathered in enzyme kinetics, protein-ligand equilibria, optical rotatory dispersion, chemical relaxation methods. This book focuses on the determination and analysis of parameters in different models that are used in biochemistry, biophysics, and molecular biology. The Michaelis-Menten equation can explain the process to obtain the maximum amount of information by determining the parameters of the model. This text also explains the fundamentals present in hypothesis testing, and the equation that represents the statistical aspects of a linear model occurring frequently in this field of testing. This book also analyzes the ultraviolet spectra of nucleic acids, particularly, to establish the composition of melting regions of nucleic acids. The investigator can use the matrix rank analysis to determine the spectra to substantiate systems whose functions are not known. This text also explains flow techniques and relaxation methods associated with rapid reactions to determine transient kinetic parameters. This book is suitable for molecular biologists, biophysicists, physiologists, biochemists, bio- mathematicians, statisticians, computer programmers, and investigators involved in related sciences

    • Molecular Orbital Theory In Drug Research

      • 1st Edition
      • December 2, 2012
      • Lemont Kier
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 5 1 5 8
      • eBook
        9 7 8 0 3 2 3 1 5 8 2 7 5
      Medicinal Chemistry, Volume 10: Molecular Orbital Theory in Drug Research is a 12-chapter text that emerged from a series of lectures presented to graduate students in medicinal chemistry at the University of Michigan. After dealing with the general considerations of drug phenomena and quantum theory, this book goes on exploring the various molecular orbital calculation methods and the significance of molecular orbital indices. The subsequent chapters on the applications of molecular orbital theory are organized on the basis of physical chemical phenomena concluded from the studies described to be involved in the biological activity. These chapters also look into the correlations between indices reflecting covalent bond formation and biological activity. This text further examines the charge transfer mechanisms of several drug classes. The remaining chapters are devoted to the use of molecular orbital theory in several aspects of drug research, including molecular conformation, acid-base phenomena, hydrogen bonding, and dispersion forces. This work is directed to the advanced undergraduate or graduate students in medicinal chemistry or pharmacology, as well as to the practicing scientists interested in acquiring some understanding of molecular orbital theory. Theoretical chemists seeking information on biological phenomena amenable to semiempirical molecular orbital study will find this book invaluable.

    • Methods in Mammalian Reproduction

      • 1st Edition
      • December 2, 2012
      • Joseph C. Jr. Daniel
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 2 0 4 6
      • Hardback
        9 7 8 0 1 2 2 0 1 8 5 0 3
      • eBook
        9 7 8 0 3 2 3 1 4 5 2 0 6
      Methods in Mammalian Reproduction presents some of the techniques for manipulating, analyzing, observing, testing, and generally experimenting with mammalian mothers and their gametes and embryos. Mammalian reproduction involves an intimate relationship between mother and embryo. The first 18 chapters are arranged in an order that follows a developmental sequence from oocyte to fetal organs and the remaining seven chapters deal with the maternal side of the relationship. With strong focus on laboratory rodents and lagomorphs, the book starts with an introduction to in vitro oocyte maturation and experimental production of mammalian parthenogenetic. It goes on to describe the microtechniques in pre-implantation of embryos, production of chimeras, techniques for early embryonic tissue separation, mammalian embryo preservation by freezing, and in vitro development of whole mouse embryos beyond the implantation stage. Chapters 11-15 discuss the in vitro implantation of mouse blastocysts, advances in rabbit embryo and in large mammal embryo cultures, embryo transfer in large domestic mammals, and manipulation of marsupial embryos and pouch young. The following chapters cover reproduction experiments using marsupials, domestic farm species, and primates including humans. Finally, the concluding chapters tackle the use of amniocentesis in prenatal diagnosis, collection and analysis of female genital tract secretions, analysis of antifertility action of intrauterine devices, and surgical induction of endometriosis. This book will be helpful to students, teachers, researchers, and clinical researchers who demand for more and better procedures for analysis of mammalian reproduction.

    • A New Look at Mechanisms In Bioenergetics

      • 1st Edition
      • December 2, 2012
      • Efraim Racker
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 6 9 1 9
      • Hardback
        9 7 8 0 1 2 5 7 4 6 7 0 0
      • eBook
        9 7 8 0 3 2 3 1 6 0 1 1 7
      A New Look at Mechanisms in Bioenergetics features eight lectures based on the Robbins Lectures given at Pomona College in April 1973. These lectures are based mainly on the author's own laboratory work and are intended for students of biology and biochemistry who want to devote their lives to research. Lecture 1 presents some of the general lessons learned from research in the field of bioenergetics. It also discusses methods for measuring oxidative phosphorylation and the resolution of soluble multienzyme systems. Lecture 2 explains the biochemical approach to the problem of photophosphorylation... Lecture 3 considers the intersection of oxidative phosphorylation and membranology. Lecture 4 discusses the coupling device and its partial reactions. Lecture 5 focuses on the oxidation chain in mitochondria. Lecture 6 discusses the resolution and reconstitution of oxidative phosphorylation. Lecture 7 examines the reconstitution of ion pumps. Finally, Lecture 8 covers oxidation control in glycolysis; the high aerobic glycolysis of tumor cells; ATPases in tumor cells; and the repair of ion pumps in tumor cells.

    • Comparative Diagnosis of Viral Diseases

      • 1st Edition
      • December 2, 2012
      • Edouard Kurstak
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 9 0 8
      • Hardback
        9 7 8 0 1 2 4 2 9 7 0 4 3
      • eBook
        9 7 8 0 3 2 3 1 4 3 0 5 9

    • Control Mechanisms in the Expression of Cellular Phenotypes

      • 1st Edition
      • December 2, 2012
      • Helen Padykula
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 4 0 2 1
      • Hardback
        9 7 8 0 1 2 6 1 1 9 0 9 1
      • eBook
        9 7 8 0 3 2 3 1 5 7 1 4 8
      Control Mechanisms in the Expression of Cellular Phenotypes documents the proceedings of a symposium of the International Society for Cell Biology. In progressively widening investigations, phenotypic expression has come to a critical focus not only in the developmental biology of animal and plant cells, but also in such fields as immunology, cytogenetics, enzymatic regulation, and tumor biology. It was for this reason that the present symposium was organized as a means of bringing together investigators of widely different backgrounds. The contributions made by researchers at the symposium include studies on gene expression in allophenic mice; the regulation of uridine 5-monophosphate synthesis in human diploid cells; the melanotic expression of embryonic pigment cells; and clonal cell lines of neurons. Other papers deal with biochemical genetics studies on mammalian cells in vitro; embryos from somatic plant cells; somatic cell hybrids as tools for genetic studies in man; and utilization of somatic cells for genetic analysis.

    • Laterality Functional Asymmetry in the Intact Brain

      • 1st Edition
      • December 2, 2012
      • M Bryden
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 7 3 4 5
      • eBook
        9 7 8 0 3 2 3 1 5 5 4 2 7
      Laterality: Functional Asymmetry in the Intact Brain focuses on brain function and laterality as well as the various methods in assessing behavioral asymmetries, including handedness. It reviews the literature on perceptual-cognitive laterality effects in different sensory modalities, the lateralization of emotion and motor behavior, and the electrophysiological evidence. It also highlights some of the problems with the existing research and offers suggestions about the direction of future research. Organized into 17 chapters, this volume begins with an overview of cerebral asymmetry and the origins and mechanisms of lateralization. Then, it discusses the individual differences in laterality, methods and measurement used in laterality studies, and experiments on dichotic listening and auditory lateralization. The next chapters focus on the link between verbal laterality and handedness, tactual and perceptual laterality, asymmetry of motor performance, lateralization of emotional processes, and physiological measures of asymmetry. The book also introduces the handedness and its relation to cerebral function, genetics of laterality, development of cerebral lateralization, individual differences in cerebral organization, sex differences in laterality, reading- and language-related deficits, and control of the active hemisphere before concluding with a chapter discussing the experimental or strategy effects, the concept of complementary specialization, and the dichotomy between the two hemispheres of the brain. This book is a valuable resource for neuropsychologists, experimental psychologists, neurologists, and educators interested in understanding human brain function.

    • Xenobiotics and Inflammation

      • 1st Edition
      • December 2, 2012
      • Schook + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 0 6 3 1
      • eBook
        9 7 8 0 3 2 3 1 4 0 3 6 2
      The affect of xenobiotics on host resistance in general and specific immune functions has become the focus of much current research. This book synthesises current information on how chemicals (xenobiotics) can affect the immune system to cuse dysfunction, focusing on the process of inflammation. It provides a much needed, single-source reference for researchers investigation the mechanisms responsible for altered host resistance following exposture to xenobiotics. Emphasis is placed on the roles of cytokines and growth factors in the inflammatory process and how such processes are altered and modulated by xenobiotics. This volume contains information pertinent to those exploring cell growth, angiogenesis, hematopoetic differentiation, and recruitment to and proliferation of cells in various tissue sites. This volume brings together experts in inflammation, cytokines, cell growth, immunology and toxicology to provide a highly yseful volume modulated by chemicals. Divided into three sections, the book offers an organ system approach to understanding inflammation and xenobiotics.

    • Free Radicals in Biology V2

      • 1st Edition
      • December 2, 2012
      • William Pryor
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 3 0 0 0
      • eBook
        9 7 8 0 3 2 3 1 5 6 1 0 3
      Free Radicals in Biology, Volume II is a nine-chapter text that describes the complexities in the chemical and physical behavior of free radicals. After briefly providing an overview of the biology of pyridinyl radicals, this book goes on discussing the role of glutathione in the cell and the reactions of single oxygen and its role in photochemical smog and in cellular chemistry. These topics are followed by a discussion on the production of free radicals from dry tissue. The subsequent chapters describe some of the key reactions in photochemical smog, including reaction studies by computer simulation, as well as the specific reactive materials that are present in smog. These chapters also look into the chemistry of nitrogen oxides and ozone, which are some of the most important reactions in photochemical smog. The concluding chapters explore the radiation damage to proteins and radiation protection and radical reactions produced by radiation in nucleic acids. Chemists, biologists, and physicists will find this text invaluable.

Related subjects

Biochemistry biophysics

Biotechnology

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Life sciences general

Molecular biology cellular biology and genetics

Physiology