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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Laboratory Methods in Vesicular and Vectorial Transport

      • 1st Edition
      • December 2, 2012
      • Alan Tartakoff
      • English
      • Paperback
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      Laboratory Methods in Vesicular and Vectorial Transport describes the procedures used to study the mechanisms of vesicular transport along the secretory and endocytic paths, including electron microscopy, autoradiography, and methods associated with cyto- and immunocytochemistry, genetics, and biochemistry. It investigates vectorial transport to the cisternal space of the rough endoplasmic reticulum (ER), as well as protein translocation across the ER, strategies for gaining access to the cytoplasm, cell-free analysis of vesicle fusion, the structure of glycoproteins, and the use of cell systems for analysis of vesicular traffic. Organized into seven parts encompassing 20 chapters, this volume begins with an overview of protein topology in the ER and the use of cross-linking methods to probe the molecular environment of translocating polypeptide chains. It then discusses the reconstitution of secretory protein translocation from detergent-solubilize... rough microsomes; the use of anti-idiotype antibodies to characterize protein-protein interactions; the use of perforated cells to elucidate intracellular membrane transport; delivery of macromolecules into cells expressing a viral membrane fusion protein; and digitonin permeabilization procedures for studying endosome acidification and function. The reader is also introduced to reconstitution of intracellular vesicle fusion in a cell-free system after receptor-mediated endocytosis; immunoisolation using magnetic solid supports; endosome and lysosome purification by free-flow electrophoresis; remodeling of glycoprotein oligosaccharides after endocytosis; and replica plating of animal cells. This book will interest students, researchers, geneticists, biochemists, and cell biologists.

    • The Ontogeny of Vertebrate Behavior

      • 1st Edition
      • December 2, 2012
      • Howard Moltz
      • English
      • Paperback
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      • Hardback
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      The Ontogeny of Vertebrate Behavior is a collection of articles focused on the comparative psychology researches. The text is devoted to the development of vertebrate behavior, emphasizes the ontogenetic determinants, and answers questions related to the differentiation of selected response systems. The book is organized into 10 chapters that feature the concepts of vertebrate behavior and its ontogeny. It presents the study of behavioral development, as well as the visual perceptual systems and its evolution. It explains the perceptual abilities of the human infant and the early experience and problem-solving behavior. Cerebral effects of environmental manipulation and the behavioral phenomena are explained. The book also talks about the ontogeny of emotional, play, and exploratory behaviors; of sexuality and maternal behavior; and of mother-infant relations. It also discusses the principle and procedure of imprinting. Finally, it explains the vocal learning of avian species and the ontogeny of language, as well as the vocal abnormalities. This text will be invaluable to the students, novices, and professionals in psychology, ethology, endocrinology, and behavioral and developmental biology.

    • Lithium and the Cell

      • 1st Edition
      • December 2, 2012
      • Nicholas J. Birch
      • English
      • Paperback
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      • eBook
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      This up-to-date compilation addresses the scientific problems of determining a mode of action of lithium and provides a cross-disciplinary perspective. In addition to psychiatrists interested in the therapeutic uses of lithium, it will also be of interest to biochemists using lithium as an inhibitor of phosphoinositide signaling, immunologists studying lymphocytes, and dermatologists studying viral replication in the skin.

    • Cyclic AMP

      • 1st Edition
      • December 2, 2012
      • G Robison
      • English
      • Paperback
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      • Hardback
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      Cyclic AMP provides information pertinent to cyclic adenosine 3',5'-monophosphate (AMP), a regulatory agent that controls the rate of a number of cellular processes. This book discusses the heat-stable factor mediating the action of glucagon and epinephrine on the activation of liver phosphorylase. Organized into 12 chapters, this book starts with an overview of the biological role of cyclic AMP, which is extended from a relatively simple role in liver glycogenolysis to a significant regulatory agent in most mammalian tissues. This text then discusses the development that led to the discovery of the heat-stable factor from investigations with cyclic nucleotides. Other chapters explore the chemical agents, which are released from one group of cells and travel via the bloodstream to affect one or more different groups of cells. The final chapter discusses the role of cyclic AMP to mammalian physiology, with emphasis on the many possible defects that may lead to human disease. This book is a valuable resource for graduate students and clinical investigators involved in biological and biomedical sciences.

    • Neuronal and Glial Proteins

      • 1st Edition
      • December 2, 2012
      • Paul Marangos
      • English
      • Paperback
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      • eBook
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      Neuronal and Glial Proteins: Structure, Function, and Clinical Application focuses on the basic and clinical information relating to a number of proteins that are either enriched in or unique to nervous tissue. This book discusses the structural and functional characteristics of cell-specific proteins, which provide a better understanding of the molecular mechanisms involved in processes that are specific to glia or neurons. Organized into three sections encompassing 15 chapters, this book starts with an overview of the fundamental principles and strategies involved in studying the anatomical, structural, functional, and immunological aspects of brain protein. This text then discusses the techniques, including the preparation of brain tissues as well as the preparation of neural and glial cells in purified form. Other chapters review the two-dimensional gel electrophoresis, which is recognized as a significant technique for discovering brain molecules. The final chapter deals with the membrane-associated nervous system proteins. Neurochemists and clinical researchers will find this book useful.

    • Plant Cold Hardiness and Freezing Stress

      • 1st Edition
      • December 2, 2012
      • P.H. Li
      • English
      • Paperback
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      • eBook
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      Plant Cold Hardiness and Freezing Stress: Mechanisms and Crop Implications, Volume 2 contains the proceedings of an International Seminar on Plant Cold Hardiness, held at the Sapporo Educational and Cultural Hall, Sapporo, Japan on August 11-14, 1981. Organized into five parts, this book aims to update the fundamental phenomena of plant cold acclimation and freezing behavior, to examine the hypotheses and ideas important to plant cold hardiness research, and to review the application of research findings for improving the quality of life. This volume particularly addresses the cold acclimation, freezing, and other temperature-related stresses in plants. Strategies for improving freezing survival are also presented. This volume will make an additional, significant contribution to researchers involved in understanding and planning research strategies for plant cold hardiness and for attenuating crop losses by frosts and severe winters.

    • Catalytic in Organic Syntheses 1976

      • 1st Edition
      • December 2, 2012
      • Paul Rylander
      • English
      • Paperback
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      Catalysis in Organic Syntheses 1976 provides information pertinent to organic chemistry and the practical applications of catalysis. This book reviews the influence of mass and heat transport on the performance of heterogeneous catalysts. Organized into five parts encompassing 17 chapters, this compilation of papers starts with an overview of how the formulation of the catalyst and the selection of operating conditions influence the chemistry of the reactions that occur. This text then examines the Auger electron spectroscopy (AES), which is a powerful tool for the analysis of surface and subsurface elemental composition in the fields of metallurgy, semiconductors, and thin films. Other chapters consider the importance of differential thermal analysis (DTA) as a useful method for rapidly screening potential catalysts. The final chapter deals with the rhodium-catalyzed nuclear hydrogenation of N-aryl amides, which is an excellent laboratory method for the preparation of N-alicyclic amides. This book is a valuable resource for organic and catalytic chemists.

    • Viral Insecticides for Biological Control

      • 1st Edition
      • December 2, 2012
      • Karl Maramorosch
      • English
      • Paperback
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      Viral Insecticides for Biological Control focuses on the basic as well as applied aspects of viral insecticides, which have the potential to significantly reduce the current reliance on chemical pesticide technology. This book serves as a guide for the development of means to identify hazardous problems and prevent them. Organized into six parts with a total of 23 chapters, this book describes the taxonomy, nomenclature, identification, physical, biological, as well as chemical characteristics, replication, and pathology of insect viruses. This reference material also explores the dispersal, stability, and utilization of insect viruses as biological control agents. The factors and considerations that must be taken into account when a viral insecticide is sought as a large-scale commercial alternative to other more traditional methods of pest control are also addressed. Because this reference material collates information in this field of interest, it will benefit a wide audience of readers, including researchers, students, and those working directly in crop protection.

    • Enzymes as Targets for Drug Design

      • 1st Edition
      • December 2, 2012
      • Michael Palfreyman
      • English
      • Paperback
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      • eBook
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      Enzymes as Targets for Drug Design is a collection of scientific discussions related to enzyme inhibitors that show the many facets of the drug discovery process from the basic sciences through clinical applications. Topics include the biogenesis of phosphatidylinositol glycosyl membrane proteins, structure and catalytic function of ADP-ribose polymerase (ADPRT), and modulation of the dopaminergic system in cardiovascular therapeutics. The therapeutic utility of selected enzyme-activated irreversible inhibitors, the role of proteinases in the fibrosis of systemic sclerosis, and therapeutic opportunities in eicosanoid biosynthesis are also discussed. This book consists of 18 chapters and begins with examples of enzymes whose activities have recently been elucidated, or for which newer insights have been gleaned, but which do not yet have selective or potent inhibitors. The second part provides examples of enzymes where inhibitors have been identified but it is still not clear whether or not such an enzymatic blockade will be therapeutically beneficial. The final section describes clinical studies of newer, and not so new, enzyme inhibitors that are clearly of therapeutic importance. The therapeutic activity of monoamine oxidase inhibitors and the associated clinical issues are considered. This book is intended for clinicians as well as basic scientists in biochemistry, chemistry, pharmacology, and cell biology.

    • Photochemistry and Photobiology of Nucleic Acids

      • 1st Edition
      • December 2, 2012
      • Shih Yi Wang
      • English
      • Paperback
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      • Hardback
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      Photochemistry and Photobiology of Nucleic Acids: Volume II, Biology is a collection of papers that deals with the biological effects due to stable UV induced alterations in critical cellular macromolecules, including cell death, growth delay, mutagenesis, and carcinogenesis. The papers assume that DNA is the macromolecule most relevant to cell pathology, as well as to the photochemical and photobiological properties of RNA which are essential in cellular functions. One paper investigates the UV-induced cross-linkings of proteins with nucleic acids as a possible cause of biological effects other than just in terms of the damage done to nucleic acids. Other papers discuss the mechanisms of protection against, and in the repair of damage caused by UV photons and by ionizing radiation (also chemical mutagens) in many organisms from viruses to mammalian cells. The repair processes appear to play a role in monitoring and preserving the structural integrity of DNA during physiological processes such as replication and transcription. One paper notes that in experiments on human embryonic lung fibroblasts WI-38 at very high radiation doses, radiation products of Thy in acid-soluble form appear while products from the DNA (acid-precipitable fraction) disappear. The paper suggests that the excision process is therefore selective. The collection is suitable for biochemists, microbiologists, or academicians whose works involve genetics, cancer, and cellular research.

Related subjects

Biochemistry biophysics

Biotechnology

Endocrinology

Life sciences general

Molecular biology cellular biology and genetics

Physiology