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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression

      • 1st Edition
      • December 2, 2012
      • Marianne Grunberg-Manago
      • English
      • Paperback
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      Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression presents the proceedings of the Fogarty International Conference on Translational/Transc... Regulation of Gene Expression, held at the National Institutes of Health in Bethesda, Maryland, on April 7-9, 1982. Speakers discussed the molecular strategies at work during the modulation of gene expression following transcriptional initiation. They also discussed recent developments in a number of key areas in which transcriptional and translational components interact. Organized into five sections encompassing 36 chapters, this volume explores both prokaryotic and eukaryotic systems, as well as structure-function correlations. It begins with an overview of translational/transc... controls in prokaryotes, the regulation of gene expression by transcription termination and RNA processing, and the structure and expression of initiation factor genes. It then examines the effect of the codon context on translational fidelity, including mistranslation of messenger RNA; protein synthesis for the construction of cell architecture; regulation of initiation factor activity; and translational regulation in cells. This book is a valuable resource for Fogarty International Scholars who want to broaden their knowledge and contribute their expertise to the National Institutes of Health community.
    • Cellular Membranes in Development

      • 1st Edition
      • December 2, 2012
      • Michael Locke
      • English
      • Paperback
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      Cellular Membranes in Development covers the proceedings of the 1963 22nd Symposium on ""The Society for the Study of Development and Growth"" held in Storrs, Connecticut. This book is organized into 10 chapters that discuss the properties, isolation, function, composition, and physiological aspects of membranes. After briefly dealing with the principles of the unit membrane concept, the book describes the properties of lipid membranes of bilayer thickness with biological relevance. The next chapter focuses on hepatic cell and the modifications of the endoplasmic reticulum in cell differentiation in normal and cancerous growth. Another chapter describes the developmental changes in a particular experimental systems and the modification of the membranes by specific treatments using the apical portion of the primary root of Zea mays. The book also discusses the role of the different organelles in development, supporting the idea of topological continuity between the membranes of all the organelles except the mitochondria. Other chapters describe the cytology of oogenesis and fertilization in Pteridium aquilinum; the early events of fertilization in Hydroides and Saccoglossus; and the composition of cell walls of bacteria, yeast, and fungi. Some aspects of the capsules, microcapsules, and sheaths exhibited by some microorganisms are also covered. The last chapters deal with the quantitative aspects of plant cell permeation and permeability function and changes in relation to maturation and growth hormones. The book is an ideal source for cell biologists and researchers, evolutionists, and biochemists.
    • Newer Methods of Nutritional Biochemistry V1

      • 1st Edition
      • December 2, 2012
      • Anthony Albanese
      • English
      • Paperback
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      • Hardback
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      Newer Methods of Nutritional Biochemistry: With Applications and Interpretations, Volume I, provides graduate biochemistry students and medical scientists with a compilation of biochemical procedures which have extensive applications in nutrition research. To this end, several approaches to further exploration of protein, carbohydrate, and fat metabolism and the interrelationship with enzymes, vitamins, and minerals are covered in some detail. Comprised of 11 chapters, this book discusses proteins and amino acids; utilization of dietary proteins; intestinal absorption; diet and tissue enzymes; and rates and the kinetics of enzyme formation and destruction in the living animal. It considers vitamins B1, B2, B6, niacin, and ascorbic acid; vitamin B12 and intrinsic factor; carbohydrates; fats, fatty acids, and sterols; minerals; and biostatistical methods for nutritional and metabolic investigations.
    • Germfree Life And Gnotobiology

      • 1st Edition
      • December 2, 2012
      • Thomas Luckey
      • English
      • Paperback
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      Germfree Life and Gnotobiology focuses on the theory and general aspects of germfree research and gnotobiology. Using a phylogenetic approach, the book provides a summary of germfree work in all phyla, from bacteria and viruses to protozoans and invertebrates. It characterizes germfree vertebrates based on data on morphology, biochemistry, nutrition, serology, and physiology. This book is organized into six chapters and begins with an overview of germfree life and gnotobiology, including biological isolation as the basis of germfree life, germfree conditions in nature, and the biological significance of germfree research. A section is devoted to nomenclature and terminology. The chapters on methods and nutrition are sufficiently detailed to serve as guides for experimental work. The book concludes with a chapter on exploratory research that explores the inoculation of germfree animals with known kinds of microorganisms. Terms have been introduced to describe concepts and provide precise communication. This book is a valuable source of information for scientists and researchers engaged in germfree research as a biological tool.
    • Cation Flux Across Biomembranes

      • 1st Edition
      • December 2, 2012
      • Yasuo Mukohata
      • English
      • Paperback
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      • Hardback
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      Cation Flux Across Biomembranes documents the proceedings of a symposium on ""Cation Flux across Biomembranes"" sponsored by the Japan Bioenergetics Group, held September 10-13, 1978 at the Inter-University Seminar House of Kansai in Kobe, Japan. The symposium brought together 80 of the leading investigators concerned with ATP-utilizing and ATP-generating systems associated with cation fluxes across membranes to discuss biochemical mechanisms in depth and their relation to cation transport functions. The papers presented focused on three types of membrane systems. The first two membrane systems are classified as ATP-utilizing systems. These include the plasma membrane, associated with the ATP dependent Na+-K+ transport system, which draws upon most of the cell's energy for cation fluxes; and the sarcoplasmic recticulum membrane associated with Ca++ transport, which plays a key role in excitation-contracti... coupling in muscle. The third type of membrane system falls under ATP-generating systems. These include the inner membranes of mitochondria, chloroplasts, and bacteria associated with H+ fluxes generated by oxidation-reduction reactions, and their coupling to secondary ion flows and oxidative and photosynthetic phosphorylation. H+ transport associated with the photoreaction cycle of bacteriorhodopsin, the light energy converted in halobacteria was also considered.
    • Invertebrate Tissue Culture

      • 1st Edition
      • December 2, 2012
      • Karl Maramorosch
      • English
      • Paperback
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      Invertebrate Tissue Culture: Research Applications covers the broad field and status of basic research in invertebrate tissue culture. This book particularly discusses invertebrate cell growth and differentiation, cloning of established cell lines, the breakthrough in molluscan tissue culture, and the establishment of the first snail line. It also highlights topics on invertebrate endocrinology and ecdysone biosynthesis in vitro. This text describes the identification of distinct juvenile hormones from corpora allata and the production of peptide neurohormones by cultured insect brains. Some chapters elucidate the use of Drosophila discs in vitro to study gene activity sites, as well as the applications of insect tissue culture to the study of intracellular parasites, symbionts, and arboviruses. Discussions on insect pathogenic viruses in insect cell lines, extraneous contaminants in invertebrate cell cultures, uses of invertebrate cells in plant pathology, and a description of invertebrate cell lines complete this volume. This reference will be valuable to microbiologists, parasitologists, virologists, entomologists, geneticists, and medical researchers working in the field and to graduate students in related fields of biomedical research.
    • Metabolic Inhibitors V4

      • 1st Edition
      • December 2, 2012
      • R Hochster
      • English
      • Paperback
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      Metabolic Inhibitors: A Comprehensive Treatise, Volume IV reviews developments in studies of inhibition of metabolic and enzymic processes ranging from photosynthesis and blood clotting to protein synthesis, fatty acid metabolism, and phospholipid metabolism. The book also explores the inhibition of specific enzyme reactions, such as amino acid activation, amino acid hydroxylation, and cyclic AMP formation. Organized into nine chapters, this volume begins with an overview of allosteric inhibition and inhibitors, and then discusses amino acid hydroxylase inhibitors. The reader is also introduced to inhibitors and activators of enzymes that regulate the cellular concentration of cyclic AMP. In particular, the book describes the role of lipids in the activation of adenyl cyclase by hormones; modification of adenyl cyclase in various physiological and pathological conditions; and synthesis of glycerophosphatides as well as phospho- and glycosphingolipids. This book is a valuable source of information for biochemists and medical research workers as well as virologists, microbiologists, plant physiologists, and agronomists.
    • The Emergency of Order in Developing Systems

      • 1st Edition
      • December 2, 2012
      • Michael Locke
      • English
      • Paperback
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      The Emergence of Order in Developing Systems is a collection of papers presented at the 27th Symposium of the Society for Developmental Biology, held in Ithaca, New York in June 1968. Contributors focus on the emergence of orderly patterns during development, touching on topics ranging from the three-dimensional structure of the protein molecule to the polymerization of structural units, the self-assembly of microtubules in axonemes, and the patterning of plant cell walls. This volume is organized into four sections encompassing 11 chapters and begins with an overview of the emergence of order during cellular differentiation and growth, paying particular attention to the spontaneous formation of the three-dimensional structure of proteins. The next chapters explore self-association reactions in solutions of myosin molecules; ordering of subcellular units; factors that order the distribution of microtubules and thus ultimately pattern the shape of the cell; the biochemical organization of cytoplasmic membranes through self-assembly; and patterning in cell walls of higher plants. The book also explains the emergence of order in tissues and organs, and then concludes with a discussion on the emergence of order on the behavioral level. This book will be of interest to developmental biologists and embryologists.
    • Intracellular Parasitic Protozoa

      • 1st Edition
      • December 2, 2012
      • Masamichi Aikawa
      • English
      • Paperback
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      Intracellular Parasitic Protozoa introduces the basic structure and classification of intracellular parasitic protozoa and the concept of parasitism. This book starts by discussing the concept of parasitism and the taxonomic background of various intracellular protozoan organisms. This is followed by a description of the relationships between intracellular protozoan and their host cells. Then, this book discusses the ultrastructure of cells and organisms, emphasizing cell morphology that serves as the primary basis of generalizations of the host cell-parasite relationships. It also presents the intracellular protozoa in several groups according to their probable taxonomic relationships and more obvious morphological similarities. Finally, this text describes protozoan fine structure, along with a brief discussion of their biological aspects. This book is ideal for researchers, teachers, and students who wish to gain more knowledge in parasitism caused by intracellular protozoa.
    • Interferons

      • 1st Edition
      • December 2, 2012
      • Thomas Merigan
      • English
      • Paperback
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      Interferons documents the proceedings of a major international conference on Chemistry and Biology of Interferons: Relationship to Therapeutics held at Squaw Valley, California, in March 1982. The meeting was one of the 1982 UCLA Symposia on Molecular and Cellular Biology organized through the Molecular Biology Institute of the University of California at Los Angeles. The book is organized into four parts. Part I presents papers on recombinant DNA production of interferon. It includes studies on the synthesis of human immune interferon in E. coli and monkey cells; the expression of human β interferon gene in heterologous cells; and the molecular activities of recombinant and hybrid leukocyte interferons. Part II deals with the biology of interferons, covering topics such as interferon production control process; the effect of interferon on cellular enzymes; and human amniotic interferon. Part III examines the factors relevant to clinical application of interferons, including structure-function studies with human interferon-gamma and on human alpha interferon. Part IV presents clinical studies of interferon, such as interferon α trials in human tumor diseases and interferon in renal transplant recipients.