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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Mechanisms of Release of Biogenic Amines

      • 1st Edition
      • May 16, 2014
      • U. S. Von Euler + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 6 7 2 3
      • eBook
        9 7 8 1 4 8 3 1 4 9 1 4 1
      Wenner-Gren Center International Symposium Series, Volume 5: Mechanisms of Release of Biogenic Amines provides information pertinent to the fundamental aspects of the release of biogenic amines. This book discusses the physiology, biochemistry, and pharmacology of the biogenic amines. Organized into 39 chapters, this volume begins with an overview of the release of amines, which is implicated in functional disturbances characteristic of different diseases. This text then examines the concepts of cell structure that are significant to the release of neurohumoral agents. Other chapters consider the fluorescence reaction, which made it possible to work out a practical histochemical procedure. This book describes as well a few examples in which the monoaminergic transmitter is not revealed as a diffuse cytoplasmic fluorescence. The final chapter deals with acetylcholine as the only brain amine investigated, which could be influenced by the tremorgenic agents during the period of tremor. This book is a valuable resource for biochemists, morphologists, pharmacologists, and physiologists.

    • Regulation of Secondary Product and Plant Hormone Metabolism

      • 1st Edition
      • May 18, 2014
      • M. Luckner + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 2 7 3 6
      • eBook
        9 7 8 1 4 8 3 1 8 8 5 4 6
      Regulation of Secondary Product and Plant Hormone Metabolism contains the proceedings of the 12th Meeting of the Federation of European Biochemical Societies held in Dresden, Germany in 1978. The meeting provided a forum for discussing progress in understanding the regulation of the metabolism of secondary products and plant hormones. It shows that the processes regulating secondary metabolism are similar in lower and higher plants, and that the molecular basis of cell differentiation and specialization is uniform in all groups of living organisms. Comprised of 22 chapters, this volume begins with an overview of the interrelationships between secondary products and hormones in plants, followed by a detailed account of the effects of phenolic compounds on auxin biosynthesis and vice versa. The reader is then introduced to non-ribosomal biosynthesis of biologically active peptides; channelling of intermediates during the biosynthesis of cyanogenic glycosides; and intracellular distribution of flavonoids in glandular cells. Subsequent chapters explore the regulation of gene expression in secondary biosynthesis; inhibition of phenylalanine ammonia-lyase by cinnamic acid derivatives; novel inhibitors of phenylpropanoid metabolism in higher plants; and stage-specific phenylpropanoid metabolism during pollen development. This book will be of interest to biochemists and geneticists.

    • Database Directory and Master Indices

      • 1st Edition
      • May 10, 2014
      • Edwin J. Atencio + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 5 4 2 7
      • eBook
        9 7 8 1 4 8 3 2 1 8 8 5 4
      Nucleotide Sequences 1986/1987, Volume VIII: Database Directory and Master Indices presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into 13 sections, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main emphasis in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.

    • Amines and Schizophrenia

      • 1st Edition
      • May 16, 2014
      • Harold E. Himwich + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 4 6 7 4
      • Hardback
        9 7 8 0 0 8 0 1 2 0 3 9 3
      • eBook
        9 7 8 1 4 8 3 1 5 7 0 9 2
      Amines and Schizophrenia is a collection of articles that survey and discuss the biochemical basis present, if any, in schizophrenia, focusing on the role of certain amines. The book discusses certain hypotheses dealing with the field of bio-chemistry as the basis for diseases such as schizophrenia, manic-depressive psychosis, and related diseases. Discussions start with the properties of mescaline, because the psychotic effect of the drug has some aspects similar to that of a schizophrenic syndrome. One paper examines the presence of certain amines, such as norepinephrine, dopamine, and serotonin in the brain, including their role in the synaptic transmission of nerve impulses in the central nervous system. Other papers review the role of derangements of tryptophan metabolism in psychotic behavior; the metabolic interrelationships of tryptophan and methionine in mental illness; and the results obtained with psychomimetic and non-psychomimetic congeners of three classes of indoleamines including LSD. The book gives more details on the actions of various biological amines on single neurons in the limbic system of the brain. The text also evaluates the use of hallucinogenic drugs in considering their heuristic value in the study of the biochemical basis of mental function. The selection will prove relevant for psychologists, psychiatrists, drug researchers, pharmacologists, and chemical laboratory workers and technicians.

    • Translational Systems Biology

      • 1st Edition
      • October 8, 2014
      • Yoram Vodovotz + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 1 4 7 6
      • Hardback
        9 7 8 0 1 2 3 9 7 8 8 4 4
      • eBook
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      Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money’s worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the underpinning of biomedical research for the future. By using a combination of essays providing the intellectual basis of the Translational Dilemma and reports of examples in the study of inflammation, the content of Translational Systems Biology will remain relevant as technology and knowledge advances bring broad translational applicability to other diseases. Translational systems biology is an integrated, multi-scale, evidence-based approach that combines laboratory, clinical and computational methods with an explicit goal of developing effective means of control of biological processes for improving human health and rapid clinical application. This comprehensive approach to date has been utilized for in silico studies of sepsis, trauma, hemorrhage, and traumatic brain injury, acute liver failure, wound healing, and inflammation.

    • Essays in Biochemistry

      • 1st Edition
      • November 26, 2014
      • K. F. Tipton
      • English
      • Paperback
        9 7 8 0 1 2 1 5 8 1 2 5 1
      • eBook
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      Essays in Biochemistry, Volume 25 provides information on the developments in the continually changing field of biochemistry. Each chapter of the book is written by an expert on the area of research. The volume contains contributions that deal with such topics as intracellular protein degradation; the metabolic heterogeneity of liver parenchymal cells; and the biochemistry of ethanol metabolism and the pathogenesis of alcoholic liver disease (ALD). Biochemistry and neurochemistry in the 1800 and their origins in comparative animal chemistry is discussed extensively in the final chapter. Biochemists will find the book very informative.

    • The Evolution of the Bioenergetic Processes

      • 1st Edition
      • May 18, 2014
      • E. Broda
      • English
      • Paperback
        9 7 8 0 0 8 0 2 2 6 5 1 4
      • eBook
        9 7 8 1 4 8 3 1 3 6 1 3 4
      The Evolution of the Bioenergetic Processes deals with the evolution of the bioenergetic processes, from fermentation to photosynthesis and respiration, and their interrelationships in prokaryotes and eukaryotes. Topics covered range from the origin of life to the evolution of eobionts, organisms, and energy-rich compounds. Fermentation, photoorganotrophy, and photosynthesis in bacteria and plants are also discussed. Comprised of 25 chapters, this book begins with an overview of energy and entropy in the biosphere, followed by a detailed treatment of the evolution of bioenergetics based on the pattern of the bioenergetic processes in extant organisms. The reader is then introduced to the events involved in the origin of life; the evolution of eobionts and organisms; and the origin of energy-rich compounds, particularly nucleotides of the adenylic acid system. Subsequent chapters focus on fermentation and photosynthesis; assimilation of carbon dioxide; photoorganotrophy, chemolithotrophy, and photolithotrophy; and aerobic and anaerobic respiration of prokaryotes. The book also considers the energy supply of protozoa and fungi before concluding with an analysis of the history of atmospheric oxygen. This monograph will be of interest to evolutionary biologists.

    • The Mouse in Biomedical Research

      • 1st Edition
      • May 10, 2014
      • Henry L. Foster + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 8 9 8 2
      • eBook
        9 7 8 1 4 8 3 2 6 2 7 6 5
      The Mouse in Biomedical Research, Volume III: Normative Biology, Immunology, and Husbandry focuses on the normative biology, immunology, and husbandry of laboratory mice. Topics covered range from gnotobiotics and gastrointestinal microflora to animal health surveillance and health delivery systems, along with environmental monitoring. The management and design of breeding and research facilities are also discussed. Comprised of 18 chapters, this volume begins with an overview of studies involving gnotobiotic mice, the induction of gnotobiosis, and microbiological testing of gnotobiotic animals. Maintenance of breeding colonies of gnotobiotic animals is also considered, together with the shipment of gnotobiotes and laboratory facilities for using gnotobiotes. The reader is then introduced to management and design of breeding and research facilities for gnotobiotic mice; practical factors associated with providing adequate nutrition for laboratory mice; and environmental and equipment monitoring. Subsequent chapters deal with the basic biology of the mouse, including anatomy, embryology, reproductive physiology, physiology, endocrinology, hematology, clinical biochemistry, and gastrointestinal microflora. The book also examines immunoglobulins and immunoglobulin genes; lymphocyte immunogenetics; immune response disorders; and biomethodology and surgical techniques. This monograph will be useful to biologists, immunologists, researchers, and others those who use mice in the laboratory or are concerned with the production and maintenance of colonies of mice.

    • In Vitro Methods in Cell-Mediated Immunity

      • 1st Edition
      • June 28, 2014
      • Barry R. Bloom + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 6 3 6 0
      • eBook
        9 7 8 1 4 8 3 2 7 7 5 9 2
      In Vitro Methods in Cell-Mediated Immunity focuses on methods for approaching cell-mediated immune responses in vitro. This book provides, in simplified in vitro systems, a basis for understanding the mechanism of the in vivo response and discusses useful and reliable in vitro tests for cell-mediated immune responses in humans, where in vivo testing is often not possible. The topics discussed include factors and activities produced in vitro by lymphocytes; biological implications of in vitro phenomena; and requirements and prospects for improved methodology. The leucocyte migration technique for in vitro detection of cellular hypersensitivity in man; proliferation of human blood lymphocytes stimulated by antigen in vitro; and virus plaque assay for antigen-sensitive are also elaborated in this text. This publication is a good reference for microbiologist and immunologists, including medical students researching on in vitro models for cell-mediated immune reactions.

    • Protides of the BIological Fluids

      • 1st Edition
      • Volume 30
      • November 26, 2014
      • H. Peeters
      • English
      • eBook
        9 7 8 1 4 8 3 2 7 9 6 4 0
      Protides of the Biological Fluids: Proceedings of the 30th Colloquium, 1982 is a collection of manuscripts presented at the 30th Colloquium, held in Brussels, Belgium in 1982. This text is organized into three sections encompassing 160 chapters. The first section highlights the mechanisms of the normal and abnormal mental function through evaluation of neuroproteins or the so-called “think-proteins”. This section describes the manifestations, clinical features, diagnosis, and therapeutic options of nervous system diseases. The second section tackles monoclonal proteins as a reagent to detect antigens. This section deals with the significant progress in cancer therapy and the binding of cytotoxic drugs to monoclonal antibodies. The third section considers the potential of isodalt electrophoresis and high-pressure liquid chromatography, with particular emphasis on their application to protein analysis in biological fluids. This book will be of great value to biochemists, clinical chemists, and clinicians.

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