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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • The Antigens

      • 1st Edition
      • May 10, 2014
      • Michael Sela
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 6 4 4 4
      • eBook
        9 7 8 1 4 8 3 2 6 9 5 6 6
      The Antigens, Volume III is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from microbial polysaccharides and lymphocytic receptors for antigens to antigenic determinants and antibody-combining sites. Allergens and the genetics of allergy are also explored. Comprised of seven chapters, this volume begins with a review of microbial polysaccharides as antigens, followed by a discussion on antigenic determinants and their specific reaction with antibody-combining sites. The reader is then introduced to the reaction of antigens with their specific receptors on lymphocytes. The next four chapters are concerned with several categories of more complex antigens which, in most cases, have yet to be characterized adequately at a molecular level: allergens, histocompatibility antigens, antigens of Mycoplasmatales and chlamydiae, and animal viruses. The book concludes with an analysis of virus infections and the immune responses they elicit. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

    • Essential Treatments in Cardiovascular Chinese Medicine 1: Hyperlipidemia

      • 1st Edition
      • April 9, 2014
      • Anika Niambi Al-Shura
      • English
      • Paperback
        9 7 8 0 1 2 8 0 0 1 1 9 6
      • eBook
        9 7 8 0 1 2 8 0 0 6 3 7 5
      Essential Treatments in Cardiovascular Chinese Medicine includes information on the basic medical sciences of blood lipids, clinical significance, diagnosis, and treatment methods. It also covers TCM differentiations, diagnosis, treatment principles, and methods. In recent years, TCM practitioners have not been specifically trained in treating patients with hyperlipidemia. The book gives a detailed explanation of cholesterol problems and offers Chinese medicine as a solution. This book is intended for US-based licensed TCM practitioners as well as cardiology researchers.

    • Footprinting of Nucleic Acid-Protein Complexes

      • 1st Edition
      • May 19, 2014
      • English
      • Paperback
        9 7 8 0 1 2 5 8 6 5 0 0 5
      • eBook
        9 7 8 1 4 8 3 2 9 5 0 1 5
      Footprinting of Nucleic Acid-Protein Complexes provides protocols for studying the stoichiometry, binding site size and location, and structural changes in nucleic acids caused by their interaction with proteins. The methods are central to studying key biological processes, such as transcription and translation. The techniques are important to experiments in vivoand in vitro, in eukaryotes and in prokaryotes, at qualitative and quantitative levels,and across many disciplines.This book is a laboratory manual of footprinting techniques for studying nucleic acid-protein interactions. It contains clear and concise descriptions of the most important methodologies, and includes in vivo as well as in vitro applications. It is aimed at bench scientists from graduate students on, and should be of value in industrial labs as well as in academic settings. Use of different footprinting approaches can provide unique insights into DNA-protein systems. The protocols containedin this handbook are written to be"user-friendly,"an... thus should be conducive to extending the use of footprinting to new systems. The section on quantitative analysis of DNAse I footprints should prove especially useful for in depth evaluation of cooperative interactions.

    • Lipids: Structure and Function

      • 1st Edition
      • Volume 9
      • May 19, 2014
      • P. Michael Conn
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 4 6 3 9
      • eBook
        9 7 8 1 4 8 3 2 9 6 7 1 5
      The Biochemistry of Plants: A Comprehensive Treatise, Volume 9: Lipids: Structure and Function focuses on the advancements in the methodologies, principles, techniques, and technologies involved in plant lipid research. The selection first elaborates on the analysis and structure determination of acyl lipids, oxidative systems for modification of fatty acids, and lipases. Topics include lipid acyl hydrolases, properties of the lipoxygenase reaction, metabolism of the hydroperoxide products of lipoxygenase, physical and chemical methods of structure determination, and chromatographic methods of separation. The manuscript then examines the biosynthesis of saturated fatty acids, biochemistry of plant acyl carrier proteins, and biosynthesis of monoenoic and polyenoic fatty acids. Discussions focus on polyunsaturated fatty acid biosynthesis and regulation, molecular biology, and immunological characterization of acyl carrier proteins. The publication ponders on lipids of blue-green algae, lipid-derived defensive polymers and waxes and their role in plant-microbe interaction, sulfolipids, and galactolipid synthesis. The selection is a vital source of information for researchers interested in the structure and functions of lipids.

    • Analytical Applications of Immobilized Enzymes and Cells

      • 1st Edition
      • Volume 3
      • June 28, 2014
      • Lemuel B. Wingard + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 4 2 6
      • eBook
        9 7 8 1 4 8 3 2 1 5 8 5 3
      Analytical Applications of Immobilized Enzymes and Cells, Volume 3 presents a survey of the interdisciplinary interactions, developments, and trends on research in immobilized enzymes and cells. This volume is comprised of eight chapters. Chapters 1 to 4 are devoted to the description of methodologies and instrumentations which are used in routine analysis. Among those described are enzyme tubes, enzyme thermistors, and enzymic or microbial electrodes. Chapter 4 provides a theoretical analysis of electrode design. Subsequent chapters focus on solid-phase enzyme immunoassays and on techniques for in vivo monitoring of metabolites; economic evaluation of the use of high-purity enzymes in analysis; and an assessment of the significance of microprocessors and computer science in enzyme based analysis. Chemists and chemical engineers will find the book very useful.

    • Alcohol and Abnormal Protein Biosynthesis

      • 1st Edition
      • May 17, 2014
      • Marcus A. Rothschild + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 9 6 4 9
      • eBook
        9 7 8 1 4 8 3 1 5 2 0 6 6
      Alcohol and Abnormal Protein Biosynthesis: Biochemical and Clinical focuses on the methods for measuring protein metabolism and the effects of alcohol and altered protein intake as they affect the heart, liver, skeletal muscle, and the brain. Organized into six sections, this book begins with an overview on malnutrition and alcoholism, as well as available techniques for the study of protein synthesis. Subsequent section details the adaptation of protein synthesis and transport to alcohol and malnutrition. Section three discusses the skeletal and cardiac muscle protein metabolism. The last three sections describe the reaction of hepatic protein synthesis to malnutrition and alcohol; effects of alcohol on brain RNA metabolism; and alcohol associated cardiac and hepatic disease.

    • Toxicogenomics-Based Cellular Models

      • 1st Edition
      • January 2, 2014
      • Jos Kleinjans
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 8 6 2 2
      • eBook
        9 7 8 0 1 2 3 9 7 8 7 1 4
      Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores ‘omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.

    • Biochemical and Molecular Aspects of Selected Cancers

      • 1st Edition
      • May 10, 2014
      • Thomas G. Pretlow + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 4 9 6 9
      • eBook
        9 7 8 1 4 8 3 2 8 2 0 5 3
      Biochemical and Molecular Aspects of Selected Cancers, Volume I provides an overview of important topics and prototypes in cancer research. The book consists of papers provided by outstanding investigators in diverse disciplines in different areas of cancer research. This volume focuses on topics relevant to cancers in humans. It covers such topics as tumor-suppressor genes and human neoplasia; protein kinase C in neoplastic cells; and extracellular matrix interactions with tumor-progressing cells: tumor versus cell type-specific mechanisms. Structural and functional characteristics of human melanoma; steroid hormones and hormone receptors in neoplastic diseases; and patterns and significance of genetic changes in neuroblastomas are expounded as well. Oncologists, biochemists, cytologists, and other researchers in allied fields will find the book invaluable.

    • Brain Metastases from Primary Tumors Volume 1

      • 1st Edition
      • April 3, 2014
      • M. A. Hayat
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 8 9 6 6
      • eBook
        9 7 8 0 1 2 8 0 1 0 9 5 2
      With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection.

    • Biochemistry LabFax

      • 1st Edition
      • June 28, 2014
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 4 4 7 9
      • eBook
        9 7 8 1 4 8 3 2 9 4 4 4 5
      LABFAX volumes are purpose-designed data reference books for practising scientists. Each book presents key information for a major subject in one place and so saves hours of searching. It does not simply collect together data which are already available in catalogues since these are often incomplete and can contain conflicting information. Rather, the authors and editors of each LABFAX volume have searched the original literature for the accurate data which they know the specialist needs.Biochemistry LabFax is a detailed compendium of essential information - on radioisotopes, enzymes, proteins, nucleic acids, lipids, plus data on selected techniques such as chromatography, electrophoresis, etc. - needed on an almost daily basis by researchers in any area of biochemistry. In addition, the book acts as a gateway to other sources for information more specific than can be covered in a volume of this size.

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