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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Exosomes

    A Clinical Compendium
    • 1st Edition
    • October 15, 2019
    • Lawrence R. Edelstein + 3 more
    • English
    Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomesin the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medicaldisciplines, as well as their role in cell-cell communication. It is intended to serve as a referencesource for clinicians, physicians, and research scientists who wish to gain insight into the mostrecent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine sinceantibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is amajor breakthrough in our understanding of how cells function.

  • DNA Repair

    • 1st Edition
    • Volume 45
    • October 15, 2019
    • English
    DNA Repair, Volume 45 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair, Translesion polymerases, mechanism and function, The Rev1-Polζ Mutasome: Structure and Interactions in Translesion Synthesis, Challenges for base excision repair enzymes: acquiring access to damaged DNA in chromatin Nucleotide excision repair, DNA damage recognition mechanisms in mammalian nucleotide excision repair, Advances in understanding DNA mismatch repair, and more.

  • Enzymatic Polymerizations

    • 1st Edition
    • Volume 627
    • October 14, 2019
    • English
    Enzymatic Polymerizations, Volume 627 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Epigenetic Mechanisms of the Cambrian Explosion

    • 1st Edition
    • October 12, 2019
    • Nelson R Cabej
    • English
    Epigenetic Mechanisms of the Cambrian Explosion provides readers with a basic biological knowledge and epigenetic explanation of the biological puzzle of the Cambrian explosion, the unprecedented rapid diversification of animals that began 542 million years ago. During an evolutionarily instant of ~10 million years, which represents only 0.3% of the time of existence of life on Earth, or less than 2% of the time of existence of metazoans, all of the 30 extant body plans, major animal groups (phyla) and several extinct groups appeared. The work helps address this phenomena and tries to answer remaining questions for evolutionary biology, epigenetics, and scientific researchers. The book recognizes and presents objective representations of alternative theories for epigenetic evolution in this period, with the author drawing on his epigenetic theory of evolution to explain the causal basis of the Cambrian explosion. Both empirical evidence and theoretical arguments are presented in support of this thought-provoking epigenetic theory.

  • Plasma Membrane Repair

    • 1st Edition
    • Volume 84
    • October 11, 2019
    • English
    Lysosomes and Membrane Function, Volume 84 in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting interesting chapters on a variety of topics, including Parasite invasion and PMR, Actin dynamics and myosin contractility during plasma membrane repair: Does one ring really heal them all?, The role of intercellular signaling in cell membrane repair, Role of lipids in plasma membrane repair, Lysosomes and plasma membrane repair, Alveolar epithelial cell membrane integrity: a venerable target in the lung, Conservative evolution of natural versus artificial PEG-induced mechanisms of PMR in eukaryotes, and more.

  • Maternal-Fetal and Neonatal Endocrinology

    Physiology, Pathophysiology, and Clinical Management
    • 1st Edition
    • October 9, 2019
    • Christopher S. Kovacs + 1 more
    • English
    Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management systematically examines the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This reference volume expands coverage of specific disorders and diseases beyond the current endocrinology content on the market, which in most cases has a paragraph or no mention at all about pregnancy or aspects of fetal/neonatal development.

  • Improving the Therapeutic Ratio in Head and Neck Cancer

    • 1st Edition
    • Volume 6
    • October 4, 2019
    • English
    Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites.

  • From Globular Proteins to Amyloids

    • 1st Edition
    • October 2, 2019
    • Irena Roterman-Konieczna
    • English
    From Globular Proteins to Amyloids proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in nature and founded upon arguments derived from information theory. It facilitates prediction and simulation of the amyloid fibrillation process, also identifying the progressive changes that occur in native proteins that lead to the emergence of amyloid aggregations.

  • Functional and Clinical Neuroanatomy

    A Guide for Health Care Professionals
    • 1st Edition
    • October 1, 2019
    • Jahangir Moini + 1 more
    • English
    Functional and Clinical Neuroanatomy: A Guide for Health Care Professionals is a comprehensive, yet easy-to read, introduction to neuroanatomy that covers the structures and functions of the central, peripheral and autonomic nervous systems. The book also focuses on the clinical presentation of disease processes involving specific structures. It is the first review of clinical neuroanatomy that is written specifically for nurses, physician assistants, nurse practitioners, medical students and medical assistants who work in the field of neurology. It will also be an invaluable resource for graduate and postgraduate students in neuroscience. With 22 chapters, including two that provide complete neurological examinations and diagnostic evaluations, this book is an ideal resource for health care professionals across a wide variety of disciplines.

  • Computational Modeling in Bioengineering and Bioinformatics

    • 1st Edition
    • October 1, 2019
    • Nenad Filipovic
    • English
    Computational Modeling in Bioengineering and Bioinformatics promotes complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, and in the environment, public health, drug design, and so on. It provides a common platform by bridging these two very important and complementary disciplines into an interactive and attractive forum. Chapters cover biomechanics and bioimaging, biomedical decision support system, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, biomedical image processing, analysis and visualization, high performance computing and sports bioengineering. The book's chapters are the result of many international projects in the area of bioengineering and bioinformatics done at the Research and Development Center for Bioengineering BioIRC and by the Faculty of Engineering at the University of Kragujevac, Serbia.

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