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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Colorectal Neoplasia and the Colorectal Microbiome

      • 1st Edition
      • August 15, 2020
      • Martin H. Floch
      • English
      • Paperback
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      • eBook
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      Colorectal Neoplasia and the Microbiome: Dysplasia, Probiotics, and Fusobacteria provides foundational knowledge on the gut microbiome and evidence for an association with colorectal neoplasia. It covers the role of microbiota in causing adenomatous polyps and colorectal cancer as well as the modulatory effect of diet and probiotics. Chapters explain a foundational history of microbiology in the colon, the epidemiology of colon polyps and cancer, dysbiosis, the role of immunology and bacteria, and the diet. The book combines medical and scientific aspects to show mechanistic aspects between microbiota and hosts, clearly presenting the association between microbiota, colonic lesions and possible causal links. The book is essential reading for everyone working with human microbiota including basic scientists, physiologists of the intestine, experts in intestinal microbiota, gastroenterologists, oncologists and surgeon.

    • Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance

      • 1st Edition
      • Volume 12
      • November 17, 2020
      • Andrew Freywald + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 3 1 0 0
      • eBook
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      Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges.

    • Developmental Human Behavioral Epigenetics

      • 1st Edition
      • Volume 23
      • November 12, 2020
      • Livio Provenzi + 1 more
      • English
      • Paperback
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      • eBook
        9 7 8 0 1 2 8 1 9 2 6 3 4
      Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy.

    • The Cognitive Approach in Cloud Computing and Internet of Things Technologies for Surveillance Tracking Systems

      • 1st Edition
      • March 14, 2020
      • Dinesh Peter + 3 more
      • English
      • Paperback
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      • eBook
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      The Cognitive Approach in Cloud Computing and Internet of Things Technologies for Surveillance Tracking Systems discusses the recent, rapid development of Internet of things (IoT) and its focus on research in smart cities, especially on surveillance tracking systems in which computing devices are widely distributed and huge amounts of dynamic real-time data are collected and processed. Efficient surveillance tracking systems in the Big Data era require the capability of quickly abstracting useful information from the increasing amounts of data. Real-time information fusion is imperative and part of the challenge to mission critical surveillance tasks for various applications. This book presents all of these concepts, with a goal of creating automated IT systems that are capable of resolving problems without demanding human aid.

    • Clinical Bioenergetics

      • 1st Edition
      • November 12, 2020
      • Sergej M. Ostojic
      • English
      • Paperback
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      • eBook
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      Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others.

    • Drug Repurposing in Cancer Therapy

      • 1st Edition
      • July 27, 2020
      • Kenneth K.W. To + 1 more
      • English
      • Paperback
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      • eBook
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      Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.

    • Kidney Biomarkers

      • 1st Edition
      • July 16, 2020
      • Seema S. Ahuja + 1 more
      • English
      • Paperback
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      • eBook
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      Since laboratory testing and biomarkers are an integral part in the diagnosis and treatment of kidney disease, Kidney Biomarkers: Clinical Aspects and Laboratory Determination covers currently used biomarkers as well as markers that are in development. Laboratories are increasingly more involved in the follow-up confirmatory laboratory testing and this unique volume showcases the collaboration needed to solve diagnostic clinical puzzles between the laboratory and clinician. This volume provides guidance on laboratory test selection and results interpretation in patients. Sources of inaccurate results in the measurement of kidney biomarkers are discussed along with possibility of eliminating such interferences. Each chapter is organized with a uniform easy-to-follow format with insightful case examples highlighting the collaboration between clinical laboratorians and clinicians.

    • Diabetes Digital Health

      • 1st Edition
      • April 4, 2020
      • David C. Klonoff + 2 more
      • English
      • Paperback
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      • eBook
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      Diabetes Digital Health brings together the multifaceted information surrounding the science of digital health from an academic, regulatory, industrial, investment and cybersecurity perspective. Clinicians and researchers who are developing and evaluating mobile apps for diabetes patients will find this essential reading, as will industry people whose companies are developing mobile apps and sensors.

    • Biomechanics and Gait Analysis

      • 1st Edition
      • March 25, 2020
      • Nicholas Stergiou
      • English
      • Paperback
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      • eBook
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      Biomechanics and Gait Analysis presents a comprehensive book on biomechanics that focuses on gait analysis. It is written primarily for biomedical engineering students, professionals and biomechanists with a strong emphasis on medical devices and assistive technology, but is also of interest to clinicians and physiologists. It allows novice readers to acquire the basics of gait analysis, while also helping expert readers update their knowledge. The book covers the most up-to-date acquisition and computational methods and advances in the field. Key topics include muscle mechanics and modeling, motor control and coordination, and measurements and assessments. This is the go to resource for an understanding of fundamental concepts and how to collect, analyze and interpret data for research, industry, clinical and sport.

    • Mathematical Approaches to Liver Transplantation

      • 1st Edition
      • March 19, 2020
      • Eduardo Massad + 1 more
      • English
      • Paperback
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      • eBook
        9 7 8 0 1 2 8 1 7 4 3 7 1
      Mathematical Approaches to Liver Transplantation provides mathematical approaches to the optimization of liver graft distribution. Through mathematical and computational methods, several aspects related to organ allocation are tackled, with possible solutions presented. The book discusses topics such as patient selection for liver transplantation, transplantation procedures, dynamics of organs waiting list, improvement on grafts allocation, live donors and MELD scale. The content focuses on liver transplantation, however the mathematical approaches presented can be successfully replicated to different organs. This book is a valuable source for mathematical biologists, bioinformaticians, and several members of biomedical field who are involved in decision-making related to organs transplantation.

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