Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

Books Journals

Pathology

1st Edition
April 25, 2020
Victor R Preedy
English
Paperback
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eBook
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Pathology: Oxidative Stress and Dietary Antioxidants bridges the disciplinary knowledge gap to help advance medical sciences and provide preventative and treatment strategies for pathologists, health care workers, food scientists and nutritionists who have divergent skills. This is important as oxidative stress can be ameliorated with pharmacological, nutraceutical or natural agents. While pathologists and clinical workers understand the processes in disease, they are less conversant in the science of nutrition and dietetics. Conversely, nutritionists and dietitians are less conversant with the detailed clinical background and science of pathology. This book helps to fill those gaps.

A Laboratory Guide to the Tight Junction

1st Edition
April 24, 2020
Jianghui Hou
English
Paperback
9 7 8 0 1 2 8 1 8 6 4 7 3
eBook
9 7 8 0 1 2 8 2 2 6 4 3 8

A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches for tissue fixation and preparation. Chapter 5 discusses Light microscopy, while chapter 6 presents Electron microscopic approaches. Chapter 7 covers Transgenic manipulation in cell cultures, including DNA and siRNA, Mutagenesis, and viral infection. Chapter 8 covers transgenic manipulation in mice, including: Knockout, Knockin, siRNA knockdown, GFP/LacZ reporter, and overexpression. The final chapter discusses the future developments of new approaches for tight junction research. Researchers and advanced students in bioscience working on topics of cell junction, ion channel and membrane protein will benefit from the described methods. Clinicians and pathologists interested in tissue barrier diseases will also benefit from the biochemical and biophysical characterization of tight junctions in organ systems, and their connection to human diseases.

Cell-Derived Matrices Part B

1st Edition
Volume 157
April 23, 2020
David Caballero + 2 more
English
Hardback
9 7 8 0 1 2 8 2 0 1 7 4 9
eBook
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Cell-Derived Matrices Part B, Volume 157 provides a detailed description and step-by-step methods surrounding the use of three-dimensional cell-derived matrices for tissue engineering applications. Chapters in this new release include Glaucomatous cell-derived matrices, Cardiac tissue explants decellularization, Decellularization of skin matrices for wound healing applications, Guiding axonal growth by aligned cell-derived matrices for spinal cord injury regeneration, Human Mesenchymal Stem Cell–Derived Matrices for Enhanced Osteoregeneration, Amniotic decellularized matrices, Three-Dimensional (3-D) Tissue Reconstruction without Scaffold, Tubular cell-derived matrices for TERM applications, and more.

Cell Death Regulation in Health and Disease - Part B

1st Edition
Volume 352
April 22, 2020
Lorenzo Galluzzi + 1 more
English
Hardback
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eBook
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Cell Death Regulation in Health and Disease - Part B, Volume 352, the latest release in the International Review of Cell and Molecular Biology, reviews and details current advances in cell and molecular biology. Chapters in this updated release include Regulation of cell death signaling in insects, Bcl-2 family proteins, Cell death signaling in prokaryotes, Parthanatos in neurodegenerative diseases, Cell death regulation in yeast, Mutual regulation of autophagy and necroptosis, Therapeutic inhibition of cell death by autophagy induction, and Necroptosis in neurodegenerative diseases.

Human Reproductive Genetics

1st Edition
April 19, 2020
Juan A. Garcia-Velasco + 1 more
English
Paperback
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eBook
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Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction.

Protein Interactions as Targets in Drug Discovery

1st Edition
Volume 121
April 17, 2020
Rossen Donev
English
Hardback
9 7 8 0 1 2 8 1 6 8 4 6 2
eBook
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Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interactions. Chapters in this new release include Trends in structure based drug design with protein targets, From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD), Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis, Aromatic-aromatic interactions in protein-drug and protein-protein interactions, Role of protein-protein interaction in allosteric drug design within the human methyltransferome, and much more.

Personalized Computational Hemodynamics

1st Edition
April 16, 2020
Yuri Vassilevski + 4 more
English
Paperback
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eBook
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Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies.

Diabetes

2nd Edition
April 16, 2020
Victor R Preedy
English
Paperback
9 7 8 0 1 2 8 1 5 7 7 6 3
eBook
9 7 8 0 1 2 8 1 5 7 7 7 0

Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer.

Handbook of Clinical Adult Genetics and Genomics

1st Edition
April 10, 2020
Shweta Dhar + 2 more
English
Paperback
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eBook
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Handbook of Clinical Adult Genetics and Genomics: A Practice-Based Approach provides a thorough overview of genetic disorders that are commonly encountered in adult populations and supports the full translation of adult genetic and genomic modalities into clinical practice. Expert chapter authors supplement foundational knowledge with case-based strategies for the evaluation and management of genetic disorders in each organ system and specialty area. Topics discussed include employing genetic testing technologies, reporting test results, genetic counseling for adult patients, medical genetics referrals, issues of complex inheritance, gene therapy, and diagnostic and treatment criteria for developmental, cardiovascular, gastrointestinal, neuropsychiatric, pulmonary issues, and much more.

Advances in Ubiquitous Computing

1st Edition
April 7, 2020
Amy Neustein
English
Paperback
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eBook
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Advances in Ubiquitous Computing: Cyber-Physical Systems, Smart Cities and Ecological Monitoring debuts some of the newest methods and approaches to multimodal user-interface design, safety compliance, formal code verification and deployment requirements, as they pertain to cyber-physical systems, smart homes and smart cities, and biodiversity monitoring. In this anthology, the authors assiduously examine a panoply of topics related to wireless sensor networks. These topics include interacting with smart-home appliances and biomedical devices, designing multilingual speech recognition systems that are robust to vehicular, mechanical and other noises common to large metropolises, and an examination of new methods of speaker recognition to control for the emotion-state of the speaker, which can easily impede speaker verification over a wireless medium. This volume recognizes that any discussion of pervasive computing in smart cities must not end there, as the perilous effects of climate change proves that our lives are not circumscribed by the geographically sculpted boundaries of cities, counties, countries, or continents. Contributors address present and emerging technologies of scalable biodiversity monitoring: pest control, disease transmission, environmental monitoring, and habitat preservation. The need to collect, store, process, and interpret vast amounts of data originating from sources spread over large areas and for prolonged periods of time requires immediate data storage and processing, reliable networking, and solid communication infrastructure, along with intelligent data analysis and interpretation methods that can resolve contradictions and uncertainty in the data—all of which can be bolstered by modern advances in ubiquitous computing.

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