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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Advances in Protein Molecular and Structural Biology Methods

      • 1st Edition
      • January 14, 2022
      • Timir Tripathi + 1 more
      • English
      • Paperback
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      • eBook
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      Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application.
    • Clinical PET/MRI

      • 1st Edition
      • September 7, 2022
      • Onofrio Antonio Catalano
      • English
      • Paperback
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      • eBook
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      Clinical PET/MR presents the state-of-the-art of PET/MR, guiding the reader from how to scan patients, how to read and report the studies, and how keep an eye on what is clinically relevant for a patient’s care. Each chapter starts with the clinical scenario and then moves to pertinent imaging, addressing the need of a clinical PET/MR book written by world experts in both clinical and imaging fields. It discusses the clinical application of PET/MR in diverse subspecialties such as head and neck, neurology, cardiovascular, pediatrics, chest, bone, hematology, breast, hepatobiliary pancreatic, genitourinary, gynecology, and gastrointestinal tract. This book is a valuable resource for radiologists, oncologists and members of the biomedical field who need to learn more about clinical applications of PET/MR.
    • Debulking in Cardiovascular Interventions and Revascularization Strategies

      • 1st Edition
      • January 21, 2022
      • On Topaz
      • English
      • Paperback
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      Debulking in Cardiovascular Interventions and Revascularization Strategies: Between a Rock and the Heart aims to provide a comprehensive overview on the diagnostic and therapeutic aspects of resistant lesions as well as tailored debulking processes in revascularization strategies. Cardiovascular interventionalists and surgeons alike frequently encounter technical challenges and increased risk when attempting to diagnose and treat resistant cardiovascular lesions, bio-tissues and vessels. Calcified plaques, fibrotic or thrombotic lesions, total occlusions, degenerative plaques, complex lesions and vessels impose morphologic obstacles to the safe and effective delivery and deployment of balloons and stents. In such instances, a debulking strategy involving the actual drilling and extraction of the targeted plaque/bio-tissue constitutes a unique option that ensures safe and efficacious subsequent balloon dilatations and stenting. A range of topics is included in the book, from the characteristics and constituents of various resistant targets and bio-tissues, to the corresponding options of debulking methods, and finally the technologic and pharmacologic means available for application. The book also provides an up-to-date description of related management solutions and tools, exploring the medical issues pertaining to the patients with these targets; procedural results and clinical outcomes as related to debulking strategies and associated diagnostic and therapeutic technology and revascularization options.
    • Endocrine Hypertension

      • 1st Edition
      • October 26, 2022
      • Joseph M. Pappachan + 1 more
      • English
      • Paperback
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      • eBook
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      **Selected for Doody’s Core Titles® 2024 in Endocrinology/Metabo... Disease**Endocrine Hypertension: From Basic Science to Clinical Practice bridges the gap between scientists and practicing clinicians by providing a comprehensive overview on all forms of endocrine hypertension, covering epidemiological aspects, pathophysiology, clinical presentation, laboratory evaluation and practical management aspects of endocrine hypertension. This book is a great resource for endocrinologists, physicians, general practitioners and researchers who are eager to understand the complex facets of endocrine hypertension.Endocri... hypertension is a term used to describe a group of endocrine pathologies that cause an elevation of blood pressure, estimated to account for up to 10% of all hypertension cases. Although common, this clinical condition is often overlooked. Patients with this condition are at risk of late diagnosis, delayed treatment and detrimental health consequences.
    • Data Science for Genomics

      • 1st Edition
      • November 27, 2022
      • Amit Kumar Tyagi + 1 more
      • English
      • Paperback
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      • eBook
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      Data Science for Genomics presents the foundational concepts of data science as they pertain to genomics, encompassing the process of inspecting, cleaning, transforming, and modeling data with the goal of discovering useful information, suggesting conclusions and supporting decision-making. Sections cover Data Science, Machine Learning, Deep Learning, data analysis, and visualization techniques. The authors then present the fundamentals of Genomics, Genetics, Transcriptomes and Proteomes as basic concepts of molecular biology, along with DNA and key features of the human genome, as well as the genomes of eukaryotes and prokaryotes. Techniques that are more specifically used for studying genomes are then described in the order in which they are used in a genome project, including methods for constructing genetic and physical maps. DNA sequencing methodology and the strategies used to assemble a contiguous genome sequence and methods for identifying genes in a genome sequence and determining the functions of those genes in the cell. Readers will learn how the information contained in the genome is released and made available to the cell, as well as methods centered on cloning and PCR.
    • Peptide and Peptidomimetic Therapeutics

      • 1st Edition
      • September 22, 2022
      • Nir Qvit + 1 more
      • English
      • Paperback
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      Peptide and Peptidomimetic Therapeutics: From Bench to Beside offers applied, evidence-based instruction on developing and applying peptide therapeutics in disease treatment, driving drug discovery, and improving patient care. Here, researchers, clinicians and students will find tools to harness the full power of peptides and peptidomimetics and improve bioavailability, stability, efficiency and selectivity of new therapeutics and their application in treatment plans. More than 20 leaders in the field share their approaches for identifying and advancing peptide and peptidomimetic therapeutics. Topics examined run from "bench to bedside," beginning with fundamental peptide science, protein-protein interactions and peptide synthesis. Later chapters examine modes for peptide drug delivery, including cell penetration peptide and peptidomimetic delivery, as well as the targeting of specific disease types, peptide therapeutics as applied to infectious disease, cancer, metabolic disorders, neurodegenerative disorders, and skin disorders, and antiparasitic and immunosuppressive peptidomimetics.
    • Diabetes Without Needles

      • 1st Edition
      • January 19, 2022
      • Artur Rydosz
      • English
      • Paperback
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      Diabetes Without Needles: Non-invasive Diagnostics and Health Management provides a comprehensive and objective compilation of the most promising noninvasive methods for glucose monitoring, including an in-depth analysis of their advantages and disadvantages in terms of biochemical processes. The latest advances in the field are discussed, including methods such as optical measurements, electrochemical measurements, exhaled breath analysis, direct measurements of glucose in the blood using noninvasive techniques, and the indirect analysis of biomarkers that are related to the glycemia. The book's author also presents recommendations for future research directions in this field. This book is a valuable resource for researchers in the areas of diabetes, noninvasive methods and diagnostics development.
    • Redox Chemistry and Biology of Thiols

      • 1st Edition
      • May 25, 2022
      • Beatriz Alvarez + 3 more
      • English
      • Paperback
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      Redox Chemistry and Biology of Thiols offers an applied, comprehensive overview of redox chemistry and biology of thiol-dependent processes. Running from basic biology and chemistry of redox phenomena to research methods and highlighting recently identified roles of thiols across cellular and bodily systems, this book draws upon a range of disciplines to illuminate new research directions, new applications of thiol studies, and clinical translation. Sections cover thiol oxidizing species, thiol reactivity and modifications, thioredoxin, glutaredoxin, glutathione, peroxidases, thiol repair enzymes, thiol oxidative signaling, disulfide bond formation, thiol-based redox biosensors, cysteine and hydrogen sulfide metabolism, iron-sulfur cluster biogenesis, thiols in chloroplasts, blood thiols, sugar and polyamine thiols in pathogenic organisms, redox medicine (therapeutic applications of thiols and drug development), as well as methods and bioinformatics tools.
    • The Chromosome 22q11.2 Deletion Syndrome

      • 1st Edition
      • August 19, 2022
      • Donna M. McDonald-McGinn
      • English
      • Paperback
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      The Chromosome 22q11.2 Deletion Syndrome: A Multidisciplinary Approach to Diagnosis and Treatment serves as the first comprehensive, user-friendly resource on the etiology, prognosis, and recurrence risk associated with the chromosome 22q11.2 deletion syndrome. Leading international contributors cover the background, genetics, testing methods, and pathophysiology of 22q11.2DS, placing emphasis on a strong foundation for multidisciplinary treatment strategies. Written by specialists in every applicable subspecialty, such as, cardiology, immunology, endocrinology, gastroenterology, hematology, ophthalmology, neurology, and psychiatry, among other fields. This book presents an authoritative resource with full color images that enhance concept illustration and aid in real-time decision-making. As 22q11.2 deletion syndrome has become a model for understanding rare and frequent anomalies, numerous medical issues, cognitive and behavioral phenotypes, and later onset conditions, this text will become the go to resource for clinicians, researchers, trainees, and motivated family members, in gaining a full understanding of this complex chromosomal disorder.
    • Transcultural Artificial Intelligence and Robotics in Health and Social Care

      • 1st Edition
      • April 22, 2022
      • Irena Papadopoulos + 3 more
      • English
      • Paperback
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      Transcultural Artificial Intelligence and Robotics in Health and Social Care provides healthcare professionals with a deeper understanding of the incredible opportunities brought by the emerging field of AI robotics. In addition, it provides robotic researchers with the point-of-view of healthcare professionals to understand what the healthcare sector – as well as the market – really needs from robotics technology. By doing so, the book fills an important gap between both fields in order to leverage new developments and collaborative work in favor of global patients. The book is aimed at the non-technical reader, especially health and social care professionals, and explains in a simple way the technological principles applied in the development of socially assistive humanoid AI robots (SAHR), the values which guide such developments, the ethics related to them, and research approaches in the field, with a focus on achieving a culturally competent SAHR.