Skip to main content

Elsevier Science

  • Endosomes and Lysosomes: A Dynamic Relationship

    • 1st Edition
    • Volume 1
    • B. Storrie + 1 more
    • English
    The intent in initiating this volume was to bring together a series of essays which would define our present understanding of the endosome and lysosome and their interrelationship. The editors deliberately encouraged the contributors to be speculative; to strive to put order to the "real" world of incomplete and sometimes conflicting data. Seeing science from the laboratory bench can often be like viewing an impressionistic painting from up close; a series of paint dabs with no apparent order. The contributors to this volume were asked to step back and leave the reader with a sense of the whole as well as the detail. To the extent that this has happened, the credit should go to the individual authors. Our understanding of endosomes and lysosomes has undergone a molecular revolution over the last decade. Hence, we now know much about the molecular features required for internalization of an endocytic receptor, or the function of mannose 6-phosphate receptors in the transport of lysosomal enzymes. We can trace and follow the flow of molecules. In this volume current molecular knowledge concerning the function and relationship of endosomes and lysosomes is presented. Because of this vast increase in knowledge of molecules, we have realized that endosomes in particular are very ephemeral organelles. In fact, endosomes may well not be discrete entities but rather continuously changing and evolving in their molecular composition. The dynamic nature of the relationship between endosomes and lysosomes is the unifying focus of the genetic, biochemical, microscopic, and molecular biological approaches described in the chapters which follow.
  • Advances in Developmental Biology

    • 1st Edition
    • Volume 2a
    • Paul Wassarman
    • English
    Advances in Developmental Biology was launched as a series by JAI Press in 1992 with the appearance of Volume 1. This series is inextricably linked to the companion series, Advances in Developmental Biochemistry, that was launched at the same time. As stated in the Preface to Volume 1: "Together the two series will provide annual reviews of research topics in developmental biology/biochemistry... written from the perspectives of leading investigators in these fields. It is intended that each review draw heavily form the author's own research contributions and perspective. Thus, the presentations are not necessarily encyclopedic in coverage, nor do they necessarily reflect all opposing views of the subject." Volume 2 of the series follows these same guidelines.
  • Chromatography of Mycotoxins

    Techniques and Applications
    • 1st Edition
    • Volume 54
    • V. Betina
    • English
    This work comprises two parts, Part A: Techniques and Part B: Applications. In Part A the most important principles of sample preparation, extraction, clean-up, and of established and prospective chromatographic techniques are discussed in relation to mycotoxins. In Part B the most important data, scattered in the literature, on thin-layer, liquid, and gas chromatography of mycotoxins have been compiled. Mycotoxins are mostly arranged according to families, such as aflatoxins, trichothecenes, lactones etc. Chromatography of individual important mycotoxins and multi-mycotoxin chromatographic analyses are also included. Applications are presented in three chapters devoted to thin-layer, liquid, and gas chromatography of mycotoxins.
  • Brain Theory

    Spatio-Temporal Aspects of Brain Function
    • 1st Edition
    • A. Aertsen
    • English
    Modern theories of brain function are increasingly concerned with dynamics. The task of organizing perception and behaviour in a meaningful interaction with the external world prompts the brain to recruit its various resources in a properly coordinated manner. Vis-a-vis the complexity and multitude of the dynamics involved, a careful orchestration of the various processing components, distributed over space and time, is essential. Hence, it should come as no surprise that a number of recent developments in both experimental and theoretical brain science have emphasized the aspect of spatio-temporal coordination. This collection of papers intends to capture these various developments in the brain sciences. It brings together new insights and concepts from various branches of experimental and theoretical neuroscience, partly in the form of review chapters, partly in short, focussed contributions, or critical essays. Further it sets out to explore the problems of the processing of the temporal dimension of sensory input and of the generation of space-time patterns in the motor output, as well as the intervening storage and transformation of temporal patterns in nerve nets.The publication is divided into four major sections: the first considers spatio-temporal aspects of brain function in the context of processing of sensory input and perception and the third, spatio-temporal aspects of brain function at the output end: planning and control of movement. The second section is dedicated to the intervening level of neuronal activity in the working brain and the various dynamics observed at different levels of resolution in space and time. The fourth part combines contributions that transcend this scheme.It is hoped the book achieves its goal which is to raise an interest in theoretical models that actively seek confrontation with experimental data from the functioning brain, and by a didactic effort aimed at experimentalists to present their data in a format that makes them more amenable to theory.
  • Neurobiology of Ischemic Brain Damage

    • 1st Edition
    • Volume 96
    • K. Kogure + 2 more
    • English
    In the eight years since the publication of Volume 63 of Progress in Brain Research, on this subject, developments in the research field have been very fast. For example, receptor physiology and pharmacology is now an intensively studied field, and the excitotoxic hypothesis of cell death is commonly accepted. Furthermore, it is recognized that ischemia and other insults give rise to a sustained depression of overall protein synthesis, yet lead to the expression of dormant genes and to synthesis of new proteins.In view of this development, this volume focusses on the cellular and molecular aspects of ischemic brain damage. The book will be of great value to all those interested in the pathophysiology of ischemic and traumatic brain damage.
  • Deep Ocean Circulation

    Physical and Chemical Aspects
    • 1st Edition
    • Volume 59
    • T. Teramoto
    • English
    This volume comprises the final report of the research project entitled the Dynamics of the Deep Ocean Circulation. The layered structure of the subsurface circulation, which had been predicted in the hypothetical model proposed prior to the research, is verified through Eulerian and Lagrangian measurements of current. By the use of the numerical model, the deep circulation of the Philippine Sea, which has been long supposed to be isolated from the North Pacific, is revealed to be derived in close association with that of the latter ocean. Behavior of the deep current around the equator is also clarified by numerical modeling. By the extensive use of sediment trapping technology, it becomes clear that sinking sediments play an important role in the distribution of chemical substances in the deep ocean. Graduate students in the field of oceanography will find this a good textbook.
  • Three-Dimensional Object Recognition Systems

    • 1st Edition
    • Volume 1
    • Anil K Jain + 1 more
    • English
    The design and construction of three-dimensional [3-D] object recognition systems has long occupied the attention of many computer vision researchers. The variety of systems that have been developed for this task is evidence both of its strong appeal to researchers and its applicability to modern manufacturing, industrial, military, and consumer environments. 3-D object recognition is of interest to scientists and engineers in several different disciplines due to both a desire to endow computers with robust visual capabilities, and the wide applications which would benefit from mature and robust vision systems. However, 3-D object recognition is a very complex problem, and few systems have been developed for actual production use; most existing systems have been developed for experimental use by researchers only. This edited collection of papers summarizes the state of the art in 3-D object recognition using examples of existing 3-D systems developed by leading researchers in the field. While most chapters describe a complete object recognition system, chapters on biological vision, sensing, and early processing are also included. The volume will serve as a valuable reference source for readers who are involved in implementing model-based object recognition systems, stimulating the cross-fertilisation of ideas in the various domains. The variety of topics on Image Communication is so broad that no one can be a specialist in all the topics, and the whole area is beyond the scope of a single volume, while the requirement of up to date information is ever increasing. This new closed-end book series is intended both as a comprehensive reference for those already active in the area of Image Communication, as well as providing newcomers with a foothold for commencing research. Each volume will comprise a state of the art work on the editor's/author's area of expertise, containing information until now scattered in many journals and proceedings.
  • Water Hammer in Pipe-Line Systems

    • 1st Edition
    • Volume 43
    • J. Záruba
    • English
    The physical principles of water hammer are explained in this volume. The basic mathematical methods of solution of water hammer and ways of limiting its effects are covered. Detailed description is given of the method of characteristics and the corresponding programs for personal computers, which enables solution of water hammer in a wide variety of hydraulic systems encountered in practice. Examples are given of solution of water hammer of common pipe-line systems as well as calculation of the steady state of flow, the determination of discharge through a pipe-line, measurements of characteristics of valves, pumps, turbines, determination of the operating régime of a valve in order to ensure a desired pressure and discharge curve, etc. This book will be of interest to those civil, mechanical and petroleum engineers dealing with the design and operation of hydraulic systems.
  • New Frontiers in Catalysis, Parts A-C

    • 1st Edition
    • Volume 75
    • L. Guczi + 2 more
    • English
    These volumes comprise the proceedings of the major international meeting on catalysis which is held at 4 year intervals. The programme focussed on New Frontiers in Catalysis including nontraditional catalytic materials and environmental catalysis. The contributions cover a wide range of fundamental, applied, industrial and engineering aspects of catalysis. The extensive range of highly efficient industrial techniques for observing and characterizing catalytically important surfaces is evident.The programme covered the following sessions: Mechanism, theory, in situ methods; Catalytic reaction on atomically clean surfaces; Catalytic reaction on zeolites and related substances; New methods and principles for catalyst preparation; Hydrotreatment reactions (HDS, HDN); Characterization of catalysts, application of novel techniques; Selective oxidation; New catalytic aspects of heteropoly acids and related compounds; Reaction of hydrocarbons; Nontraditional catalytic materials; Fuel upgrading; Alkane activation; Acid-base catalysis; New selective catalytic reactons, fine chemicals; Environmental catalysis; Industrial catalysis, deactivation, reactivation; Synthesis from syngas; Electrocatalysis; Photocatalysis.The invited lectures and 433 papers included in these volumes present an update on all areas of catalysis and applications.
  • Pulse Width Modulated (PWM) Power Supplies

    • 1st Edition
    • Volume 45
    • V. Quercioli
    • English
    A restricted source of power supply is analysed in this book - namely the switching mode power supplies (SMPS), which utilise the Pulse Width Modulation (PWM) technique to operate. Even though restricted, such a class of power supply is vital to circuits as most of modern electronic equipment is dependant on this form of technology to feed electronic boards. Its main advantages are greater efficiency, and its minimum physical size and weight.Interdiscipli... knowledge such as circuit theory, semiconductor devices theory and technology, magnetics theory and technology, linear and nonlinear control theory is involved in the design of an SMPS.This volume provides designers with an in-depth overview on the latest interdisciplinary methods involved in the design of switching mode power supplies, providing the reader with a tool whereby the learning time can be reduced and information about switching mode power supplies design processes can be easily accessed. The book adopts a systemic approach, subdividing the information into functional blocks whose properties and relationships are evaluated and compared with each other. A comprehensive list of references to the literature is given thus enabling the reader to follow up on more detail.