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Elsevier Science

  • Advances in Low-Temperature Biology

    • 1st Edition
    • Volume 3
    • P.L. Steponkus
    • English

  • Endocytosis and Exocytosis

    • 1st Edition
    • Volume 4
    • A.G. Lee
    • English
    Volume 4 of Biomembranes covers endocytosis, exocytosis and related processes. A major role of the plasma membrane is as a permeability barrier, keeping the inside of the cell inside and the outside, outside. Mechanisms must then exist to allow movement of material between the cell and its environment. One mechanism for export from the cell is by exocytosis, a process in which the membranes of secretory vesicles fuse with the plasma membrane releasing the contents of the vesicle into the extracellular medium. The process has been studied in particular depth for the release of neurotransmitters at the synapse. Import into the cell is possible by the process of receptor-mediated endocytosis in which selected plasma membrane proteins are internalizes; when these proteins are receptors for macromolecules, the result is uptake of the macromolecule. Transferring, the low-density lipoprotein, and asialoglycoproteins are all taken up into cells in this way. Phagocytosis, the ingestion of cells and cell fragments by neutrophils and macrophages, also involves receptors - on the phagocytic membrane - of which the best studied are those for the Fc domain of IgG, for the third component of complement, and for the mannose/fructose carbohydrates. Protection of a host against infection can also be achieved by damaging the integrity of the plasma membrane of the invading organism. This is the strategy evolved by the cytotoxic T lymphocytes, which produce a pore-forming toxin, perforin. Volume 4 of Biomembranes explores the structures and mechanisms involved in these biologically and medically important processes.

  • Chemical Factors in Neural Growth, Degeneration and Repair

    • 1st Edition
    • C. Bell
    • English
    This volume provides an up-to-date survey of current thinking concerning the actions of chemical factors in the regulation of neuronal behaviour under normal and pathological conditions. The book is divided into four sections, dealing with chemical factors involved with the formation of axon pathways, factors involved with neuronal survival and specialization during normal development, factors involved in normal maintenance and repair of adult neurons and, finally, factors that have been implicated as mediators of degenerative changes in neurological and neuropsychiatric disorders.

  • Quantification and Prediction of Hydrocarbon Resources

    • 1st Edition
    • Volume 6
    • A.G. Doré + 1 more
    • English
    The oil price shocks of the mid-1980s and their aftermath created radical changes in the petroleum industry, and underlined the need for reliable information on petroleum resources. Integration between the disciplines of petroleum geology, exploration geophysics, reservoir/petroleum engineering and economics became a necessity for resource management and strategic planning. This volume is designed to bring together some of the best techniques evolved to meet these challenges. The very broad scope of the volume, ranging from the macro (global) to micro (field and prospect) level, provides an overview of the thought processes currently prevalent in the industry and academia on the subject of resource quantification and prediction.This is one of the first books to cover the extensive assembly of hydrocarbon quantification and prediction techniques - of value to petroleum industry management, geoscientists, engineers and economists. Containing hundreds of illustrations, some in colour, the book is arranged in 26 chapters with a detailed subject index. Many service companies and university departments with links to the industry will also find much to interest them.

  • ATPases

    • 1st Edition
    • Volume 5
    • A.G. Lee
    • English
    Volume 5 of Biomembranes covers an important group of membrane proteins, the ATPases. The P-type ATPases couple the hydrolysis of ATP to the movement of ions across a membrane and are characterized by the formation of a phosphoyrlated intermediate. Included are the plasma membrane and muscle sarcoplasmic reticulum Ca2+ -ATPases, the (Na+ -K+) -ATPase, the gastric (H+ -K+) -ATPase, the plasma membrane H+ -ATPase of fungi and plants, the Mg2+ - transport ATPase, the Salmonella typhimurium, and the K+ -ATPase of Escherichia coli, KdpB. The other important classes of ATPase in eukaryotic systems are the vacuolar H+ -ATPases and the F0F1 ATP synthase, and, in bacteria, the anion-translocating ATPases, responsible for resistance to arsenicals and antimonials, and the (Na+ -Mg2+) -ATPase of Acholeplasma. Finally, eukaryotic systems contain a variety of ectonucleotidases important, for example, in hydrolysis of extracellular ATP released as a cotransmitter from cholinergic and adrenergic nerve terminals. Volume 5 of Biomembranes explores structure-function relationships for these mebrane-bound ATPases.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 19
    • English
    The very latest information on adverse drug effects from the international literature, compiled by an international team of experts.New reports are presented of adverse drug effects, critically analysed in context, in terms of clinical relevance and importance, and cross-referring to previous reports where necessary. New adverse effects are reported and evaluated, and previously reported adverse effects are re-evaluated in the light of the most recent information.Unique features:Reviews in which selected adverse effects are discussed in depth.Two separate indexes enhance the use of the book, allowing the reader to access information by drug name or by, adverse effects.

  • Design and Analysis of Experiments

    • 1st Edition
    • Volume 13
    • S. Ghosh
    • English

  • Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products

    • 1st Edition
    • Volume 19
    • M.M.W.B. Hendriks + 2 more
    • English
    In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given.Features of this book:• Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceutical technology and analytical chemistry• Illustrates the different approaches available to attain robustness• Gives ideas on how to use methods in practical situations.The book is intended for those who develop and optimize, and are responsible for the overall quality of, analytical methods and pharmaceutical technological products and procedures.

  • Statistical Methods in Finance

    • 1st Edition
    • Volume 14
    • Maddala
    • English
    A comprehensive reference work for teaching at graduate level and research in empirical finance. The chapters cover a wide range of statistical and probabilistic methods applied to a variety of financial methods and are written by internationally renowned experts.

  • Vertisols and Technologies for their Management

    • 1st Edition
    • Volume 24
    • N. Ahmad + 1 more
    • English
    Vertisols, one of the eleven established soil orders, are clay soils with unusual and interesting properties. They cover more than 350 million hectares of land in the world and in tropical Africa alone there are over 100 million hectares. Because of their very small particle size and high surface area, these soils have higher physical and chemical reactivity than other soils. Their interaction with agrochemicals/indust... wastes, has been, increasingly, the subject of research especially in the last two decades. Vertisols create special problems when used for engineering purposes.This book is intended to provide comprehensive and state-of-the-art information about Vertisols worldwide. Special attention is given to the use and management of soils such as fertilizer use, crop selection, soil tillage, water restriction on land including irrigation, and soil erosion. A special chapter has been added to deal with geotechnical engineering of Vertisols.Vertisols have great potential for agricultural production but many, especially in the developing world, are underutilized due to a lack of understanding regarding their behaviour and management.This book is written by leading scientists worldwide. It is expected that this monograph will be of great use to soil scientists and agronomists, graduate and senior graduate students.Improvement of their management may solve the current food deficiency in the world.

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