Skip to main content
Elsevier

Elsevier Science

  • Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products

    • 1st Edition
    • Volume 19
    • M.M.W.B. Hendriks + 2 more
    • English
    In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given.Features of this book:• Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceutical technology and analytical chemistry• Illustrates the different approaches available to attain robustness• Gives ideas on how to use methods in practical situations.The book is intended for those who develop and optimize, and are responsible for the overall quality of, analytical methods and pharmaceutical technological products and procedures.

  • Statistical Methods in Finance

    • 1st Edition
    • Volume 14
    • Maddala
    • English
    A comprehensive reference work for teaching at graduate level and research in empirical finance. The chapters cover a wide range of statistical and probabilistic methods applied to a variety of financial methods and are written by internationally renowned experts.

  • Design and Analysis of Experiments

    • 1st Edition
    • Volume 13
    • S. Ghosh
    • English

  • High Pressure Bioscience and Biotechnology

    • 1st Edition
    • Volume 13
    • Claude Balny + 1 more
    • English
    For many years, pressure was disregarded by biochemists. Today, there is a growing interest in pressure as a variable acting on biosystems.The activities that are currently of interest to scientists working in the field of High Pressure Bioscience and Biotechnology have been well presented in this volume, with topics ranging from physical biochemistry, microbiology, molecular biology and food science to industrial application.The editors have been successful in promoting the possibility of applying pressure in specific biotechnological areas, not only for food processing but also for biotechnology in general. These proceedings present an up-to-date view of high pressure research and will contribute to future developments in this field.

  • Physiological Functions of Cytochrome P450 in Relation to Structure and Regulation

    • 1st Edition
    • Volume 14
    • C.R. Jefcoate
    • English
    Research on the cytochrome P450 family of genes has traditionally been dominated by forms participating in drug metabolism. This has occurred in spite of early discovery of steroid hydroxy lase P450 cytochromes in the adrenal gland. More recently, contributions on the characterization and regulation of P450 cytochromes involved in biosynthetic reactions have been found at the international meetings on cytochrome P450 and in the several books on the field. Key recognition that P450 cytochromes should be recognized in a physiological context was provided by an international meeting in Jerusalem in 1991 and the subsequent publication of the proceedings in the Journal of Steroid Biochemistry and Molecular Biology (43, number 8, 92). Like this meeting, this book seeks to place equal weight on the physiological processes that are controlled by the products of reactions at usually very selective cytochrome P450 forms. Each of the authors was asked to discuss the molecular regulation of these P450 forms. Each of the authors was asked to discuss the molecular regulation of these P450 forms in the light of these physiological processes. In some cases the physiological role of the cytochrome P450 and even the natural substrate are unresolved, but a pattern of strong endocrine regulation is indicative of a hidden function. As more and more low abundance P450 genes are uncovered, the need to address potential physiological activities becomes more pressing. It is almost infinitely more difficult to identify a physiological substrate than to clone a new form.

  • Pectins and Pectinases

    • 1st Edition
    • Volume 14
    • J. Visser + 1 more
    • English
    Pectins are one of the classes of complex structural plant cell wall polysaccharides. They are localized in the middle lamella and primary cell wall of higher plants. Pectins have a long-standing use as gelling agents whereas their enzymatic degradation or modification plays an important role in the processing of agricultural crops and the manufacturing of foods and beverages. Progress in pectin and pectinase research has been most prominent in two areas over the past 5 years. The first one concerns the analysis and elucidation of the complex chemical structure of pectin and identification of novel enzymes involved in the degradation of these structures. The second area concerns the mode of action and the 3-dimensional structure of various pectin degrading enzymes as well as the cloning of a large number of genes encoding enzymes involved in pectin degradation and modification. This book covers the following topics. First the structural, physical and chemical properties of pectin are treated followed by information about its biosynthesis and about the biological effects of pectin and its degradation products in biological systems such as plant-pathogen interactions and human nutrition. Identification of novel enzymes, the mode of action of different pectinases and the 3-D structure of bacterial pectate lyases forms the second block. This is followed by the genetics and regulation of pectinase biosynthesis in saprophytic and phytopathogenic microbial systems as well as in plant systems. Finally, developments in pectin manufacturing and application of pectinases in traditional (food, beverage) and novel technologies are treated. This book is meant for those actively involved in fundamental and applied aspects of pectin and pectinase research but it is also of value for those interested in plant cell wall biosynthesis and architecture, phytopathology, food technology and human nutrition. This book not only reflects the present status of research in the field but it will turn out to be a very useful reference work as well.

  • NMR Spectroscopy and its Application to Biomedical Research

    • 1st Edition
    • S.K. Sarkar
    • English
    NMR has become the most diverse spectroscopic tool available to date in biomedical research. It is now routinely used to study biomolecular structure and dynamics particularly as a result of recent developments of a cascade of highly sophisticated multidimensional NMR pulse sequences, and of advances in genetic engineering to produce biomolecules, uniformly or selectively enriched with 13C, 15N and 2H.Features of this book:• Provides an up-to-date treatment of NMR techniques and their application to problems of biomedical interest• Most refined multidimensional pulse sequences including the basic aspects are covered by leading NMR spectroscopists.The book will be useful to NMR spectroscopists, biochemists, and to molecular biologists interested in the use of NMR techniques for solving biological problems.

  • Progress in Zeolite and Microporous Materials

    • 1st Edition
    • Volume 105
    • H. Chon + 2 more
    • English
    The proceedings of the 11th Zeolite Conference has been published in three volumes, containing 5 plenary lectures and 274 full papers. Part A comprises Synthesis and Characterization (99 papers), Part B Catalysis and Environment (102 papers) and Part C Adsorption and Diffusion, Modifications, Novel Materials and Theory (78 papers).Zeolite science and technology has been and continues to be an area receiving great attention. Increasing interest in the synthesis and the characterization of zeolite and microporous materials is reflected in the large number of contributions. Other areas gaining recognition include novel materials, adsorption, theory and modeling.

  • Hypothalamic Integration of Circadian Rhythms

    • 1st Edition
    • Volume 111
    • R.M. Buijs + 4 more
    • English
    The International Summer School of Brain Research, on which this book is based, was organized by the Netherlands Institute for Brain research (NIBR), which has a rich history dating back to the beginning of the century.The focus of interest in this present volume of Progress in Brain Research are the few thousand neurons at the base of the hypothalamus that form the biological clock. Attention is focused on the mechanisms underlying the generation of circadian rhythmicity within our biological clock, which is still far from understood. Contributions originating from many disciplines give updates on the latest theories on the molecular and electrophysiological basis of the pacemaker mechanism, and the various approaches used in different species. Attention is also paid to the way the signal of the biological clock is transferred to the rest of the central nervous system. New data on the role of the suprachiasmatic nucleus and its impact on the functioning of the human being is presented. Altogether an excellent volume which will further the understanding of this elusive material.

  • Semiconductor Nanoclusters - Physical, Chemical, and Catalytic Aspects

    • 1st Edition
    • Volume 103
    • P.V. Kamat + 1 more
    • English
    During the past decade there has been a phenomenal growth in the basic research of semiconductor nanoclusters and other nanomaterials. As the field has evolved the emphasis has shifted from basic theoretical description to field utilization of nanostructure-based devices. The topics of the various chapters presented in this book, written by leaders in the field, highlight the salient features of nanocrystalline semiconductor materials.Features of this book:- Provides synthetic strategies to generate ultrasmall particles, films and wires- Describes the characterization methodologies of a large number of nanomaterials from the molecular level to the long-range crystallographic ordering- Develops theoretical descriptions of present-day quantum confinement effects in various materials, including metallic particles, III-V semiconductors, and porous silicon- Explores the fate of photoinduced charge carriers in these materials and the phenomena of charge transfer across interfaces- Covers the utilization of these newly discovered effects in analytical chemistry, organic synthesis, environmental remediation, and electrochemistry.The aim of the book is to present the necessary background material for advanced undergraduate students in the field of physical chemistry and materials science and provide a reference book for the experts in this area.

Browse by Publisher