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Elsevier Science

  • Functionally Graded Materials 1996

    • 1st Edition
    • I. Shiota + 1 more
    • English
    Since a formulated concept of functionally graded materials (FGMs) was proposed in 1984 as a means of preparing thermal barrier materials, a coordinated research has been developed since 1986. The 125 papers presented here present state of the art research results and developments on FGM from the past decade.A wide spectra of topics are covered including design and modeling, fracture analysis, powder metallurgical processes, deposition and spray processes, reaction forming processes, novel processes, material evaluation for structural applications, organic and intelligent materials. Three reviews associated with national research programs on FGMs promoted in Japan and Germany, and the historical perspective of FGM research in Europe are presented as well.The resulting work is recommended to researchers, engineers and graduate school students in the fields of materials science and engineering, mechanical and medical engineering.

  • In VIVO Footprinting

    • 1st Edition
    • Volume 21
    • I.L. Cartwright
    • English
    The revolution in biological research initiated by the demonstration that particular DNA molecules could be isolated, recombined in novel ways, and conveniently replicated to high copy number in vivo for further study, that is, the recombinant DNA era, has spawned many additional advances, both methodological and intellectual, that have enhanced our understanding of cellular processes to an astonishing degree. As part of the subsequent outpouring of information, research exploring the mechanisms of gene regulation, both in prokaryotes and eukaryotes (but particularly the latter), has been particularly well represented. Although no one technical approach can be said to have brought the filed to its current level of sophistication, the ability to map the interactions of trans-acting factors with their DNA recognition sequences to a high level of precision has certainly been one of the more important advances. This "footprinting" approach has become almost ubiquitous in gene regulatory studies; however, it is in its "in vivo" application that ambiguities, confusions, and inconsistencies that may arise from a purely "in vitro"-based approach can often be resolved and placed in their proper perspective. Put more simply, that an interaction can be demonstrated to occur between purified factors and a particular piece of DNA in a test tube does not, of course, say anything regarding whether such interactions are occurring in vivo. The ability to probe for such interactions as they occur inside cells, with due attention paid to the relevant developmental stage, or to the tissue specificity of the interaction being probed, has made in vivo footprinting approach an invaluable adjunct to the "gene jockey's" arsenal of weapons.

  • SDL '97: Time for Testing

    SDL, MSC and Trends
    • 1st Edition
    • Ana Cavalli + 1 more
    • English
    As Cavalli and Sarma astutely remarked in the introduction to this volume, it is quite remarkable that SDL '97 may have the first participant younger than SDL itself. SDL '97 provides the opportunity to reflect the course SDL has taken and why it has been successful over two decades where other languages addressing the same market have failed.SDL now also has a permanent companion in MSC (Message Sequence Charts). MSC today is a language in its own right and has its areas of application both in conjunction with SDL and independently or in combination with other techniques. MSC has strong structuring concepts to specify message sequences for large systems and can be used to develop scenarios, which is extremely useful for test and design environments. The SDL Forum today really is the SDL and MSC Forum.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 34
    • English
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Freshwater and Estuarine Radioecology

    • 1st Edition
    • Volume 68
    • R.J. Blust + 5 more
    • English
    The Chernobyl accident drew attention to the difficulties of understanding the dynamics of radionuclide transport through the environment using older methods developed after the pseudo steady state pollution resulting after the weapons testing fallout. More recent approaches, which are reported in this book, have incorporated both the dynamic aspects highlighted by the pulse Chernobyl input and the importance of improvement in models that can be brought about by constraining parameters on the basis of a knowledge of the fundamental physics, chemistry, biology and ecology of the ecosystems involved. The papers within this volume include hydrodynamic models of suspended solids transport, ion exchange interpretation of radionuclide sorption: approaches applying a knowledge of membrane transport kinetics to the uptake of radionuclides by biota; the effects of different ecological niches on the relative uptake of radionuclides by different species; kinetic models of radionuclide uptake through trophic chains and the success and failure of different countermeasures attempted after the Chernobyl accident.

  • Time-Varying Image Processing and Moving Object Recognition, 4

    • 1st Edition
    • V. Cappellini
    • English
    New digital image processing and recognition methods, implementation techniques and advanced applications (television, remote sensing, biomedicine, traffic, inspection, robotics, etc.) are presented in this volume. Novel approaches (i.e. digital filters, source coding, neural networks etc.) for solving 2-D and 3-D problems are described. Many papers focus on the motion estimation and tracking recognition of moving objects. The increasingly important field of Cultural Heritage is also covered. Some papers are more theoretical or of review nature, while others contain new implementations and applications. Generally the book presents - for the above outlined area - the state of the art (theory, implementation, applications) with future trends.This book will be of interest not only to researchers, professors and students in university departments of engineering, communications, computers and automatic control, but also to engineers and managers of industries concerned with computer vision, manufacturing, automation, robotics and quality control.

  • Selected Topics in the History of Biochemistry. Personal Recollections. V

    • 1st Edition
    • Volume 40
    • G. Semenza + 1 more
    • English
    The Editors invited selected authors who had participated in or observed the explosive development of biochemistry and molecular biology particularly in the second half of this century to record their personal recollections of the times and circumstances in which they did their work. The authors were given a completely free rein with respect to both content and style and the editors have made no attempt to impose any sort of uniformity in the chapters. Each reflects the flavour of the personality of the author.The contributors to this volume encompass a wide variety of experiences in many different countries and in very different fields of biochemistry. Some have worked close to the laboratory bench throughout their scientific life and are continuing to do so. Others have been closely engaged in organisational matters, both nationally and internationally. All mention incidents in their own career or have observed those in others that will be of interest to future historians who will record and assess the period in which our contributors lived and worked. It was an extremely exciting time for life sciences.

  • Global Environmental Biotechnology

    • 1st Edition
    • Volume 66
    • D.L. Wise
    • English
    Environmental biotechnology is an emerging field of scientific and technological investigations that is truly global. Popular recognition is high for the environmental problems being faced and solved by biotechnology methods. This book presents selected papers from the 3rd International Symposium of the International Society for Environmental Biotechnology, held in Boston in July 1996. The following topics are covered: metals, mine drainage, removal and toxicity; waste treatment/monitoring... bioremediation; water quality; biodegradation; and local, national and international issues in biotechnology.

  • Elastohydrodynamics - '96

    Fundamentals and Applications in Lubrication and Traction
    • 1st Edition
    • Volume 32
    • C. Taylor + 7 more
    • English
    This volume represents the latest issue of a collection of Proceedings each dealing with a different topic in Tribology. This volume contains the Proceedings from the 23rd Leeds-Lyon Symposium which addressed the topic of Elastohydrodynamics and was attended by many international experts in the field.The Keynote Address was presented by Professor Stathis Ioannides on the subject of "Tribology in Rolling Element Bearings" and was followed by fifteen other sessions covering a wide variety of general areas from "Experimental" to "Lubricant Properties". In addition, nine other invited technical papers were presented to support the sessions.

  • Biotechnology Annual Review

    • 1st Edition
    • Volume 3
    • M.R. El-Gewely
    • English
    This new series aims at covering the development in the field of biotechnology in the form of comprehensive, illustrated and well-referenced reviews. With the expansion in the field of biotechnology both in industry as well as in education, coupled with the increase in the number of new journals reporting new results in the field, the need for a publication that is continuously providing reviews is urgent. The goal of Biotechnology Annual Review is to fill this gap. Reviewed topics will include biotechnology applications in medicine, agriculture, marine biology, industry, bioremediation and the environment. Fundamental problems dealing with enhancing the technical knowledge encountering biotechnology utilization, regardless of the field of application, will be emphasized. Other issues, dealing with policy and regulation of biotechnology as well as the problems of development in developing countries, as related to biotechnology, will be included in the various issues.The "Editorial Board" of Biotechnology Annual Review encourages suggestions and contributions of articles from industry or from academic institutions that would constitute a comprehensive covering of a relevant topic in biotechnology.Propos... for contributions and/or suggestions for topics for future volumes in this series should be sent to the Editor:Professor M. Raafat El-GewelyDepartment of BiotechnologyInstitu... of Medical BiologyUniversity of Tromsø9037 TromsøNorwayTel: (+47) 77 644654Fax: (+47) 77 645350

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