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Academic Press

  • Advances in Lipid Research

    Skin Lipids
    • 1st Edition
    • Volume 24
    • Peter M. Elias
    • English
    Advances in Lipid Research, Volume 24 provides information pertinent to the fundamental aspects of skin lipids. This book discusses the importance of epidermal lipids for cutaneous barrier function. Organized into 11 chapters, this volume begins with an overview of the biochemical, metabolic, and structural aspects of the role of lipids in permeability barrier formation and maintenance. This text then examines the lipid biophysics of the intercellular lipid domains in the stratum corneum, and the regulation of percutaneous absorption by these domains. Other chapters consider the lipid content and metabolism of cultured keratinocytes, which are grown under standard conditions and in various in vitro systems that attempt to produce an epidermal equivalent. This book discusses as well the important field of lipid signaling mechanisms in the epidermis. The final chapter deals with the clinical, pathophysiological, and therapeutic applications of vitamin D. This book is a valuable resource for chemist, cytochemists, and clinicians.
  • Current Topics in Bioenergetics

    Volume 6
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 6 provides information pertinent to the phenomenon of energy transduction. This book covers a wide variety of topics, including photosynthesis, muscle contraction, transport across membranes, and oxidative phosphorylation. Organized into six chapters, this volume begins with an overview of the solute transport functions of membrane vesicles from kidney and intestine. This text then examines the specialized calcium transport system of mitochondria from both mechanistic and biological viewpoints. Other chapters consider the energy-transducing mechanisms in bacteria and chromoplast from the standpoint of mechanism. This book discusses as well ionophores and channel formers as powerful tools in the study of membrane function. The final chapter deals with the metabolic link between fundamental cell physiological events, such as hormonal perturbation of metabolism and cell development, on the one hand, and an altered ability of mitochondria to transport Ca2+, on the other. This book is a valuable resource for bioenergeticists, biochemists, biologists, and microbiologists.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 10
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 10 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation. Organized into six chapters, this volume begins with an overview of the enzymes that exhibit half-of-the-sites activity. This text then examines the two different aspects of cyclic AMP-mediated systems. Other chapters consider the possible role of citrate synthase in the regulation of the citric acid cycle. This book discusses as well the regulation of the pentose phosphate pathway. The final chapter reviews the evidence for the occurrence of futile cycles at three control points in the metabolism of glucose, namely, at the level of glucose phosphorylation, at the interconversion of fructose mono- and biophosphates, and between pyruvate and phosphenol pyruvate. This book is a valuable resource for biochemists, biologists, and research workers.
  • Cannon's Point Plantation, 1794 - 1860

    Living Conditions and Status Patterns in the Old South
    • 1st Edition
    • John Solomon Otto
    • English
    Cannon's Point Plantation, 1794 – 1860: Living Conditions and Status Patterns in the Old South presents the results of historical archaeological investigations at Cannon's Point, an antebellum sea-island cotton plantation off the Georgia coast. This book compares investigations of archaeological remains at sites once occupied by slaves, overseers, and planters—people who differed in racial, social, and economic status. This text not only examines the material living conditions of the Old South, but also observes a substantial example of status patterning in the archaeological record. This publication is valuable to archaeologists and historians concerned with the treatment and daily lives of slaves in the Old South.
  • Microbial Iron Metabolism

    A Comprehensive Treatise
    • 1st Edition
    • J. B. Neilands
    • English
    Microbial Iron Metabolism: A Comprehensive Treatise provides a comprehensive treatment of microbial iron metabolism. It aims to contribute to an increased understanding of the path of iron in microbial species and, eventually, in the plant and animal. The book is organized into five parts. Part I describes some features of iron and its function in the microbial world. These include a historical sketch of the recognition of the importance of iron in cellular physiology; a description of certain physical properties of ferrous and ferric ions; and a list of various known biocoordination derivatives grouped by ligand atom. Metabolism under iron-limited conditions is also examined. Part II presents studies on iron transport, biosynthesis, and storage in microorganisms. Part III examines iron enzymes and proteins, including ferredoxin, rubredoxin, nitrogenase, and hydrogenase. Part IV deals with reactions of inorganic substrates. Part V presents a study on the role of bacterial iron metabolism in infection and immunity.
  • Cellular Automata

    • 1st Edition
    • E. F. Codd
    • Robert L. Ashenhurst
    • English
    Cellular Automata presents the fundamental principles of homogeneous cellular systems. This book discusses the possibility of biochemical computers with self-reproducing capability. Organized into eight chapters, this book begins with an overview of some theorems dealing with conditions under which universal computation and construction can be exhibited in cellular spaces. This text then presents a design for a machine embedded in a cellular space or a machine that can compute all computable functions and construct a replica of itself in any accessible and sufficiently large region of the space. Other chapters consider simulation of one cellular space by another. This book discusses as well the goal of exhibiting universal computer-constructor... The final chapter deals with the use of a digital computer for research in cellular automata. This book is a valuable resource for computer designers and programmers who want a better understanding of the principles of homogeneous cellular systems. Automata theoreticians and biochemists will also find this book useful.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 30
    • Bernard L. Horecker + 2 more
    • English
    Current Topics in Cellular Regulation: Volume 30 is a collection of papers that deals with eukaryotic DNA methylation, gene expression, regulation of nitrogenase activity, and the recognition of DNA by Type II restriction enzymes. Other papers discuss the mitochondrial Krebs cycle, enzyme mechanisms, transducin, and calcium-dependent cellular processes. One paper explains that methylation and demethylation of the DNA are complicated active processes, involving many aspects of the genome. The paper also notes that within the gross changes in methylation patterns, specific CpG sites play important roles in the expression or shutdown of target genes. Another paper concludes that, mono-ADP ribosylation being a mechanism of action of the diphtheria toxin, ADP ribosylation plays a role in normal cell metabolism by regulating the activity of key enzymes. One paper explains the significance of restriction enzymes into the nature of DNA-protein interactions; as well as the enzyme's possible role in discriminating between alternative DNA sequences. Biochemists, cellular researchers, micro-biologists, bio-physicists, and academicians involved in the study of cellular biology will find the collection very useful.
  • Prehistoric Subsistence on the Southern New England Coast

    The Records from Narragansett Bay
    • 1st Edition
    • David J. Bernstein
    • English
    Prehistoric Subsistence on the Southern New England Coast examines long-term trends in prehistoric subsistence in the Narragensett Bay region of Southern New England. The results suggest that, unlike other areas of Eastern north America, specialized agriculutral economies did not develop in this region prior to European contact. The book is accessible to both the general reader as well as scholars and students interested in consulting the original data for their own research and analysis.
  • Cell to Cell Signalling

    From Experiments to Theoretical Models
    • 1st Edition
    • A. Goldbeter
    • English
    Cell to Cell Signalling: From Experiments to Theoretical Models is a collection of papers from a NATO Workshop conducted in Belgium in September 1988. The book discusses nerve cells and neural networks involved in signal transfers. The works of Hodgkin and Huxley presents a prototypic combination between experimental and theoretical approaches. The book discusses the coupling process found between secretory cells that modify their behavior. The text also analyzes morphogenesis and development, and then emphasizes the pattern formation found in Drosophila and in the amphibian embryo. The text also cite examples of immunological modeling that is related to the dynamics of immune networks based on idiotypic regulation. One paper analyzes the immune dynamism of HIV infection. The text notes that hormone signaling can be attributed as responsible for intercellular communication. Another paper examines how the dominant follicle in the ovarian cycle is selected, as well as the effectiveness of hormone secretion responsible for encoding the frequency of occurrence of periodic signals. The book also discusses heart signal sources such as cardiac dynamics and the response of periodically excited cardiac cells. The text can prove valuable for practioners in the field of neurology and cardiovascular medicine, and for researchers in molecular biology and molecular chemistry.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 25
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation: Volume 25 is a collection of papers that deals with GTP, the central regulator of cellular anabolism, and the quantitative approach to metabolic control. , Other papers describe the inactivation and aldolases by limited proteolysis by lysosomal cathepsin M, the regulatory functions of proline, pyrroline-5-carboxyl... acid, as well as the characteristics of a hormonal regulation of amino acid transport. One paper suggests that GTP, possibly acting through high guanine nucleotide energy charge, acts to stimulate a wide variety of anabolic processes involved in cell growth or proliferation. Another paper proposes that lysosomes are responsible for the degradation of proteins and other macromolecules, and in regulating cytosolic enzymes. This action is due to the presence of selected proteinases (located on the outer lysosomal surface) that are active at neutral pH, and also which catalyze only limited proteolysis of cytosolic proteins. One paper describes the characteristics and hormonal regulation of a specific transport system for neutral amino acids, namely, the System A-mediated transport. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology.