The Alkaloids
Chemistry and Physiology
- 1st Edition - January 1, 1952
- Imprint: Academic Press
- Editors: R. H. F. Manske, H. L. Holmes
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 0 8 5 4 - 1
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 2 1 9 7 - 7
The Alkaloids: Chemistry and Physiology, Volume II focuses on strychnine and morphine alkaloids. This book discusses the elucidation of the structure of morphine, codeine, and the… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteThe Alkaloids: Chemistry and Physiology, Volume II focuses on strychnine and morphine alkaloids.
This book discusses the elucidation of the structure of morphine, codeine, and thebaine; synthetic hydrophenanthrenes related to the morphine alkaloids; and stereochemistry of the morphine alkaloids and sinomenine. The elucidation of the constitution of sinomenine, biological effects of colchicine, chemistry of individual alkaloids, and alkaloids of gelsemium species are also elaborated. This text likewise covers the isolation of the alkaloids, phenanthrene nucleus of morphine, fission around the nitrogen atom, and synthetic hydrophenanthrenes related to the morphine alkaloids.
This volume is useful to chemists and researchers conducting work on alkaloid chemistry.
Preface
The Morphine Alkaloids. I
I. Introduction
II. Elucidation of the Structure of Morphine, Codeine, and Thebaine
III. The Reactions of Morphine, Codeine, and Related Products
IV. The Reactions of Thebaine and Related Products
V. Synthetic Hydrophenanthrenes Related to the Morphine Alkaloids
VI. Table of Physical Constants
VII. References
The Morphine Alkaloids. II
I. Introduction
II. The Reactions of Morphine, Codeine and Neopine
III. The Reactions of Thebaine and Related Products
IV. The Stereochemistry of the Morphine Alkaloids and Sinomenine
V. Rearrangement and Elimination Reactions
VI. The Synthesis of Related Products
VII. Tables of Physical Constants
VIII. References
Sinomenine
I. Physiological Action, Isolation and Color Reactions
II. Elucidation of the Constitution of Sinomenine
III. Reactions of Sinomenine and Related Products
IV. Partial Synthesis of the Antipode of 1-Bromosinomeninone
V. Table of Physical Constants
VI. References
Colchicine
I. Chemistry of Colchicine
II. Biological Effects of Colchicine
III. References
Alkaloids of the Amaryllidaceae
I. Occurrence and General History
II. Chemistry of Individual Alkaloids
III. References
Acridine Alkaloids
I. Introduction
II. Degradation
III. Conclusion
IV. References
The Indole Alkaloids
I. Introduction
II. The Simple Bases
III. The Ergot Alkaloids
IV. The Alkaloids of Peganum harmala
V. Alkaloids of Evodia rutaecarpa
VI. The Alkaloids of Yohimbe
VII. The Quebracho Alkaloids
VIII. Alkaloids of Rauwolfia Species
IX. Alkaloids of Gelsemium Species
X. The Alkaloids of Calycanthaceae
XI. Alkaloids of Calabar Bean
XII. The Iboga Alkaloids
XIII. Alkaloids of Alstonia Species
XIV. Alkaloids of Geissospermum vellosii
XV. Quinamine and Cinchonamine
XVI. C-Dihydrotoxiferine-I
XVII. Tables
XVIII. References
The Erythrina Alkaloids
I. Introduction
II. Distribution
III. Isolation of the Alkaloids
IV. The Free Alkaloids
V. The Combined Alkaloids
VI. The Liberated Alkaloids
VII. Table of Physical Constants
VIII. References
The Strychnos Alkaloids. Part II
I. Introduction
II. Elucidation of the Structure of Strychnine and Brucine
III. Vomicine and Vomipyrine (425-436)
IV. The Structure and Stereochemistry of Strychnine
V. Tables of Physical Constants
VI. References
Author Index
Subject Index
Chapter VIII
Part I The Morphine Alkaloids. I
1. Introduction
II. Elucidation of the Structure of Morphine, Codeine, and Thebaine
1. The Phenanthrene Nucleus of Morphine
2. Oxazine and Isoquinoline Formulas for Morphine
3. Pyridine Formulas for Morphine
4. Transitional Formulas
5. The Camphane and Modern Formulas
6. Problems Remaining
III. The Reactions of Morphine, Codeine, and Related Products
1. Reduction
2. Oxidation
3. Substitution in the Benzene Nucleus
4. Fission around the Nitrogen Atom
5. The Action of Organometallic Compounds
6. The Codides and Morphides
7. The Desoxycodeines
IV. The Reactions of Thebaine and Related Products
1. Reduction
2. Oxidation
3. The Action of Organometallic Compounds
4. Fission Around the Nitrogen Atom
5. Rearrangements
V. Synthetic Hydrophenanthrenes Related to the Morphine Alkaloids
VI. Table of Physical Constants
VII. References
- Edition: 1
- Published: January 1, 1952
- No. of pages (eBook): 596
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9781483208541
- eBook ISBN: 9781483221977
RM
R. H. F. Manske
Affiliations and expertise
Dominion Rubber Research Laboratory, Guelph, OntarioHH
H. L. Holmes
Affiliations and expertise
University of British Columbia
Vancouver, Canada