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Academic Press

    • Apobec Enzymes

      • 1st Edition
      • Volume 713
      • April 21, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 7 8 6 6
      • eBook
        9 7 8 0 4 4 3 3 1 7 8 7 3
      Apobec Enzymes, Volume 713 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Fluorescent shift assay for APOBECs RNA editing, Low Error Sequencing Methods to Detect APOBEC-mediated RNA editing: Circular RNAseq and Safe-Sequencing System, "Safe-Barcode" RNAseq assay for APOBECs RNA editing, DT40 cell system to characterize somatic hypermutation, CH12 cell system to assay AID activity on class switch recombination, Purification of Enzymatically Active APOBEC Proteins from an Insect Cell Expression System, and more.Additional chapters cover Defining genome-wide mutagenic impact of APOBEC3 enzymes, APOBEC-induced mutational assay in yeast, Assays for APOBEC drug discovery, Biochemical assay for the identification of APOBECs inhibitors, An In Vitro Cytidine Deaminase Assay to Monitor APOBEC activity on DNA, Profiling rare C-to-U editing events via direct RNA sequencing, Global quantification of off-target activity by base editors, and so much more.
    • Navigating the Complexities of SARS-CoV-2 Immunobiology

      • 1st Edition
      • Volume 213
      • April 19, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 8 3 2 1
      • eBook
        9 7 8 0 4 4 3 2 3 8 3 3 8
      Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.
    • Current Topics in Developmental Biology

      • 1st Edition
      • Volume 162
      • April 18, 2025
      • English
      • Hardback
        9 7 8 0 3 2 3 9 1 2 4 1 9
      • eBook
        9 7 8 0 3 2 3 9 1 2 4 6 4
      Fertilization and Activation of Development, Volume 162 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.Chapters in this new release include Fertilization and the fast block to polyspermy in the African Clawed Frog, Xenopus laevis: A historical perspective, The Mammalian Egg's Zona Pellucida, Fertilization, and Fertility, Function, structure, and regulation of the broadly conserved gamete membrane fusion protein, HAP2, Gamete activation for fertilization and seed development in flowering plants, Paternal contributions to mammalian zygote, and much more.Additional sections cover Ovarian follicle formation and activation, Cytoskeletal dynamics in gamete (pro)nuclear migration across flowering plants, animals, and yeast, and Luteinizing hormone-induced changes in the structure of mammalian preovulatory follicles.
    • Translational Gastroenterology

      • 1st Edition
      • April 18, 2025
      • Adam E.M. Eltorai + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 4 2 6 8
      • eBook
        9 7 8 0 1 2 8 2 1 4 2 7 5
      Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.
    • Gender Affirming Vaginoplasty

      • 1st Edition
      • April 16, 2025
      • Gennaro Selvaggi + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 7 7 6 0
      • eBook
        9 7 8 0 4 4 3 2 1 7 7 7 7
      Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.
    • Whole Cell Biocatalysis

      • 1st Edition
      • April 16, 2025
      • Sergio Huerta-Ochoa + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 9 9 8 4
      • eBook
        9 7 8 0 4 4 3 2 3 9 9 9 1
      Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.
    • Medical Oncology Compendium

      • 1st Edition
      • April 16, 2025
      • Ramon Andrade B de Mello
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 6 0 9 0
      • eBook
        9 7 8 0 4 4 3 1 5 6 0 8 3
      Medical Oncology Compendium discusses several important topics in oncology with the help of leading experts worldwide who incorporate not only knowledge on recent developments in the field, but contextualize them within diverse socioeconomic environments to guarantee the applicability of the content in challenging scenarios. The book comprehensively discusses topics such as surgery, radiology, carcinogenesis, screening, assessment tools, evidence-based medicine, and precision oncology as applicable to different cancer types as non-small and small cell lung cancer, mesothelioma, breast cancer, gastric-rectal cancer, female specific cancers, prostate, skin and bone sarcomas.In addition, it discusses options to minimize oncology pain and palliative care. It is a valuable resource for oncologists, clinicians, researchers, healthcare workers and members of biomedical field who needs to understand more about diagnosis, treatment options and support for cancer patients.
    • Chest Blunt Trauma

      • 1st Edition
      • April 16, 2025
      • Piergiorgio Solli + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 8 6 6 9
      • eBook
        9 7 8 0 4 4 3 1 3 8 6 7 6
      Chest Blunt Trauma: A Modern Approach to a Multidisciplinary Disease provides novel treatment ideas for cardiothoracic injuries. The book interweaves knowledge of new surgical techniques, better understanding of patho-physiologic effects of injuries, and enhanced intensive care methods to create a holistic strategy of patient support. This text is a welcome addition for any clinician or researcher seeking refreshed information on the management of trauma to the chest wall.While non-operative treatment has long been the standard of care, the book discusses the vast improvements in understanding how to treat cardiothoracic injuries. Innovative surgical techniques, instruments, post-operative care, and the multisystemic nature of this illness.
    • Atlas of Marine Invertebrate Larvae

      • 2nd Edition
      • April 16, 2025
      • Michael J. Boyle + 2 more
      • English
      • Paperback
        9 7 8 0 0 8 1 0 2 8 7 1 1
      • eBook
        9 7 8 0 0 8 1 0 2 8 7 2 8
      Atlas of Marine Invertebrate Larvae, Second Edition covers the origins and history of marine larval science, contemporary state-of-the-art approaches to larval development and biology, and the highest-quality images and schematics showing the broadest diversity of marine larvae in the animal tree of life. This book illustrates larval body plans, the anatomy of their organ systems (muscular, sensory, digestive), including distinct ciliation patterns that facilitate swimming, and the complex metamorphic changes they undergo between different larval and growth stages. Each chapter contains in-text references that direct readers to both historical and contemporary research on the forms, functions, behaviors and biogeographical distributions of marine larvae.This book is a valuable and foundational resource for biologists across various disciplines, including biodiversity, biogeography, and developmental biology. Ecologists, taxonomists, oceanographers, and environmental scientists also benefit from the complete coverage of marine larval forms offered by this book. Additionally, the broad scope and phyletic coverage of marine biodiversity presented in this atlas is ideal for students in oceanography and marine biology, animal development, biological oceanography and invertebrate zoology.
    • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

      • 1st Edition
      • Volume 291
      • April 16, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 4 4 2 5 1
      • eBook
        9 7 8 0 4 4 3 3 4 4 2 6 8
      Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.