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Academic Press

  • Comprehensive Review of Lower Genital Neoplasms

    With Case Discussion
    • 1st Edition
    • Nadereh Behtash + 3 more
    • English
    Comprehensive Review of Lower Genital Neoplasms: With Case Discussion offers a practical, case-based guide to diagnosing and managing human papillomavirus (HPV)-related genital diseases. Designed for healthcare professionals, this resource simplifies complex concepts through engaging case presentations and high-quality colposcopy images, enhancing both visual learning and clinical skills.Comprehensive Review of Lower Genital Neoplasms: With Case Discussion offers a practical, case-based guide to diagnosing and managing human papillomavirus (HPV)-related genital diseases. Designed for healthcare professionals, this resource simplifies complex concepts through engaging case presentations and high-quality colposcopy images, enhancing both visual learning and clinical skills.This book bridges gaps in existing literature by combining evidence-based knowledge with hands-on teaching strategies, making it essential for clinicians to advance their expertise in HPV-related conditions.
  • Advances in Marine Biology

    • 1st Edition
    • Volume 103
    • English
    Advances in Marine Biology, Volume 103, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors.
  • The Microbiome and Cancer Treatment

    Overcoming Resistance and Enhancing Efficacy
    • 1st Edition
    • Sadhna Aggarwal + 3 more
    • English
    The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The book's chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance.Sect... also address the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters foster interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. Readers will benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.
  • Capsaicin, the Pungent Principle in Hot Pepper

    From Basic Pharmacology to Therapeutic Applications
    • 1st Edition
    • Arpad Szallasi
    • English
    Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.
  • Emerging Trends in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Emerging Trends in Cancer Research provides a comprehensive and up-to-date exploration of the latest advancements in cancer therapeutics, diagnostics, and intellectual property landscapes. Each chapter delves into the specific aspects of different cancers, offering insights into drug resistance mutations, biomarker trends, preclinical model updates, and clinical pipeline developments. The book also addresses the importance of diagnostics and the evolving landscape of intellectual property in cancer treatment. Sections analyze cancer drug resistance mutations, biomarker trends, and diagnostics across various cancers, including intestinal, cardiac, brain, and blood cancers.Readers will find coverage of clinical pipeline developments, intellectual property landscapes, and advancements in cancer therapeutics, diagnostics, and global drug delivery trends. This book is an invaluable resource for oncology, biomedical engineering, and pharmaceutical professionals, offering insights into the latest cancer research trends. It includes real-world case studies, practical applications, and discussions on regulatory and ethical considerations, making it essential for both seasoned researchers and graduate students.
  • Molecular Mechanisms of Spermatogenesis

    • 1st Edition
    • Volume 168
    • English
    Molecular Mechanisms of Spermatogenesis provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.
  • Chalcones

    From Drug Discovery to Pharmaceutical Applications
    • 1st Edition
    • Simone Carradori + 2 more
    • English
    Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.
  • Computer-Aided Drug Design in Modern Drug Discovery

    • 1st Edition
    • Yinuo Wu + 2 more
    • English
    Computer-Aided Drug Design in Modern Drug Discovery offers an in-depth exploration of CADD, featuring real-world case studies and practical examples that empower researchers to effectively harness this technology in drug discovery and development. Exploring the intricacies of CADD, the book comprises several key chapters, beginning with an introduction to its methods and evolution that is followed by a thorough examination of the integration of artificial intelligence in drug design. Subsequent chapters cover various CADD approaches, including ligand-based, structure-based, and fragment-based design, alongside AI-driven compound generation and drug screening.The book also showcases a selection of marketed drugs developed with CADD or AI, such as Captopril, Tirofiban, and Crizotinib, providing invaluable insights into the successes and challenges faced in real-world applications. Finally, the discussion of emerging trends and future directions in CADD and AI highlights the ongoing evolution of these methodologies and their integration with traditional drug development processes.
  • Ion Channels in Cellular Pathophysiology Part A

    • 1st Edition
    • Volume 97
    • English
    Ion Channels in Cellular Pathophysiology, Part A highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Modulation of ion channels by Group I metabotropic glutamate receptors, ATP-sensitive potassium channels in neurons: roles in and beyond metabolic control, Chemically induced cardiotoxicity: role of voltage dependent ion channels, Thyroid Hormone Deficiency-Induced Cardiac Ion Channel Dysfunction: Molecular Mechanisms and Arrhythmic Implications, and much more.Additional chapters discuss Pathophysiological Insights into Ion Channel Dysregulation and Electrical Remodeling in Cardiac Cells During Trypanosoma cruzi Infection, Targeting Sodium Channels in Neuroblastoma: Implications for Cellular Physiology, Breast cancer and voltage ion channels, Alpha-helical charged peptides a new concept of NaV gating modifiers, Nerve electrophysiological alterations in experimental diabetic neuropathy, and Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury.
  • Smart Wearable IoT

    Principles and Implementation of Development Modules with Wireless Biomedical SOC
    • 1st Edition
    • Shuenn-Yuh Lee + 1 more
    • English
    Smart Wearable IoT: Principles and Implementation of Development Modules with Wireless Biomedical SOC focuses on the development of intelligent wearable technology integrated with the Internet and various platforms. The book provides detailed guidance on building a user-friendly development platform that features intelligent wearable systems, including bio-signal SoCs/modules, user-friendly websites/apps, and artificial intelligence (AI) systems on edge/cloud. By exploring specific case studies, such as the ECG-based fatigue analysis system, readers will gain fundamental knowledge in biosignal acquisition and processing.This hands-on approach enables users to understand the integration of digital signal processing and artificial intelligence in analyzing physiological data, ultimately enhancing their skills in developing innovative wearable solutions.