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Academic Press

  • The Mammalian Mitochondrial Respiratory chain

    • 1st Edition
    • Walter Wainio
    • English
    The Mammalian Mitochondrial Respiratory Chain provides the vocabulary related to the mitochondrial respiratory chain in mammalian species. It explores the heterogeneous nature of mitochondria, the mammalian mitochondrial cytochromes, the concept of a respiratory chain for the oxidation of substrates, the cytochrome and non-cytochrome components of the chain, and the role of the respiratory chain in energy conservation. Organized into five chapters, this volume begins with an overview of the structure and composition of mitochondria in heart, liver, kidney, and brain before turning to the NADH oxidase system and its ability to generate one additional high-energy bond for every pair of electrons transferred compared to the succinate oxidase system. It also describes electron transfer in the respiratory chain and inhibitors of the respiratory chain such as antimycin A, along with differences in the pathways of electrons from succinate, choline, and NADH to oxygen as well as systems mediated by electron-transferrin... flavoprotein. The reader is also introduced to the processes involved in the fragmentation, extraction, and recombination of mitochondria; artificial electron acceptors such as phenazine methosulfate and artificial electron donors such as ascorbate and tetramethyl-p-phenyl... and the role of flavoproteins, including flavin mononucleotide and flavin adenine dinucleotide, in electron transport. The book concludes with a chapter that explains how the oxidation-reductions of the respiratory chain release energy in discrete packets. Graduate students and beginning researchers in biology will find this book extremely helpful.
  • Dinoflagellates

    • 1st Edition
    • David L. Spector
    • English
    The book begins with a general introduction and a taxonomic description of the dinoflagellates both to acquaint those unfamiliar with this group of organisms and to set the tone for the rest of the volume. It then addresses the following topics: cell biology (cell cortex, nuclear structure, cell cycle and mitosis, sexual reproduction, cysts and unusual inclusions); biochemistry (physiology and biochemistry, blooms and toxins, and biorhythms); and genetics. In addition, a comprehensive chapter on cell culturing provides the reader with an understanding of the growth conditions and requirements of various dinoflagellates and a simple to follow listing of culture media, all expressed in similar units for ease of comparison. The volume closes with a chapter on evolution which evaluates many of the features of dinoflagellates discussed in the text in terms of evolutionary significance.We hope that this treatise will be of use to research workers and students in the area of dinoflagellate biology and in other areas of biology in which dinoflagellates may be used as a model system for studying various biological problems.
  • Principles of Optical Fiber Measurements

    • 1st Edition
    • Dietrich Marcuse
    • English
    Principles of Optical Fiber Measurements focuses on the optical fiber systems, which are being added to the telephone networks of various countries around the world. This book explores the significance of optical fiber systems in the increasing variety of fiber-related products on the market. Comprised of seven chapters, this book starts with an overview of the fiber fabrication process with emphasis on the method of measurements to reduce fiber loss in the field of optical communication. This text then examines the special methods to measure extremely low dispersion in single-mode fibers. Other chapters consider the measurement requirements of commercial fiber manufacturers to allow them to specify their products as well as for fiber users to verify that they get what they expect. The final chapter deals with the various measurement methods for determining the V value of fibers as well as the geometrical dimensions of fibers and preforms. This book is a valuable resource for specialists and readers who desire a better understanding of fiber specifications.
  • Hazard Assessment of Chemicals

    Current Departments
    • 1st Edition
    • Jitendra Saxena
    • English
    Hazard Assessment of Chemicals: Current Developments, Volume 1 is a comprehensive and authoritative account of major developments in hazard assessment of chemicals. In addition to subject reviews, this volume contains case histories of topical chemicals and/or chemical classes in order to show examples of the applications of available methods and approaches for evaluating chemicals. Primary and secondary sources of information on chemicals are considered, along with the environmental and health hazards associated with chemicals. Comprised of 10 chapters, this volume begins with an assessment of information sources on toxic substances, followed by a discussion on pre-concentration of trace metals from aquatic environmental samples. Subsequent chapters focus on the reproductive toxicology of aquatic contaminants; partition coefficient and water solubility in environmental chemistry; in vitro metabolism and activation of chemical carcinogens; and modeling of toxic spills into waterways. Estimation of exposure to hazardous chemicals is also described, along with structure-activity relationships in hazard assessment. The final chapter presents a case study of azaarenes, with emphasis on their sources, distribution, environmental impact, and health effects. This book will be of interest to toxicologists, chemists, and environmental and public health officials.
  • Immunological Methods

    • 1st Edition
    • Bozzano G Luisa
    • English
    Immunological Methods, Volume II compiles procedures that are appropriate for studies in immunology. This book discusses the determination of equilibrium binding parameters of monoclonal antibodies specific for cell surface antigens; two-dimensional gel electrophoresis; and measurements of antibodies specific for DNA. The methods in surface physics for immunology; HLA-DR typing by complement-dependent B lymphocyte lysis; and protein A plaque assay for the detection of immunoglobulin-secre... cells are also elaborated. This text also covers the in vitro production and testing of antigen-induced mediators of helper T-cell function; limiting dilution analysis of precursors of cytotoxic T lymphocytes; and induction of antibody formation in mouse bone marrow. Other topics include the long-term culture and cloning of specific helper T cells; cloning of alloreactive T cells; and enzyme immunoassay for the detection of hybridoma products. This publication is valuable to immunologists and medical practitioners researching on immunological methods.
  • Intracellular Transport

    • 1st Edition
    • Katherine Brehme Warren
    • English
    Intracellular Transport, Volume 5 brings together a seemingly disparate group of scientists who offer their perspectives on the processes of and mechanisms underlying intracellular transport. Organized into 14 chapters, this volume begins with a review of some of the viewpoints about membrane structure and the unit membrane concept, including the so-called pauci-molecular theory of cell membrane structure advanced by Danielli and Davson. The next chapters focus on intracellular potentials, the localization of adenine nucleoside phosphatase activity, pinocytosis in amoeba, the brush border of cells, and the transport of gamma-aminobutyric acid. The reader is also introduced to pattern and rhythm; diffusion and reaction coupling; compartmental analysis and residence time distributions; and parametric pumping. The remaining chapters explore intracellular transport fluxes; theoretical aspects of permeability transport; rotating helices and contractile mechanisms; and the movements of cell membranes. This book is a valuable source of information for cellular biologists concerned with nature's evolved processing plants and engineers involved in the analysis and design of chemical processing plants.
  • Heat and Concentration Waves

    Analysis and Application
    • 1st Edition
    • G Turner
    • English
    Heat and Concentration Waves: Analysis and Applications describes the behavior of a limited class of waves of temperature or concentration that travels in a continuous medium, which itself is moving. This book is organized into nine chapters that discuss wave equations as solutions to linear differential equations. After briefly dealing with the fundamentals of waves and pulsed, this book goes on discussing the effect of introducing either an impulse or a steady source into a stream of uniform velocity or the so-called one-dimensional flow. The following chapters present some simplest basic equations for parameter determination in a flowing medium. These chapters also describe the pulses at an ideal boundary and the behavior of sine waves at such boundary, including the concept of reflections and the ease with which sine waves overcome the problems of incorporating boundary conditions into an experimental determination. This text further examines the behavior of reservoir phases under time-varying temperature or concentration. A chapter focuses on high-precision experimental measurements of sine waves. The concluding chapter outlines the computational processes, with emphasis on the estimation of experimental errors because of their effect on the reliability of parameter determination. Topics covered in the supplementary texts include the transformation of variables; the evaluation of important integrals; the normal distribution curve; aspects of the Laplace transform; some forms of transport equation common to both heat and mass transfer processes; and the interference of waves. This book will be of value to physical chemists, chemical and petroleum reservoir engineers, process metallurgists, physiologists, hydrologists, and soil scientists.
  • Radar Signals

    An Introduction to Theory and Application
    • 1st Edition
    • Charles Cook
    • English
    Radar Signals: An Introduction to Theory and Application introduces the reader to the basic theory and application of radar signals that are designated as large time-bandwidth or pulse-compression waveforms. Topics covered include matched filtering and pulse compression; optimum predetection processing; the radar ambiguity function; and the linear frequency modulation waveform and matched filter. Parameter estimation and discrete coded waveforms are also discussed, along with the effects of distortion on matched-filter signals. This book is comprised of 14 chapters and begins with an overview of the concepts and techniques of pulse compression matched filtering, with emphasis on coding source and decoding device. The discussion then turns to the derivation of the matched-filter properties in order to maximize the signal-to-noise ratio; analysis of radar ambiguity function using the principle of stationary phase; parameter estimation and the method of maximum likelihood; and measurement accuracies of matched-filter radar signals. Waveform design criteria for multiple and dense target environments are also considered. The final chapter describes a number of techniques for designing microwave dispersive delays. This monograph will be a useful resource for graduate students and practicing engineers in the field of radar system engineering.
  • Methods of Enzymatic Analysis

    • 1st Edition
    • Hans-UIrich Bergmeyer
    • English
    Methods of Enzymatic Analysis focuses on the general progress in enzymology and in the special field of enzymatic analysis. This book explores the commercial production of biochemical reagents for analysis and explains the transition from the possible use of enzymatic analysis to its various applications in pure and applied biochemistry. Organized into four sections, this book starts with an overview of the basis of enzymatic analysis and provides general experimental guidelines for the techniques of measurement and for the disintegration of cells and tissues. This text then provides detailed instructions for the determination of substrates and assay of enzyme activities. Other chapters explore the practical aspects and information necessary for the application of reagents to enzymatic analysis, including sources, stability, and purity required. The final section describes the commercially available enzymes, coenzymes, substrates, and several less common reagents. Biochemists, biophysicists, researchers, and graduate students will find this book extremely useful.
  • Trace Elements in Human and Animal Nutrition

    • 4th Edition
    • E Underwood
    • English
    Trace Elements in Human and Animal Nutrition, Fourth Edition, explores the physiological roles of trace elements in human and animal nutrition. It looks at the needs, tolerances, and interactions of trace elements with each other and with other nutrients and compounds, and it explores how deficient, toxic, or imbalanced intakes of such elements lead to biochemical and pathological changes. It also describes ways of diagnosing and addressing such aberrant intakes of trace elements, along with their principal sources. Organized into 20 chapters, this volume begins with an overview of the nature of trace elements and their mode of action, including iron, copper, molybdenum, cobalt, nickel, manganese, zinc, cadmium, chromium, iodine, selenium, fluorine, mercury, vanadium, silicon, lead, and arsenic. It then discusses the presence of these elements in animal tissues and fluids, along with their metabolism, functions, and toxicity. It also considers other elements, such as aluminum, antimony, barium, boron, bromine, germanium, lithium, rubidium, silver, strontium, tin, titanium, and zirconium. The book concludes with an analysis of the interrelationships among soil, plants, and animals. This book should be a valuable resource for students and chemists.