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Academic Press

  • Cell Growth and Cell Division

    • 1st Edition
    • R. J. C. Harris
    • English
    Cell Growth and Cell Division is a collection of papers dealing with the biochemical and cytological aspects of cell development and changes in bacterial, plant, and animal systems. One paper discusses studies on the nuclear and cytoplasmic growth of ten different strains of the genus Blepharisma, in which different types of nutrition at high and low temperatures alter the species to the extent that they became morphologically indistinguishable. The paper describes the onset of death at high and low temperatures as being preceded by a decrease in the size of the cytoplasm and a corresponding decrease in the size of the macronucleus. The moribund organisms, still possessing structure, are motionless with no distinguishable macronuclear materials. Another paper presents the response of meiotic and mitotic cells to azaguanine, chloramphenicol, ethionine, and 5-methyltryptophan. The paper describes the failure of spindle action, arrest of second division, inhibition of cytokinesis, aberrant wall synthesis, and alterations in chromosome morphology in meiosis cells. In the case of mitosis, a single enzyme—thymidine phosphorylase—shows that reagents which inhibit protein synthesis also inhibit the appearance of that enzyme if the reagent is applied one day before it normally appears. Other papers discuss control mechanisms for chromosome reproduction in the cell cycle, as well as the force of cleavage of the dividing sea urchin egg. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

  • Advances in Planar Lipid Bilayers and Liposomes

    • 1st Edition
    • Volume 20
    • English
    Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

  • The Interpretation of Ultrastructure

    • 1st Edition
    • R. J. C. Harris
    • English
    The Interpretation of Ulstrastructure is a collection of papers dealing with techniques in ulstrastructural research such as in fixation, reversed staining, ultrastructure in embryos and in plants, control of observations by light microscopy, and cytochemistry at the electron microscope level. One paper describes various fixatives used on rat liver tissue including a standard osmium tetroxide solution, pure melted osmium tetroxide, and strong osmium tetroxide solutions in carbon tetrachloride. Another paper points out that the use of electron micrographs of the cell nucleus and chromosomes should include approaches to chromosome analysis. For the investigator studying the three dimensional organization of chromosomes, his approaches should include classical cytology and cytogenetics, chemical and cytochemical studies on nuclei, as well as chemical and physical analysis of nucleic acid and nucleoprotein molecules. Several papers discuss the study of natural and artificial DNA-plasma by thin sections, an assessment of negative staining techniques for revealing ultrastructure, and other approaches in the study of biological ultrastructure by high-resolution electron microscopy. The collection will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.

  • Automorphic Forms and Geometry of Arithmetic Varieties

    • 1st Edition
    • K. Hashimoto + 1 more
    • English
    Automorphic Forms and Geometry of Arithmetic Varieties deals with the dimension formulas of various automorphic forms and the geometry of arithmetic varieties. The relation between two fundamental methods of obtaining dimension formulas (for cusp forms), the Selberg trace formula and the index theorem (Riemann-Roch's theorem and the Lefschetz fixed point formula), is examined. Comprised of 18 sections, this volume begins by discussing zeta functions associated with cones and their special values, followed by an analysis of cusps on Hilbert modular varieties and values of L-functions. The reader is then introduced to the dimension formula of Siegel modular forms; the graded rings of modular forms in several variables; and Selberg-Ihara's zeta function for p-adic discrete groups. Subsequent chapters focus on zeta functions of finite graphs and representations of p-adic groups; invariants and Hodge cycles; T-complexes and Ogata's zeta zero values; and the structure of the icosahedral modular group. This book will be a useful resource for mathematicians and students of mathematics.

  • Differentiation and Immunology

    Symposia of the International Society for Cell Biology, Vol. 7
    • 1st Edition
    • Katherine Brehme Warren
    • English
    Differentiation and Immunology is a collection of papers that deals with molecular specificity—the link between immunology and differentiation. One paper reviews the status of regulation in bacteria or viruses, and extends the results to animal cells. The paper also investigates a single aspect of the control of immunoglobulin through the use of plasmacytomas. Another paper discusses the role of macrophages in the minimum theory to possibly account for the energetics of the reaction with receptors, or to the frequency of antigen-sensitive cells. Some papers investigate the immunogenic function of macrophages, the transition from monocyte to macrophage, the factors influencing the formation of macrophage lysosomes, and the origin of macrophage lysosomes. Other papers also discuss the immune response as a model system for studies on cellular differentiation, as well as the differentiation for collagen synthesis in cultured cells. One paper suggests that in differentiation, the changes that can occur in the properties of protozoan cells, perpetuated for long periods, are reversible, and can be a means for survival—as every cell line is also capable of being a germ line. This collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunology research.

  • Analytic Properties of Automorphic L-Functions

    • 1st Edition
    • Volume 6
    • Stephen Gelbart + 1 more
    • J. Coates + 1 more
    • English
    Analytic Properties of Automorphic L-Functions is a three-chapter text that covers considerable research works on the automorphic L-functions attached by Langlands to reductive algebraic groups. Chapter I focuses on the analysis of Jacquet-Langlands methods and the Einstein series and Langlands’ so-called “Euler products”. This chapter explains how local and global zeta-integrals are used to prove the analytic continuation and functional equations of the automorphic L-functions attached to GL(2). Chapter II deals with the developments and refinements of the zeta-inetgrals for GL(n). Chapter III describes the results for the L-functions L (s, ?, r), which are considered in the constant terms of Einstein series for some quasisplit reductive group. This book will be of value to undergraduate and graduate mathematics students.

  • Huygens' Principle and Hyperbolic Equations

    • 1st Edition
    • Volume 5
    • Gunther Paul
    • J. Coates + 1 more
    • English
    Huygens' Principle and Hyperbolic Equations is devoted to certain mathematical aspects of wave propagation in curved space-times. The book aims to present special nontrivial Huygens' operators and to describe their individual properties and to characterize these examples of Huygens' operators within certain more or less comprehensive classes of general hyperbolic operators. The materials covered in the book include a treatment of the wave equation for p-forms over a space of constant sectional curvature, the Riesz distributions, the Euler-Poisson-Darbou... over a Riemannian manifold, and plane wave manifolds. Physicists will find the book invaluable.

  • Recent Topics in Differential and Analytic Geometry

    • 1st Edition
    • Volume 18
    • T. Ochiai
    • English
    Advanced Studies in Pure Mathematics, Volume 18-I: Recent Topics in Differential and Analytic Geometry presents the developments in the field of analytical and differential geometry. This book provides some generalities about bounded symmetric domains. Organized into two parts encompassing 12 chapters, this volume begins with an overview of harmonic mappings and holomorphic foliations. This text then discusses the global structures of a compact Kähler manifold that is locally decomposable as an isometric product of Ricci-positive, Ricci-negative, and Ricci-flat parts. Other chapters consider the most recognized non-standard examples of compact homogeneous Einstein manifolds constructed via Riemannian submersions. This book discusses as well the natural compactification of the moduli space of polarized Einstein–Kähler orbitfold with a given Hilbert polynomials. The final chapter deals with solving a degenerate Monge–Ampère equation by constructing a family of Einstein–Kähler metrics on the smooth part of minimal varieties of general kind. This book is a valuable resource for graduate students and pure mathematicians.

  • Drugs, Addiction, and the Brain

    • 1st Edition
    • George F. Koob + 2 more
    • English
    Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain.

  • Social Anxiety

    Clinical, Developmental, and Social Perspectives
    • 3rd Edition
    • Patricia M. DiBartolo + 1 more
    • English
    The third edition of Social Anxiety: Clinical, Developmental, and Social Perspectives integrates examinations of social anxiety, shyness, and embarrassment with the research on social anxiety disorder subtypes, biological theories and cognitive-behavioral or pharmacological treatment outcome studies.Clinicians, social and developmental psychologists and behavioral geneticists have all conducted research over the past ten years which is essential to furthering our understanding and treatment of social anxiety disorders. This book weaves together research findings gathered by renowned minds across these various disciplines, and deals with both theory and research. It explores what constitutes social anxiety, assesses the condition and its relationship to other psychological disorders, exploring the biological basis and treatment approaches as well. Coverage includes key issues not discussed fully by other books, including related disorders in adults and children, relationship to social competence and assertiveness, perfectionism, social skills deficit hypothesis, comparison between pharmacological and psychosocial treatments, and potential mediators of change in the treatment of social anxiety disorder.From the Author: Although social anxiety disorder (social phobia) is widely researched topic in psychiatry, other disciplines, such as social and developmental psychology, have independently been studying the same phenomena for many years. Yet, there has been very little cross-discipline communication and integration. The main objective of the book is to integrate the findings on social anxiety from various disciplines, including clinical psychology, psychiatry, social psychology, neuroscience, and developmental psychology.

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