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Elsevier

Academic Press

  • Enhancing the Control of Systems and Devices

    Improving Performance, Reliability and Adaptability in Dynamic Environments
    • 1st Edition
    • Sheetla Prasad + 2 more
    • English
    Enhancing the Control of Systems and Devices: Improving Performance, Reliability and Adaptability in Dynamic Environments provides an in-depth exploration of the application of sophisticated control design strategies to enhance the control of systems and devices in terms of performance, reliability, and adaptability in dynamic environments. A sophisticated control design strategy refers to the use of advanced and intricate control techniques to achieve specific objectives in complex systems.

  • Fruit Seeds and Peels for Sustainable Biomaterials

    • 1st Edition
    • Sneh Punia Bangar + 1 more
    • English
    Fruit Seeds and Peels for Sustainable Biomaterials explores the utilization of fruit and vegetable waste in the production of bioplastics as environmentally friendly alternatives to conventional petroleum-based plastics. The book presents innovative approaches to reducing the carbon footprint of the packaging industry while advancing principles of recyclability, sustainability, and the circular economy.The chapters provide an in-depth examination of various waste valorization techniques and compile global research efforts focused on the transformation of various fruit processing by-products. These industrial wastes are rich in polysaccharides, such as cellulose, hemicellulose, and lignin, which can be further treated to synthesize nanocellulose crystals or fibers using different physicochemical and nonconventional methods.The book highlights the application of these biomaterials in packaging, offering food professionals and other stakeholders sustainable alternatives to traditional plastic polymers. It delivers comprehensive insights into the potential of fruit seeds as a renewable source of biomaterials, and presents valuable scientific information on the technologies involved in using bio-based materials for food preservation. These insights aim to reduce the use of non-biodegradable plastic packaging materials.

  • An Introduction to the Finite Element Method with the Variational Approach

    • 1st Edition
    • Prakash Mahadeo Dixit + 1 more
    • English
    An Introduction to the Finite Element Method with the Variational Approach offers a comprehensive solution to the gaps often found in introductory texts on the Finite Element Method (FEM). The book provides a thorough introduction to the fundamental principles of linear and time-independent FEM within the variational framework. It meticulously covers the derivation of 1-D FEM equations based on variational functionals, encompassing both linear and higher-order elements, and shape functions driven by convergence criteria. Furthermore, it explores 1-D numerical integration, outlines coding procedures, and provides insights into handling material nonlinearity and time-dependent scenarios.Expanding into 2-D problems, the book offers derivations of 2-D FEM equations tailored to diverse engineering disciplines, including Steady-State Heat Conduction, Solid Mechanics (covering torsion, plane strain/axisymmetric cases, and the bending, stability, and vibrations of thin plates), as well as Fluid Mechanics (addressing incompressible inviscid and viscous fluids). It includes detailed discussions on element continuity, numerical integration techniques, and even includes 2-D codes for selected problems. The book concludes by delving into recent advancements in FEM, with a specific focus on applications in machine learning and isogeometric analysis.

  • Targeting DNA Repair Mechanisms, Tumor Genetics, and Signaling Pathways

    Synergistic Approaches in Gastrointestinal Cancer Treatment
    • 1st Edition
    • Ganji Purnachandra Nagaraju + 1 more
    • English
    Targeting DNA Repair Mechanisms, Tumor Genetics, and Signaling Pathways: Synergistic Approaches in Gastrointestinal Cancer Treatment provides a comprehensive exploration of the complex mechanisms underlying gastrointestinal (GI) cancers, including colorectal, gastric, liver, and pancreatic malignancies. The book addresses the urgent need for innovative therapeutic strategies by synthesizing current research on DNA repair, tumor genetics, and cellular signaling pathways critical to cancer progression and treatment. It examines the roles of DNA repair mechanisms and the influence of genetic factors on personalized medicine while also discussing the potential of combining targeted therapies to enhance treatment efficacy.Featuring real-world case studies and insights from leading experts, the book bridges the gap between basic research and clinical application. For an academic audience, this resource promotes a holistic understanding of GI cancer biology, addresses treatment resistance, and fosters collaboration among researchers and clinicians, ultimately improving patient outcomes in this rapidly evolving field.

  • Computational Approaches to Natural Products Discovery

    • 1st Edition
    • Volume 730
    • English
    Computational Approaches to Natural Products Discovery, Volume 720 provides descriptions of the latest techniques in computational methods for the study of natural products. Techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Chapters in this new release cover Prediction of natural product bioactivity from BGC sequence to guide genome mining efforts, Genome mining for resistance genes to identify bioactive natural products with ARTS, Predicting lasso peptide structure with LassoPred, Predicting lanthipeptide structure with Rosetta, Using lsaBGC to investigate BGC Evolution, and an Analysis of BGC evolution with CORASON.

  • Advances in Immunology

    • 1st Edition
    • Volume 168
    • English
    Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.

  • Stochastic Analysis and Control in Energy, Environmental and Resource Management Applications

    • 1st Edition
    • Hidekazu Yoshioka + 1 more
    • English
    Stochastic Control in Energy, Environmental and Resource Management Applications offers practical insights and solutions to contemporary challenges in resource, environment, and energy management. From sustainable fishery practices to water quality assessment and renewable energy generation, the book addresses urgent global issues. Additionally, it delves into the mathematical and computational aspects of stochastic control, aligning with modern concepts like Sustainable Development Goals and Green Transformation. It bridges the gap between experimentalists, who face practical issues without strong theoretical foundations, and theoreticians, who often propose idealized solutions. It does so by using stochastic modeling and control theory to foster balance between the environment and humanity.

  • Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer

    • 1st Edition
    • Volume 207
    • English
    Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer, Volume 207 covers the latest techniques and strategies used to investigate and boost cytotoxic activity in cells targeting cancer. Chapters include An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol, New protocol to measure mitochondria polarization/functio... at the immunological synapse, Analysis of CAR-T cell–mediated cytotoxicity in solid tumor models, Investigation of the in vitro lytic capacity of CAR-T by microscopyal, Antigen-specific T cell cytotoxicity toward target tumor cells, In vitro expansion of stem-like memory T cells via D-mannose supplementation, and much more.Additional chapters explore High-throughput time-lapse imaging of B16 target cell killing by ovalbumin-specific CD8+ T cells, Evaluation of an intracellular magneto-mechanical approach for regulating dendritic cell activation, Analyzing the effect of NK cells on in-vivo models of tumor dissemination by digital pathology and flow cytometry, Super-resolution imaging of the NK cell synapse on supported lipid bilayers using MINFLUX nanoscopy, ASSESSMENT OF NK CELL CYTOTOXICITY INDUCED BY IL-15 BASED IMMUNOTHERAPY AGAINST CANCER CELLS, Combined phenotyping and functional analysis of isolated human natural killer cells using spectral flow cytometry, and much more.

  • Advances in Virus Research

    • 1st Edition
    • Volume 124
    • English
    Advances in Virus Research, Volume 124 in this ongoing seriesseries, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Emerging and Reemerging Viral Threats to Pregnancy and Nomenclature for vertically transmitted plant.

  • Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies

    • 1st Edition
    • Shuvomoy Banerjee + 1 more
    • English
    Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies addresses the critical challenge of cancer chemoresistance, synthesizing insights from cancer biology, molecular biology, biotechnology, and nanotechnology. The book explores the complex mechanisms underlying drug resistance, including alterations in key signaling pathways and the tumor microenvironment's role in cancer cell survival. It highlights advancements in drug delivery technologies, such as nanomedicine and biomimetic strategies, which enhance drug targeting and minimize off-target effects. The integration of techniques like CRISPR-Cas9 and artificial intelligence in developing next-generation therapies is also emphasized.For an academic audience, this book serves as an essential resource to foster interdisciplinary collaboration in cancer research. It equips researchers, clinicians, and industry professionals with the knowledge needed to navigate the evolving landscape of cancer therapeutics, addressing critical challenges in drug delivery and chemoresistance to improve patient outcomes.

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