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  • Reactivity of P-H Group of Phosphorus Based Compounds

    • 1st Edition
    • Kolio D. Troev
    • English
    Reactivity of P-H Group of Phosphorus Based Compounds bridges the gap between inorganic and organic phosphorus compounds, providing a basis to explore the myriad possibilities for synthesis of novel low and high molecular phosphorus-containin... compounds. It covers well-documented reactions in detail, including: tautomerization, oxidation, reduction, alkylation, oxidation coupling, addition reaction to: carbon-carbon multiple bonds, Schiff base, isocyanates, nitriles, epoxides; addition to carbonyl group, Kabachnik- Fields reaction, cross-coupling reaction and more. In an accessible style complete with synthetic routes and figures, the resource then covers the reactivity of multiple P-H group members: phosphines, phosphine oxides, hypophosphorus acid, H-phosphinic acids and polys(alkylene H-phosphonate). This valuable coverage supports the advancement of research and applications in this area for scientists solving a scientific problem or starting a variety of new projects, such as a new reaction for the synthesis of biologically active compounds, new methods of polymer synthesis or a new methodology for polymer modification.

  • Data Literacy

    How to Make Your Experiments Robust and Reproducible
    • 1st Edition
    • Neil Smalheiser
    • English
    Data Literacy: How to Make Your Experiments Robust and Reproducible provides an overview of basic concepts and skills in handling data, which are common to diverse areas of science. Readers will get a good grasp of the steps involved in carrying out a scientific study and will understand some of the factors that make a study robust and reproducible.The book covers several major modules such as experimental design, data cleansing and preparation, statistical analysis, data management, and reporting. No specialized knowledge of statistics or computer programming is needed to fully understand the concepts presented. This book is a valuable source for biomedical and health sciences graduate students andresearchers, in general, who are interested in handling data to make their research reproducibleand more efficient.

  • The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine

    • 1st Edition
    • Uri Galili
    • English
    The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.

  • miRNA and Cancer

    • 1st Edition
    • Volume 135
    • English
    miRNA and Cancer, Volume 135, the latest volume in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, and includes specific chapters on Non-coding RNAs as Biomarkers of Cancer, The Enigma of microRNA Regulation in Cancer, Animal Models to Study microRNA functions, Non-coding RNAs and Cancer, microRNAs in Cancer Susceptibility, ts-RNAs versus microRNAs, microRNAs and AML, and microRNAs and Epigenetics.

  • Northeast Pacific Shark Biology, Research and Conservation Part A

    • 1st Edition
    • Volume 77
    • English
    Northeast Pacific Shark Biology, Research and Conservation, Part A, Volume 77 highlights the biological attributes of, and the conservation efforts targeted at, populations of vulnerable sharks in the Northeastern Pacific Ocean bordering the west coast of the United States, one of the most economically and ecologically important oceanic regions in the world. Updates in this new volume include chapters on Biodiversity, Conservation and Life History of Northeastern Pacific Chondrichthyans, a Review of current genetic analyses of Northeast Pacific sharks and conservation implications, and a section on the Trophodynamics and ecological impacts of eastern North Pacific sharks.

  • Genetically Engineered Foods

    • 1st Edition
    • Volume 6
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Genetically Engineered Foods, Volume 6 in the Handbook of Food Bioengineering series, is a solid reference for researchers and professionals needing information on genetically engineered foods in human and animal diets. The volume discusses awareness, benefits vs. disadvantages, regulations and techniques used to obtain, test and detect genetically modified plants and animals. An essential resource offering informed perspectives on the potential implications of genetically engineered foods for humans and society. Written by a team of scientific experts who share the latest advances to help further more evidence-based research and educate scientists, academics and government professionals about the safety of the global food supply.

  • The Clinician's Guide to Cognitive-Behavioral Therapy for Childhood Obsessive-Compulsive Disorder

    • 1st Edition
    • Eric A. Storch + 2 more
    • English
    The Clinician's Guide to Cognitive-Behavioral Therapy for Childhood Obsessive-Compulsive Disorder brings together a wealth of experts on pediatric and adolescent OCD, providing novel cognitive behavioral strategies and considerations that therapists can immediately put into practice. The book provides case studies and example metaphors on how to explain exposure models to children in a developmentally appropriate manner. The book also instructs clinicians on how to use symptom information and rating scales to develop an appropriate exposure hierarchy. The book is arranged into two major sections: assessment and treatment of childhood OCD and special considerations in treating childhood OCD. Each chapter is structured to include relevant background and empirical support for the topic at hand, practical discussion of the nature and implementation of the core component (such as exposure and response prevention, cognitive therapy, psychoeducation and more), and a case illustration that highlights the use of a particular technique.

  • Fe-S Cluster Enzymes Part A

    • 1st Edition
    • Volume 595
    • English
    Fe-S Cluster Enzymes, Part A, Volume 595 is the first of two volumes focused on Fe-S cluster enzymes. New topics of note in this series include Electrochemistry of Fe/S Proteins, Genetic, biochemical and biophysical methods for studying Fe-S proteins and their assembly, Fluorescent reporters to track Fe-S cluster assembly and transfer reactions, Mechanism-based strategies for structural characterization of radical SAM reaction intermediates, Purification and Characterization of Recalcitrant Cobalamin-Dependent Radical S-adenosylmethionine Methylases, A polymerase with potential: the Fe-S cluster in Human DNA Primase, In Vitro Studies of Cellular Iron-sulfur Cluster Biosynthesis, Trafficking and Transport, and Fe-S cluster Hsp70 Chaperones: the ATPase cycle and protein interactions.

  • Immunity and Inflammation in Health and Disease

    Emerging Roles of Nutraceuticals and Functional Foods in Immune Support
    • 1st Edition
    • Shampa Chatterjee + 2 more
    • English
    Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here.

  • OQAM/FBMC for Future Wireless Communications

    Principles, Technologies and Applications
    • 1st Edition
    • Tao Jiang + 3 more
    • English
    OQAM/FBMC for Future Wireless Communications: Principles, Technologies and Applications　introdu... the concepts and key technologies of OQAM/FBMC, which has been regarded as the potential physical layer technique in future wireless communication systems. It comprises 10 chapters that provide an overview of wireless communications, introduce wireless channels, single carrier and multicarrier modulations, and three types of FBMC systems, also comparing OQAM/FBMC with OFDM. Other chapters introduce the OQAM/FBMC communication system model, the FFT implementation, CP insertion, PSD analysis, prototype filter optimization, joint PAPR reduction and sidelobe suppression, overhead reduction with virtual symbols, time and frequency domain channel estimations, block-wise SFBC for MIMO OQAM/FBMC, and much more.

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