Morphological Mouse Phenotyping
Anatomy, Histology and Imaging
- 1st Edition - January 27, 2017
- Authors: Jesus Ruberte, Ana Carretero, Marc Navarro
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 2 8 0 5 - 3
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 2 9 7 2 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 2 8 7 7 - 0
Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology… Read more
Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology.
Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man.
- Features more than 2,200 original images showing the anatomy, histology, and cellular structure of mouse organs
- Includes images specifically produced for this book in the Mouse Imaging Platform (Center for Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona)
- Offers an integrative vision of mouse morphology using correlative X-ray, computed tomography, magnetic resonance, and ultrasound images
- Employs classical anatomical techniques such as conventional dissection, skeletal preparations, vascular injections, and histological, immunohistochemical, and electron microscopy techniques to characterize mouse morphology
Scientists working with mice; laboratory animal vets
1: Introduction
Origin of the Laboratory Mouse
Anatomical Nomenclature
2: Osteology
Bones of the Skull and Mandible
Vertebral Column and Thorax
Bones of the Thoracic Limbs
Bones of the Pelvic Limbs
3: Arthrology
Joints without Articular Cavity
Joints with Articular Cavity
4: Myology
Form and Structure of Muscles
The Skeletal Muscle Fiber
Comparative Anatomy of Mouse Musculature
5: Digestive tract
Oral Cavity
Pharynx and Esophagus
Stomach
Intestine
Liver
6: Respiratory apparatus
Nasal Cavity
Larynx
Trachea
Lungs
7: Urinary organs
Kidneys
Ureter
Urinary Bladder
Urethra
8: Male genital organs
Testicles and Epididymis
Accessory Genital Glands
Penis
9: Female genital organs
Ovaries
Uterine Tubes
Uterus
Vagina
Vulva and Clitoris
10: Anatomy of development
Ontogenic Development
Placenta
11: Circulatory System
Heart
Arteries
Veins
Lymphatic System
Blood and Lymph
12: The endocrine glands
Pancreas
Adrenal Gland
Thyroid Glands
Parathyroid Gland
Hypophysis
13: Nervous System
Central Nervous System
Peripheral Nervous System
14: Eye and related structures
Eyelids and Lacrimal System
Eyeball
Orbit
15: Vestibulocochlear organ
External Ear
Middle Ear
Internal Ear
16: Common integument
Skin
Modified Skin Structures
- Edition: 1
- Published: January 27, 2017
- Language: English
JR
Jesus Ruberte
Jesus Ruberte is Head of the Mouse Imaging Platform in the Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autonoma de Barcelona, Spain.
Affiliations and expertise
Head of the Mouse Imaging Platform, Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autonoma de Barcelona, SpainAC
Ana Carretero
Ana Carretero works with the Mouse Imaging Platform in the Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autònoma de Barcelona, Spain.
Affiliations and expertise
Mouse Imaging Platform, Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Veterinary School, Universitat Autònoma de Barcelona, SpainMN
Marc Navarro
Affiliations and expertise
Mouse Imaging Platform, Center for Animal Biotechnology and Gene Therapy, Department of Animal Health and Anatomy, Universitat Autonoma de Barcelona, SpainRead Morphological Mouse Phenotyping on ScienceDirect