Part I: Overview Health and Aging
Chapter 1. Impact of Nutrition on Healthy Aging
- Abstract
- Introduction
- Dietary Fiber
- GI and Gut Microbiota
- The Role of SCFAs in Health and Disease
- Ongoing and Future Directions
- References
Chapter 2. Aging and the Recovery of Skin Function and Appearance
- Abstract
- Introduction
- Skin Aging
- Diet and Skin Aging
- The Mediterranean Diet
- References
Chapter 3. Changes in Nutritional Needs With Aging
- Abstract
- Introduction
- Age-Related Changes Affect Nutrition
- Changes in Nutritional Needs
- Using Supplements
- Assessing Nutritional Status
- Conclusion
- References
Chapter 4. Sugars, Glucocorticoids, and the Hypothalamic Controls of Appetite
- Abstract
- Overview
- The Lipogenesis Hypothesis
- Sugar Solutions and the Hypothalamus
- Sugars and the Hypothalamus: Evidence from Humans
- Conclusions and Summary
- References
Chapter 5. Appetite Regulation in Healthy Aging
- Abstract
- Introduction
- Reduced Appetite and Energy Intake During Aging
- Less Suppression of Appetite and Energy Intake in Older People
- Gastrointestinal Regulation of Appetite and Energy Intake
- Appetite Regulation in Healthy Older Subjects
- Appetite Regulation in Malnourished Older Subjects
- Loss of Body Weight During Aging
- Loss of Muscle Mass During Aging
- Conclusion
- References
Chapter 6. Human Microbiome and Aging
- Abstract
- Introduction
- Human Microbiome
- Microbiome Through the Human Life Cycle
- Microbiome and the Immune Response
- Impact of Diet on Microbiota
- Therapeutic Interventions for Microbial Manipulation
- Implications for Health and Disease
- Irritable Bowel Syndrome
- Anxiety and Depression
- Conclusion
- Acknowledgment
- References
Chapter 7. Fibromyalgia Syndrome: Role of Obesity and Nutrients
- Abstract
- Introduction
- Pathophysiology of Fibromyalgia
- Fibromyalgia and Obesity
- Symptoms of FMS and Obesity
- Role of Diet and Micronutrients in Fibromyalgia
- Summary
- References
Chapter 8. Aging and Gait
- Abstract
- Introduction
- Mechanics of Changes in Gait
- Changes in Body Structure and Physiological Functions
- Conclusion
- References
Chapter 9. Assessment of Nutritional Status in the Elderly
- Abstract
- Introduction
- Medical History With a Particular Emphasis on the Nutritional History and Physical Examination
- Anthropometric Tests
- Biochemical Tests
- Survey Methods
- Conclusion
- References
Chapter 10. Eating Capability Assessments in Elderly Populations
- Abstract
- Introduction
- Eating Capability: Definition and Constituents
- Hand Force Assessments
- Actions in the Oral Cavity: Mastication and Swallowing
- Tongue Capability Assessment
- Swallowing Capability Assessment
- Assessing Sensing Capability
- The Eating Capability Concept in Use
- Conclusions
- References
Part II: Nutrients (Vitamins and Minerals) in Health in Aging Adults
Chapter 11. Healthy Food Choice and Dietary Behavior in the Elderly
- Abstract
- Why Do We Eat What We Eat?
- Determinants of Dietary Behavior
- Design and Methods
- Discussion and Applications
- References
Chapter 12. Vitamin D and Diabetes in Elderly People
- Abstract
- Introduction
- Potential Mechanisms and Pathways for an Effect of Vitamin D in Diabetes
- Epidemiological Evidence of Hypovitaminosis D as a Risk Factor for Diabetes
- Vitamin D and Diabetes in the Elderly
- Conclusions
- References
Chapter 13. Vitamin D and the Elderly Orthopedic Patient
- Abstract
- Introduction
- Vitamin D
- References
Chapter 14. Vitamins and Minerals in Older Adults: Causes, Diagnosis, and Treatment of Deficiency
- Abstract
- Introduction
- Needs
- Causes of Deficiency
- Diagnosis of Deficiency
- Treatment
- Conclusion
- References
Chapter 15. The Role of B Group Vitamins and Choline in Cognition and Brain Aging
- Abstract
- Introduction
- Role of B Group Vitamins and Choline in Normal Brain Functioning and Neuroprotection
- The Homocysteine Cycle: Biochemistry and Clinical Implications
- Conclusions
- References
Chapter 16. Vitamin B12 Deficiency in the Elderly
- Abstract
- Introduction
- Vitamin B12 Absorption
- Vitamin B12 Metabolism and Function
- Causes of Vitamin B12 Deficiency in the Elderly
- Clinical Manifestations of Vitamin B12 Deficiency
- Diagnosis of Vitamin B12 Deficiency
- Vitamin B12 Deficiencies in the Institutionalized Elderly
- Therapeutic Management
- Screening for Vitamin B12 Deficiency in the Elderly
- References
Chapter 17. Vitamin E Isoform-Specific Functions in Allergic Inflammation and Asthma
- Abstract
- Introduction
- Vitamin E Isoforms, Sources, and Functions
- Asthma and Allergic Lung Inflammation
- Clinical Studies of Asthma and Tocopherol Isoforms
- Comparing Tocopherol Doses in Humans and Preclinical Mouse Studies
- Alpha-Tocopherol and Gamma-Tocopherol Regulate Allergic Inflammation and Airway Hyper-Responsiveness in Preclinical Adult Animal Studies
- Tocopherol Regulation of Leukocyte Recruitment
- Maternal Tocopherols and Offspring Development of Allergy
- Alpha-Tocopherol and Gamma-Tocopherol: Opposing Functions in Other Chronic Inflammatory Diseases
- Conclusions
- References
Part III: Dietary Supplements and Herbs, Functional Foods, in Health in Aging Adults
Chapter 18. Polyphenols and Intestinal Health
- Abstract
- Introduction
- Role of Gut Microbiota in Intestinal and Systemic Health
- Classes, Subclasses, Examples, and Sources of Dietary Polyphenols
- Antioxidant and Antiinflammatory Properties of Polyphenols
- Influence of Polyphenols on Macro- and Micronutrient Bioavailability
- Polyphenol Digestion, Absorption, and Utilization
- Polyphenol–Microbe Interactions
- Intestinal Health Benefits of Polyphenols
- Conclusions and Implications
- References
Chapter 19. Nootropics, Functional Foods, and Dietary Patterns for Prevention of Cognitive Decline
- Abstract
- Introduction
- Dietary Patterns and Complete Nutritional Plans With Cognitive Implications
- Micronutrients With Possible Effects on Cognition
- Foods, Herbs, Spices, and Dietary Complements With Functional Properties in Terms of Neuroprotection and Possible Cognitive Enhancement
- Medical Foods
- Conclusions
- References
Chapter 20. Chalcones Target the Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) Signaling Pathway for Cancer Chemoprevention
- Abstract
- Introduction
- Characteristics of TRAIL and Apoptosis Induced by TRAIL
- Characteristics of Chalcones
- Chalcone Potential for Enhancing TRAIL-Mediated Apoptosis in Cancer Cells
- References
Chapter 21. Anti-inflammatory Dietary Ingredients, Medicinal Plants, and Herbs Exert Beneficial Health Effects in Aging
- Abstract
- Introduction
- Renal Function
- Cognitive Function
- Conclusion
- Conflict of Interest
- References
Chapter 22. Calorie Restriction Mimetics From Functional Foods: Impact on Promoting a Healthy Life Span
- Abstract
- Introduction: Calorie Restriction
- CRMS in Mediating Metabolic Pathways of Calorie Restriction
- Targeting SIRT-1 for CRM Discovery and Development
- Concluding Remarks and Perspectives
- References
Chapter 23. Nutraceuticals for Healthy Skin Aging
- Abstract
- Introduction
- Oxidative Stress
- Beta-Carotene
- Biotin
- Coenzyme Q10 or Ubiquinone
- Citrulline–Arginine
- Isoflavone Soy Beans
- L-carnosine
- Lycopene
- Lutein
- Melatonin
- Omega-3
- Polyphenols
- Prebiotics
- Probiotics
- Selenium
- Silicon
- Vitamin C
- Vitamin E
- Zinc
- Conclusions
- References
- Further Reading
Chapter 24. Effects of Resveratrol on Cognitive Functions
- Abstract
- Introduction
- Background: Sources and Pharmacokinetics of Resveratrol
- Animal Studies
- Human Studies
- Mechanisms
- Limitations and Challenges for Future Studies
- Conclusion
- References
Chapter 25. North American Natural Health Products and Sexual Function in Aging Adults
- Abstract
- Introduction
- Kingdom Animalia
- Kingdom Plantae
- Kingdom Bacteria
- Kingdom Fungi
- Kingdom Protista
- Discussion
- Acknowledgments
- References
Part IV: Protein and Energy in Health and Growth of Elderly
Chapter 26. Physiological Aspects of Coenzyme Q10 in Plasma in Relationship with Exercise and Aging
- Abstract
- Overview
- Do Levels of CoQ Decrease During Aging?
- Importance of CoQ in the Prevention of Cardiovascular Disease
- CoQ10 Levels Can Be Modified by Physical Activity and Lifestyle
- Plasma CoQ10 and Obesity
- Regulation of CoQ10 Levels in Plasma
- Effect of Statins on CoQ10 Levels
- Concluding Remarks
- Acknowledgments
- References
Chapter 27. Cellular and Physiological Effects of Arginine in Seniors
- Abstract
- Introduction
- Sources of Arginine
- Biochemistry of Arginine
- Arginine Physiology and Biological Importance
- Arginine Dosing and Supplementation
- References
Chapter 28. Late-Onset Caloric Restriction Alters Skeletal Muscle Metabolism: Mechanisms from Animal and Human Studies
- Abstract
- Skeletal Muscle Metabolism
- Skeletal Muscle Metabolism Changes with Aging
- Impacts of the Age-Related Changes in Skeletal Muscle Metabolism
- Mechanisms of Age-Related Changes in Skeletal Muscle Metabolism
- Caloric Restriction Alters Skeletal Muscle Metabolism
- Mechanisms of the CR-Induced Alteration in Skeletal Muscle Metabolism
- Conclusion
- References
Chapter 29. Healthy Foods for Healthy Aging: The Case for Protein
- Abstract
- Recommendations: An Instruction Manual for Eating to Achieve Healthy Aging
- Dietary Protein: The Foundation of a Healthy Body and Healthy Aging
- Milk: A Natural Functional Food for a Strong and Healthy Body
- Eggs: A Nutritious Food with Big Health Benefits
- Seafood: Powerful Help for Healthy Aging
- Meat and Poultry: A Juicy Issue
- Food Choices for the Elderly: Are These Good for Healthy Aging?
- Social Influences, Values, Attitudes, and Meat: Behind the Scenes of Food Choices
- Culture, Perceptions of Food Choices, and Eating Habits: Perception Is Reality
- The Mediterranean Diet: Fast-Food Advice
- Conclusions
- References