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  • Accelerated Predictive Stability (APS)

    Fundamentals and Pharmaceutical Industry Practices
    • 1st Edition
    • Fenghe Qiu + 1 more
    • English
    Accelerated Predictive Stability (APS): Fundamentals and Pharmaceutical Industry Practices provides coverage of both the fundamental principles and pharmaceutical industry applications of the APS approach. Fundamental chapters explain the scientific basis of the APS approach, while case study chapters from many innovative pharmaceutical companies provide a thorough overview of the current status of APS applications in the pharmaceutical industry. In addition, up-to-date experiences in utilizing APS data for regulatory submissions in many regions and countries highlight the potential of APS in support of registration stability testing for certain regulatory submissions. This book provides high level strategies for the successful implementation of APS in a pharmaceutical company. It offers scientists and regulators a comprehensive resource on how the pharmaceutical industry can enhance their understanding of a product’s stability and predict drug expiry more accurately and quickly.

  • Advances in Agronomy

    • 1st Edition
    • Volume 150
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 150, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Sustainable Use of Chemicals in Agriculture

    • 1st Edition
    • Volume 2
    • English
    Sustainable Use of Chemicals in Agriculture, Volume 2, explores the wide breadth of emerging and state-of-the-art technologies used to study the sustainable use of chemicals in agriculture. Sections in this new release include modern agriculture in Europe and the role/place of chemicals, a regulatory vision of the sustainable use of pesticides and risk mitigation, the perception of the concept in other regions of the globe, certification and added value for farm production, and how research and education can influence implementation and development, among other valuable topics.

  • Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome

    • 1st Edition
    • Shruti Mishra + 2 more
    • English
    Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome helps readers identify and select the specific genes causing oncogenes. The book also addresses the validation of the selected genes using various classification techniques and performance metrics, making it a valuable source for cancer researchers, bioinformaticians, and researchers from diverse fields interested in applying systems biology approaches to their studies.

  • Advances in Parasitology

    • 1st Edition
    • Volume 100
    • English
    Advances in Parasitology, Volume 100, the latest in a series first published in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on Human Parasitology and Parasitic Diseases: Heading Towards 2050, Environmental aspects, Structural and Physical Properties of Schistosome Eggs, and Interventions against parasitic diseases to safeguard childhood development.

  • Diagnostic and Therapeutic Applications of Exosomes in Cancer

    • 1st Edition
    • Mansoor M. Amiji + 1 more
    • English
    Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.

  • Made in Africa

    Hominin Explorations and the Australian Skeletal Evidence
    • 1st Edition
    • Steve Webb
    • English
    Made in Africa: Hominin Explorations and the Australian Skeletal Evidence describes and documents the largest collection of modern human remains in the world from its time period. These Australian fossils, which represent modern humans at the end of their great 20,000 km journey from Africa, may be reburied in the next two years at the request of the Aboriginal community. Part one of the book provides an overview of modern humans, their ancestors, and their journeys, explores the construct of human evolution over the last two and half million years, and defines the background to the first hominins and later modern humans to leave Africa, cross the world and meet other archaic peoples who had also travelled and undergone similar evolutionary pathways. Part two focuses on Australia and the evidence for its earliest people. The Willandra Lakes fossils represent the earliest arrivals and are the largest and most diverse late Pleistocene collection from this part of the world. Although twenty to twenty-five thousand years younger than the oldest archaeological site in Australia, they exemplify the migrating end-point of the human story that reflect a diversity and culture not recorded elsewhere in the world. Part three records the Willandra Lake Collection itself from a photographic and descriptive perspective. Evolutionary biologists and geneticists will find this book to be a valuable documentation of the 20,000 km hominid migration from Africa to the most distant parts of the world, and of the challenges and findings of the Willandra Lake Collection.

  • Advances in Immunology

    • 1st Edition
    • Volume 138
    • English
    Advances in Immunology, Volume 138, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including chapters on Eosinophil Development, Disease Involvement, and Therapeutic Suppression, Immunoglobulin A responses to the microbiota, Unexpected roles for intracellular complement in the regulation of TH1 responses, Magnesium in T cell signaling, and immunological synapse and T cell signaling.

  • Neurobiology of Abnormal Emotion and Motivated Behaviors

    Integrating Animal and Human Research
    • 1st Edition
    • Susan Sangha + 1 more
    • English
    Neurobiology of Abnormal Emotion and Motivated Behaviors: Integrating Animal and Human Research pulls together world-renowned leaders from both animal and human research, providing a conceptual framework on how neuroscience can inform our understanding of emotion and motivation, while also outlining methodological commonalities between animal and human neuroscience research, with an emphasis on experimental design, physiological recording techniques and outcome measures. Typically, researchers investigating the neurobiology of emotions focus on either animal models or humans. This book brings the two disciplines together to share information and collaborate on future experimental techniques, physiological measures and clinical outcomes.

  • Control of Power Electronic Converters and Systems

    Volume 2
    • 1st Edition
    • Frede Blaabjerg
    • English
    Control of Power Electronic Converters, Volume Two gives the theory behind power electronic converter control and discusses the operation, modelling and control of basic converters. The main components of power electronics systems that produce a desired effect (energy conversion, robot motion, etc.) by controlling system variables (voltages and currents) are thoroughly covered. Both small (mobile phones, computer power supplies) and very large systems (trains, wind turbines, high voltage power lines) and their power ranges, from the Watt to the Gigawatt, are presented and explored. Users will find a focused resource on how to apply innovative control techniques for power converters and drives.

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