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  • Modeling Evolution of Heterogeneous Populations

    Theory and Applications
    • 1st Edition
    • Irina Kareva + 1 more
    • English
    Modeling Evolution of Heterogeneous Populations: Theory and Applications describes, develops and provides applications of a method that allows incorporating population heterogeneity into systems of ordinary and discrete differential equations without significantly increasing system dimensionality. The method additionally allows making use of results of bifurcation analysis performed on simplified homogeneous systems, thereby building on the existing body of tools and knowledge and expanding applicability and predictive power of many mathematical models.

  • Neuroprotection in Autism, Schizophrenia and Alzheimer's disease

    • 1st Edition
    • Illana Gozes + 1 more
    • English
    Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry. Sections discuss the shared pathophysiological mechanisms that underlie autism, schizophrenia/mood disorders and Alzheimer’s disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders.

  • Molecular Nutrition: Carbohydrates

    • 1st Edition
    • Vinood B. Patel
    • English
    Molecular Nutrition: Carbohydrates presents the nutritional and molecular aspects of carbohydrates. As part of the Molecular Nutrition includes sections covering carbohydrate metabolism, carbohydrates in the diet, insulin resistance, dietary sugars, cardiometabolic risk, lipoproteins, low-carbohydrate diets, antioxidants, refined dietary sugars, fats, glucose transporters, glucose sensing, the role of phosphorylation, carbohydrate responsive binding protein, cyclic AMP, peroxisome proliferator-activat... receptors, SIRT1, insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes rRNA and transcription, and more. In addition, the book addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health.

  • Optical Fiber Telecommunications VII

    • 1st Edition
    • Alan Willner
    • English
    With optical fiber telecommunications firmly entrenched in the global information infrastructure, a key question for the future is how deeply will optical communications penetrate and complement other forms of communication (e.g., wireless access, on-premises networks, interconnects, and satellites). Optical Fiber Telecommunications, the seventh edition of the classic series that has chronicled the progress in the research and development of lightwave communications since 1979, examines present and future opportunities by presenting the latest advances on key topics such as: Fiber and 5G-wireless access networks Inter- and intra-data center communications Free-space and quantum communication links Another key issue is the use of advanced photonics manufacturing and electronic signal processing to lower the cost of services and increase the system performance. To address this, the book covers: Foundry and software capabilities for widespread user access to photonic integrated circuits Nano- and microphotonic components Advanced and nonconventional data modulation formats The traditional emphasis of achieving higher data rates and longer transmission distances are also addressed through chapters on space-division-multi... undersea cable systems, and efficient reconfigurable networking. This book is intended as an ideal reference suitable for university and industry researchers, graduate students, optical systems implementers, network operators, managers, and investors. Quotes: "This book series, which owes much of its distinguished history to the late Drs. Kaminow and Li, describes hot and growing applied　topics, which include long-distance　and wideband systems,　data centers, 5G, wireless networks, foundry production of photonic integrated circuits, quantum communications, and　AI/deep-learning... These subjects will be highly beneficial for industrial R&D　engineers, university teachers and　students, and funding　agents in the business sector." Prof. Kenichi IgaPresident (Retired), Tokyo Institute of Technology 　 "With the passing of two luminaries, Ivan　Kaminow and Tingye Li, I feared the　loss of one of the premier reference books in the field. Happily, this new version comes to chronicle the current　state-of-the... and is　written by the next　generation of leaders. This is a must-have reference book for anyone　working in or trying to understand　the field of optical fiber communications　techn... Donald B. Keck Vice President, Corning, Inc. (Retired) 　 "This book is the seventh edition in the definitive series that was previously marshaled by the extraordinary Ivan Kaminow and Tingye Li, both sadly no longer with us.　　The series has charted the　remarkable progress made in the field, and over a billion kilometers of optical fiber currently snake across the globe carrying ever-increasing Internet traffic.　Anyone wondering　about how we will cope with this incredible growth must read this book." Prof. Sir David Payne Director, Optoelectronics Research Centre, University of Southampton

  • DNA Repair

    • 1st Edition
    • Volume 45
    • English
    DNA Repair, Volume 45 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair, Translesion polymerases, mechanism and function, The Rev1-Polζ Mutasome: Structure and Interactions in Translesion Synthesis, Challenges for base excision repair enzymes: acquiring access to damaged DNA in chromatin Nucleotide excision repair, DNA damage recognition mechanisms in mammalian nucleotide excision repair, Advances in understanding DNA mismatch repair, and more.

  • Personalized Psychiatry

    • 1st Edition
    • Bernhard Baune
    • English
    Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders.

  • Tilapia Culture

    Second Edition
    • 2nd Edition
    • Abdel-Fattah M. El-Sayed
    • English
    Tilapia Culture, Second Edition, covers the vital issues of farmed tilapia in the world, including their biology, environmental requirements, semi-intensive culture, intensive culture systems, nutrition and feeding, reproduction, seed production and larval rearing, stress and disease, harvesting, economics, trade, marketing, the role of tilapia culture in rural development and poverty eradication, and technological innovations in, and the environmental impacts of, tilapia culture. In addition, the book highlights and presents the experiences of leading countries in tilapia culture, thus making it ideal for tilapia farmers and researchers who seek the most relevant research and information. The new second edition not only brings the most updated information within each chapter, but also delivers new content on tilapia transfers, introductions and their impacts, the use of probiotics and other additives in tilapia culture, tilapia trade, including marketing, and sustainability approaches and practices, such as management practices, ecosystem approaches to tilapia culture, and value chain analyses of tilapia farming.

  • Exosomes

    A Clinical Compendium
    • 1st Edition
    • Lawrence R. Edelstein + 3 more
    • English
    Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomesin the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medicaldisciplines, as well as their role in cell-cell communication. It is intended to serve as a referencesource for clinicians, physicians, and research scientists who wish to gain insight into the mostrecent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine sinceantibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is amajor breakthrough in our understanding of how cells function.

  • The Autoimmune Diseases

    • 6th Edition
    • M. Eric Gershwin + 1 more
    • English
    The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.

  • Nutritional and Health Aspects of Food in Western Europe

    • 1st Edition
    • Susanne Braun + 3 more
    • English
    People were once restricted to food native to their region and produced locally. Today, however, food from any place in the world is available, or can be made available, anywhere else. Often there is no or very little information about the nutritional and health aspects of these foods. Nutrition and Health of Western European Foods: Traditional and Ethnic Diets is part of series that will cover the entire globe and is aimed at filling the knowledge gap from traditional and scientific points of view. This volume provides an analysis of traditional and ethnic foods from Western Europe, including Ireland, the United Kingdom, Netherlands, Belgium, Luxembourg, France, and Germany. It also addresses the history of use, composition, preparation, ingredient origin, nutritional aspects, and health effects of various foods and food products in each of these countries. Nutrition and Health of Western European Foods: Traditional and Ethnic Diets ultimately presents both local and international regulations, providing suggestions to harmonize these regulations and promote global availability of these foods.

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