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    • Stem Cell Epigenetics

      • 1st Edition
      • Volume 17
      • August 5, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 1 4 0 8 5 7
      • eBook
        9 7 8 0 1 2 8 1 4 0 8 6 4
      Growing evidence suggests that epigenetic mechanisms play a central role in stem cell biology and are vital for determining gene expression during cellular differentiation and governing mammalian development. In Stem Cell Epigenetics, leading international researchers examine how chromatin regulation and bona fide epigenetic mechanisms underlie stem cell renewal and differentiation. Authors also explore how the diversity of cell types, including the extent revealed by single cell omic approaches, is achieved, and how such processes may be reversed or managed via epigenetic reprogramming.Topics discussed include chromatin in pluripotency, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, stem cells and cancer, epigenetics and disease modeling, brain organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation, non-coding RNAs in pluripotency and early differentiation, and diseases caused by epigenetic alterations in stem cells. Additionally, the book discusses the potential implementation of stem cell epigenetics in drug discovery, regenerative medicine, and disease treatment. Stem Cell Epigenetics will provide researchers and physicians with a state-of-the-art map to orient across the frontiers of this fast-evolving field.

    • The Material Basis of Energy Transitions

      • 1st Edition
      • August 5, 2020
      • Alena Bleicher + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 5 3 4 5
      • eBook
        9 7 8 0 1 2 8 2 3 5 5 4 6
      The Material Basis of Energy Transitions explores the intersection between critical raw material provision and the energy system. Chapters draw on examples and case studies involving energy technologies (e.g., electric power, transport) and raw material provision (e.g., mining, recycling), and consider these in their regional and global contexts. The book critically discusses issues such as the notion of criticality in the context of a circular economy, approaches for estimating the need for raw materials, certification schemes for raw materials, the role of consumers, and the impact of renewable energy development on resource conflicts. Each chapter deals with a specific issue that characterizes the interdependency between critical raw materials and renewable energies by examining case studies from a particular conceptual perspective. The book is a resource for students and researchers from the social sciences, natural sciences, and engineering, as well as interdisciplinary scholars interested in the field of renewable energies, the circular economy, recycling, transport, and mining. The book is also of interest to policymakers in the fields of renewable energy, recycling, and mining, professionals from the energy and resource industries, as well as energy experts and consultants looking for an interdisciplinary assessment of critical materials.

    • Transcription Factors for Abiotic Stress Tolerance in Plants

      • 1st Edition
      • August 5, 2020
      • Shabir Hussain Wani
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 3 3 4 1
      • eBook
        9 7 8 0 1 2 8 1 9 3 3 5 8
      Transcription Factors for Abiotic Stress Tolerance in Plants highlights advances in the understanding of the regulatory network that impacts plant health and production, providing important insights for improving plant resistance. Plant production worldwide is suffering serious losses due to widespread abiotic stresses increasing as a result of global climate change. Frequently more than one abiotic stress can occur at once, for example extreme temperature and osmotic stress, which increases the complexity of these environmental stresses. Modern genetic engineering technologies are one of the promising tools for development of plants with efficient yields and resilience to abiotic stresses. Hence deciphering the molecular mechanisms and identifying the abiotic stress associated genes that control plant response to abiotic stresses is a vital requirement in developing plants with increased abiotic stress resilience.Addressin... the various complexities of transcriptional regulation, this book includes chapters on cross talk and central regulation, regulatory networks, the role of DOF, WRKY and NAC transcription factors, zinc finger proteins, CRISPR/CAS9-based genome editing, C-Repeat (CRT) binding factors (CBFs)/Dehydration responsive element binding factors (DREBs) and factors impacting salt, cold and phosphorous stress levels, as well as transcriptional modulation of genes involved in nanomaterial-plant interactions.Transcr... Factors for Abiotic Stress Tolerance in Plants provides a useful reference by unravelling the transcriptional regulatory networks in plants. Researchers and advanced students will find this book a valuable reference for understanding this vital area.

    • Advanced Security and Safeguarding in the Nuclear Power Industry

      • 1st Edition
      • August 4, 2020
      • Victor Nian
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 2 5 6 7
      • eBook
        9 7 8 0 1 2 8 1 8 2 5 7 4
      Advanced Security and Safeguarding in the Nuclear Power Industry: State of the art and future challenges presents an overview of a wide ranging scientific, engineering, policy, regulatory, and legal issues facing the nuclear power industry. Editor Victor Nian and his team of contributors deliver a much needed review of the latest developments in safety, security and safeguards (“Three S’s”) as well as other related and important subject matters within and beyond the nuclear power industry. This book is particularly insightful to countries with an interest in developing a nuclear power industry as well as countries where education to improve society’s opinion on nuclear energy is crucial to its future success. Advanced Security and Safeguarding in the Nuclear Power Industry covers the foundations of nuclear power production as well as the benefits and impacts of radiation to human society, international conventions, treaties, and standards on the “Three S’s”, emergency preparedness and response, and civil liability in the event of a nuclear accident.

    • Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

      • 1st Edition
      • August 4, 2020
      • Kamal Dua + 5 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 6 5 8 4
      • eBook
        9 7 8 0 1 2 8 2 0 8 8 8 5
      Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development.

    • Advances in Applied Microbiology

      • 1st Edition
      • Volume 112
      • August 4, 2020
      • Geoffrey M. Gadd + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 7 0 7 9
      • eBook
        9 7 8 0 1 2 8 2 0 7 0 8 6
      Advances in Applied Microbiology, Volume 112, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas. Chapters in this new release include discussions of Microbial mercury transformation: focus on molecules and functions, Peptidoglycan Biosynthesis, Clockwork microbial worlds , Molecular engineering to improve the levels of bioproducts from agricultural and forestry waste by filamentous fungi, Multi-species Biofilms for Resource Recovery from Wastewater, Evasion of host defenses by intracellular Staphylococcus aureus, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.

    • Food Industry Wastes

      • 2nd Edition
      • August 2, 2020
      • Maria R. Kosseva + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 1 2 1 9
      • eBook
        9 7 8 0 1 2 8 1 7 3 7 7 0
      Food Industry Wastes: Assessment and Recuperation of Commodities, Second Edition presents a multidisciplinary view of the latest scientific and economic approaches to food waste management, novel technologies and treatment, their evaluation and assessment. It evaluates and synthesizes knowledge in the areas of food waste management, processing technologies, environmental assessment, and wastewater cleaning. Containing numerous case studies, this book presents food waste valorization via emerging chemical, physical, and biological methods developed for treatment and product recovery.This new edition addresses not only recycling trends but also innovative strategies for food waste prevention. The economic assessments of food waste prevention efforts in different countries are also explored. This book illustrates the emerging environmental technologies that are suitable for the development of both sustainability of the food systems and a sustainable economy. So, this volume is a valuable resource for students and professionals including food scientists, bio/process engineers, waste managers, environmental scientists, policymakers, and food chain supervisors.

    • A Quick Guide to Metabolic Disease Testing Interpretation

      • 2nd Edition
      • July 31, 2020
      • Patricia Jones + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 9 2 6 1
      • eBook
        9 7 8 0 1 2 8 1 6 9 2 7 8
      Accurate interpretation of the organic acid chromatographs obtained from the gas chromatography/mass spectrometry requires a significant amount of practice. Pattern recognition is an important factor and a skill that is gained through time and effort. A Quick Guide to Metabolic Disease Testing Interpretation, Second Edition, provides these example chromatographs demonstrating specific disease-related metabolites for the inborn error of metabolism diagnosed via this method. One or more representative chromatographs from each of the common disorders is presented, with the important compounds noted on the chromatographs. This is a must-have for laboratory and medical professionals who interpret testing for the diagnosis and monitoring of IEM.

    • The Bioarchaeology of Metabolic Bone Disease

      • 2nd Edition
      • July 30, 2020
      • Megan B. Brickley + 2 more
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 0 2 0 4
      • eBook
        9 7 8 0 0 8 1 0 2 2 7 8 8
      The Bioarchaeology of Metabolic Bone Disease, Second Edition is a comprehensive source dedicated to better understanding this group of conditions that have significant consequences for health in both past and present communities on a global scale. This edition presents an updated introduction to the biology and metabolism of mineralised tissues that are fundamental to understanding the expression of the metabolic bone diseases in skeletal remains. The extensive advances in understanding of these conditions in both bioarchaeological and biomedical work are brought together for the reader. Dedicated chapters focussing on each disease emphasise the integration of up-to-date clinical background with the biological basis of disease progression to give guidance on identification. New chapters covering anaemia and approaches to recognising the co-occurrence of pathological conditions have been included, reflecting recent advances in research. Boxes highlighting significant issues, use of information from sources such as texts and nonhuman primates, and theoretical approaches are included in the text. Each chapter closes with ‘Core Concepts’ that summarise key information. The final chapter reviews current challenges in bioarchaeology and provides directions for future research. This is a must-have resource for users at all career stages interested in integrating information on the metabolic bone diseases into bioarchaeological projects.

    • An Introduction to Healthcare Informatics

      • 1st Edition
      • July 29, 2020
      • Peter Mccaffrey
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 9 1 5 7
      • eBook
        9 7 8 0 1 2 8 1 4 9 1 6 4
      An Introduction to Healthcare Informatics: Building Data-Driven Tools bridges the gap between the current healthcare IT landscape and cutting edge technologies in data science, cloud infrastructure, application development and even artificial intelligence. Information technology encompasses several rapidly evolving areas, however healthcare as a field suffers from a relatively archaic technology landscape and a lack of curriculum to effectively train its millions of practitioners in the skills they need to utilize data and related tools. The book discusses topics such as data access, data analysis, big data current landscape and application architecture. Additionally, it encompasses a discussion on the future developments in the field. This book provides physicians, nurses and health scientists with the concepts and skills necessary to work with analysts and IT professionals and even perform analysis and application architecture themselves.

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