Skip to main content
Elsevier
View Cart

Academic Press

    • Sirtuin Biology in Cancer and Metabolic Disease

      • 1st Edition
      • February 20, 2021
      • Kenneth Maiese
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 4 6 7 0
      • eBook
        9 7 8 0 1 2 8 2 2 4 8 4 7
      Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes. An exciting prospect for the development of innovative therapeutics for cancer and metabolic disorders involves sirtuins. Sirtuins are histone deacetylases that have an intricate role in the onset and development of cancer and metabolic disease. Implementing a translational medicine format, this innovative reference highlights the ability of sirtuins to oversee critical pathways that involve stem cell maintenance, cellular proliferation, metabolic homeostasis, apoptosis, and autophagy that can impact cellular dysfunction and unchecked cellular growth that can occur during cancer and metabolic disease. Each chapter offers an intuitive perspective of advances on the application of sirtuin pathways for cancer and metabolic disease that will be become a "go-to" resource for a broad audience of scientists, physicians, pharmaceutical industry experts, nutritionists, and students.

    • An AGI Brain for a Robot

      • 1st Edition
      • February 19, 2021
      • John H. Andreae
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 2 5 4 8
      • eBook
        9 7 8 0 3 2 3 9 0 0 0 8 9
      An AGI Brain for a Robot is the first and only book to give a detailed account and practical demonstration of an Artificial General Intelligence (AGI). The brain is to be implemented in fast parallel hardware and embodied in the head of a robot moving in the real world. Associative learning is shown to be a powerful technique for novelty seeking, language learning, and planning. This book is for neuroscientists, robot designers, psychologists, philosophers and anyone curious about the evolution of the human brain and its specialized functions. The overarching message of this book is that an AGI, as the brain of a robot, is within our grasp and would work like our own brains. The featured brain, called PP, is not a computer program. Instead, PP is a collection of networks of associations built from J. A. Fodor’s modules and the author’s groups. The associations are acquired by intimate interaction between PP in its robot body and the real world. Simulations of PP in one of two robots in a simple world demonstrate PP learning from the second robot, which is under human control. "Both Professor Daniel C. Dennett and Professor Michael A. Arbib independently likened the book　‘An AGI Brain for a Robot’　to Valentino Braitenberg’s 1984 book　‘Vehicles: Experiments in Synthetic Psychology’." Daniel C. Dennett, Professor of Philosophy and Director of Center for Cognitive Studies, Tufts University. Author of "From Bacteria to Bach and Back: The Evolution of Minds."　 "Michael Arbib, a long time expert in brain modeling, observed that sometimes a small book can catch the interest of readers where a large book can overwhelm and turn them away. He noted, in particular, the success of Valentino Braitenberg’s ‘Vehicles’ (for which he wrote the foreword). At a time of explosive interest in AI, he suggests that PP and its antics may be just the right way to ease a larger audience into thinking about the technicalities of creating general artificial intelligence." Michael A Arbib, Professor Emeritus of Computer Science, Biomedical Engineering, Biological Sciences and Psychology, University of Southern California. Author of "How the Brain Got Language". "Robots seem to increasingly invade our lives, to the point that sometimes seems threatening and other-worldly. In this small book, John Andreae shows some of the basic principles of robotics in ways that are entertaining and easily understood, and touch on some of the basic questions of how the mind works." Michael C. Corballis, Professor of Psychology, University of Auckland. Author of "The Recursive Mind". "A little book that punches far beyond its weight." Nicholas Humphrey, Emeritus Professor of Psychology, London School of Economics. Author of "Soul Dust: The Magic of Consciousness". "A bold and rich approach to one of the major challenges for neuroscience, robotics and philosophy. Who will take up Andreae’s challenge and implement his model?" Matthew Cobb, Professor of Zoology, University of Manchester. Author of "The Idea of the Brain". "Here is a book that could change the direction of research into artificial general intelligence in a very productive and profitable way. It describes a radical new theory of the brain that goes some way towards answering many difficult questions concerning learning, planning, language, and even consciousness. Almost incredibly, the theory is operational, and expressed in a form that could—and should—inspire future, novel, research in AI that transcends existing paradigms." Ian H. Witten, Professor of Computer Science, Waikato University. Author with Eibe Frank of "Data Mining: Practical Machine Learning Tools and Techniques".

    • Constitutive Modeling of Engineering Materials

      • 1st Edition
      • February 18, 2021
      • Vladimir Buljak + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 6 9 6 5
      • eBook
        9 7 8 0 1 2 8 1 4 6 9 7 2
      Constitutive Modeling of Engineering Materials provides an extensive theoretical overview of elastic, plastic, damage, and fracture models, giving readers the foundational knowledge needed to successfully apply them to and solve common engineering material problems. Particular attention is given to inverse analysis, parameter identification, and the numerical implementation of models with the finite element method. Application in practice is discussed in detail, showing examples of working computer programs for simple constitutive behaviors. Examples explore the important components of material modeling which form the building blocks of any complex constitutive behavior.

    • Second-Order Consensus of Continuous-Time Multi-Agent Systems

      • 1st Edition
      • February 18, 2021
      • Huaqing Li + 6 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 1 3 1 4
      • eBook
        9 7 8 0 3 2 3 9 0 1 3 2 1
      Second-Order Consensus of Continuous-Time Multi-Agent Systems focuses on the characteristics and features of second-order agents, communication networks, and control protocols/algorithms in continuous consensus of multi-agent systems. The book provides readers with background on consensus control of multi-agent systems and introduces the intrinsic characteristics of second-order agents’ behavior, including the development of continuous control protocols/algorithms over various types of underlying communication networks, as well as the implementation of computation- and communication-effici... strategies in the execution of protocols/algorithms... The book's authors also provide coverage of the frameworks of stability analysis, algebraic criteria and performance evaluation. On this basis, the book provides an in-depth study of intrinsic nonlinear dynamics from agents’ perspective, coverage of unbalanced directed topology, random switching topology, event-triggered communication, and random link failure, from a communication networks’ perspective, as well as leader-following control, finite-time control, and global consensus control, from a protocols/algorithms... perspective. Finally, simulation results including practical application examples are presented to illustrate the effectiveness and the practicability of the control protocols and algorithms proposed in this book.

    • Plant Tissue Culture

      • 4th Edition
      • February 17, 2021
      • Sunghun Park
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 1 2 0 5
      • eBook
        9 7 8 0 3 2 3 8 5 1 3 7 4
      Plant Tissue Culture: Techniques and Experiments, Fourth Edition, builds on the classroom tested, audience proven manual that has guided users through successful plant culturing for almost 30 years. The book's experiments demonstrate major concepts and can be conducted with a variety of plant materials readily available throughout the year. This fully updated edition describes the principles of the newest technologies, including CRISPR/Cas9 gene editing and RNAi technology with plant cell and tissue cultures and their applications. Bridging the gap between theory and practice, this book contains detailed methodology supported by comprehensive illustrations, giving users a diverse learning experience for both university students and plant scientists.

    • Artificial Intelligence in Data Mining

      • 1st Edition
      • February 17, 2021
      • D. Binu + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 6 0 1 0
      • eBook
        9 7 8 0 1 2 8 2 0 6 1 6 4
      Artificial Intelligence in Data Mining: Theories and Applications offers a comprehensive introduction to data mining theories, relevant AI techniques, and their many real-world applications. This book is written by experienced engineers for engineers, biomedical engineers, and researchers in neural networks, as well as computer scientists with an interest in the area.

    • Molecular Docking for Computer-Aided Drug Design

      • 1st Edition
      • February 17, 2021
      • Mohane S. Coumar
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 3 1 2 3
      • eBook
        9 7 8 0 1 2 8 2 2 3 1 3 0
      Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery.

    • Test Techniques for Flight Control Systems of Large Transport Aircraft

      • 1st Edition
      • February 16, 2021
      • Yakui Gao + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 9 9 0 3
      • eBook
        9 7 8 0 1 2 8 2 2 9 9 1 0
      Test Techniques for Flight Control Systems of Large Transport Aircraft offers theory and practice of flight control system tests. It is a systematic and practical guide, providing insights to engineers in flight control, particularly those working on system integration and test validation. Ten chapters cover an introduction to flight control system tests, equipment tests and validation, software tests and validation, flight control law and flying qualities evaluation, tests of flight control subsystems, integration and validation based on the iron bird, ground-based test, flight-tests, airworthiness tests and validation, and finally, the current status and prospects for flight control tests and evaluation.

    • The Molecular Immunology of Neurological Diseases

      • 1st Edition
      • February 16, 2021
      • Sunil Kumar
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 9 7 4 4
      • eBook
        9 7 8 0 1 2 8 2 3 2 5 4 5
      The Molecular Immunology of Neurological Diseases provides a comprehensive review of current updates in molecular immunogenetics of different neurological diseases. Readers will learn about the role of immune cells and their modulation strategies to help in the development of therapeutic approaches for both acute and chronic neurodegenerative disorders. There is no other book available on the topic. It has long been thought that the brain is an immune-privilege organ with very limited immune response. However recent studies have made clear that both systemic 'brain' and peripheral 'blood' immune cell responses play key roles in determining brain pathology in neurodegenerative disorders. This book summarizes the role of immune cell activation in the central nervous system microenvironment in acute and chronic neurodegenerative disorders. In addition, it discusses the key role of immune cells and their modulation strategies for the development of current therapeutic approaches.

    • Tailor-Made Polysaccharides in Biomedical Applications

      • 1st Edition
      • February 15, 2021
      • Amit Kumar Nayak + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 3 4 4 5
      • eBook
        9 7 8 0 1 2 8 2 1 3 5 6 8
      Tailor-Made Polysaccharides in Biomedical Applications provides extensive details on all the vital precepts, basics, and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industries. This information provides readers with the foundation for understanding and developing high-quality products. The utilization of natural polymeric excipients in numerous healthcare applications demands the replacement of the synthetic polymers with natural polymers. Natural polymers are superior in terms of biocompatibility, biodegradability, economic extraction, and ready availability. Natural polymers are especially useful in that they are a renewable source of raw materials, as long as they are grown sustainably. Among these natural polymers, polysaccharides are considered as excellent excipients because they are nontoxic, stable, and biodegradable. Several research innovations have been carried out using polysaccharides in drug delivery applications. This book offers a comprehensive resource to understand the potential of these materials in forming new drug delivery methods. It will be useful to biomedical researchers, chemical engineers, regulatory scientists, and students who are actively involved in developing pharmaceutical products for biomedical applications by using tailor-made polysaccharides.

Browse by Publisher

Butterworth-Heinemann

Chandos

Elsevier

Morgan Kaufmann

Newnes

Syngress