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    • Practical Aspects of Vaccine Development

      • 1st Edition
      • September 8, 2021
      • Parag Kolhe + 1 more
      • English
      • Paperback
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      • eBook
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      Practical Aspects of Vaccine Development provides an academic and industry perspective on vaccine development and manufacturing. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and challenges being encountered. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges. Vaccines include a wide range of components including proteins, polysaccharides, protein-polysacchari... conjugates, adjuvants, and more. The container closure system may also be unique, and the product may require freezing storage or lyophilization based on the stability of the vaccine components. Based on the route of delivery, novel technologies and devices may be required. Covering formulation development, manufacture, and delivery considerations of vaccine production, this book is essential to formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students.

    • Spatiotemporal Modeling of Stem Cell Differentiation

      • 1st Edition
      • September 7, 2021
      • William E. Schiesser
      • English
      • Paperback
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      • eBook
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      Spatiotemporal Modeling of Stem Cell Differentiation: Partial Differentiation Equation Analysis in R covers topics surrounding how stem cells evolve into specialized cells during tissue formation and in diseased tissue regeneration. As the process of stem cell differentiation occurs in space and time, the mathematical modeling of spatiotemporal development is expressed in this book as systems of partial differential equations (PDEs). In addition, the book explores important feature of six PDE model which can represent, for example, the development of tissue in organs. In addition, the book covers the computer-based implementation of example models through routines coded (programmed) in R. The routines described in the book are available from a download link so that example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the stem differentiation models, such as changes in the PDE parameters (constants) and the form of the model equations.

    • Encyclopedia of Respiratory Medicine

      • 2nd Edition
      • September 7, 2021
      • Sam Janes
      • English
      • Hardback
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      • eBook
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      Encyclopedia of Respiratory Medicine, Second Edition, Six Volume Set explores the key processes of lung diseases and their diagnosis and management. The book dissects the molecular and cellular biology, physiology and immunology that underpin normal lung function, along with the aberrations that occur in respiratory diseases, from common disorders such as asthma and COPD to rarer lung diseases such as cystic fibrosis, interstitial lung diseases and pulmonary hypertension. Written in at a time when the globe is in the grip of respiratory pandemic, lung disease has never been so prominent in the public and political conscious. This new edition will provide new researchers in respiratory medicine with a solid foundation in unfamiliar topics and will update more experienced researchers seeking to step outside their core areas of research to put their work into a broader context.

    • Deep Learning Models for Medical Imaging

      • 1st Edition
      • September 7, 2021
      • KC Santosh + 2 more
      • English
      • Paperback
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      • eBook
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      Deep Learning Models for Medical Imaging explains the concepts of Deep Learning (DL) and its importance in medical imaging and/or healthcare using two different case studies: a) cytology image analysis and b) coronavirus (COVID-19) prediction, screening, and decision-making, using publicly available datasets in their respective experiments. Of many DL models, custom Convolutional Neural Network (CNN), ResNet, InceptionNet and DenseNet are used. The results follow ‘with’ and ‘without’ transfer learning (including different optimization solutions), in addition to the use of data augmentation and ensemble networks. DL models for medical imaging are suitable for a wide range of readers starting from early career research scholars, professors/scientist... to industrialists.

    • Degradation, Mitigation, and Forecasting Approaches in Thin Film Photovoltaics

      • 1st Edition
      • September 7, 2021
      • Dipankar Deb + 1 more
      • English
      • Paperback
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      • eBook
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      Degradation, Mitigation and Forecasting Approaches in Thin Film Photovoltaics covers detailed descriptions of cell to module level fundamentals of photovoltaics including thin-film materials, performance, maintenance procedures and performance forecasting approaches. Designed to help readers better understand the complexities of photovoltaics, covering the most important aspects of PV cell design, fabrication and performance limiting issues coupled with case studies dedicated towards the forecasting approaches for performance degradations occurring in PV panels. Through theoretical and experimental techniques and methods for performance prediction of the PV cells and modules, this reference concludes with an analysis of the emerging PV technologies for the future. Particularly helpful to researchers because the chapters are aligned in a way that enables readers to start from the fundamentals of PVs and end up with a sound understanding of the current and upcoming PV challenges and ways to deal with them.

    • Novel Psychoactive Substances

      • 2nd Edition
      • September 6, 2021
      • Paul I. Dargan + 1 more
      • English
      • Hardback
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      Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals.

    • Biology and Management of Problematic Crop Weed Species

      • 1st Edition
      • September 4, 2021
      • Bhagirath Chauhan
      • English
      • Paperback
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      Weeds are the main biological constraint to crop production throughout the year. Uncontrolled weeds could cause 100% yield loss. In Australia, the overall cost of weeds to Australian grain growers was estimated at AU$ 3.3 billion annually. In terms of yield losses, weeds amounted to 2.7 million tonnes of grains at a national level. In the USA, weeds cost US$ 33 billion in lost crop production annually. In India, these costs were estimated to be much higher (US$ 11 billion). These studies from different economies suggest that weeds cause substantial yield and economic loss. Biology and Management of Problematic Weed Species details the biology of key weed species, providing vital information on seed germination and production, as well as factors affecting weed growth. These species include Chenopodium album, Chloris truncata and C. virgate, Conyza bonariensis and C. canadensis, Cyperus rotundus, and many more. This information is crucial for researchers and growers to develop integrated weed management (IWM) strategies. Written by leading experts across the globe, this book is an essential read to plant biologists and ecologists, crop scientists, and students and researchers interested in weed science.

    • Inflammation and Oral Cancer

      • 1st Edition
      • September 1, 2021
      • Hiroyuki Tomita
      • English
      • Paperback
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      Inflammation and Oral Cancer: From Bench to Bedside discusses all aspects surrounding the relationship between inflammation and oral cancer, from basic science to the translational research that helps in the optimization of clinical management strategies. The book discusses topics such as chronic inflammation and cancer in oral cavity, the role of HPV in oral inflammation and cancer, rodent models of oral cancer, and epigenetics in oral inflammation and cancer. This is a valuable resource for cancer researchers, oncologists and members of biomedical field who are interested in learning more about the diverse aspects of inflammation and oral cancer. Inflammation in oral mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it can have fundamental clinical consequences, the principal of which can be premalignant lesions throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for oral cancer - therefore it is very important to understand these interactions in detail.

    • Recent Advances in Renewable Energy Technologies

      • 1st Edition
      • August 31, 2021
      • Mejdi Jeguirim
      • English
      • Paperback
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      • eBook
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      Recent Advances in Renewable Energy Technologies is a comprehensive reference covering critical research, laboratory and industry developments on renewable energy technological, production, conversion, storage, and management, including solar energy systems (thermal and photovoltaic), wind energy, hydropower, geothermal energy, bioenergy and hydrogen production, and large-scale development of renewable energy technologies and their impact on the global economy and power capacity. Technological advancements include resources assessment and deployment, materials performance improvement, system optimization and sizing, instrumentation and control, modeling and simulation, regulations, and policies.Each modular chapter examines recent advances in specific renewable energy systems, providing theoretical and applied aspects of system optimization, control and management and supports them with global case studies demonstrating practical applications and economical and environmental aspects through life cycle analysis. The book is of interest to engineering graduates, researchers, professors and industry professionals involved in the renewable energy sector and advanced engineering courses dealing with renewable energy, sources, thermal and electrical energy production and sustainability.

    • Molecular Players in iPSC Technology

      • 1st Edition
      • August 29, 2021
      • Alexander Birbrair
      • English
      • Paperback
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      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Molecular Players in iPSC Technology, Volume 12 addresses the molecular players underlying induced pluripotent stem cell (iPSC) generation, maintenance, expansion, and differentiation. The discovery of iPSCs revolutionized biomedical research. iPSC technology involves multiple molecular mechanisms. This volume covers exosomal microRNAs, auxiliary pluripotency-associa... genes, inducible caspase-9 suicide gene, cell cycle proteins, ion channels, Notch signaling, kinase signaling, SOCS3/JAK2/STAT3 pathway, NANOG, Krüppel-like factors, H1FOO, and much more in iPSCs. The volume is written for researchers and scientists in stem cell therapy, cellular and molecular biology, and regenerative medicine and is contributed by world-renowned authors in the field.

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