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Academic Press

  • Biochemistry of Drug Metabolizing Enzymes

    Trends and Challenges
    • 1st Edition
    • Muhammad Sajid Hamid Akash + 1 more
    • English
    Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction. Chapters explain the biochemistry of DMEs, including biochemical activation, functions, computational approaches, different contaminants on the action and function of DMEs, and describe the importance of DMEs in the drug development process. Conditions covered include metabolic diseases, cardiovascular diseases, neurological diseases, physiological diseases, xenobiotics and inflammatory responses, and their contribution in the malfunctioning of drug metabolizing enzymes. This book is the perfect resource for pharmacology and biochemistry researchers to understand the principles of DMEs. Researchers in the corporate environment will also benefit from the comprehensive list of diseases associated with malfunction of DMEs.
  • Geminivirus: Detection, Diagnosis and Management

    • 1st Edition
    • R.K. Gaur + 2 more
    • English
    Geminivirus: Detection, Diagnosis and Management focuses on the latest techniques for managing diseases caused by these circular, single-stranded (ss) DNA genomes. The most significant impact of plant diseases in host populations is often caused by emerging diseases, whose incidence in a plant host is increasing as a result of long-term changes in their underlying epidemiology. Genetic changes in pathogen and host populations, as well as changes in host ecology and environment, are major factors contributing to disease emergence. Understanding plant virus evolution is crucial for modeling the within-host and between-host dynamics and genetics of virus populations. The book presents a comprehensive review of how these viruses develop, including contributing factors such as population bottlenecks during cell-to-cell movement, systemic colonization, or between-host transmission by different procedures. Presented in five sections—Detection and Diagnosis, Emergence and Diversity, Vector and Transmission, Virus–Host Interaction, and Disease Management, the book includes host range determinant and virulence factors involved in pathogenesis, virus–vector interactions during acquisition, retention, and transmission and evaluating management strategies to control Geminivirus. The book is an essential reference for students and researchers interested in plant virology, particularly begomoviruses, geminiviruses, and vector transmission biology. Introduces identification and characterization of geminiviruses that infect agricultural crops, their wild relatives, and weed hosts Discusses recombination and reassortment mechanisms influencing viral genetic diversity, virulence, and vector transmission Explores the origin, evolution, and bottlenecks of Geminiviruses
  • Advances in Plant Tissue Culture

    Current Developments and Future Trends
    • 1st Edition
    • Avinash Chandra Rai + 3 more
    • English
    Advances in Plant Tissue Culture: Current Developments and Future Trends provides a complete and up-to-date text on all basic and applied aspects of plant tissue cultures and their latest application implications. It will be beneficial for students and early-career researchers of plant sciences and plant/agricultural biotechnology. Plant tissue culture has emerged as a sustainable way to meet the requirements of fresh produces, horticultural crops, medicinal or ornamental plants. Nowadays, plant tissue culture is an emerging filed applied in various aspects, including sustainable agriculture, plant breeding, horticulture and forestry. This book covers the latest technology, broadly applied for crop improvement, clonal propagation, Somatic hybridization Embryo rescue, Germplasm conservation, genetic conservation, or for the preservation of endangered species. However, these technologies also play a vital role in breaking seed dormancy over conventional methods of conservation.
  • Environmental, Physiological and Chemical Controls of Adventitious Rooting in Cuttings

    • 1st Edition
    • Azamal Husen
    • English
    Environmental, Physiological and Chemical Controls of Adventitious Rooting in Cuttings provides a review of the environmental, physiological and chemical controls of adventitious rooting in cuttings obtained from plants. In plants, adventitious roots, which are highly useful for vegetative propagation (or clonal propagation) are produced mainly from leaves, hypocotyls, stems or shoots. Vegetative propagation may occur naturally by using propagules such as roots, underground and aerial stems, leaves, buds and bulbils. It may also be done artificially through regenerative organs (rhizomes, bulbs, and corms) and by utilizing specialized methods, like cutting, grafting and layering. This book covers the latest tactics surrounding these processes. As a plethora of factors affect the adventitious rooting of cuttings, adding to the complexity of the phenomenon. The main factors which control adventitious root formation are types of cuttings, presence of leaf area on cuttings, types of hormones and their concentration, duration of hormonal treatment (quick dip, long soak, dry dip, spray dip, or total immerse method), maturation (juvenile or mature), genotype, explant position, and more, all of which are discussed here.
  • Coenzyme B12 Enzymes Part B

    • 1st Edition
    • Volume 669
    • English
    Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methion... enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-de... enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more.
  • Cybersecurity and Cognitive Science

    • 1st Edition
    • Ahmed Moustafa
    • English
    Cybersecurity and Cognitive Science provides the reader with multiple examples of interactions between cybersecurity, psychology and neuroscience. Specifically, reviewing current research on cognitive skills of network security agents (e.g., situational awareness) as well as individual differences in cognitive measures (e.g., risk taking, impulsivity, procrastination, among others) underlying cybersecurity attacks. Chapters on detection of network attacks as well as detection of cognitive engineering attacks are also included. This book also outlines various modeling frameworks, including agent-based modeling, network modeling, as well as cognitive modeling methods to both understand and improve cybersecurity.
  • The Neuroscience of Autism

    • 1st Edition
    • Rajesh K. Kana
    • English
    The Neuroscience of Autism provides a comprehensive accounting of autism spectrum disorders by integrating scientific findings from behavioral, cognitive and neurobiological research. The book begins by defining autism, identifying characteristics and prevalence, exploring its history, and then moving on to the cognitive and social bases of behavioral symptoms, the brain bases of behavioral and cognitive symptoms, and finally, intervention practices. It examines theoretical models such as weak central coherence, enhanced perceptual functioning, and the extreme male brain hypothesis. Finally, the book addresses the increased attention on the brain connectivity model of autism, looking at the synchronization of brain activity across different brain areas, the causal influence of a brain region on another, and white matter cable connections in the brain.
  • Plant Nematode Biopesticides

    • 1st Edition
    • Anwar L. Bilgrami + 1 more
    • English
    Plant Nematode Biopesticides presents the most current knowledge on various categories of biopesticides used in the management of nematode pests of crops or those that have significant potential as biological control agents. This book presents an exploratory and investigatory compilation and explanation of the actions and potentials of predatory nematodes, microbial agents, plant and other organic products, nanobiopesticides, and predatory invertebrates as biopesticides of nematode pests of agricultural crops. It is of unique importance and value as the only currently available single-volume resource focusing on plant parasitic nematodes as the pests and biopesticides. In addition, the book addresses common reservations in using biopesticides, either alone or in integrated pest management programs, providing advanced insights on various biopesticidal agents and products. Biopesticides may be microbial (nematodes, bacteria, fungi, virus, herbs etc.), plant-incorporated protectants (PIPs), plant products (citronella oil, neem oil, capsaicin, pyrethrin etc.), synthetic biochemical molecules, pheromones, semio-chemicals, plant extracts, or nanobiopesticides.
  • Essential Tremor: Current Concepts and Controversies

    • 1st Edition
    • Volume 163
    • Sheng-Han Kuo + 1 more
    • English
    Tremors, Volume 163 in the International Review in Neurobiology serial highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Collective Intelligence for Smart Cities

    • 1st Edition
    • Chun HO WU + 4 more
    • English
    Collective Intelligence for Smart Cities begins with an overview of the fundamental issues and concepts of smart cities. Surveying the current state-of-the-art research in the field, the book delves deeply into key smart city developments such as health and well-being, transportation, safety, energy, environment and sustainability. In addition, the book focuses on the role of IoT cloud computing and big data, specifically in smart city development. Users will find a unique, overarching perspective that ties together these concepts based on collective intelligence, a concept for quantifying mass activity familiar to many social science and life science researchers.Sections explore how group decision-making emerges from the consensus of the collective, collaborative and competitive activities of many individuals, along with future perspectives.