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    • The Chromosome 22q11.2 Deletion Syndrome

      • 1st Edition
      • August 19, 2022
      • Donna M. McDonald-McGinn
      • English
      • Paperback
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      • eBook
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      The Chromosome 22q11.2 Deletion Syndrome: A Multidisciplinary Approach to Diagnosis and Treatment serves as the first comprehensive, user-friendly resource on the etiology, prognosis, and recurrence risk associated with the chromosome 22q11.2 deletion syndrome. Leading international contributors cover the background, genetics, testing methods, and pathophysiology of 22q11.2DS, placing emphasis on a strong foundation for multidisciplinary treatment strategies. Written by specialists in every applicable subspecialty, such as, cardiology, immunology, endocrinology, gastroenterology, hematology, ophthalmology, neurology, and psychiatry, among other fields. This book presents an authoritative resource with full color images that enhance concept illustration and aid in real-time decision-making. As 22q11.2 deletion syndrome has become a model for understanding rare and frequent anomalies, numerous medical issues, cognitive and behavioral phenotypes, and later onset conditions, this text will become the go to resource for clinicians, researchers, trainees, and motivated family members, in gaining a full understanding of this complex chromosomal disorder.

    • Oral Delivery of Therapeutic Peptides and Proteins

      • 1st Edition
      • August 18, 2022
      • Puneet Tyagi + 1 more
      • English
      • Paperback
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      • eBook
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      Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.

    • Sex and Gender Differences in Neurological Disease

      • 1st Edition
      • Volume 164
      • August 18, 2022
      • English
      • Hardback
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      • eBook
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      International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

    • Cannabis and the Developing Brain

      • 1st Edition
      • August 18, 2022
      • Miriam Melis + 1 more
      • English
      • Paperback
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      • eBook
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      Marijuana is the most commonly used psychotropic drug in the United States, after alcohol. With the legalization and decriminalization of cannabis, momentum continues to build and propelled by the reduction of stigma associated to its consumption, there is growing concern regarding the long-term impact on brain function and behavior. Cannabis and the Developing Brain aims to provide comprehensive research on the effects of cannabis during neurodevelopment stages (i.e., perinatal and adolescent ages). This book introduces readers to vivo neural circuits, molecular and cellular mechanisms affected by cannabis exposure during three different temporal windows of brain vulnerability. Second, it offers a unique insight to shared neurobiological features of cannabinoid exposure during different developmental periods. Lastly, Cannabis and the Developing Brain determines the adverse impact of developmental cannabinoid exposure on specific cognition, emotion and behaviors.

    • Twin Research for Everyone

      • 1st Edition
      • August 17, 2022
      • Adam D. Tarnoki + 3 more
      • English
      • Paperback
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      • eBook
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      Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years. While targeted to undergraduate and graduate students, this compendium will prove a valuable resource for scholars already familiar with twin studies, as well as those coming to the field for the first time. Here, more than forty experts across an array of disciplines examine twinning and twin research methodologies from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods, family and parenting aspects of twinning, twin studies as applied across various disease areas and medical specialties, genetic and epigenetic determinants of differentiation, and academic, neurological and cognitive development. The presentation of existing studies and methods instruction empowers students and researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions.

    • Clinical Immunology

      • 1st Edition
      • August 16, 2022
      • Nima Rezaei
      • English
      • Paperback
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      • eBook
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      Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology.

    • Biotechnology in Healthcare, Volume 2

      • 1st Edition
      • August 14, 2022
      • Debmalya Barh
      • English
      • Paperback
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      • eBook
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      Biotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized healthcare in the last two decades by developing and introducing novel diagnostics, therapeutics, and preventive measures; whether it is noncommunicable or communicable disease, primary or secondary care, or public health, it has shown its immense potential to provide a solution to the healthcare providers, physicians, and allied health care professionals.The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.

    • Artificial Intelligence and Industry 4.0

      • 1st Edition
      • August 14, 2022
      • Aboul Ella Hassanien + 2 more
      • English
      • Paperback
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      • eBook
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      Artificial Intelligence and Industry 4.0 explores recent advancements in blockchain technology and artificial intelligence (AI) as well as their crucial impacts on realizing Industry 4.0 goals. The book explores AI applications in industry including Internet of Things (IoT) and Industrial Internet of Things (IIoT) technology. Chapters explore how AI (machine learning, smart cities, healthcare, Society 5.0, etc.) have numerous potential applications in the Industry 4.0 era. This book is a useful resource for researchers and graduate students in computer science researching and developing AI and the IIoT.

    • Environmental Data Analysis with MatLab or Python

      • 3rd Edition
      • August 14, 2022
      • William Menke
      • English
      • Paperback
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      • eBook
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      Environmental Data Analysis with MATLAB, Third Edition, is a new edition that expands fundamentally on the original with an expanded tutorial approach, more clear organization, new crib sheets, and problem sets providing a clear learning path for students and researchers working to analyze real data sets in the environmental sciences. The work teaches the basics of the underlying theory of data analysis and then reinforces that knowledge with carefully chosen, realistic scenarios, including case studies in each chapter. The new edition is expanded to include applications to Python, an open source software environment. Significant content in Environmental Data Analysis with MATLAB, Third Edition is devoted to teaching how the programs can be effectively used in an environmental data analysis setting. This new edition offers chapters that can both be used as self-contained resources or as a step-by-step guide for students, and is supplemented with data and scripts to demonstrate relevant use cases.

    • A Pharmacology Primer

      • 6th Edition
      • August 14, 2022
      • Terry P. Kenakin
      • English
      • Paperback
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      • eBook
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      A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. With full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics.

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