Biotechnology in Healthcare, Volume 2
Applications and Initiatives
- 1st Edition - August 14, 2022
- Imprint: Academic Press
- Editor: Debmalya Barh
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 0 4 2 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 3 6 4 - 6
Biotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized health… Read more
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Request a sales quoteBiotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized healthcare in the last two decades by developing and introducing novel diagnostics, therapeutics, and preventive measures; whether it is noncommunicable or communicable disease, primary or secondary care, or public health, it has shown its immense potential to provide a solution to the healthcare providers, physicians, and allied health care professionals.
The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.
This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.
The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.
This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.
- Describes various applications of novel biotechnology approaches in healthcare
- Presents applications of biotechnology in primary and secondary healthcare and in public health
- Discusses government initiatives, challenges and opportunities, and entrepreneurship development in the area of healthcare biotechnology
Graduate students and researchers in biotechnology, systems biology, bioinformatics, and several members of biomedical field; clinicians; health policy makers, Healthcare providers
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication page
- Contributors
- About editor
- Preface
- Section I. Applications of biotechnology in healthcare
- Chapter 1. Biotechnology in primary healthcare and hospital management
- 1. Introduction
- 2. Primary healthcare and its importance: current status in India
- 3. Biotechnology applications in primary healthcare
- 4. Biotechnology in hospital management
- 5. Biotechnology-based biosafety
- 6. Challenges and future prospects
- Chapter 2. Biotechnology in public and rural health
- 1. Introduction
- 2. Biotechnology approaches to improve public and rural health
- 3. Advanced biotechnological achievements applied in rural areas
- 4. Environmental biotechnology applied to public and rural health
- 5. Future prospects
- Chapter 3. Invertebrate models in translational research: lessons from Caenorhabditis elegans and Drosophila melanogaster
- 1. Introduction
- 2. Caenorhabditis elegans models for translational research
- 3. Drosophila models for translational research
- 4. Translational impact of invertebrate research
- Glossary
- Chapter 4. Biotechnology for diagnosis, prognosis, and monitoring cancer
- 1. Introduction
- 2. Types of liquid biopsy specimens
- 3. Chemical modifications to increase sensitivity in mutant detection
- 4. Technological approaches for circulating cell analysis
- 5. Technological approaches for extracellular vesicle analysis
- 6. Technological approaches for nucleic acid analysis
- 7. Clinical utility of liquid biopsy analysis
- 8. Concluding remarks and future perspectives
- Chapter 5. Proteolysis-targeting chimeras (PROTACs) as novel biotechnology for cancer therapy
- 1. Introduction
- 2. Advantages and limitations of PROTACs in comparison with small molecule inhibitors
- 3. Small-molecule PROTAC degraders of the bromodomain and extraterminal domain (BET) proteins
- 4. PROTAC degrader of oncoprotein BCR-ABL1
- 5. PROTAC degrader of the Bcl-2 and Bcl-XL
- 6. PROTAC degrader of tyrosine kinase (BTK)
- 7. Degradation of interleukin-1 receptor-associated kinase 4 (IRAK4)
- 8. Degradation of casein kinase 2 (CK2) by PROTAC
- 9. Selective degradation of serine/threonine protein kinase 6, cyclin-dependent kinase (CDK6) by cereblon, VHL, and novel inhibitor of apoptosis (IAP)-recruiting PROTACs based on palbociclib
- 10. Targeted degradation of anaplastic lymphoma kinase by PROTACs
- 11. A potent and selective small-molecule degrader PROTAC SD-36 of signal transducer and activator of transcription 3 (STAT3)
- 12. PROTAC degrader of the human homolog of MDM2 (HDM2)
- 13. Other PROTAC degraders, SNIPERs, and macrocyclic PROTACs
- 14. Molecular glues
- 15. Principles and perspectives on the design of PROTACs
- 16. Conclusions and perspectives
- Chapter 6. Biotechnology applications in neurodegenerative diseases
- 1. Introduction
- 2. Alzheimer's disease
- 3. Parkinson's disease
- 4. Amyotrophic lateral sclerosis
- 5. Huntington's disease
- 6. Biotechnological applications on neurodegenerative diseases
- 7. Stem cells therapy
- 8. Role of medicinal compounds in neurodegenerative diseases
- 9. Conclusions
- Chapter 7. Basic biotechnology applications in viral diseases
- 1. Introduction
- 2. Diagnosis
- 3. Treatment
- 4. Limitations and future prospects
- Chapter 8. Biotechnology applications in infectious disease
- 1. Recombinant protein-based vaccines
- 2. Monoclonal antibodies
- 3. Immunizations with non-viral gene delivery vectors
- 4. Immunizations with viral gene delivery vectors
- 5. Conclusions
- Chapter 9. Biotechnology applications in regenerative medicine
- 1. Introduction
- 2. Conclusions and future direction
- Chapter 10. Biotechnology in the process of assisted reproduction
- 1. Introduction
- 2. Biotechnology in andrology
- 3. Biotechnology in the IVF process
- 4. Early embryo development
- 5. Preimplantation embryo cultivation
- 6. Embryo transfer
- Chapter 11. Biotechnology applications in clinical trials
- 1. Introduction
- 2. Gene therapy in clinical trials
- 3. Peptide and protein-based drugs in clinical trials
- 4. Conclusion
- Chapter 12. Biotechnology applications in precision food
- 1. Introduction
- 2. Precision food for health
- 3. Recent trends of biotechnology in precision food
- 4. Recent trends in precision food
- 5. Challenges and future perspectives
- Section II. Regulatory issues in healthcare biotechnology
- Chapter 13. Mechanisms and applications of probiotics in healthcare industry
- 1. Introduction
- 2. Basic concept of probiotics
- 3. Sources of probiotic bacteria
- 4. Health benefits of probiotics
- 5. Guidelines for the evaluation of probiotics in food
- 6. Mode of action of probiotics
- 7. Probiotics in healthcare
- 8. Conclusions
- Chapter 14. Applications of digital and smart technologies to control SARS-CoV-2 transmission, rapid diagnosis, and monitoring
- 1. Introduction
- 2. Smart and digital technologies
- 3. Digital and smart technologies for practical implementation
- 4. Integration of sectors (clinical, environmental, and emerging digital technologies for research purpose)
- 5. Comparison of digital technology implemented for pandemic monitoring in Western and Eastern culture
- 6. Risks of digital technology
- 7. Ethical perspective
- 8. Steps to ensure data safety
- 9. Future trends
- 10. Conclusion
- Chapter 15. Biotechnology in cosmetics
- 1. Introduction
- 2. Skin and aging
- 3. Biotechnological products used in cosmetics
- 4. Microorganisms that attract attention in the cosmetics industry
- 5. Cell-based cosmetic approaches
- 6. Conclusion
- Chapter 16. Biotechnology focuses on fast-moving consumer goods, pharmaceutical personal care products, medicines, and foods
- 1. Introduction
- 2. What are fast-moving consumer goods?
- 3. Biotechnology and FMCGs
- 4. What are personal care products, and the differences to PPCPs?
- 5. Biotechnology and PPCPs
- 6. What about pharmaceutical products?
- 7. Biotechnology and new pharmaceuticals products
- 8. Food biotechnology and health
- 9. Conclusions and perspectives
- Chapter 17. Government initiatives and policies in healthcare biotechnology
- 1. Introduction
- 2. Healthcare biotechnology
- 3. Role of healthcare biotechnology in improvement of health
- 4. Government initiatives, policies, and regulations-related healthcare biotechnology
- 5. Conclusion
- Chapter 18. Challenges and opportunities in healthcare biotechnology
- 1. Introduction to biotechnology in healthcare
- 2. Economic features of global biotechnology business
- 3. Opportunities and challenges in healthcare biotechnology
- 4. Sustainability of healthcare system
- 5. Conclusion
- Chapter 19. Entrepreneurship in healthcare biotechnology
- 1. Introduction
- 2. The colors of biotechnology
- 3. Biotechnology entrepreneurship
- 4. Healthcare biotechnology
- 5. Challenges and opportunities in entrepreneurship healthcare biotechnology
- 6. Future roadmap
- 7. Conclusions
- Index
- Edition: 1
- Published: August 14, 2022
- No. of pages (Paperback): 386
- No. of pages (eBook): 386
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780323900423
- eBook ISBN: 9780323903646
DB
Debmalya Barh
Dr. Debmalya Barh is currently a Visiting Full Professor (Titular, Grade-E) in Bioinformatics and Precision Health at the Department of Genetics, Ecology, and Evolution, ICB, Federal University of Minas Gerais, Brazil and honorary scientist of the Institute of Integrative Omics and Applied Biotechnology (IIOAB), India. With over 20 years of experience, he has led academic, healthcare, molecular diagnostic, and bioinformatics industry endeavors. He works with more than 400 scientists from 100+ top ranked organizations across 40+ countries and has 220+ publications and a branded editor for 10+ cutting-edge omics related reference books. He is an expert in in precision/personalized health and integrative omics-based biomarker and target discovery in infectious and complex lifestyle diseases.
Affiliations and expertise
Federal University of Minas Gerais, Belo Horizonte, BrazilRead Biotechnology in Healthcare, Volume 2 on ScienceDirect