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Elsevier

Books in Life sciences

  • Molecular Endocrinology

    • 2nd Edition
    • Franklyn F. Bolander
    • English
    Aimed at graduate level courses, this textbook provides students with a solid background in the basics of molecular endocrinology. Molecular Endocrinology, Second Edition, summarizes the area and provides an in-depth discussion of the molecular aspects of hormone action, including hormone-receptor interactions, second messenger generation, gene induction, and post-transcriptional control. Thoroughly revised and updated, the Second Edition includes new information on growth factors, hematopoietic-immune factors, nonclassical hormones, receptors, transduction, transcriptional regulation, as well as other relevant topics.Incorporating an abundance of new information, this text retains the self-contained, focused, and easily readable style of the First Edition. Professionals in related fields will also find this book to be a helpful summary and general reference source.

  • Recent Advances in Animal Nutrition 1988

    • 1st Edition
    • W. Haresign + 1 more
    • English
    Recent Advances in Animal Nutrition 1988 focuses on how feeds affect animal nutrition. The book first discusses problems of raw ingredient variability; European legumes in diets for non-ruminants; and the implications of vitamin E and free radical formation for animal nutrition. The text also underscores approaches to enhance growth in pigs. Growth hormone injection, enzyme supplementation, somatostatin immunization, and probiotics are noted. The book then highlights the nutritional requirements of turkeys to meet market demands. Early bodyweight and subsequent growth rate; nutrition and meat yields; commercial recommendations; and traditional farm-fresh turkeys are discussed. The text also discusses the mineral and trace element requirements of poultry; response of laying hens to energy and amino acids; and prediction of the metabolizable energy content of compound feeds and nutrient allowances for ruminants. The selection is a vital source of data for readers interested in studying animal nutrition.

  • International Review of Forestry Research

    Volume 1
    • 1st Edition
    • John A. Romberger + 1 more
    • English
    International Review of Forestry Research, Volume 1 is a collection of reviews and summaries of world literature concerning defined problem areas in forestry research. This book is composed of seven chapters, and starts with a general survey of the historical development of international forestry research, specifically in Central Europe, since the origin of forest management and of forestry as a science lies on it. This historical development includes historical methods in the practice of forest science, human influences, economics, culture, and laws. The subsequent chapters describe the methods for improvement of forest growth on swamps, the concept of nutrient requirement in forestry, and the methods for determining nutrient requirements of forest trees and stands. These topics are followed by discussions on the biological and environmental aspects of forest site appraisal systems; the anatomy, chemistry, and physiology of bark; and advances in the physiology and biochemistry of tree seeds during maturation, storage, and germination. The concluding chapter considers the development of harmonious control in agricultural, horticultural, and forestry crops, as well as the human influence on regulation and determination of insect populations. This book will prove useful to forest scientists, research workers, teachers, advanced students, administrators, economists, and forest and land managers.

  • Man and Biologically Active Substances

    The Effect of Drugs, Diet and Pollution on Health
    • 1st Edition
    • I. I. Brekhman
    • English
    Man and Biologically Active Substances: The Effect of Drugs, Diet and Pollution on Health discusses the theory and the aims of pharmacosanation; the pharmacosanation medicaments; and the future of pharmacosanation.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 2, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in mollusks. The book contains four chapters and begins with a discussion of neural control of cephalopod behavior. Subsequent chapters deal with the neuroanatomy of selected gastropod species; molluscan membranes, gates, and channels; and molluscan transmitters and modulators.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 3
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activity studies; and the mode of action of anticoagulants structurally and functionally related to vitamin K. The text also describes the design of beta-blocking drugs, biologically active acridines, local anesthetics, and insect chemosterilants. The molecular approach for designing inhibitors to enzymes involved in blood clotting is also considered. Chemists, pharmacologists, and people involved in drug design.

  • Bioelectric Recording Techniques

    Electroencephalography and Human Brain Potentials
    • 1st Edition
    • Richard F. Thompson + 1 more
    • English
    Bioelectric Recording Techniques Part B: Electroencephalograp... and Human Brain Potentials is part of the multivolume series Methods in Physiological Psychology. The series begins with the treatment of bioelectric recording techniques in three volumes (Parts A, B, and C). Part B deals with electroencephalograp... (EEG) and peripheral recording of brain events in man. The book is organized into three parts. The first part deals with EEG recording in animals and man, beginning with a historical review of EEG recording and a comprehensive discussion of modern techniques and experimental problems in recording brain potentials. Also covered are techniques of human EEG recording and abnormal brain activity. The second part deals with evoked human brain potentials. These include a comprehensive discussion of procedures for stimulation and recording of human averaged evoked potentials; methods of analysis of EEG and evoked activity; and the influence of psychological variables and processes on the human averaged evoked scalp potential. The third part treats the contingent negative variation (CNV). This scalp recorded response has occasioned much recent interest, in part because it appears to correlate with ""psychological"" processes.

  • Utilization of Nutrients During Postnatal Development

    International Series of Monographs in Pure and Applied Biology: Zoology
    • 1st Edition
    • P. Hahn + 1 more
    • G. A. Kerkut
    • English
    Utilization of Nutrients during Postnatal Development investigates the nutritional aspects of postnatal development, with emphasis on functions that in some way are closely connected to food, including food intake, digestion, transport, and metabolism. Topics covered range from energy sources and energy balance in starvation to the quantitative and qualitative aspects of food intake. The fate of carbohydrates in infant animals is also discussed, along with the metabolism of lipids during postnatal development. Comprised of eight chapters, this volume begins with an analysis of the most important differences between adult and suckling rats, paying particular attention to thermoregulation and the action of hormones in the early postnatal period. Subsequent chapters deal with the effect of starvation at two environmental temperatures on losses in body weight; protein as an energy source; the absorption of glucose from the gastrointestinal tract; and energy metabolism in the human fetus and newborn. The final chapter is devoted to the late effects of changes in diet composition during the weaning period. This book will be useful for students, practitioners, and researchers in physiology, biology, and developmental nutrition.

  • Stability and Stabilization of Enzymes

    Proceedings of an International Symposium Held in Maastricht, The Netherlands, 22-25 November 1992
    • 1st Edition
    • Volume 47
    • W.J.J. van den Tweel + 2 more
    • English
    These proceedings contain most of the oral presentations and posters of the international symposium on Stability and Stabilization of Enzymes held in Maastricht in November 1992. They provide a comprehensive overview of the state-of-the-art in this field.The possible applications of enzymes are enormous. Years of development have seen many enzymes brought onto the market, but they are still expensive to use. Therefore, their efficient application is a prerequisite for common usage. One of the main factors for this efficiency is the stability of the enzymes. The topics thus ranged from the extensive fundamental thermodynamic knowledge gathered in academic research to the practical applied knowledge built up in industry during the time that enzymes have been produced commercially.The subject Stability and Stabilization of Enzymes was discussed from various points of view, as was reflected in the themes of the symposium sessions. In the session on Fundamentals of Enzyme Stabilisation the thermodynamic background of the phenomenon was highlighted. In yet another session, the recently developed analytical tools to measure enzyme stability and stabilisation were discussed. Further sessions comprised the physical, chemical and biological ways to obtain enzyme stabilisation and finally, the industrial practice of enzyme stabilisation was treated by representatives of the world's most important enzyme producers. The book will be of interest to researchers in universities and industry in the fields of biochemistry, enzymology and biotechnology.

  • Applied Neurophysiology

    With Particular Reference to Anaesthesia
    • 1st Edition
    • J.A. Simpson + 1 more
    • English
    Applied Neurophysiology is intended to promote understanding of the structure and function of the human nervous system for anesthetists. For that reason this book presented concepts rather than critical discussions of experimental work. This book is organized into five parts. There are chapters intended for specialists such as those on vision, control of gaze, hearing and locomotion that were included in order to introduce concepts on brain stem automatisms and cortical function necessary to understand respiration and conscious awareness. There is also a chapter on autonomic nervous system which provides an account of the regulation of the cerebral circulation. The final sections of this volume also include quantitative data and references to original studies which were not thought necessary in other sections. This book will be of interest to anesthetists, clinicians, psychologists, speech pathologists and even neurologists in training.

  • Autoradiography at the Cellular Level

    Physical Techniques in Biological Research
    • 2nd Edition
    • Brigitte Schultze
    • Arthur W. Pollister
    • English
    Physical Techniques in Biological Research, Second Edition, Volume III, Part B: Autoradiography at the Cellular Level focuses on high resolution autoradiography with tritium. This book reviews the different autoradiographic techniques and difficulties in theoretical principles needed for the interpretation of autoradiograms. The topics include the characteristics of the different types of radiation; autoradiographic resolution; techniques for applying photographic emulsions; and autoradiography of water-soluble substances. The application of different isotopes; general aspects of the use of thymidine; physiological RNA synthesis; and RNA synthesis under pathological conditions are also elaborated. This text likewise covers the protein synthesis under normal conditions; electron microscopic autoradiography; application of electron microscopic autoradiography; and autoradiographic methods in cytochemistry. This publication is a good reference for students, researchers, and clinicians conducting work on the use of tritiated compounds in high resolution autoradiography.

  • Assessing Ecological Risks of Biotechnology

    • 1st Edition
    • Lev R. Ginzburg
    • English
    Assessing Ecological Risks of Biotechnology presents a comprehensive analysis of ecological risk assessment for biotechnology as viewed predominantly by scientists doing research in this area, but also by regulators, philosophers, and research managers. The emphasis is on the ecological risks associated with the release of genetically engineered organisms into the environment. The book contains 17 chapters that are organized into four parts. Part I discusses the ecological experience gained from previous biological introductions. Part II explores the ecology and the genetics of microbial communities. Emphasis is given to the transport of microorganisms since one of the major ecological concerns about biotechnology is the danger of the spread of genetically engineered organisms to ecosystems other than the one to which they are released. Part III reviews mathematical models that can be used for ecological risk assessment at four different levels. Part IV concerns the regulation of biotechnology, current research trends, and social values.

  • Practical Botany

    For Advanced Level and Intermediate Students
    • 5th Edition
    • C. J. Wallis
    • English
    Practical Botany for Advanced Level and Intermediate Students, Fifth Edition is a five-part laboratory manual covering the syllabuses in Botany of the advanced level students and other examinations of similar standard. This laboratory manual must be used in conjunction with textbooks of botany. The Introduction presents general instructions for practical work and for the keeping of practical notebooks and a list of apparatus and instruments required, as well as a summary of the characteristics of living organisms, the differences between plants and animals and the principles of plant classification. Part I describes the features and methods of use of the microscope, while Part II contains intensive discussions on the evaluation of the morphological, cytological, and histological aspects of plants. The remaining parts cover the biochemical, physiological, and genetic aspects of the plant experiments. This book is directed toward advanced and intermediate level botany teachers and students.

  • Advances in Metabolic Disorders

    Volume 2
    • 1st Edition
    • Rachmiel Levine + 1 more
    • English
    Advances in Metabolic Disorders discusses the uric acid and gout, the macroglobulins, the metabolism of testosterone in feminizing testes, tryptophan metabolism, and anabolic steroids. It defines the concept of nitrogen-retaining steroids and their use in disease. The book also explains the meaning of macroglobulinemia. The text examines the genetic factors in the development of gout. The technology involved in the control of purine synthesis is analyzed. The nucleotide degradation and uric acid synthesis are explained. The accumulation of uric acid in gout is discussed in detail. The formation of renal stone is explored. A chapter of the book focuses on a group of antibody molecules. This chapter also introduces cytology, hematology, and serology. A section of the volume is devoted to the source of macroglobulins, chromosomal aberrations, the analysis of urinary metabolites and the nature of macroglobulinemia. The book will provide useful information to doctors, students, and researchers in the field of medicine.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 1, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs. The book contains four chapters and begins with a chapter on the behavior of gastropod mollusks. Subsequent chapters deal with learning in gastropod mollusks, the neuronal control of behavior in gastropods, and the development and plasticity of molluscan neurons.

  • Vistas in Botany

    Recent Researches in Plant Taxonomy
    • 1st Edition
    • W. B. Turrill
    • English
    Vistas in Botany, Volume 4: Recent Researchers in Plant Taxonomy covers some of the more important general aspects of plant taxonomy. This volume is composed of seven chapters that link the practice and theory of taxonomy to plant geography, ecology, pollen anatomy, embryology, genetics, and cytology. The opening chapter outlines the views on plant taxonomy classification, the relevance of these views to biological classification, and some of the problems of classification in the non-taxonomic fields of ecology, soil science, and librarianship. The succeeding chapter presents the classification of the spores in higher plants, the cormophytes. This topic is followed by discussions on the embryological characters of taxonomic significance and the interrelations of plant taxonomy, phytogeography, and plant ecology. The final chapters consider the taxonomic preparation of flora and plant fossils. This book will prove useful to taxonomists, botanists, ecologists, and scientists and researchers in the allied fields of botany.

  • Essays in Toxicology

    Volume 2
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 2 covers essays on toxicology and related topics. The book presents essays on fungal toxins, such as mycotoxin, aflatoxin, moldy corn toxicoses, alimentary toxic aleukia, ochratoxin, sporidesmin, zearalenone and other estrogenic compounds, pink rot dermatitis, and slaframine. The text also includes essays on hyperbilirubinemia and cholestasis induced by alpha-naphthylisothi... taurolithocholic acid, and 2-ethyl-2-phenyl butyramide, as different forms of liver injury produced in animals. The evolution of pesticide analyses is also encompassed. Biochemists, physiologists, pathologists, and microbiologists will find the book invaluable.

  • Biochemical Factors Concerned in the Functional Activity of the Nervous System

    First International Meeting of the International Society for Neurochemistry, Strasbourg, 1967
    • 1st Edition
    • D. Richter
    • English
    Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phosphol... complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin... and tyrosine–noradrenali... systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

  • Soil Structure/Soil Biota Interrelationships

    International Workshop on Methods of Research on Soil Structure/Soil Biota Interrelationships, Held at the International Agricultural Centre, Wageningen, The Netherlands, 24-28 November 1991
    • 1st Edition
    • L. Brussaard + 1 more
    • English
    Some pioneers in soil research such as Müller and Kubiëna were as much biologists as they were soil scientists and the legendary biologist Charles Darwin was foresighted in recognizing the earthworms as instrumental in reworking the soil, thereby forming what he called "vegetable mould". Still, soil science has largely been the realm of physicists and chemists over the past decades. Whatever the reason, this picture is rapidly changing. Until recently, research on the transport and transformation of elements in soil was often concerned with either soil biota/plant relationships or with soil structure/plant relationships, if the biota were considered at all, but very few studies explicitly took the interrelationships between soil structure and soil biota into account. The conference on Soil Structure/Soil Biota Interrelationships, held at Wageningen, The Netherlands, 24-28 November 1991, was meant to bridge that gap, focussing on methods of research, organized in three levels: features, processes and effects. The proceedings of the conference are testimony of the need to intertwine the biological, morphological, physical and chemical disciplines in soil research to understand better and forecast soil properties and processes as related to land use for agricultural and other purposes.This book should be of particular interest to soil scientists and ecologists who feel the need for a cross-disciplinary approach in soils research. It should also be a rich source of teaching material for courses in soil science and soil ecology at graduate level and above, with ample reference to studies on land use as related to agriculture and the environment.

  • Advances in Drug Research

    • 1st Edition
    • Volume 22
    • Bernard Testa
    • English
    Advances in Drug Research, Volume 22 focuses on the concepts and facts of drug research. This book is divided into four chapters. Chapter 1 discusses the use of atomic properties and atom-centered indices in QSAR models, while Chapter 2 describes the pharmacokinetics of peptides and proteins. The nuclear receptors, emphasizing the aspects of molecular and genomic pharmacology are elaborated in Chapter 3. The last chapter covers the medicinal chemistry of a vast group of agents acting on nuclear receptors. This publication is valuable to drug researchers and students interested in advances in drugs.

  • Applications of Remote Sensing in Agriculture

    • 1st Edition
    • M. D. Steven + 1 more
    • English
    Applications of Remote Sensing in Agriculture contains the proceedings of the 48th Easter School in Agricultural Science, held at the University of Nottingham on April 3-7, 1989. The meeting invites 146 delegates from over 22 countries and contributions to this book come from nine countries. This book generally presents a review of the achievements of remote sensing in agriculture, establishes the state of the art, and gives pointers to developments. This text is organized into seven parts, wherein Parts I-III cover the principles of remote sensing, climate, soil, land classification, and crop inventories. Productivity; stress; techniques for agricultural applications; and opportunities, progress, and prospects in the field of remote sensing in agriculture are also discussed.

  • Advances in Cellular Neurobiology

    Volume 2
    • 1st Edition
    • Sergey Fedoroff + 1 more
    • English
    Advances in Cellular Neurobiology, Volume 2 discusses the central nervous system, focusing on the structure and function of the brain and spinal cord at cellular level and higher brain functions such as learning, memory, and intelligence. This book is divided into three main sections— cell differentiation and interaction, aging and pathology, and methodologies. The topics discussed include APUD cells and paraneurons: embryonic origin; trophic and specifying factors directed to neuronal cells; and cellular aspects of human brain tumors (gliomas). The astrocyte in liver disease; radioenzymatic methods for analysis of neurotransmitters; and application of immunofluorescence in studies of cytoskeletal antigens are also deliberated in this text. This publication is intended for neurologists, but is also beneficial to students researching on the topographical anatomy and functional relation of the brain and spinal cord.

  • Essays in Toxicology

    Volume 1
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as teratology. The text also includes essays on the significance of methemoglobinemia in toxicology and lead poisoning. Biochemists, plant and animal physiologists, pharmacologists, pathologists, microbiologists, entomologists, food technologist, and people involved in forensic medicine and industrial medicine.

  • Physiology and Toxicology of Male Reproduction

    • 1st Edition
    • James C. Lamb + 1 more
    • English
    Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.

  • Agrammatism

    • 1st Edition
    • Mary-Louise Kean
    • English
    Agrammatism provides an overview of the state of knowledge on agrammatism, typically defined as a disorder of sentence production involving the selective omission of function words and some grammatical endings on words. The book opens with discussions of the diversity of the disorder. This is followed by separate chapters that address primarily questions of syntactic structure in agrammatism, from both linguistic and psycholinguistic perspectives. Within these two gross sections there is no consensus among the conclusions reached by the various authors. However, the position is taken that agrammatism is a disorder distinct from other aphasie disorders of sentence structure. This position is reconsidered in the final two chapters. Because of the intrinsically interdisciplinary character of research on agrammatism, it is hoped that the work presented in this volume will be of interest to linguists and psycholinguists working in areas outside the domain of aphasia, as well as to neurolinguists and neuropsychologists who are already involved in the study of language deficits.

  • Spectroscopic Methods of Analysis

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 9
    • 1st Edition
    • Gunter Zweig + 1 more
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume IX: Spectroscopic Methods of Analysis covers the progress in spectroscopic methods for pesticide analysis. The book discusses the use of high-pressure liquid chromatography coupled to mass spectrometry for the analysis of heat-labile compounds; and the applications of nuclear magnetic resonance spectroscopy and related techniques, and visible and ultraviolet spectrophotometry. The text also describes the applications of spectrophotofluorome... infrared spectrometry, and a collection of infrared spectra of important pesticides. Toxicologists, chemists, and people working in pesticide laboratories will find the book invaluable.

  • Cardiac Pharmacology

    • 1st Edition
    • R. Douglas Wilkerson
    • English
    Cardiac Pharmacology aims to interface basic and clinical knowledge of those interventions used or being studied for use in the treatment of heart disease. The book is divided into four major sections which address intrinsic and neural control of cardiac function, pharmacologic modification of cardiac contractility and cardiac output, the genesis and control of cardiac arrhythmias, and pharmacologic manipulation of myocardial oxygen supply and demand. The last three sections contain a chapter describing the techniques employed in the study of that particular aspect of cardiac function and its alterations by pharmacologic interventions. Cardiologists, pharmacologists, physiologists, and those interested in the area of cardiovascular medicine will find the book insightful.

  • Neurotrauma

    Treatment, Rehabilitation, and Related Issues
    • 1st Edition
    • Michael E. Miner + 1 more
    • English
    Neurotrauma features the papers presented at the Second Houston Conference on Neurotrauma in Texas held in May 1985. These papers cover discussions on patients who have both brain and spinal cord injuries and acute care treatment and investigations of brain injury, as well as rehabilitation strategies and approaches. This second edition is organized into four parts. The first part deals with the treatment of less-than-severe head injury, barbiturate-induced coma, closed head injuries, and severely brain-injured patients. The second part focuses on the evaluation of physiological and anatomical recovery of brain injury patients, while the third part discusses the management of patients with combined head and spinal cord injury. The final part focuses on rehabilitation issues that include nonpharmacological management, the impact of traumatic brain injury on sexuality, and ethical aspects of lifesaving therapeutic strategies. This book may be of interest to persons dealing with studies on the treatment of brain and spinal cord injuries.

  • Blood

    • 1st Edition
    • Walter S. Root + 1 more
    • English
    Physiological Pharmacology, Volume V: Blood describes the interrelationships between pharmacology and blood. This volume is organized into five parts encompassing 16 chapters that consider the effect of therapeutic agents on the physiology of blood, whether it be coagulation, the white cells, red cells, or platelets. The opening part deals first with the physiology of blood coagulation and the mode of action of anticoagulants. This part also covers the mechanism of thrombogenesis and thrombolysis, as well as the in vivo actions of thrombolytic agents. The subsequent parts initially examine the biochemistry and physiology of platelets, hematopoietic stem cells, and white cells. These topics are followed by discussions of the mechanism of thrombocytosis and clinical manifestations of thrombocythemia, as well as the mechanisms of immunologic drug effect on blood cells. These parts also explore the effects of drugs on myelopoiesis and the physiological and immunological activities of lymphocytes. The closing part reviews the iron, vitamin B12, folic acid, erythropoietin, and transferrin components of red blood cells. This part also examines the mechanism of erythropoietic cellular proliferation and the initiation of hyperoxia. This book is intended primarily to physiological pharmacologists, hematologists, and researchers.

  • Biology and Radiobiology of Anucleate Systems

    Bacteria and Animal Cells
    • 1st Edition
    • Silvano Bonotto + 2 more
    • English
    Biology and Radiobiology of Anucleate Systems, I. Bacteria and Animal Cells documents the proceedings of the three-day symposium on Biology and Radiobiology of Anucleate Systems held in Mol, Belgium on June 21-23, 1971. This compilation mainly focuses on the anucleate systems, but some papers dealing with the function of membrane-bound polyribosomes and behavior of isolated cellular organelles are also included. The topics discussed include morphogenesis and synthesis of macromolecules in the absence of the nucleus; production of DNA-less bacteria; and modifications of radiosensitivity in nucleate and anucleate amoeba fragments. The heterogeneity of membrane-bound polyribosomes of mouse myeloma cells in tissue culture; squid giant axon; and cytoplasmic damage leading to delay of oral regeneration in Stentor coeruleus are also elaborated. This book likewise covers the regulation of protein synthesis in anucleate frog oocytes and DNA, RNA, and protein synthesis in anucleate fragments of sea urchin eggs. This publication is a good reference for students and researchers intending to acquire knowledge of the normal and irradiated cell and subtle relations between its nucleus and cytoplasm.

  • Engström-Finean Biological Ultrastructure

    • 2nd Edition
    • J. B. Finean
    • English
    Engström-Finean Biological Ultrastructure, Second Edition, looks upon biological phenomena essentially as patterns of physical and chemical events organized in space and time. It attempts to describe the spatial aspects of this organization, emphasizing in particular the fundamental roles of individual types of molecules. It also introduces a minimum background of fundamental structural information and of techniques so as to aid in the appreciation of the significance of experimental data. The plan of the book in the present edition remains unchanged but the tremendous advances of recent years have necessitated changes in emphasis in the treatment of methods and fundamentals of structure and a complete reappraisal of biological ultrastructure. Key topics discussed include methods in ultrastructural research, the principles of molecular structure; the role of proteins, nucleic acids, lipids, carbohydrates, mineral salts; and the role of ultrastructure in biology and medicine.

  • The Toxicology of Radioactive Substances

    Volume 3.59
    • 1st Edition
    • A. A. Letavet + 1 more
    • English
    The Toxicology of Radioactive Substances, Volume 3: Iron-59 deals with the experimental results of tests conducted at the Radiotoxicology Laboratory of the Institute of Occupational Hygiene and Disease, Academy of Medical Sciences, U.S.S.R. The book focuses on studies made on iron-59, which is widely used in science and technology, such as in the metal industry and in the research of hemoglobin metabolism in the bone marrow and red cells. Other studies show, however, that there is a long-term detrimental effect of intake of iron-59. The text then gives a brief outline of the physical, chemical, and biological properties of iron. Research also shows that the body's reaction to radioactive substances depends on how these are transmitted to the body and on their physicochemical properties. The effect of prolonged administration of radioactive iron on the electrical activity of the cerebral cortex of animals is analyzed, of which, possibly, the nervous system is most affected. The book notes also the changes in the red blood cells during chronic administration of iron-59 in small doses, wherein the hemoglobin levels increased temporarily. Studies of prolonged exposure to radioactive isotopes during pregnancy of the test animals show that there are significant changes in erythropoiesis, associated with iron deficiency. In another study, the prolonged internal administration of radioactive substances showed phasic changes in the height of electrocardiographic waves of the test animals. The text is suitable for physicists, nuclear scientists, doctors of toxicology, and researchers in nuclear medicine.

  • Variation in Chemical Composition of the Nervous System

    As Determined by Developmental and Genetic Factors
    • 1st Edition
    • G. B. Ansell
    • English
    Variation in Chemical Composition of the Nervous System: As Determined by Developmental and Genetic Factors documents the proceedings of the International Neurochemical Conference held in Oxford, 1965. The three years since the last neurochemical meeting have witnessed rapid progress in the whole field of biology, including the development of new concepts based on fresh experimental data and new technical tools. A great deal of concentrated effort have led to advances in the molecular aspects of biological processes ,which have perhaps had most to offer to the formation of new concepts of primary cellular events, especially the genetic mechanism, regulatory cell processes, and protein production. This volume contains 100 chapters that provide an overview of the state of knowledge on the genetic and developmental aspects of the central nervous system. Topics covered include the activity of a plasma logenase in the brain of the developing rat; genetic selection of rats differing in brain biochemistry; the effects of thyroid hormones on steroid deposition in developing chick brain; and developmental changes in the gamma globulins of bovine cerebrospinal fluid.

  • Neuro-Ophthalmology

    • 1st Edition
    • R. Lindsay Rea
    • English
    Neuro-Ophthalmology provides information pertinent to the neuro-ophthalmologic... examination of the eye. This book discusses the anatomy and function of the eye as well as its various diseases. Organized into 17 chapters, this book begins with an overview of the various equipment and methods used in the examination of the eye, including the Snellen's test type, a 13 dioptre lens, and electric ophthalmoscope. This text then discusses the principal reactions of the normal pupil, including the direct light reflex, reflex to accommodation, the spino-pupillary reflex, the psychical reflex, the orbicularis reflex, and the oculo-sensory reflex. Other chapters consider the anatomy of the muscles and nerves of the eye as well as it adnexa. This book discusses as well the condition of optic atrophy and its various types. The final chapter deals with the distinction between headache and neuralgia. This book is a valuable resource for ophthalmic surgeons and ophthalmologists.

  • Food Legislative System of the UK

    • 1st Edition
    • Stephen J. Fallows
    • English
    Food Legislative System of the UK discusses the principles underlying the country's food laws, the historical context of today's food legislation, and the process for amendments in legislation. The book also reviews the influences on the system such as those arising from interest groups, the changing diet, and health environment. In addressing the Food Legislative System of the United Kingdom, the book tackles various examples of food legislation and numerous food- related advisory bodies. Industry, consumer, or enforcement pressures can initiate changes and modifications of laws. Once ministers are convinced that a prima-facie case exists for amending food legislation, they will seek advice from various authorities; make a draft, and present it for full parliamentary procedure. For example, the "Food and Environment Bill" has passed through Parliament by ministers representing the Ministry of Agriculture, Fisheries and Food, while the "Food Bill" has gone through another route with the chief legal officers and company. The book emphasizes the mechanisms through which change is achieved, as well as the points when opportunities exist for interest groups to make their views known to the decision makers. The book can be helpful for food lobbyists, consumer food groups, nutritionists, political scientists, and heads of food and welfare organizations.

  • Additional Principles and Methods of Analysis

    Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Vol. 5
    • 1st Edition
    • Gunter Zweig
    • English
    Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume V: Additional Principles and Methods of Analysis covers the major advances in the analytical techniques used for the qualitative and quantitative determinations of minute amounts of pesticide and plant growth regulator residues in foods and crops. The book discusses developments in analytical methods (i.e. the polarographic technique, thin-layer chromatography) and their general applications; the analytical aspects of pesticide residue analyses in the environment; and specific analytical methods for formulation and residue analyses of insecticides, fungicides, herbicides and plant growth regulators. Agriculturists, agricultural engineers, toxicologists, and people involved in the study of pesticides and biochemicals will find the book invaluable.

  • The Living Barrier

    A Primer on Transfer across Biological Membranes
    • 1st Edition
    • Roy J. Levin
    • English
    The Living Barrier: A Primer on Transfer across Biological Membranes provides information pertinent to the movement of molecules across cell membranes. This book covers a variety of topics, including cell membrane, membrane transfer, water transfer, and movement of charged solutes. Organized into nine chapters, this book begins with an overview of the basic ideas of the cell membrane and reviews the experimental evidence about the structure of the cell membrane. This text then reviews the classical electron microscope pictures of membranes. Other chapters consider the interactions between electrical potentials and the movements of charged substances, which make the membrane transfer of these substances much more complicated than those of neutral molecules. This book discusses as well the aspects of water structure and its influence on membrane permeability. The final chapter deals with the methods by which membranes are synthesized. This book is a valuable resource for biochemists, physiologists, pharmacologists, and botanists.

  • Unit Operations in Food Processing

    • 2nd Edition
    • R. L. Earle
    • English
    This long awaited second edition of a popular textbook has a simple and direct approach to the diversity and complexity of food processing. It explains the principles of operations and illustrates them by individual processes. The new edition has been enlarged to include sections on freezing, drying, psychrometry, and a completely new section on mechanical refrigeration. All the units have been converted to SI measure. Each chapter contains unworked examples to help the student gain a grasp of the subject, and although primarily intended for the student food technologist or process engineer, this book will also be useful to technical workers in the food industry

  • Aspects of Neural Ontogeny

    • 1st Edition
    • A. F. W. Hughes
    • English
    Aspects of Neural Ontogeny focuses on the interaction between the nervous system and peripheral organs during development, including history and development of neurons and the functions of nerves and muscles. The book first offers information on the development of neurons, including formation and growth of nerve fibers; growth cone and the extension of nerve fibers; history of the neuron theory; and path of nerve fibers. The manuscript then elaborates on the innervation of the tetrapod limb and the center and periphery. Discussions focus on the relationships between the ventral horn and muscles of the limb; experimental studies on limb plexus and limb nerves; and relationships between spinal nerves and limb muscles. The publication takes a look at the ontogeny of behavior, as well as pattern of motility, spontaneous movements, tetrapod limb, and experimental studies. The book is a dependable reference for readers interested in neural ontogeny.

  • Biotechnological Innovations in Animal Productivity

    • 1st Edition
    • BIOTOL + 2 more
    • English
    Biotechnological Innovations in Animal Productivity examines the application of biotechnology to animal production. The book focuses on the use of contemporary biotechnology procedures on the different facets of animal production such as the reproductive capabilities of animals, their growth rates, and the ability of the farmer and veterinary services to prevent and cure infection. The text contains chapters that discuss topics on the manipulation of reproductive processes, endocrine regulation of the oestrous cycle, in vitro embryo production and manipulation, vaccines, and the production of transgenic (livestock) animals. Biotechnologists, biologists, and livestock producers will find the book very insightful.

  • The Neostriatum

    Proceedings of a Workshop Sponsored by the European Brain and Behaviour Society, Denmark, 17-19 April 1978
    • 1st Edition
    • Ivan Divac + 1 more
    • English
    The Neostriatum presents the puzzles of the neostriatum from many different angles. This book presents significant findings concerning the structure and neurotransmitters of the neostriatum. Organized into four parts encompassing 20 chapters, this book begins with an overview of the basic organization of the neostriatum. This text then illustrates an impressive complexity of extrinsic and intrinsic neostriatum circuitry. Other chapters consider the view that the nervous system evolved as a hierarchy, so that non-cortical structures such as the corpus striatum retain their structure and function even when the latter is made subservient to more developed mechanisms of the cerebral cortex. This book discusses as well the behavioral roles of the neostriatum and reviews the behavioral data obtained with each of the major treatment and recording techniques. The final chapter deals with the important features of striatal functions. This book is a valuable resource for neuropsychopharmacol... neuropsychologists, neurophysiologists, psychologists, and scientists.

  • Liver Disease

    • 1st Edition
    • A. Paton
    • English
    Liver Disease discusses modern physiological and pathological concepts about liver in a concise manner. The author reviews the liver structure and functions including hepatic clearance, metabolism of carbohydrates, proteins, or fats, as well as the integrity of the liver (dependent on blood flow, blood pressure, oxygen supply, or carbon dioxide concentrations). Investigations of liver diseases involve the following tests: urine, stools, biochemical, hematology, corticosteroids, radiology, biopsy, or peritoneoscopy. The author also discusses hepatitis, cholestatic jaundice, and toxic liver injury. The liver oxidizes around 95 percent of ingested alcohol by conversting it to acetaldehyde, a toxic substance. Anorexia, nausea, vomiting, abdominal pain, or jaundice can follow after alcohol ingestion; gastrointestinal bleeding leads to gastritis or to a ruptured esophageal varices. The author also explains malignant diseases of the liver such as malignant hepatoma, secondary carcinoma or hypernephroma. Other liver diseases include portal cirrhosis and portal hypertension which is blood flow obstruction to either inside or outside the liver. This book is suitable for medical students, laboratory researchers involved in liver diseases, as well as doctors of general medicine.

  • Atlas of the Prenatal Mouse Brain

    • 1st Edition
    • Uta B. Schambra + 1 more
    • English
    The Atlas of the Prenatal Mouse Brain is the latest addition to Academic Press' list of atlases for neuroscientists and neuroscience students. It fills an urgent need for a comprehensive atlas of the developing mouse brain for use in studies of both normal and abnormal development. High-quality photomicrographs of brain sections are depicted in sagittal, coronal, and horizontal planes for four gestational age groups. Each photomicrograph is accompanied by a fully labeled, precision-drawn diagram for easy identification of brain structures. Researchers and students using normal, transgenic, or mutant mouse preparations in developmental neurobiology, neurotoxicology, and biotechnology will welcome this meticulously assembled and accessible guide.

  • Fresh Water from Saline Waters

    The Political, Social, Engineering and Economic Aspects of Desalination
    • 1st Edition
    • Philip Sporn
    • English
    Fresh Water from Saline Waters: The Political, Social, Engineering and Economic Aspects of Desalination examines the political, social, engineering and economic aspects of desalination, with emphasis on the recovery of fresh water from saline waters. The feasibility of combining power generation and distillation is discussed. This book begins with an overview of the history and some basic concepts of desalination, a process that involves artificially taking away or removing the salt from salted water or from sea water. It then presents a brief overall perspective on water supply and its uses in the United States, along with an explanation of the technical principles of distillation with particular reference to evaporation, freezing, and electrodialysis. The desalination process known as multi-stage flash distillation is also considered, together with the principles of combining power generation and distillation and the thermodynamic basis of this integration. The book concludes with an analysis of the economics of nuclear power plants and nuclear heat for distillation. This monograph will be useful for undergraduate students, practitioners, and researchers in engineering, economics, politics, and social sciences.

  • India and the Far East

    A Geography of Disease and Sanitation
    • 3rd Edition
    • James Stevens Simmons + 2 more
    • English
    Global Epidemiology: A Geography of Disease and Sanitation, Volume I presents a survey of the medical, health, and sanitary conditions of various geographic areas of the world. The book brings together certain data, based on surveys made for the Medical Department of the United States Army. This volume includes medical information about India, the Far East, and the Pacific area. The text aims to provide vital information to meet the problems of international health and the spread of disease. The monograph will be of use to epidemiologists, health workers, physicians, and public health experts.

  • Providing Pharmacological Access to the Brain

    Alternate Approaches
    • 1st Edition
    • Volume 21
    • P. Michael Conn + 1 more
    • English
    This volume focuses on contemporary approaches for delivering experimental and therapeutic agents into the brain. The contributions provide methodological details that are typically not available in the literature. Subtleties and shortcuts critical to each procedure are included to facilitate their use by both the experienced researcher and novice.

  • Animal Biotechnology

    Comprehensive Biotechnology, First Supplement
    • 1st Edition
    • L.A. Babiuk + 2 more
    • English
    The advent of biotechnology has the potential to develop a variety of novel or better quality products for the treatment of a large number of diseases in livestock. In addition, as we understand more about the reproductive physiology of animals, the potential exists to dramatically increase the productivity of animals through better therapeutics and diagnostics for the control of many infectious diseases. Productivity can also be increased through animal breeding strategies including gene transfer, micromanipulation of embryos and gamete sex selection. As well as being a valuable reference to current knowledge in these areas, this first supplement to Comprehensive Biotechnology also looks at societal concerns over the use of antibiotics and chemical residues in meat and milk products, which are forcing biotechnologists to investigate more natural means of controlling infection by stimulating the animal's own immune system to combat infection. The identification of a variety of cytokines which are involved in regulating immune responses provides opportunities to use the animal's natural defence mechanisms to combat many infections or increase the animal's resistance to such infections. These approaches should provide tools for eventual elimination of specific diseases from counties, regions or whole continents.

  • Advances in Drug Research

    • 1st Edition
    • Volume 18
    • Bernard Testa
    • English
    Each volume in this distinguished series presents authoritative reviews, both generally, on topics of broad interest in drug research, and specifically, on novel and established therapeutic classes. Acknowledged experts contribute in areas such as drug design, clinical and molecular pharmacology, drug metabolism, and mechanisms of action. Reviewers have consistently praised Advances in Drug Research for its comprehensive and lucid summaries of up-to-date knowledge.

  • The Thermohaline Finestructure of the Ocean

    Pergamon Marine Series
    • 1st Edition
    • K. N. Fedorov
    • J. C. Swallow
    • English
    The Thermohaline Finestructure of the Ocean is a five-chapter text that describes the fine-scale stratification phenomenon in the ocean and the physical processes that participate in its formation and govern its evolution. After an introduction to the concept of thermohaline finestructure of the ocean, this book goes on presenting some methodological aspects in connection with the finestructure measurements in the ocean. The next chapters examine the complex interrelations between the fine-scale stratification of the ocean water. The remaining chapters explore several important physical processes, such as molecular diffusion, convection, turbulence, internal gravity waves, inertial motions, and mean currents. This book is written for physical oceanographers and specialists in other related branches of research.

  • Presynaptic Receptors and Neuronal Transporters

    Official Satellite Symposium to the IUPHAR 1990 Congress Held in Rouen, France, on 26–29 June 1990
    • 1st Edition
    • S.Z. Langer + 2 more
    • English
    Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.

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