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Elsevier

Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 28
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 30
    • English
    In this volume, the medicinal chemistry of the rapidly expanding family of retinoids, of promising semi-synthetic erythromycins and of the multifaceted amidines is reviewed. Another chapter continues the coverage of inorganic elements which have a medical role; recent studies on the various biological roles of manganese are also examined. Inhibition of enkephalin-degrading enzymes is reviewed, as are studies of the digitalis recognition site which are expected to lead to the development of more highly selective inotropic drugs. This work should be of value to medicinal chemists, pharmacists and pharmacologists. It should also be appreciated by all newcomers, as well as those who wish to be kept up to date with recent work on these topics.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 45
    • English

  • Advances in Pharmacology

    • 1st Edition
    • Volume 24
    • English

  • Carotenoids, Part B: Metabolism, Genetics, and Biosynthesis

    • 1st Edition
    • Volume 214
    • John N. Abelson + 1 more
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 44
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 43
    • English

  • Platelets: Receptors, Adhesion, Secretion, Part B

    • 1st Edition
    • Volume 215
    • John N. Abelson + 1 more
    • English
    This volume contains a comprehensive collection of methods for the isolation of platelet membranes, subcellular organelles, the cytoskeleton, and for the assay and purification of platelet receptors.

  • Carotenoids, Part A, Chemistry, Separation, Quantitation, and Antioxidation

    • 1st Edition
    • Volume 213
    • John N. Abelson + 1 more
    • English
    This volume and its companion, volume 214 of Methods in Enzymology, present a comprehensive, state-of-the-art compilation of the molecular and cellular methodology needed for pursuing research with carotenoids.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 27
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 42
    • English

  • International Review of Neurobiology

    • 1st Edition
    • Volume 33
    • English
    Published since 1959, this serial presents in-depth reviews of key topics in neuroscience, from molecules to behavior. The serial stays keenly atuned to recent developments through the contributions of first-class experts in the many fields of neuroscience. Neuroscientists as well as clinicians, psychologists, physiologists and pharmacoloists will find this serial an indispensable addition to their library.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 29
    • English
    The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research. The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT 3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey of the herb feverfew. The volume concludes, as it began, with enzyme inhibition - in this case concerning synthetic inhibitors of interstitial collagenases.

  • Advances in Pharmacology

    • 1st Edition
    • Volume 23
    • English

  • Analytical Profiles of Drug Substances and Excipients

    • 1st Edition
    • Volume 20
    • English
    Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Analytical Profiles of Drug Substances brings this information together into one source.

  • Advances in Pharmacology

    • 1st Edition
    • Volume 22
    • English

  • Cytochrome P450

    Protein-Dna Interactions
    • 1st Edition
    • Volume 206
    • John N. Abelson + 1 more
    • English
    This volume represents the first collection of methodological approaches to P450 investigation which includes the use of molecular biological techniques. It is designed for use by those who study the P450 super family. Methods are presented for the identification and characterization of unique forms of P450 mRNA and protein, for expression of P450s in heterologous systems, for the study of human P450s, and for the characterization of P450s in different tissues.

  • Drug Resistance As a Biochemical Target in Cancer Chemotherapy

    • 1st Edition
    • Makoto Ogawa
    • English
    Drug Resistance as a Biochemical Target in Cancer Chemotherapy covers the proceedings of the 13th Bristol-Myers Squibb Symposium on Cancer Research, entitled ""Drug Resistance as a Biochemical Target in Cancer Chemotherapy"", hosted by the Japanese Foundation for Cancer Research in Tokyo. This book is divided into four parts encompassing 18 chapters that summarize the results of both preclinical and clinical research on circumvention of drug resistance. The first two parts discuss the genetic aspects of multidrug resistance and the proteins involved in drug resistance. These parts also examine the structure, function, and expression of P-glycoproteins, with an emphasis on the role of these proteins as targets for cancer chemotherapy. The third part describes the methods for detection of P-glycoprotein and its antagonists to counter clinical drug resistance. This topic is followed by a discussion on the interactions among steroid hormones, steroid hormone receptors, antiandrogens, biological-response modifiers, and cytotoxic drugs in human breast cancer. The concluding part explores the clinical applications of chemosensitizers in cancer therapy. This part also considers the alternative clinical approaches against drug failure, including non-crosss-resistant therapies, autologous bone marrow transplantation, dose-intensive therapy, and high-dose chemotherapy. Biomedical scientists and researchers and clinicians will find this book invaluable.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 26
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 41
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 40
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 28
    • English
    The six reviews in this volume cover once again a most comprehensive range of topics. The anti-malarial activity of the 8-aminoquinolines is examined, with an eye to the development of a single, broad-spectrum drug. Chelation, important in removal of toxic metals from the body, is reviewed for tripositive elements. A new and promising approach to total parenteral nutrition is described. Our indebtedness to the plant origins of many modern drugs is noted in the context of new chemicals. Heterosteroids and receptor-specific opioid peptides constitute two further topics, each case highlighting the wide range of relevant biologically active compounds. Yet another volume challenging the staggering diversity of the field of medicinal chemistry.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 39
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 25
    • English

  • Advances in Pharmacology

    • 1st Edition
    • Volume 21
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 38
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 27
    • English
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 37
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 24
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 36
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 35
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 23
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 25
    • English
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 34
    • English

  • Vitamins and Coenzymes, Part G

    • 1st Edition
    • Volume 122
    • Nathan P. Colowick + 1 more
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 22
    • English

  • Peptide Growth Factors, Part A

    • 1st Edition
    • Volume 146
    • Nathan P. Colowick + 1 more
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

  • Peptide Growth Factors, Part B

    • 1st Edition
    • Volume 147
    • Nathan P. Colowick + 1 more
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 33
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 21
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 23
    • English
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 32
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 20
    • English

  • Steroids and Isoprenoids, Part B

    • 1st Edition
    • Volume 111
    • Nathan P. Colowick + 1 more
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 22
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 21
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 31
    • English

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 19
    • English

  • Advances in Pharmacology and Chemotherapy

    • 1st Edition
    • Volume 20
    • English

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1st Edition
    • Volume 29
    • English

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