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Elsevier

Books in Life and medical sciences

  • Modern Bioinformatics

    From Molecular Insights to Biomedical Innovation
    • 1st Edition
    • Kolla Bhanu Prakash + 2 more
    • English
    Modern Bioinformatics from Molecular Insights to Biomedical Innovation explores the rapidly advancing field of bioinformatics, addressing a critical gap in current literature by integrating quantum biology and quantum biosensors with computational bioinformatics. As quantum computing and nanotechnology revolutionize biomedical research, this book emerges as an essential resource for researchers navigating these interdisciplinary domains. It caters to the growing need for comprehensive material that bridges molecular biology, computational methods, and cutting-edge innovations, empowering scientists to harness the full potential of bioinformatics in understanding complex biological systems and developing novel diagnostic and therapeutic strategies. Organized into eight thematic sections, the book offers a thorough exploration of bioinformatics from foundational concepts to translational applications. It begins with molecular structures of proteins, DNA, and RNA, advancing through nano-molecular visualization and structural domain analysis. Readers gain insights into deep learning techniques like AlphaFold for protein structure prediction, AI applications in genomics, and molecular interactions critical to function. The text further covers computational methods in drug discovery, forensic bioinformatics, and molecular evolution. A unique emphasis is placed on the convergence of nanotechnology and quantum innovations in molecular diagnostics and biosensing, including quantum biosensors and quantum computing applications. The final sections focus on computational strategies for drug target identification, biomarker discovery, and clinical trial analysis, providing a holistic view of modern bioinformatics workflows. This book is an indispensable reference for advanced researchers, graduate students, and professionals in bioinformatics, molecular biology, and biomedical engineering seeking to integrate quantum computing and nanotechnology into their work.

  • Advanced Computational and Mathematical Approaches in Applied Differential Equations

    • 1st Edition
    • Snehashish Chakraverty + 2 more
    • English
    Advanced Computational and Mathematical Approaches in Applied Differential Equations explores cutting-edge techniques and methodologies in solving complex differential equations, a cornerstone of mathematical modeling across science and engineering. The book bridges theory and application, offering advanced computational strategies and innovative mathematical insights to address real-world problems. Beginning with an overview that presents a unified framework that defines the types of differential equations covered (e.g. ordinary, partial, fractional, fuzzy), the book then progresses to foundations and methods such as Lie symmetries, homotropy, Adomian, FEM, FDM, spectral, machine learning, fuzzy, and fractional derivatives, addressing both computational and mathematical dimensions.Different... equations are fundamental to modeling complex systems, yet solving them often involves significant challenges due to their complexity and nonlinearity. The book equips readers with advanced tools and methodologies to overcome these challenges, providing innovative solutions that improve accuracy, efficiency, and applicability in real-world scenarios. Ideal for researchers, practitioners, and advanced students, it provides a comprehensive resource for tackling challenging applied differential equations with better precision and efficiency.

  • A History of Angiogenesis

    Discoveries, Research and the Therapeutic Potential
    • 1st Edition
    • Gianfranco Natale + 2 more
    • English
    A History of Angiogenesis: Discoveries, Research and the Therapeutic Potential presents a recent history of discoveries in the angiogenic field that contribute to the development of the anatomical knowledge of the process, experimental models, and new pharmacological approaches in different angiogenesis-related diseases. This multifaceted book is enriched with deep scientific contents, and each chapter clearly defines historical steps, the emerging role during the years of new morphological findings, molecular pathways, and targets. Focus is also directed on key challenges associated and future directions.The history of angiogenesis research is an intriguing tool for discovering answers to a wide array of queries arising in the biological and medical world. This comprehensive resource skillfully integrates all the key aspects related to angiogenesis, and will be of immense help to students, researchers, and industry experts who want to explore the last two decades of angiogenesis discoveries and research.

  • Medical Oncology Compendium

    • 1st Edition
    • Ramon Andrade B de Mello
    • English
    Medical Oncology Compendium discusses several important topics in oncology with the help of leading experts worldwide who incorporate not only knowledge on recent developments in the field, but contextualize them within diverse socioeconomic environments to guarantee the applicability of the content in challenging scenarios. The book comprehensively discusses topics such as surgery, radiology, carcinogenesis, screening, assessment tools, evidence-based medicine, and precision oncology as applicable to different cancer types as non-small and small cell lung cancer, mesothelioma, breast cancer, gastric-rectal cancer, female specific cancers, prostate, skin and bone sarcomas.In addition, it discusses options to minimize oncology pain and palliative care. It is a valuable resource for oncologists, clinicians, researchers, healthcare workers and members of biomedical field who needs to understand more about diagnosis, treatment options and support for cancer patients.

  • Encyclopedia of Bioinformatics and Computational Biology

    • 2nd Edition
    • Shoba Ranganathan + 2 more
    • English
    Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.

  • Agent-Based Models with MATLAB

    • 1st Edition
    • Erik Cuevas + 3 more
    • English
    Agent-Based Models with MATLAB introduces Agent-Based Modeling (ABM), one of the most important methodologies for complex systems modeling. The book explores computational implementations and accompanying MATLAB software code as a means of inspiring readers to apply agent-based models to solve a diverse range of problems. It comes with a large amount of software code that accompanies the main text, and the modeling systems described in the book are implemented using MATLAB as the programming language. Despite the heavy mathematical components of Agent-Based Models and complex systems, it is possible to utilize these models without in-depth understanding of their mathematical fundamentals.This book enables computer scientists, mathematicians, researchers, and engineers to apply ABM in a wide range of research and engineering applications. It gradually advances from basic to more advanced methods while reinforcing complex systems through practical, hands-on applications of various computational models.

  • Advances in Cancer Biomarkers Research

    • 1st Edition
    • Anand Narayan Singh + 2 more
    • English
    Advances in Cancer Biomarkers Research provides a thorough and detailed description of cancer biomarkers for diagnostic, prognostic and therapeutics in several cancer types. The book presents a compendium of topics related to current advanced research, along with fundamental knowledge that will help readers fully comprehend the field of cancer biomarkers. Topics discussed include such the role of genetic mechanisms, epigenetics, DNA and microRNA in different cancers, signaling pathways and exosomes. In addition, the book discusses biomarker research applied to several cancer types, such as head and neck, urological, lung, bone tumors, hematological and neurological malignancies and breast cancers.This will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research and treatment.

  • Systematic Review and Meta-Analysis

    Stepwise Approach for Medical and Biomedical Researchers
    • 1st Edition
    • Mahsa Ghajarzadeh + 2 more
    • English
    Systematic Review and Meta-Analysis: Stepwise Approach for Medical and Biomedical Researchers presents a step-by-step approach to develop systematic reviews and meta-analysis for biomedical and medical research. Systematic reviews are the highest quality evidence in medical research, providing an answer to a specific question, and they can be developed in the form of comprehensive literature search, critical appraisal, and synthesis of the evidence. Systematic reviews and meta-analysis are key elements of evidence-based medicine by summarizing the results of previous studies with the use of specific and reliable methods.Initially, systematic review and meta-analysis were exclusive to clinical trials, however systematic reviews of observational and diagnostic studies have expanded, making it essential for members of the field to master those techniques. This practical reference is a valuable resource for biostaticians, researchers, students, and members of medical and biomedical fields who need to understand more about systematic reviews and meta-analysis in their research work.

  • Fixed Point Optimization Algorithms and Their Applications

    • 1st Edition
    • Watcharaporn Cholamjiak
    • English
    Fixed Point Optimization Algorithms and Their Applications discusses how the relationship between fixed point algorithms and optimization problems is connected and demonstrates hands-on applications of the algorithms in fields such as image restoration, signal recovery, and machine learning. The book is divided into nine chapters beginning with foundational concepts of normed linear spaces, Banach spaces, and Hilbert spaces, along with nonlinear operators and useful lemmas and theorems for proving the book’s main results. The author presents algorithms for nonexpansive and generalized nonexpansive mappings in Hilbert space, and presents solutions to many optimization problems across a range of scientific research and real-world applications. From foundational concepts, the book proceeds to present a variety of optimization algorithms, including fixed point theories, convergence theorems, variational inequality problems, minimization problems, split feasibility problems, variational inclusion problems, and equilibrium problems. Fixed Point Optimization Algorithms and Their Applications equips readers with the theoretical mathematics background and necessary tools to tackle challenging optimization problems involving a range of algebraic methods, empowering them to apply these techniques in their research, professional work, or academic pursuits.

  • Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders

    Third International Conference on Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
    • 1st Edition
    • Valentina Rapozzi + 2 more
    • English
    Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders: Third International Conference on Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both preclinical and clinical investigations.This book consists of the following: The program and abstracts presented at the Third International Conference in Udine, Italy, September 3-5, 2023; Parts I–V review on (I) the general properties of nitric oxide in diseases; (II) the role of nitric oxide in cancer; (III) nitric oxide and immunity; (IV) nitric oxide and aging; and (V) nitric oxide and therapeutics. In addition, part VI is an educational review on artificial intelligence and its application in diseases. These updated reviews present many examples of research investigations related to the application of novel therapeutic compounds on nitric oxide and new derivatives, as well as their significant therapeutic activities against various resistant cancers that are unresponsive to current treatments and in different inflammatory disorders.This book is a valuable resource for cancer researchers, oncologists, graduate students, and investigators from medical and biomedical fields who want to learn more about NO and its therapeutic applications in cancer and inflammatory diseases. This book is also highly useful for both clinicians and oncologists as well as pharmaceutical companies involved in the development of new anticancer/antiinfla... agents.