Skip to main content
Elsevier
View Cart

Systematic Review and Meta-Analysis

Stepwise Approach for Medical and Biomedical Researchers

  • 1st Edition - November 29, 2024
  • Latest edition
  • Editors: Mahsa Ghajarzadeh, Sara Hanaei, Nima Rezaei
  • Language: English

Systematic Review and Meta-Analysis: Stepwise Approach for Medical and Biomedical Researchers presents a step-by-step approach to develop systematic reviews and meta-a… Read more

World Book Day celebration

Where learning shapes lives

Up to 25% off trusted resources that support research, study, and discovery.

Explore resources

Description

Systematic Review and Meta-Analysis: Stepwise Approach for Medical and Biomedical Researchers presents a step-by-step approach to develop systematic reviews and meta-analysis for biomedical and medical research. Systematic reviews are the highest quality evidence in medical research, providing an answer to a specific question, and they can be developed in the form of comprehensive literature search, critical appraisal, and synthesis of the evidence. Systematic reviews and meta-analysis are key elements of evidence-based medicine by summarizing the results of previous studies with the use of specific and reliable methods.

Initially, systematic review and meta-analysis were exclusive to clinical trials, however systematic reviews of observational and diagnostic studies have expanded, making it essential for members of the field to master those techniques. This practical reference is a valuable resource for biostaticians, researchers, students, and members of medical and biomedical fields who need to understand more about systematic reviews and meta-analysis in their research work.

Key features

  • Discusses systematic reviews and meta-analysis in a simple and easy to use way that is independent of previous background
  • Presents the essentials of techniques, allowing readers to adapt them to their needs
  • Encompasses practical examples and multimedia content to guarantee the applicability of the lessons

Readership

Biostatiscians, researchers and graduate students in Biostatistics

Table of contents

1. Medical Research: Steps Forward Towards Scientific Advancement

2. Research Methodology: Primary vs. Secondary Studies

3. Systematic Reviews: Definition and Structure

4. Topic Selection: Structured Questions

5. Systematic Search for A Systematic Review

6. Search-Record Screening

7. Data Extraction

8. Risk of Bias Assessment in Included Studies

9. Data Synthesis

10. Performing Meta-Analysis in Different Software

11. Interpretation of Results in Forest Plot

12. Publication Bias and Funnel Plot

13. Heterogeneity Among Included Studies

14. Missing Data in Systematic Reviews

15. Network Meta-Analysis

16. Quality assessment of systematic reviews

17. Scientific Writing in A systematic review

18. Ethics in Systematic Reviews

Product details

  • Edition: 1
  • Latest edition
  • Published: December 5, 2024
  • Language: English

About the editors

MG

Mahsa Ghajarzadeh

Mahsa Ghajarzadeh is an expert epidemiologist who earned her degrees (MD, M.p.H, and Ph.D of epidemiology) from Tehran University of Medical Sciences, and continued her research as a postdoc at Johns Hopkins University. She has great experience in medical research and research education for junior students. She has also published several research papers on systematic reviews and meta-analyses.
Affiliations and expertise
Epidemiologist and Assistant Professor of epidemiology, Tehran University of Medical Sciences, Iran

SH

Sara Hanaei

Dr. Sara Hanaei started medicine at TUMS in 2010 and a Master of Public Health (MPH) in 2014. She graduated with MD-MPH in 2018. She also received TUMS Research Diploma (TUMS-RD) in a 2-year study period from 2013-2015. She was a research assistant at the Research Center for Immunodeficiencies (RCID) from 2018-2021 and further continued neurosurgery as a clinical specialty at TUMS in 2021. She has experience in teaching research skills to students. Medical research was one of her greatest interests since the beginning of her academic education, especially in Neurosurgery and Immunology, therefore, she started research in those fields. Over the past decade, she contributed to different research projects, books, and other research activities including instructing research workshops in statistics, systematic reviews, and meta-analysis. She also got involved in executive tasks and developed executive skills in organizing scientific events, congresses, festivals, scoring, rankings, etc. She also co-edited a 2-volume book: - Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 1 (Neuroimmunology and Neurogenetics) - Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2 (The Path to Bedside Management). In early 2024, she co-founded Borderless Research, Advancement, and Innovation in Neuroscience Network (BRAINet), which was intended to serve in a multidisciplinary and cross-disciplinary manner and embrace all aspects of neuroscience. On this account, different disciplines in neuroscience may come together in the BRAINet including theoretical and molecular neuroscience, clinical neuroscience (neurology), surgical neuroscience (neurosurgery), and social neuroscience. In the light of the borderless collaboration of seniors and juniors, it is provisioned to promote scientific activities and step forward to advancement and innovation in neuroscience.

Affiliations and expertise
Department of Neurosurgery, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences (TUMS); Borderless Research, Advancement and Innovation in Neuroscience Network (BRAINet), Tehran, Iran

NR

Nima Rezaei

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.
Affiliations and expertise
Professor, Department of Immunology, School of Medicine; Head, Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences; Founding President, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA),Universal Scientific Education and Research Network (USERN),Tehran, Iran

View book on ScienceDirect

Read Systematic Review and Meta-Analysis on ScienceDirect