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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Handbook of Greener Synthesis of Nanomaterials and Compounds

    Volume 1: Fundamental Principles and Methods
    • 1st Edition
    • Boris Kharisov + 1 more
    • English
    Modern techniques to produce nanoparticles, nanomaterials, and nanocomposites are based on approaches that frequently involve high costs, inefficiencies, and negative environmental impacts. As such, there has been a real drive to develop and apply approaches that are more efficient and benign. The Handbook of Greener Synthesis of Nanomaterials and Compounds provides a comprehensive review of developments in this field, combining foundational green and nano-chemistry with the key information researchers need to assess, select and apply the most appropriate green synthesis approaches to their own work.Volume 1: Fundamental Principles and Methods provides a clear introduction to the fundamentals of green synthesis that places synthesis in the context of green chemistry. Beginning with a discussion of key greener physical and chemical methods for synthesis, including ultrasound, microwave and mechanochemistry methods, the book goes on to explore biological methods, including biosynthesis, green nanoformation, and virus-assisted methods.

  • Basic Principles of Drug Discovery and Development

    • 2nd Edition
    • Benjamin E. Blass
    • English
    Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.

  • Adsorption: Fundamental Processes and Applications

    • 1st Edition
    • Volume 33
    • Mehrorang Ghaedi
    • English
    Adsorption: Fundamental Processes and Applications, Volume 33 in the Interface Science and Technology Series, discusses the great technological importance of adsorption and describes how adsorbents are used on a large scale as desiccants, catalysts, catalyst supports, in the separation of gases, the purification of liquids, pollution control, and in respiratory protection. Finally, it explores how adsorption phenomena play a vital role in many solid-state reactions and biological mechanisms, as well as stressing the importance of the widespread use of adsorption techniques in the characterization of surface properties and the texture of fine powders.

  • Nontraditional Activation Methods in Green and Sustainable Applications

    Microwaves; Ultrasounds; Photo-, Electro- and Mechanochemistry and High Hydrostatic Pressure
    • 1st Edition
    • Bela Torok + 1 more
    • English
    Nontraditional Activation Methods in Green and Sustainable Applications: Microwaves; Ultrasounds; Photo-, Electro- and Mechan-ochemistry and High Hydrostatic Pressure provides a broad overview of non-traditional activation methods to help readers identify and use appropriate approaches in reducing the environmental impact of their work. Sections discuss the fundamental principles of each method and provide examples of their practical use, illustrating their usefulness. Given the importance of expanding laboratory based technologies to the industrial level, chapters that cover both existing and potential industrial and environmental applications are also included. Highlighting the usefulness and adaptability of these methods for a range of practical applications, this book is a practical guide for both those involved with the design and application of synthetic methodologies and those interested in the implementation and impact of green chemistry principles in practice, from synthetic and medicinal chemists, to food developers and environmental policy planners.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 133
    • English
    Advances in Heterocyclic Chemistry, Volume 133 is the latest release in this definitive series of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review contains comprehensive chapters on Organosilicon azoles: Structure, silylotropy and NMR spectroscopy, Recent advances in the Nenitzescu indole synthesis (1990–2019), One-pot reactions of three-membered rings giving N,O,S-heterocycles, Organometallic complexes of functionalized chelating azines: Part 2, and more.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 68
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 68, covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts surrounding developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products and their exciting developments in phytochemistry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, their uses in new drug developments in the pharmaceutical industry has become increasingly important. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, the ability to rapidly isolate and determine the structures and biological activity of natural products has created opportunities for future drug therapies and uses.

  • Electrochemistry for Bioanalysis

    • 1st Edition
    • Bhavik A. Patel
    • English
    Electrochemistry for Bioanalysis provides a comprehensive understanding of the benefits and challenges of the application of electrochemical and electroanalytical techniques for measurement in biological samples. The book presents detailed information on measurement in a host of various biological samples from single cells, tissues and in vivo. Sections cover real insights surrounding key experimental design and measurement within multiple complex biological environments. Finally, users will find discussions on emerging topics such as electrogenerated chemiluminescence and the use of additive manufacturing for biosensor fabrication. Continuous learning reinforcement throughout the book, including problems for self-assessment, make this an ideal resource.

  • Metal-Organic Frameworks for Chemical Reactions

    From Organic Transformations to Energy Applications
    • 1st Edition
    • Anish Khan + 6 more
    • English
    Metal-Organic Frameworks for Chemical Reactions: From Organic Transformations to Energy Applications brings together the latest information on MOFs materials, covering recent technology in the field of manufacturing and design. The book covers different aspects of reactions from energy storage and catalysts, including preparation, design and characterization techniques of MOFs material and applications. This comprehensive resource is ideal for researchers and advanced students studying metal-organic frameworks in academia and industry. Metal-organic frameworks (MOFs) are nanoporous polymers made up of inorganic metal focuses connected by natural ligands. These entities have become a hot area of research because of their exceptional physical and chemical properties that make them useful in different fields, including medicine, energy and the environment. Since combination conditions strongly affect the properties of these compounds, it is especially important to choose an appropriate synthetic technique that produces a product with homogenous morphology, small size dispersion, and high thermal stability.

  • α-Tertiary Amines en Route to Natural Products

    • 1st Edition
    • Abdul Hameed + 2 more
    • English
    α-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the α,α-disubstituted α-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclo... Acid (ACPD), Total synthesis of cephalotaxine and related molecules, α-amino acids based natural products, α amino acid based natural products and Tetrodotoxin. This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis.

  • Handbook of Analytical Quality by Design

    • 1st Edition
    • Sarwar Beg + 3 more
    • English
    Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 78
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, Volume 78, highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2π Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles and a Biographical Memoire for Leslie Hough.

  • Voids in Materials

    From Unavoidable Defects to Designed Cellular Materials
    • 2nd Edition
    • Gary M. Gladysz + 1 more
    • English
    　 All materials have voids in them, at some scale. Sometimes the voids are ignored, sometimes they are taken into account, and other times they are the focal point of the research. Voids in Materials: From Unavoidable Defects to Designed Cellular Materials takes due notice of all these occurrences, whether designed or unavoidable defects. We define, categorize, and characterize the voids (or empty spaces in materials) and we analyze the effects they have on material properties. This second edition is an updated and expanded central reference for voids in materials and covers all types of voids, intrinsic and intentional, and stochastic and nonstochastic, and the processes and conditions that are needed to create them and is a valuable resource to students in the areas of mechanical engineering, chemical engineering, materials science and engineering, physics, and chemistry, as well as scientists, researchers, and engineers in industry.

  • Theoretical and Computational Approaches to Predicting Ionic Liquid Properties

    • 1st Edition
    • Aswathy Joseph + 1 more
    • English
    Theoretical and Computational Approaches to Predicting Ionic Liquid Properties highlights new approaches to predicting and understanding ionic liquid behavior and selecting ionic liquids based on theoretical knowledge corroborated by experimental studies. Supported throughout with case studies, the book provides a comparison of the accuracy and efficiency of different theoretical approaches. Sections cover the need for integrating theoretical research with experimental data, conformations, electronic structure and non-covalent interactions, microstructures and template effects, thermodynamics and transport properties, and spectro-chemical characteristics. Catalytic and electrochemical properties are then explored, followed by interfacial properties and solvation dynamics. Structured for ease of use, and combining the research knowledge of a global team of experts in the field, this book is an indispensable tool for those involved with the research, development and application of ionic liquids across a vast range of fields.

  • Handbook on the Physics and Chemistry of Rare Earths

    Including Actinides
    • 1st Edition
    • Volume 58
    • Vitalij K. Pecharsky + 1 more
    • English
    Handbook on the Physics and Chemistry of Rare Earths: Including Actinides, Volume 58, the latest release in this continuous series that covers all aspects of rare earth science, including chemistry, life sciences, materials science and physics, presents interesting chapters on Forensic applications of rare earth materials, and Rare earths, the seventeen-position nob.

  • The Curious World of Fluorinated Molecules

    Molecules Containing Fluorine
    • 1st Edition
    • Volume 6
    • Konrad Seppelt
    • English
    The Curious World of Fluorinated Molecules: Molecules Containing Fluorine is the sixth volume in the Progress in Fluorine Science series and is edited by the world-renowned scientist Konrad Seppelt. Dr. Seppelt brings together a team of global experts to uncover the multifaceted nature of the most electronegative element in the Periodic Table. The book explores the fascinating world of unpredictable, fluorine-containing molecules through their discoveries, path to recognition, current state of the art, and impact on the broader fields of fluorinated materials development. This volume will inspire and energize researchers, future scientists, and educators working in fluorine chemistry.

  • Green Chemistry and Water Remediation: Research and Applications

    • 1st Edition
    • Sanjay K. Sharma
    • English
    Green Chemistry and Water Remediation: Research and Applications explores how integrating the principles of green chemistry into remediation research and practice can have a great impact from multiple directions. This volume reviews both common sources of chemical pollution and how using green chemistry as the basis for new or improved remediation techniques can ensure that remediation itself is conducted in a sustainable way. By outlining the main types of chemical pollutants in water and sustainable ways to address them, the authors hope to help chemists identify key areas and encourage them to integrate green chemistry into the design of new processes and products. In addition, the books highlights and encourages the use of the growing range of green remediation approaches available to experts, helping researchers, planners and managers make informed decisions in their selection of remediation techniques.

  • Emerging Carbon Materials for Catalysis

    • 1st Edition
    • Samahe Sadjadi
    • English
    Emerging Carbon Materials for Catalysis covers various carbon-based materials with a focus on their utility for catalysis. Each chapter examines the photo and electrocatalytic applications of a material, including hybrid systems composed of carbon materials. The range of chemical reactions that can be catalyzed with each material—as well as the potential drawbacks of each—are discussed. Covering nanostructured systems, as well as other microstructured materials, the book reviews emerging carbon-based structures, including carbon organic frameworks. Written by a global team of experts, this volume is ideal for graduate students and researchers working in organic chemistry, catalysis, nanochemistry, and nanomaterials.

  • Annual Reports on Computational Chemistry

    • 1st Edition
    • Volume 16
    • David A. Dixon
    • English
    Annual Reports in Computational Chemistry, Volume 16, provides timely and critical reviews of important topics in computational chemistry. Topics covered in this series include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 99
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 99, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this release including chapters on Extracellular vesicle associated proteins as potential biomarkers, Molecular and non-molecular approaches to etiologic diagnosis of gastroenteritis, Circular RNAs and cancer: Opportunities and challenges, Mass spectrometry-based metabolomics for an in-depth questioning of human health, Application of microfluidic technology in cancer research and therapy, Advances in aptasensor technology, and much more.

  • Antifungal Compounds Discovery

    Natural and Synthetic Approaches
    • 1st Edition
    • Marina Sokovic + 1 more
    • English
    Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compounds Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal infections. Beginning with an introduction to both the history and latest developments in this field, the book goes on to provide helpful background information on key fungal species before outlining current antifungal therapies and reasons further development is needed. Detailed chapters then follow reviewing a broad range of natural and synthetic antifungal agents, and discussing the synergistic effect of working with both simultaneously. Finally, the book concludes by considering potential future developments in this important field. Supported with detailed schemes and key information on the biological activity of all selected compounds, Antifungal Compounds Discovery is a comprehensive guide helping researchers understand the relationship between specific chemical structures and their antifungal potency, and a key tool for all those involved in the identification and development of antimicrobial compounds.

  • Analytical Pyrolysis of Natural Organic Polymers

    • 2nd Edition
    • Volume 20
    • S.C. Moldoveanu
    • English
    Analytical Pyrolysis of Natural Organic Polymers, Second Edition, Volume 20 describes the methodology of analytical pyrolysis, the results of pyrolysis for a variety of biopolymers, and several practical applications of analytical pyrolysis on natural organic polymers and their composite materials. The book describes the results of pyrolysis for biopolymers and some chemically modified natural organic polymers. In addition, the many applications of analytical pyrolysis are covered in detail, including topics such as polymer detection used in forensic science, structure elucidation of specific polymers, and identification of small molecules present in polymers (anti-oxidants, plasticizers, etc.).

  • Intra- and Intermolecular Interactions between Non-covalently Bonded Species

    • 1st Edition
    • Elliot R. Bernstein
    • English
    The study of gases, clusters, liquids, and solids as units or systems, eventually focuses on the properties of these systems as governed by interactions between atoms, molecules, and radicals that are not covalently bonded to one another. The stereo/spatial properties of molecular species themselves are similarly controlled, with such interactions found throughout biological, polymeric, and cluster systems and are a central feature of chemical reactions. Nevertheless, these interactions are poorly described and characterized, with efforts to do so, usually based on a particular quantum or even classical mechanical procedure, obscuring the fundamental nature of the interactions in the process. Intra- and Intermolecular Interactions Between Noncovalently Bonded Species addresses this issue directly, defining the nature of the interactions and discussing how they should and should not be described. It reviews both theoretical developments and experimental procedures in order to explore interactions between nonbonded entities in such a fundamental manner as to elucidate their nature and origins. Drawing attention to the extensive experience of its editor and team of expert authors, Intra- and Intermolecular Interactions Between Noncovalently Bonded Species is an indispensable guide to the foundational knowledge, latest advances, most pressing challenges, and future directions for all those whose work is influenced by these interactions.

  • Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

    • 1st Edition
    • Volume 54
    • English
    The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-us... regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 67
    • Atta-ur Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • State Estimation in Chemometrics

    The Kalman Filter and Beyond
    • 2nd Edition
    • Pierre C. Thijssen + 1 more
    • English
    This unique text blends together state estimation and chemometrics for the application of advanced data-processing techniques. State Estimation in Chemometrics, second edition describes the basic methods for chemical analysis—the multicomponent, calibration and titration systems—from a new perspective. It succinctly reviews the history of state estimation and chemometrics and provides examples of its many applications, including classical estimation, state estimation, nonlinear estimation, the multicomponent, calibration and titration systems and the Kalman filter. The concepts are introduced in a logical way and built up systematically to appeal to specialist post-graduates working in this area as well as professionals in other areas of chemistry and engineering. This new edition covers the latest research in chemometrics, appealing to readers in bio-engineering, food science, pharmacy, and the life sciences fostering cross-disciplinary research.

  • Carbohydrates in Drug Discovery and Development

    Synthesis and Application
    • 1st Edition
    • Vinod K. Tiwari
    • English
    Carbohydrates in Drug Discovery and Development: Synthesis and Applications examines recent and notable developments in the synthesis, biology, therapeutic, and biomedical applications of carbohydrates, which is considered to be a highly promising area of research in the field of medicinal chemistry. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell surface recognition formulate the carbohydrate systems to be an exceedingly considerable scaffold for the development of new chemical entities of pharmacological importance. In addition to their easy accessibility, high functionality and chiralpool characteristics are the few additional fascinating structural features of carbohydrates, which further enhance their utilities and thus they have been able to attract chemists and biologists toward harnessing these properties for the past several decades.This book covers an advanced aspect of carbohydrate-based molecular scaffolding, starting with a general introduction followed by a detailed discussion about the impact of diverse carbohydrate-contain... molecules of great therapeutic values and their impact on drug discovery and development. The topics covered in this book include the significance of heparin mimetics as the possible tools for the modulation of biology and therapy, chemistry and bioactivities of C-glycosylated compounds, inositols, iminosugars, KDO, sialic acids, glycohybrids, macrocycles, plant oligosaccharides, anti-bacterial and anti-cancer vaccines, antibiotics, and more.

  • Vibrational Spectroscopy Applications in Biomedical, Pharmaceutical and Food Sciences

    • 1st Edition
    • Andrei A. Bunaciu + 2 more
    • English
    Vibrational Spectroscopy Applications in Biomedical, Pharmaceutical and Food Sciences synthesizes the latest research on the applications of vibrational spectroscopy in biomedical, pharmaceutical and food analysis. Suitable for graduate-level students as well as experienced researchers in academia and industry, this book is organized into five distinct sections. The first deals with the fundamentals of vibrational spectroscopy, with the second presenting the most important sampling methodology used for infrared and Raman spectroscopy in various fields of interest. Since spectroscopy is the study of the interaction of electromagnetic radiation with matter, this section deals with the characteristics, properties and absorption of electromagnetic radiation. Final sections describe the analytical studies performed all over the world in biomedical, pharmaceutical and in the food sciences.

  • Comprehensive Natural Products III

    • 3rd Edition
    • Hung-wen Liu + 1 more
    • English
    Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community.

  • Handbook of Chitin and Chitosan

    Volume 3: Chitin- and Chitosan-based Polymer Materials for Various Applications
    • 1st Edition
    • Sabu Thomas + 2 more
    • English
    The Handbook of Chitin and Chitosan: Chitin and Chitosan Based Polymer Materials for Various Applications, Volume Three, is a must-read for polymer chemists, physicists and engineers interested in the development of ecofriendly micro and nanostructured functional materials based on chitin and their various applications. The book addresses their isolation, preparation and properties and their composites, nanomaterials, manufacturing and characterizations. This is the third of three volumes in a series that contains the latest on the major applications of chitin and chitosan based IPN’s, blends, gels, composites and nanocomposites, including environmental remediation, biomedical applications and smart material applications.

  • Molecular and Laser Spectroscopy

    Advances and Applications: Volume 2
    • 1st Edition
    • V.P. Gupta + 1 more
    • English
    Molecular and Laser Spectroscopy, Advances and Applications: Volume 2 gives students and researchers an up-to-date understanding of the fast-developing area of molecular and laser spectroscopy. This book covers basic principles and advances in several conventional as well as new and upcoming areas of molecular and laser spectroscopy, such as a wide range of applications in medical science, material science, standoff detection, defence and security, chemicals and pharmaceuticals, and environmental science. It covers the latest advancements, both in terms of techniques and applications, and highlights future projections. Editors V.P. Gupta and Yukihiro Ozaki have brought together eminent scientists in different areas of spectroscopy to develop specialized topics in conventional molecular spectroscopy (Cavity ringdown, Matrix Isolation, Intense THz, Far- and Deep- UV, Optogalvanic ), linear and nonlinear laser spectroscopy (Rayleigh & Raman Scattering), Ultrafast Time-resolved spectroscopy, and medical applications of molecular spectroscopy. and advanced material found in research articles. This new volume expands upon the topics covered in the first volume for scientists to learn the latest techniques and put them to practical use in their work.

  • Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters

    Concepts, Methods and Translational Sciences
    • 2nd Edition
    • Shuguang Ma + 1 more
    • English
    Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters, Second Edition, is completely updated to provide an overview of the last decade’s numerous advances in analytical technologies for detection and quantification of drugs, metabolites, and biomarkers. This new edition goes beyond LC-MS and features all-new chapters on how to evaluate drug absorption, distribution, metabolism, and excretion, potential for hepatic and renal toxicity, immunogenicity of biotherapeutics and translational tools for predicting human dosage, safety and efficacy of small molecules and biologics. This book will be an important handbook and desk reference for pharmacologists, toxicologists, clinical scientists, and students interested in the fields of pharmacology, biochemistry, and drug metabolism.

  • Handbook of Chitin and Chitosan

    Volume 1: Preparation and Properties
    • 1st Edition
    • Sabu Thomas + 2 more
    • English
    The Handbook of Chitin and Chitosan: Preparation and Properties, Volume One, is a must-read for polymer chemists, physicists and engineers interested in the development of ecofriendly micro and nanostructured functional materials based on chitin and their various applications. The book addresses the entirety of working with these materials, from their isolation, preparation and properties, through composites, nanomaterials, manufacturing and characterizations. This is the first of three volumes in a series that contains the latest on the major applications of chitin and chitosan based IPN’s, blends, gels, composites and nanocomposites, including environmental remediation, biomedical applications and smart material applications.

  • Separation Methods in Drug Synthesis and Purification

    • 2nd Edition
    • Volume 8
    • Klara Valko
    • English
    Separation Methods in Drug Synthesis and Purification, Second Edition, Volume Eight, provides an updated on the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume combines the two to explain the basic principles and comparisons of each separation technique. New sections to this volume include enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography, the computer simulation of chromatographic separation for accelerating method development, the application of chromatography and capillary electrophoresis used as surrogates for biological processes, and new developments in the established techniques of chromatography and preparative methods.

  • Handbook of Chitin and Chitosan

    Volume 2: Composites and Nanocomposites from Chitin and Chitosan, Manufacturing and Characterisations
    • 1st Edition
    • Sabu Thomas + 2 more
    • English
    The Handbook of Chitin and Chitosan: Composites and Nanocomposites from Chitin and Chitosan, Manufacturing and Characterisations, Volume Two, is a must-read for polymer chemists, physicists and engineers interested in the development of ecofriendly micro and nanostructured functional materials based on chitin and their various applications. The book addresses their isolation, preparation and properties, through composites, nanomaterials, manufacturing and characterizations. This is the second of three volumes in a series that contains the latest on the major applications of chitin and chitosan based IPN’s, blends, gels, composites and nanocomposites, including environmental remediation, biomedical applications and smart material applications.

  • Fascinating Fluoropolymers and Their Applications

    • 1st Edition
    • Bruno Ameduri + 1 more
    • English
    Fluoropolymers are unique materials. Since the middle of the twentieth century fluropolymers have been used in applications where a wide temperature range, a high resistance to aggressive media, excellent tribological characteristics, and specific low adhesion are required. Today, researchers turn to fluoropolymers to solve new challenges and to develop materials with previously unattainable properties. Fascinating Fluoropolymers and Their Applications covers recent developments of fluoropolymer applications in energy, optical fibers, blood substitutes, textile coatings, membranes and other areas, written by experts in these fields. This volume in the Progress in Fluorine Science series is ideal for researchers and engineers who want to learn about the technology and applications of these special polymers, as well as industrial manufacturers who are interested in achieving new product characteristics in their respective industries.

  • Opportunities for Fluoropolymers

    Synthesis, Characterization, Processing, Simulation and Recycling
    • 1st Edition
    • Bruno Ameduri + 1 more
    • English
    Fluoropolymers are very unique materials. Since the middle of the twentieth century fluoropolymers have been used in applications where a wide temperature range, a high resistance to aggressive media, excellent tribological characteristics, and specific low adhesion are required. Today, researchers turn to fluoropolymers to solve new challenges and to develop materials with previously unattainable properties. Opportunities for Fluoropolymers: Synthesis, Characterization, Processing, Simulation and Recycling covers recent developments in fluoropolymers, including synthesis of new copolymers, strategies for radical polymerization of fluoromonomers (conventional or controlled; RDRP), and the modification of fluoropolymers to achieve desired material characteristics. This volume in the Progress in Fluorine Science series is ideal for researchers and engineers who want to learn about the synthetic strategies, properties, and recycling of these special polymers, as well as industrial manufacturers who are interested in achieving new product characteristics in their respective industries.

  • Chemical Analysis of Food

    Techniques and Applications
    • 2nd Edition
    • Yolanda Pico
    • English
    Chemical Analysis of Food: Techniques and Applications, Second Edition, reviews the latest technologies and challenges in all stages of food analysis, from selecting the right approach, how to perform analytic procedures, and how to measure and report the results. The book is structured in two parts: the first describes the role of the latest developments in analytical and bio-analytical techniques, with the second reviewing innovative applications and issues in food analysis. The techniques discussed range from the non-invasive and non-destructive, such as infrared spectroscopy and ultrasound, to newly emerging areas, such as nanotechnology, biosensors and electronic noses and tongues. This thoroughly updated edition includes new chapters on ambient mass spectrometry, imaging techniques, omics approaches in food analysis, natural toxins analysis, food contact materials, nanomaterials and organic foods. All chapters are updated or rewritten to bring the content completely up-to-date.

  • Commercial Biosensors and Their Applications

    Clinical, Food, and Beyond
    • 1st Edition
    • Mustafa Kemal Sezgintürk
    • English
    Commercial Biosensors and Their Applications: Clinical, Food, and Beyond offers professionals an in-depth look at some of the most significant applications of commercially available biosensor-based instrumentation in the clinical, food quality control, bioprocess monitoring, and bio threat fields. Featuring contributions by an international team of scientists, this book provides readers with an unparalleled opportunity to see how their colleagues around the world are using these powerful tools. This book is an indispensable addition to the reference libraries of biosensor technologists, analytical chemists, clinical chemists, biochemists, physicians, medical doctors, engineers, and clinical biochemists. The book discusses the need for portable, rapid, and smart biosensing devices and their use as cost-effective, in situ, real-time analytical tools in a variety of fields.

  • Breathborne Biomarkers and the Human Volatilome

    • 2nd Edition
    • Jonathan Beauchamp + 2 more
    • English
    Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis.

  • Multidimensional Analytical Techniques in Environmental Research

    • 1st Edition
    • Regina Duarte + 1 more
    • English
    Multidimensional Analytical Techniques in Environmental Research is a comprehensive resource on the many multidimensional analytical strategies to qualitatively and quantitatively assess and map the organic and inorganic pollutants in complex atmospheric, water and soil matrices. During the past two decades, the rapidly-evolving field of analytical instrumentation has produced sophisticated multidimensional tools capable of providing unique and in-depth knowledge on the chemical features of complex mixtures from these different environmental matrices. This book brings together the wealth of information in the current literature, assisting in the decision-making process by covering both the fundamentals and applications of these methodologies. Sections cover the wide variety of multidimensional analytical techniques, including multidimensional solution- and solid-state nuclear magnetic resonance (NMR) spectroscopy, ultrahigh-resolution mass spectrometry (MS), two-dimensional correlation spectroscopy, two-dimensional liquid and gas chromatography and capillary electrophoresis coupled to high-resolution detection techniques, and excitation-emission (EEM) fluorescence spectroscopy assisted by multiway data analysis tools, and the use of synchrotron-radiatio... techniques combined with other spectroscopic approaches to explore and map the speciation of elements.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 74
    • Pedro J. Perez
    • English
    Advances in Organometallic Chemistry, Volume 74, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, with this updated release including chapters on Metal dendrimers used in biomedical applications, Sigma-bond activation reactions induced by unsaturated osmium (IV) complexes with bulky phosphines, Base metal pincer complexes, and more.

  • Laser-Induced Breakdown Spectroscopy

    • 2nd Edition
    • Jagdish P. Singh + 1 more
    • English
    Laser-Induced Breakdown Spectroscopy, Second Edition, covers the basic principles and latest developments in instrumentation and applications of Laser Induced Breakdown Spectroscopy (LIBS). Written by active experts in the field, it serves as a useful resource for analytical chemists and spectroscopists, as well as graduate students and researchers engaged in the fields of combustion, environmental science, and planetary and space exploration. This fully revised second edition includes several new chapters on new LIBS techniques as well as several new applications, including flame and off-gas measurement, pharmaceutical samples, defense applications, carbon sequestration and site monitoring, handheld instruments, and more. LIBS has rapidly developed into a major analytical technology with the capability of detecting all chemical elements in a sample, of real- time response, and of close-contact or stand-off analysis of targets. It does not require any sample preparation, unlike conventional spectroscopic analytical techniques. Samples in the form of solids, liquids, gels, gases, plasmas, and biological materials (like teeth, leaves, or blood) can be studied with almost equal ease. This comprehensive reference introduces the topic to readers in a simple, direct, and accessible manner for easy comprehension and maximum utility.

  • Antimalarial Agents

    Design and Mechanism of Action
    • 1st Edition
    • Graham L. Patrick
    • English
    Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world’s population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite’s genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs. Drawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists.

  • Recent Advances in Applications of Name Reactions in Multicomponent Reactions

    • 1st Edition
    • Majid M. Heravi + 1 more
    • English
    Recent Advances in Applications of Name Reactions in Multicomponent Reactions is an ideal reference for researchers and postgraduate students studying organic chemistry, as well as synthetic organic chemists working on the development of novel methodologies for the synthesis of various heterocyclic systems, especially drug design and discovery, in both academia and industry. The book reviews recent applications of name reactions in multicomponents for the synthesis of heterocycles and examines recent advances in applications of significant name reactions, such as Ugi and Passirini, Click, Knoevenagel, Michael, Diels-Alder, Aldol, Mannich, Heck, Huisgen, and Suzuki in MCRs. These reactions can be used in the synthesis of a wide variety of novel heterocycles with different sizes and heteroatoms, as well as in the total synthesis of natural products in order to decrease the number of synthetic steps. Since chiral inductions are necessary for most of these sequential name reactions, their asymmetric catalyzed reactions are also described.

  • Comprehensive Chemometrics

    Chemical and Biochemical Data Analysis
    • 2nd Edition
    • Steven Brown + 2 more
    • English
    Comprehensive Chemometrics, Second Edition, Four Volume Set features expanded and updated coverage, along with new content that covers advances in the field since the previous edition published in 2009. Subject of note include updates in the fields of multidimensional and megavariate data analysis, omics data analysis, big chemical and biochemical data analysis, data fusion and sparse methods. The book follows a similar structure to the previous edition, using the same section titles to frame articles. Many chapters from the previous edition are updated, but there are also many new chapters on the latest developments.

  • Sustainable Seaweed Technologies

    Cultivation, Biorefinery, and Applications
    • 1st Edition
    • Maria Dolores Torres + 2 more
    • English
    Sustainable Seaweed Technologies: Cultivation, Biorefinery, and Applications collates key background information on efficient cultivation and biorefinery of seaweeds, combining underlying chemistry and methodology with industry experience. Beginning with a review of the opportunities for seaweed biorefinery and the varied components and properties of macroalgae, the book then reviews all the key steps needed for industrial applications, from its cultivation, collection and processing, to extraction techniques, concentration and purification. A range of important applications are then discussed, including the production of energy and novel materials from seaweed, before a set of illustrative case studies shows how these various stages work in practice. Drawing on the expert knowledge of a global team of editors and authors, this book is a practical resource for both researchers and businesses who currently work with macroalgae.

  • Chemistry of Nanomaterials

    Fundamentals and Applications
    • 1st Edition
    • Tahir Iqbal Awan + 2 more
    • English
    Chemistry of Nanomaterials: Fundamentals and Applications provides a foundational introduction to this chemistry. Beginning with an introduction to the field of nanoscience and technology, the book goes on to outline a whole range of important effects, interactions and properties. Tools used to assess such properties are discussed, followed by chapters putting this fundamental knowledge in context by providing examples of nanomaterials and their applications in the real world. Drawing on the experience of its expert authors, this book is an accessible introduction to the interactions at play in nanomaterials for both upper-level students and researchers.

  • Recent Trends in Carbohydrate Chemistry

    Synthesis, Structure and Function of Carbohydrates
    • 1st Edition
    • Amélia Pilar Rauter + 4 more
    • English
    Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates　covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry

  • Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles

    • 1st Edition
    • Navjeet Kaur
    • English
    Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates.

  • Transport and Surface Phenomena

    • 1st Edition
    • Kamil Wichterle + 1 more
    • English
    Transport and Surface Phenomena provides an overview of the key transfers taking place in reactions and explores how calculations of momentum, energy and mass transfers can help researchers develop the most appropriate, cost effective solutions to chemical problems. Beginning with a thorough overview of the nature of transport phenomena, the book goes on to explore balances in transport phenomena, including key equations for assessing balances, before concluding by outlining mathematical methods for solving the transfer equations. Drawing on the experience of its expert authors, it is an accessible introduction to the field for students, researchers and professionals working in chemical engineering. The book and is also ideal for those in related fields such as physical chemistry, energy engineering, and materials science, for whom a deeper understanding of these interactions could enhance their work.

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