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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Bleomycin Chemotherapy

    • 1st Edition
    • October 22, 2013
    • Branimir Ivan Sikic + 2 more
    • English
    Bleomycin Chemotherapy focuses on the clinical uses of bleomycin. Bleomycin, a group of glycopeptides isolated from Streptomyces verticillus, has a unique structure and mechanism of action among anticancer drugs. The drug’s remarkable lack of bone marrow toxicity prompted its addition to myelosuppressive regimens and enabled treatment of patients with compromised hematopoietic function. Bleomycin is an integral component of one of the great triumphs of medical oncology—the curative treatment of metastatic testicular carcinomas. Similar curative potential has been demonstrated for bleomycin in combination with cisplatin and vinblastine in germ-cell cancers of the ovary. Bleomycin is included in several important treatment regimens for Hodgkin's disease and non-Hodgkin's lymphomas. The drug also has clinical activity against squamous carcinomas of various sites. These uses and other aspects, including the development of new bleomycin analogs, are discussed in the following chapters, which were first presented at a symposium jointly sponsored by the Northern California Cancer Program and Bristol Laboratories in San Francisco, California, 14-15 September 1984.

  • Conjugate Addition Reactions in Organic Synthesis

    • 1st Edition
    • Volume 9
    • October 22, 2013
    • P. Perlmutter
    • Patrick Perlmutter
    • English
    This book provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic synthesis. The book is organised in terms of the major classes of conjugate acceptors. Within each of these classes, the chemistry and applications of conjugate additions with several different categories of nucleophiles have been examined. Where several different nucleophiles achieve the same synthetic transformation, they are cross-referenced within the book and qualitative comparisons offered where appropriate. Examples of the use of conjugate additions in total synthesis of important molecules are included, with a special emphasis throughout the book on stereoselectivity. This will be a useful main text for graduate and postgraduate courses on conjugate addition reactions or the Michael reaction. It could also serve as a supplementary text for courses on topics such as the chemistry of organocopper reagents, enamines and carbanion chemistry.

  • Advances in Structure Research by Diffraction Methods

    Fortschritte der Strukturforschung mit Beugungsmethoden
    • 1st Edition
    • October 22, 2013
    • W. Hoppe + 1 more
    • English
    Advances in Structure Research by Diffraction Methods: Volume 5 presents discussions on application of diffraction methods in structure research. The book provides the aspects of structure research using various diffraction methods. The text contains 2 chapters. Chapter 1 reviews the general theory and experimental methods used in the study of all types of amorphous solid, by both X-ray and neutron diffraction, and the detailed bibliography of work on inorganic glasses. The second chapter discusses electron diffraction, one of the major methods of determining the structures of molecules in the gas phase. Chemists and molecular physicists will find the book a great source of information.

  • Reaction Kinetics

    Homogeneous Gas Reactions
    • 1st Edition
    • October 22, 2013
    • Keith J. Laidler
    • Robert Robinson + 2 more
    • English
    Reactions Kinetics: Volume I: Homogeneous Gas Reactions presents a general introduction to the subject of kinetics, including the basic laws of kinetics and the theoretical treatment of reaction rates. This four-chapter book deals mainly with homogeneous reactions in the gas phase. Chapter 1 presents the kinetic laws based on experimental results in terms of their simple concepts, with a special consideration of the way in which rates depend on concentration, while Chapter 2 deals with the interpretation of rates in terms of more fundamental theories. Chapter 3 covers the overall reactions that are believed to be elementary, such as the reaction between hydrogen and iodine, the reverse decomposition of hydrogen iodide, the corresponding reactions involving deuterium instead of hydrogen, and the dimerizations of butadiene and cyclopentadiene, as well as a few elementary termolecular reactions, all involving nitric oxide. This chapter also includes a general account of some of the elementary reactions that occur as steps in more complex mechanisms. Chapter 4 examines the reaction rates of numerous complex gas reactions. Undergraduate physical chemistry and chemical kinetics students, as well as advanced students in other fields, such as biology and physics, will find this book invaluable.

  • R.B. Woodward Remembered

    A Collection of Papers in Honour of Robert Burns Woodward 1917-1979
    • 1st Edition
    • October 22, 2013
    • D.H.R. Barton
    • English
    R.B. Woodward, Professor of Science at Harvard University, who died in July 1979, was generally considered to be the greatest organic chemist of modern times. He was one of the founders of Tetrahedron and Tetrahedron Letters and this volume, containing papers from over 50 of the world's leading organic chemists, is dedicated to his memory. The contents cover all areas of modern organic chemistry and therefore present a synopsis of current research in this area of science.

  • The Principles of Heterocyclic Chemistry

    • 1st Edition
    • October 22, 2013
    • Alan R. Katritzky + 1 more
    • English
    The Principles of Heterocyclic Chemistry presents a unified account of fundamental heterocyclic chemistry with the emphasis placed on the correlations between the methods of preparation and the properties of the various ring systems. This book opens with an introductory chapter that discusses fundamenta... concepts of the electronic theory of organic chemistry and the relationship of heterocyclic and carbocyclic aromatic compounds. This is followed by separate chapters on the chemistry of the six-membered ring compounds containing one or more heteroatoms, five-membered ring compounds, three- and four-membered rings, and the physical properties of representative heterocyclic compounds. Each chapter begins with introductory section that surveys the various ring types, gives the systems of nomenclature and numbering, and mentions a few important natural and synthetic compounds. Syntheses starting from aliphatic and carbocyclic compounds are then given. The preparation of one heterocyclic compound from another is considered as a reaction of the starting material. The reactions of aromatic and non-aromatic compounds are discussed separately. This book contains the essential heterocyclic chemistry required by an Undergraduate or Graduate student for his course-work, and it is hoped that it will be found stimulating by many a more senior teacher and researcher.

  • Chemical Induction of Cancer

    Structural Bases and Biological Mechanisms
    • 1st Edition
    • October 22, 2013
    • Joseph C. Arcos + 2 more
    • English
    Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume I discusses the role of chemicals in the genesis of cancer in man. This book is organized into two parts encompassing four chapters that also present the concepts and techniques of testing chemicals for carcinogenic potential. After an introduction to the distinctions between normal and neoplastic cells, this book goes on describing the structure of potential carcinogens, including alkanes, alkenes, alkynes, and aromatic hydrocarbons. The next chapter deals with the role of intra- and intermolecular forces of chemicals in their carcinogenic activity. The last chapter discusses some aspects of the pathology of chemically-induced tumors. This chapter also provides the concept and testing procedures of animal assays. This book is of great value to oncologists, pathologists, and general medical practitioners.

  • Synthesis of Pesticides Chemical Structure and Biological Activity Natural Products with Biological Activity

    Symposia Papers Presented at the Fourth International Congress of Pesticide Chemistry, Zurich, Switzerland, July 24-28, 1978
    • 1st Edition
    • October 22, 2013
    • H. Geissbühler + 2 more
    • English
    Advances in Pesticide Science, Part 2: Synthesis of Pesticides, Chemical Structure and Biological Activity, Natural Products with Biological Activity is a collection of papers presented at the Fourth International Congress of Pesticide Chemistry, held in Zurich, Switzerland on July 24-28, 1978. This book is composed of forty eight chapters, and begins with the synthesis of pesticides. The succeeding chapters deal with heterocyclic synthesis by rearrangement, synthesis and transformations of nitrogen and sulphurcontaining bicyclic heterocyclic systems. These topics are followed by discussions on synthesis of bmc-analogous n-heterocycles from 1,2-, 1,3-, 1,4-, and 1,5- diamines. Other chapters describe the synthesis and herbicidal activity of 4-acylpyrazole derivatives, the synthesis and properties of plant growth regulators, the carboxyphenyl derivatives of five and six membered heterocycles and potential phosphorus-containin... intermediates for the synthesis of pesticides. The final chapters consider the influence of antagonistic fungi on the spore-formation of rust fungi. This book will prove useful to agriculturists and organic chemists.

  • Pesticide Chemistry: Human Welfare and the Environment

    Pesticide Residues and Formulation Chemistry
    • 1st Edition
    • October 22, 2013
    • J. Miyamoto + 2 more
    • English
    Pesticide Chemistry: Human Welfare and the Environment, Volume 4: Pesticide Residues and Formulation Chemistry covers the proceedings of the Fifth International Congress of Pesticide Chemistry. The book covers research topics that tackle both improved agricultural production and public health concerns. The papers presented in this volume are organized into two parts. The first part tackles pesticide residues and methodology, which includes analysis of xenobiotics in air; pesticides residues in soil and water; and schematic flow diagram for pesticide analysis. The second part covers formulation chemistry, such as formation of drift and basic considerations for its reduction; the effects of adjuvants on biological activity of herbicides; and effect of formulation on vapor transfer. The book will be of great interest to professionals and researchers whose work involves pesticides.

  • Introduction to Clinical Oncology

    • 1st Edition
    • October 22, 2013
    • Stanley T. Crooke + 1 more
    • English
    9780121978020 Cancer and Chemotherapy, Volume II: Introduction to Clinical Oncology provides the basic framework for understanding antineoplastic drugs. The use of chemotherapeutics in the treatment of the most common human malignancies, including leukemias and lymphomas, is discussed. Solid tumors such as those affecting the breast and lung, head and neck, brain and spinal cord are also considered. Comprised of 17 chapters, this volume begins with an overview of leukemias and lymphomas, including their incidence, pathology, and clinical features. The discussion then turns to solid tumors such as breast and lung carcinoma; head and neck cancers; cancer of the brain and spinal cord; gastrointestinal, genitourinary, and gynecological cancers; and malignant melanoma. The next section is devoted to nutritional and infectious disease aspects of cancer and examines infections that arise in the cancer patient, particularly pneumonia and septicemia. The diagnosis of and therapy for these infections are outlined, along with granulocyte transfusion and prophylaxis of infection. The final chapter deals with nutrition in cancer patients and describes the link between cancer and malnutrition as well as the mechanisms of cancer-associated malnutrition. The advantages and methods of nutritional support for cancer patients are also highlighted. This book should be a valuable resource for oncologists.

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