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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske + 1 more
    • English
    The Alkaloids: Chemistry and Physiology, Volume II focuses on strychnine and morphine alkaloids. This book discusses the elucidation of the structure of morphine, codeine, and thebaine; synthetic hydrophenanthrenes related to the morphine alkaloids; and stereochemistry of the morphine alkaloids and sinomenine. The elucidation of the constitution of sinomenine, biological effects of colchicine, chemistry of individual alkaloids, and alkaloids of gelsemium species are also elaborated. This text likewise covers the isolation of the alkaloids, phenanthrene nucleus of morphine, fission around the nitrogen atom, and synthetic hydrophenanthrenes related to the morphine alkaloids. This volume is useful to chemists and researchers conducting work on alkaloid chemistry.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske
    • English
    The Alkaloids: Chemistry and Physiology, Volume IX focuses on alkaloid chemistry. This book discusses the occurence of known aporphines in plants, reductions with sodium in liquid ammonia, alkaloids related to corydaline, and quaternary alkaloids containing an N-methyl group. The phthalideisoquinolin... alkaloids, alkaloids containing one diphenyl ether linkage, trisisobutylisoquino... alkaloids, and alkaloids of Platydesma campanulata are also elaborated. This publication likewise covers the stereochemistry of the ring nitrogen in the tropanes, pharmacologically active synthetic tropanium salts, and alkaloids of apocynaceae. Other topics include the isolation and purification of salamandra alkaloids, biological activity of tylophora alkaloids, and structure of himbosine. This volume is valuable to chemists and researchers interested in alkaloids and their structures.

  • Theory of Dispersed Multiphase Flow

    Proceedings of an Advanced Seminar Conducted by the Mathematics Research Center The University of Wisconsin-Madison May 26-28, 1982
    • 1st Edition
    • Richard E. Meyer
    • English
    Mathematics Research Center Symposium: Theory of Dispersed Multiphase Flow covers the proceedings of an advanced seminar conducted by the Mathematics Research Center of the University of Wisconsin-Madison on May 26-28, 1982. The book focuses on solutions of long chain polymers in liquids, magnetic control of particle suspensions in fluid streams, aerosols, dense granular flows, and ice crystals or vapor bubbles dispersed in river waters. The selection first elaborates on the effects of interactions between particles on the rheology of dispersions; rheology of concentrated macromolecular solutions; and a survey of results in the mathematical theory of fluidization. Discussions focus on Rayleigh-Taylor instabilities, linear instability theory, steady solutions, general theory for polymer solutions and suspensions, electrostatically concentrated suspensions, and pair interaction theories. The text then examines instability in settling of suspensions due to Brownian effects; enhanced sedimentation in vessels having inclined walls; and simple kinetic theory of Brownian diffusion in vapors and aerosols. The text takes a look at the simulation of aerosol dynamics, continuum modeling of two-phase flows, multiphase mixture theory for fluid-particle flows, and mixture theory for turbulent diffusion of heavy particles. Topics include plane gravity flow, decomposition and averaging, isothermal flows of dilute suspensions, kinematics and the equations of motion, diffusional regularization, kinematic waves, and aerosol formation and growth in uniform systems. The selection is a valuable source of data for researchers interested in the theory of dispersed multiphase flow.

  • Small Molecular Immunomodifiers of Microbial Origin

    Fundamental and Clinical Studies of Bestatin
    • 1st Edition
    • Hamao Umezawa
    • English
    Small Molecular Immunomodifiers of Microbial Origin: Fundamental and Clinical Studies of Bestatin focuses on the results of experimental and clinical studies suggesting that bestatin and small molecular weight immunity-enhancing agents can contribute to the treatment of cancer and resistant infections. The selection first offers information on the screening, discoveries, and genetics of microbial secondary metabolites and activity of bestatin. Topics include the effect of bestatin on colony formation of murine bone marrow progenitor cells in vitro; antitumor effect of bestatin on murine transplantable tumors; and structures and properties of bestatin, amastatin, forphenicine, and esterastin. The text then examines the effects of bestatin on DNA and RNA metabolism in T-cells and levamisole and bestatin in immunodefficient aged mice. The text examines the influence of bestatin on the lymphoid system in humans, natural killer activity, and bone marrow. The preliminary phase I study of bestatin in lung cancer cases and malignant skin tumors are discussed. Topics include dosage schedule, clinical findings, and changes in immunological parameters. The selection is a vital reference for readers interested in the applications of bestatin in the treatment of cancer and resistant infections.

  • Handbook of Solvents

    Volume 1: Properties
    • 2nd Edition
    • George Wypych
    • English
    Each chapter in this volume is focused on a specific set of solvent properties which determine its choice, effect on properties of solutes and solutions, properties of different groups of solvents and the summary of their applications' effect. This includes effects on health and environment (given in tabulated form), swelling of solids in solvents, solvent diffusion and drying processes, nature of interaction of solvent and solute in solutions, acid-base interactions, effect of solvents on spectral and other electronic properties of solutions, effect of solvents on rheology of solution, aggregation of solutes, permeability, molecular structure, crystallinity, configuration, and conformation of dissolved high molecular weight compounds, methods of application of solvent mixtures to enhance the range of their applicability, and effect of solvents on chemical reactions and reactivity of dissolved substances.

  • Fundamental Aliphatic Chemistry

    Organic Chemistry for General Degree Students
    • 1st Edition
    • P. W. G. Smith + 1 more
    • English
    Organic Chemistry for General Degree Students is written to meet the requirements of the London General Internal examination and degree examinations of a similar standing. It will also provide for the needs of students taking the Part 1 examination for Graduate Membership of the Royal Institute of Chemistry, or the Higher National Certificate, whilst the treatment is such that Ordinary National Certificate courses can be based on the first two volumes Within the limits broadly defined by the syllabus, the aim of this first volume is to provide a concise summary of the important general methods of preparation and properties of the main classes of aliphatic compounds. Due attention is paid to practical considerations with particular reference to important industrial processes. At the same time, the fundamental theoretical principles of organic chemistry are illustrated by the discussion of a selection of the more important reaction mechanisms. Questions and problems are included, designed to test the student’s appreciation of the subject and his ability to apply the principles embodied therein. A selection of questions set in the relevant examinations is also included.

  • Synthetic Analgesics

    Diphenylpropylamines
    • 1st Edition
    • Paul A. J. Janssen
    • D. H. R. Barton + 1 more
    • English
    Synthetic Analgesics, Part I: Diphenylpropylamines deals with the methods of synthesis, the physical and chemical properties, and the ""analgesic"" activity of diphenylpropylamines... Topics covered include the ""analgesic"" activity of methadone, morphine, pethidine, and codeine in animals; diamines and derivatives; R875 and related basic tertiary amides; esters derived from amino acids and secondary and tertiary alcohols; and ketimines, acyl ketimines, and ketones. This book is comprised of 21 chapters and begins with a brief background on the first chemical and pharmacological experiments on diphenylpropylamines... followed by a discussion on ""analgesic"" activity in humans and animals. The ""analgesic"" activity of methadone, morphine, pethidine, and codeine in animals is considered. The following chapters explore a variety of compounds such as 3:3-diphenylpropylam... tertiary alcohols, secondary alcohols, primary alcohols, nitriles, diamines and derivatives, primary and secondary amides, acids and acid chlorides, and aldehydes. Sulfones, dissociation constants, and configurational studies are also described. This monograph will be a useful resource for researchers and practitioners in the fields of organic chemistry, analytical chemistry, and pharmacology.

  • Synthetic Analgesics

    Morphinans: Benzomorphans
    • 1st Edition
    • J. Hellerbach + 2 more
    • D. H. R. Barton + 1 more
    • English
    Synthetic Analgesics provides a comprehensive discussion of morphinans and 6,7-benzomorphans. Morphinans belong to a class of compounds possessing the main structural skeleton of morphine. Chemists have attempted to modify the morphine molecule in order to obtain analgesics without side-effects and addictive properties. The book is organized into two parts. Part A discusses the chemistry and pharmacology of morphinans, covering the syntheses of analgesics with morphine-like activity, N-methyl-morphinan, 3-hydroxy-N-methyl-m... and analogous compounds, toxicity and analgesic action of morphinan, and morphinans with anti-morphine activity. Part B deals with the chemistry and pharmacology of 6,7-benzomorphans; and opiate antagonists in the benzomorphan series.

  • The Isoquinoline Alkaloids

    A Course in Organic Chemistry
    • 1st Edition
    • K. W. Bentley
    • Robert Robinson
    • English
    The Isoquinoline Alkaloids: A Course in Organic Chemistry is a description of the chemical structures of alkaloids. The book discusses the processes for degradation of isoquinoline alkaloids to recognizable compounds such as oxidation and exhaustive methylation. The associated processes in removing the nitrogen atom are also explained. The commonly used Hofmann process and the interpretation of its result are evaluated in the degradation of alkaloids. The cactus ""pellote"" used by Mexican Indians to induce hallucinatory experiences is examined. The active ingredient is identified as mescaline; its composition is analyzed to contain one primary amino and three methoxyl groups. The different syntheses made to duplicate mescaline are described. The structures of morphine, codeine, and thebain, which are all alkaloids of opium, are also analyzed. Another example of a principal alkaloid found in a plant is emetine found in the root of the ipecac. The pharmacological bases of emetine are isolated and noted as emetamine, cephaeline, psychotrine, and O-methylpsychotrine. The text also traces many other structural relationships within the subgroups of the isoquinoline alkaloids. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology will find this book informative.

  • Aromatic Chemistry

    Organic Chemistry for General Degree Students
    • 1st Edition
    • P. W. G. Smith + 1 more
    • English
    Organic Chemistry for General Degree Students, Volume 2: Aromatic Chemistry covers the simple heteroaromatic systems and the chemistry of their functional groups. This book is divided into 11 chapters that also describe the properties of the aromatic compounds. The first chapters discuss the benzene structure and reactivity; nitro compounds and aromatic nitration; aromatic and side-chain halogenated compounds; general properties of aromatic sulfonic acids; and the mechanism of sulfonation. The succeeding chapters explore the analysis and general reactions of nucleophilic replacements, as well as the synthesis of sulfonic acid derivatives. These topics are followed by discussions on the basic properties of phenols and the reactions involving hydroxyl group. The last chapters examine the behavior of diazonium and the preparation of benzaldehyde. The book can provide useful information to scientists, chemists, students, and researchers.

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