Skip to main content
Elsevier

Books in Life sciences

  • Chemical Microbiology

    An Introduction to Microbial Physiology
    • 3rd Edition
    • A. H. Rose
    • English
    Chemical Microbiology: An Introduction to Microbial Physiology, Third Edition covers aspects of the chemical activities of microorganisms. The book describes the molecular architecture of microorganisms, the methods used in studying this molecular architecture; and the ways by which microorganisms can respond to and modify their environment. The text also discusses the various environmental factors that influence microbial activity. The book tackles the principles, the strategies employed, and the methods used in the studies of microbial metabolism. The transport of compounds into and out of microorganisms by the solute-transport processes and endocytosis; the principles of bioenergetics and biosynthesis; and the regulation of metabolism are also considered. The book tackles as well the growth, survival and differentiation of microorganisms. Biologists, microbiologists, chemical microbiologists, geneticists, and biochemists will find this book invaluable.

  • Steroid–Cell Interactions

    • 1st Edition
    • R. J. B. King + 1 more
    • English
    Steroid–Cell Interactions describes the processes involved in the intracellular binding of steroids (and related compounds) in mammalian cells. Serum binding proteins and steroid-immunoglobul... interaction are also discussed, along with the relationship of these binding processes to the biological action of the steroid. This book consists of 10 chapters and begins by presenting an elementary account of the factors contributing to the interaction between a steroid hormone and another molecule. The discussion then turns to the three types of methods used to study the interaction between steroids and tissue receptors: cell fractionation, autoradiography, and the separation of specifically and non-specifically bound steroids. The next chapter deals with the metabolism of steroid hormones in relation to their binding and mechanism of action, focusing on testosterone and progesterone. The reader is also introduced to the intracellular binding of androgens, glucocorticoids, mineralocorticoids, and estrogens and to how binding is related to biological activity. The final chapter reviews the clinical and immunological data relevant to steroid-protein binding. This text will be of interest to students and practitioners of biology, biochemistry, and physiology.

  • Guide des analyses en immunologie

    Indications, critères de réalisation et limites
    • 1st Edition
    • Collège des Enseignants d'Immunologie
    • French
    Ce guide, rédigé par l'ASSIM recense les principales analyses en immunologie prises en charge par la Sécurité sociale dans le cadre de la Nomenclature des Actes de Biologie Médicale (NABM).L'ouvrage développe en 6 grandes parties l'exploration : - de l'auto-immunité ; - de l'immunité humorale ; - de l'immunité cellulaire ; - en histocompatibilité et l'étude des associations HLA-maladies ; - des traitements par biomédicaments immunologiques. Chacune de ces parties est détaillée de façon pratique et synthétique sous forme de fiches, étayées de synopsis d'aide à l'exploration de la pathologie. Les points suivants sont systématiquement abordés : - la signification biologique du paramètre ; - les objectifs de l'analyse ; - la place de cette analyse dans un bilan d'exploration ; - la nature du prélèvement ; - les recommandations particulières ; - les contraintes d'acheminement ; - le mode de conservation ; - le principe méthodologique ; - le type de méthode et de mesure ; - le contrôle interne et l'évaluation externe de la qualité ; - les performances du test ; - les causes d'erreur et les limites du test.

  • Nuclear Pore Complexes and Nucleocytoplasmic Transport - Methods

    • 1st Edition
    • Volume 122
    • English
    Volume 122 of Methods in Cell Biology describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (including mammalian cells, Xenopus, C. elegans, yeast). The volume enables investigators to analyze nuclear pore complex structure, assembly, and dynamics; to evaluate protein and RNA trafficking through the nuclear envelope; and to design in vivo or in vitro assays appropriate to their research needs. Beyond the study of nuclear pores and transport as such, these protocols will also be helpful to scientists characterizing gene regulation, signal transduction, cell cycle, viral infections, or aging. The NPC being one of the largest multiprotein complexes in the cell, some protocols will also be of interest for people currently characterizing other macromolecular assemblies. This book is thus designed for laboratory use by graduate students, technicians, and researchers in many molecular and cellular disciplines.

  • General Immunology

    • 1st Edition
    • Edwin L. Cooper
    • English
    General Immunology provides a general overview of the immune system. It presents topics in immunology from all living groups, treating cells, tissues, organs, and organismal levels of biological organization. The book contains 23 chapters organized into eight sections. Section I serves as an introduction to immunology—a science, a sketch of its history, some of its more recent contributors, something about gathering facts, immunology journals, and the entire biomedical enterprise of which immunology is just a part. Section II is devoted to antigens while Section III examines the immune system in chordates and the ontogeny of the immune system. Section IV on cells of the immune system covers monocytes, macrophages, the three granulocytic types, and mast cells. Section V deals with phagocytosis and the interaction of lymphocytes. Section VI is devoted to antigens in relation to antibody synthesis, antigen-antibody interactions, immunologlobulin structure, and immunologlobulin assembly. Section VII on organs of the immune system examines bone marrow, thymus, spleen, lymph nodes, and lymphoid aggregations. Section VIII discusses the evolution of the immune system. This text was written for advanced undergraduates. However, its comprehensiveness makes it useful to immunologists and biologists at all levels as well as medical students and clinicians.

  • The Shikimate Pathway

    Biosynthesis of Natural Products Series
    • 1st Edition
    • Edwin Haslam
    • Gordon Kirby
    • English
    The Shikimate Pathway gives a bird's eye view of the shikimate pathway and its implications for the life of a range of organisms. Topics covered in this book include the chemistry of intermediates in the shikimate pathway; biosynthesis of aromatic amino acids in this pathway; its metabolites; and its role in higher plants. This book is comprised of six chapters and begins by introducing the reader to shikimic acid, a natural product derived from the plant Illicium religiosum, along with the mechanistic and stereochemical aspects of the reactions of the shikimate pathway. The biosynthesis of aromatic amino acids from chorismate is also described, and then the discussion turns to the chemical properties and the detailed stereochemistry of intermediates and enzymes in the shikimate pathway. The next chapter examines the biosynthesis of isoprenoid quinones involved in electron transport and the folic acid group of co-enzymes in the shikimate pathway. The metabolism of the aromatic amino acids in microorganisms and higher organisms is considered, along with the biosynthesis and physiological functions of phenylpropanoid compounds and their derivatives in the shikimate pathway in higher plants. This book will be of general value to practitioners in the many and varied areas of biochemical research associated with metabolism.

  • Mammalian Cell Membranes

    Volume 2: The Diversity of Membranes
    • 1st Edition
    • G. A. Jamieson + 1 more
    • English
    Mammalian Cell Membranes, Volume Two: The Diversity of Membranes is a collection of reviews focusing on to specific types of intra- and extracellular membranes. The compendium contains 10 contributions devoted to the review of mammalian cell membranes. The topics covered in the book include the organization of the plasma membrane of mammalian cells, membranes of the endoplasmic reticulum and the secretory system and their role in plasma membrane regulation, and the structure of mitochondrial membranes. The nuclear envelope in mammalian cells, the myelin sheath, and the microvilli and cilia are also discussed. Cytologists, molecular biologists, biochemists, and anatomists will find the book very useful.

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Seventh Colloquium, 1979
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids reviews trends in research concerning protides of the biological fluids, with emphasis on tumor-associated antigens (TAAs), lectins, and separation methods such as electrophoresis and isoelectric focusing. Examples of TAAs discussed in this book are carcinoembryonic antigens, mesenchyme-associate... antigens, and oncofetal pancreatic antigens. The mode of action of lectins as well as lectin-binding sites are also considered. This book is comprised of 195 chapters and begins with an overview of the strategy and monitoring of protein fractionation, followed by a discussion on the self-nonself concept of cancer and ""autoimmune"" diseases; presence of trophoblast antigens on the membranes of some human tumor and transformed cells; and non-specific cross-reacting antigens in human blood monocytes. Subsequent chapters explore the metabolism of carcinoembryonic antigen and alpha-fetoprotein during delivery; amino acid sequence identity of tissue polypeptide antigen fragments from different sources; isoferritins, glycoproteins, and viral antigens; and crossed immunoelectrophoresi... of yeast plasma membrane lectin receptors. The final section is devoted to separation techniques such as isotachophoresis, chromatography, electrophoresis, and isoelectric focusing. This monograph will be of value to biologists and researchers interested in protides of the biological fluids.

  • All Heal

    A Medical and Social Miscellany
    • 1st Edition
    • R M Shaw + 2 more
    • English
    All Heal contains a selection of the articles of more general interest that were published in The Proceedings of the Royal Society of Medicine since 1957. The editors have chosen no more than one paper from any individual author. This book features 17 medical and social miscellany articles. The topics covered by these papers include the evolution on teaching-hospital physicians in Great Britain, the relation between crime and the British penal system, the conflict between drug control and therapeutic freedom and the academic and economic freedom of British universities. This book will be of interest to persons dealing with studies on medical and social history of Great Britain since1957.

  • Immunological Aspects of Reproduction in Mammals

    • 1st Edition
    • D. B. Crighton
    • English
    Immunological Aspects of Reproduction in Mammals contains papers presented during a symposium at the University of Nottingham Easter School. The scholarly presentations provide a wealth of information on the field of reproductive immunology and indicate just how complex this field is and how many questions still remain to be answered. The book begins with reviews of the current status of the complexities and uncertainties of the cellular basis of the immune response and the structure and function of antibodies. This is followed by separate chapters on the assessment and interpretation of the phenomena surrounding autoimmune and isoimmune reactions to spermatozoa; advances in defining the distribution and degree of exposure of major histocompatibility antigens; the reproductive immunology of the mouse, horse, and sheep; and fetal and neonatal immunity. Subsequent chapters present studies of immunization of several species with either the hypothalamic hormone LH-RH, pituitary gonadotrophins, or ovarian steroids; and studies directed towards efforts to enhance animal production by either active or passive immunization of female farm animals against steroid hormones. This book will be a valuable reference text for those already involved in the field and a stimulus for others to enter this complex and fascinating area of research.

Related subjects