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    • Scientific Foundations of Biochemistry in Clinical Practice

      • 2nd Edition
      • April 24, 2014
      • David L. Williams + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 7 8 1 6
      • eBook
        9 7 8 1 4 8 3 1 9 3 6 2 5
      Scientific Foundations of Biochemistry in Clinical Practice, Second Edition describes the pathological aspects of general metabolic disorders. This book is organized into 10 sections encompassing 45 chapters that discuss the nature of disorders involving disturbance in hydrogen ion concentration and blood gases, as well as the disorders of fluid and electrolyte balance. Some of the topics covered in the book are the chemical analysis of urine; neonatal screening for biochemical disorders; clinical biochemistry of alcohol, in intensive and postoperative care; psychiatric disorders of biochemical origin; abnormalities of the plasma proteins; assessment of gastrointestinal function; and calcium metabolism. Other chapters examine the nature, conditions, and diagnosis of bone disorders. A chapter emphasizes the functions of hypothalamus and pituitary. Another chapter looks into the biochemistry and toxicology of metals. The final chapters are devoted to the classification of connective tissue diseases and to the examination of clinical biochemistry of the central nervous system. The book can provide useful information to doctors, biochemists, students, and researchers.

    • Neurovirology

      • 1st Edition
      • Volume 123
      • July 8, 2014
      • Alex C. Tselis + 1 more
      • English
      • eBook
        9 7 8 0 7 0 2 0 4 5 3 9 4
      This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology. Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.

    • Nanosensors for Chemical and Biological Applications

      • 1st Edition
      • February 12, 2014
      • Kevin C. Honeychurch
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 6 6 0 9
      • Paperback
        9 7 8 0 0 8 1 0 1 3 7 0 0
      • eBook
        9 7 8 0 8 5 7 0 9 6 7 2 2
      Nano-scale materials are proving attractive for a new generation of devices, due to their unique properties. They are used to create fast-responding sensors with good sensitivity and selectivity for the detection of chemical species and biological agents. Nanosensors for Chemical and Biological Applications provides an overview of developments brought about by the application of nanotechnology for both chemical and biological sensor development. Part one addresses electrochemical nanosensors and their applications for enhanced biomedical sensing, including blood glucose and trace metal ion analysis. Part two goes on to discuss spectrographic nanosensors, with chapters on the use of nanoparticle sensors for biochemical and environmental sensing and other techniques for detecting nanoparticles in the environment. Nanosensors for Chemical and Biological Applications serves as a standard reference for R&D managers in a range of industrial sectors, including nanotechnology, electronics, biotechnology, magnetic and optical materials, and sensors technology, as well as researchers and academics with an interest in these fields.

    • Immunological and Blood Products

      • 1st Edition
      • May 12, 2014
      • Mary Dawson + 1 more
      • J. B. Stenlake
      • English
      • Paperback
        9 7 8 1 4 8 3 1 8 0 3 0 4
      • eBook
        9 7 8 1 4 8 3 1 9 6 1 1 4
      Pharmaceutical Monographs, Volume 5: Immunological and Blood Products provides an introduction to immunology and immunological products. This monograph describes various tissue culture techniques, which are important both in the preparation and standardization of certain immunological products. Organized into two parts encompassing 13 chapters, this volume begins with an overview of the types of immunity. This text then examines the substances which when introduced parenterally into the tissues, stimulates the production of an antibody. Other chapters consider antibodies as substances appearing in the blood or body fluids in response to the stimulus provided by the introduction of an antigen. This monograph discusses as well the preparations capable of stimulating active immunity. The final chapter deals with the causation of hemolytic disease of the newborn. This monograph is a valuable resource for medical students as well as undergraduate students of pharmacy. Students of veterinary medicine will also find this book extremely useful.

    • Handbook on the Toxicology of Metals

      • 4th Edition
      • August 7, 2014
      • Gunnar F. Nordberg + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 9 4 5 3 2
      • eBook
        9 7 8 0 1 2 3 9 7 3 3 9 9
      Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth edition also contains several new chapters on important topics such as nanotoxicology, metals in prosthetics and dental implants, gene-environment interaction, neurotoxicology, metals in food, renal, cardiovascular, and diabetes effects of metal exposures and more. Volume I covers “General Considerations” and Volume II is devoted to “Specific Metals.” A multidisciplinary resource with contributions from internationally-reco... experts, the fourth edition of the Handbook on the Toxicology of Metals is a prominent and indispensable reference for toxicologists, physicians, pharmacologists, engineers, and all those involved in the toxicity of metals.

    • Calcium Physiology

      • 1st Edition
      • May 12, 2014
      • C. L. Comar + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 5 9 8 2 6
      Mineral Metabolism, Volume III: Calcium Physiology focuses on the processes, reactions, and approaches involved in calcium metabolism and study of bones. The selection first underscores the measurements and models of skeletal metabolism and advances in the physical biology of bone and other hard tissues, including measurements and concepts, composition and structure of bone minerals, and dynamic studies of bone minerals. The text then takes a look at calcium and striated muscle and renal excretion of alkaline earths. Topics include physicochemical state of alkaline earth cations in plasma and urine, effects of drugs, renal diseases, calcium and contractile proteins, resting potential and action potential, calcium and muscle contraction, and coupling of excitation and energy synthesis. The book examines the aspects of intestinal absorption of calcium, with special reference to vitamin D, as well as the physiological mechanism of the intestinal absorption of calcium; effect of other nutritional and physiological factors on calcium absorption; and structure of the intestinal epithelial cell. The selection is a dependable source material for physiologists and readers interested to pursue research on calcium physiology.

    • Neurologic Aspects of Systemic Disease, Part III

      • 1st Edition
      • Volume 121
      • January 9, 2014
      • Jose Biller + 1 more
      • English
      • Hardback
        9 7 8 0 7 0 2 0 4 0 8 8 7
      • eBook
        9 7 8 0 7 0 2 0 4 4 3 4 2
      Systemic disease involves several parts of the body or the complete system. This comprehensive reference focuses on the specific neurologic aspects of systemic disease. Part 3 includes coverage of oncologic disorders, organ transplantation, infectious diseases, tropical neurology, pregnancy, neuroanesthesia and other diseases and disorders. Each chapter provides a complete introduction to the neurologic aspect and provides the best known diagnostic and treatment practices. The collection will be a valuable and trusted resource for clinical neurologists, research neurologists and neuroscientists and general medical professionals as a first stop for a comprehensive and focused review of the state of the art for understanding the neurologic impact of each covered disease.

    • Starch Polymers

      • 1st Edition
      • March 8, 2014
      • P. Halley + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 3 7 3 0 0
      • eBook
        9 7 8 0 4 4 4 5 3 7 3 1 7
      This book focuses on starch polymers including starch genetics, biotechnological and chemical modification, nanostructures, processing, characterization, properties and applications. This books topic is in a cutting edge and emerging technology area of biomaterials, nanomaterials and renewable materials, and will involve international experts in diverse fields from genetic engineering to applications.

    • Gel Electrophoresis of Proteins

      • 1st Edition
      • May 12, 2014
      • Michael J Dunn
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 7 7 3 1
      • eBook
        9 7 8 1 4 8 3 1 9 3 5 4 0
      Gel Electrophoresis of Proteins focuses on the techniques, methodologies, reactions, and approaches involved in gel electrophoresis of proteins. The selection first covers steady-state gel electrophoresis systems and one-dimensional PAA-gel electrophoretic techniques to separate functional and denatured proteins. Discussions focus on affinity electrophoresis, structure and physico-chemical properties of polyacrylamide gels, moving boundary electrophoresis, isotachophoresis, fundamental steady-state electrophoresis systems, and fundamental properties of steady-state electrophoresis systems. The text then reviews conventional isoelectric focusing and immobilized pH gradients and high resolution two-dimensional polyacrylamide-gel electrophoresis. Topics include production of narrow pH gradients, extended pH gradients, polymerization kinetics, IEF in agarose matrices, titration curves, two-dimensional electrophoresis under non-denaturing conditions, and IEF in polyacrylamide matrices. The book tackles quantifying patterns from two-dimensional PAGE, protein staining and detection methods, and immunoelectrophoreti... methods. Concerns include post-electrophoretic organic protein stains, silver and enzyme stains, detection of radioactive proteins, and programming languages. The selection is highly recommended for researchers wanting to conduct studies on gel electrophoresis of proteins.

    • Human Herpesviruses HHV-6A, HHV-6B and HHV-7

      • 3rd Edition
      • Volume 12
      • February 11, 2014
      • Louis Flamand + 3 more
      • English
      • Hardback
        9 7 8 0 4 4 4 6 2 7 0 3 2
      • eBook
        9 7 8 0 4 4 4 6 2 7 1 6 2
      Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases.

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