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Books in Life sciences

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    • Biomechanics of the Female Pelvic Floor

      • 1st Edition
      • Lennox Hoyte + 1 more
      • English
      Biomechanics of the Female Pelvic Floor, Second Edition, is the first book to specifically focus on this key part of women’s health, combining engineering and clinical expertise. This edited collection will help readers understand the risk factors for pelvic floor dysfunction, the mechanisms of childbirth related injury, and how to design intrapartum preventative strategies, optimal repair techniques, and prostheses. The authors have combined their expertise to create a thorough, comprehensive view of female pelvic floor biomechanics in order to help different disciplines discuss, research, and drive solutions to pressing problems. The book includes a common language for the design, conduct, and reporting of research studies in female PFD, and will be of interest to biomechanical and prosthetic tissue engineers and clinicians interested in female pelvic floor dysfunction, including urologists, urogynecologists, maternal fetal medicine specialists, and physical therapists.

    • Advances in Food and Nutrition Research

      • 1st Edition
      • Volume 77
      • English
      Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences, bringing together outstanding and comprehensive reviews that highlight this relationship. The book contains contributions that detail scientific developments in the broad areas of food science and nutrition, providing those in academia and industry with the latest information on emerging research in these constantly evolving sciences.

    • G Protein-Coupled Receptors

      Signaling, Trafficking and Regulation
      • 1st Edition
      • Volume 132
      • English
      G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation.

    • Profiles of Drug Substances, Excipients and Related Methodology

      • 1st Edition
      • Volume 41
      • English
      Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

    • The Cytology of Effusions

      Pleural, Pericardial and Peritoneal and of Cerebrospinal Fluid
      • 2nd Edition
      • A. I. Spriggs + 1 more
      • English
      The Cytology of Effusions: Pleural, Pericardial and Peritoneal and of Cerebrospinal Fluid, Second Edition provides information pertinent to the cytology of effusion in various conditions. This book discusses the cytology of cerebrospinal fluid wherein the appropriate methods for studying this material are much the same as for serous fluids. Organized into nine chapters, this edition begins with an overview of the differential cell count from a serous fluid. This text then presents the nomenclature and descriptions of cells of serous effusions. Other chapters consider the cytological examinations of pleural or peritoneal fluid, which often shed light on the diagnosis in leukemias and lymphomas. This book discusses as well the general features of malignant effusions that may suggest the diagnosis. The final chapter deals with the distinction between polymorphonuclear and lymphocytic types of meningeal exudate made from an examination of the cerebrospinal fluid. This book is a valuable resource for pathologists and clinicians.

    • Nonsense Mutation Correction in Human Diseases

      An Approach for Targeted Medicine
      • 1st Edition
      • Fabrice Lejeune + 2 more
      • English
      Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.

    • Nitric Oxide and Signaling in Plants

      • 1st Edition
      • Volume 77
      • English
      Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 77th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology.

    • Genes, Environment and Alzheimer's Disease

      • 1st Edition
      • Orly Lazarov + 1 more
      • English
      Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.

    • Tumor Immunology

      • 1st Edition
      • Volume 130
      • English
      Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on tumor immunology.

    • Epi-Informatics

      Discovery and Development of Small Molecule Epigenetic Drugs and Probes
      • 1st Edition
      • Jose Medina-Franco
      • English
      Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology