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Books in Life sciences

  • Protein Interactions as Targets in Drug Discovery

    • 1st Edition
    • Volume 121
    • April 17, 2020
    • Rossen Donev
    • English
    Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interactions. Chapters in this new release include Trends in structure based drug design with protein targets, From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD), Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis, Aromatic-aromatic interactions in protein-drug and protein-protein interactions, Role of protein-protein interaction in allosteric drug design within the human methyltransferome, and much more.
  • Practical Paediatric Prescribing

    How to Prescribe the Most Common Drugs
    • 1st Edition
    • April 16, 2020
    • Will Carroll + 4 more
    • English
    Prescribing for children is problematic. Children are not small adults in terms of their physiology, and they cannot be subjects in clinical trials. This makes prescribing for them something of an art and a daunting one at that for trainees. Will Carroll (co-editor of the Illustrated Textbook of Paediatrics amongst other titles for paediatrics trainees) with a team of fellow paediatricians and a hospital pharmacist have sought to demystify prescribing for children. The team has identified what from their experience are the most common drugs prescribed to children and have addressed each one, adding detail about how each medicine works. Each chapter follows the ABCDE structure covering Absorption, Biological effects, Clearance, Dosing and side Effects in children. This book is a succinct, portable reference, modelled closely on Hitchings et al.: The Top 100 Drugs.
  • Diabetes

    Oxidative Stress and Dietary Antioxidants
    • 2nd Edition
    • April 16, 2020
    • Victor R. Preedy
    • English
    Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer.
  • Personalized Computational Hemodynamics

    Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy
    • 1st Edition
    • April 16, 2020
    • Yuri Vassilevski + 4 more
    • English
    Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies.
  • Food Safety and Quality Systems in Developing Countries

    Volume III: Technical and Market Considerations
    • 1st Edition
    • April 15, 2020
    • André Gordon
    • English
    Food Safety and Quality Systems in Developing Countries: Volume III: Technical and Market Considerations is a practical resource for companies seeking to supply food products from developing countries to developed country markets or to transnational business located in developing countries. It explores practical approaches to complying with food safety and quality systems requirements, backed by the science-based approaches used in the major markets applied in a developing country context. It explores the topic from the perspective of agribusiness value chains and includes deconstructions of regulatory and market channel-specific technical requirements in North America, Europe, and other major markets. Volume III builds on the platforms laid by the previous two volumes, providing guidance from industry-leading experts on addressing regulatory and market-specific microbiological, chemical, packaging and labelling, supply chain, and systems-related food safety and quality compliance requirements. This book addresses technical and market-determined standards that value chain participants in developing countries face supplying developed country markets or transnational firms, including hotels, major multiples, and quick serve restaurant brands.
  • Tuberculous Meningitis

    Manual of Diagnosis and Therapy
    • 1st Edition
    • April 15, 2020
    • Jerome Chin
    • English
    Tuberculous Meningitis: Manual of Diagnosis and Therapy focuses on the most common and most lethal manifestation of tuberculosis of the central nervous system. It includes up-to-date reviews of the diagnosis, treatment, and management of tuberculous meningitis in adults and children. Extensive guidance is provided for the treatment of drug-sensitive and drug-resistant tuberculosis and tuberculous meningitis. Clinicians and researchers will find the beginning chapters on immunopathology and epidemiology of great use in their efforts to develop new strategies for the diagnosis and treatment of tuberculous meningitis.
  • Ethical Dimensions of Commercial and DIY Neurotechnologies

    • 1st Edition
    • Volume 3
    • April 12, 2020
    • English
    Ethical Dimensions of Commercial and DIY Neurotechnologies Volume Three, the latest release in the Developments in Neuroethics and Bioethics series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding neuroethics and bioethics. Each chapter is written by an international board of authors.
  • Advances in Parasitology

    • 1st Edition
    • Volume 108
    • April 11, 2020
    • David Rollinson + 1 more
    • English
    The Advances in Parasitology series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history, all topics which help to shape current thinking and applications. This latest release includes chapters on the discovery of selected compounds with anthelmintic activity against the barber’s pole worm – where to from now?, zoonotic transmission of intestinal parasites: implications for control and elimination, taenia asiatica with a historical overview of taeniasis and cysticercosis, advances on the use of automated image analysis of parasite larval assays, and much more.
  • Handbook of Clinical Adult Genetics and Genomics

    A Practice-Based Approach
    • 1st Edition
    • April 10, 2020
    • Shweta Dhar + 2 more
    • English
    Handbook of Clinical Adult Genetics and Genomics: A Practice-Based Approach provides a thorough overview of genetic disorders that are commonly encountered in adult populations and supports the full translation of adult genetic and genomic modalities into clinical practice. Expert chapter authors supplement foundational knowledge with case-based strategies for the evaluation and management of genetic disorders in each organ system and specialty area. Topics discussed include employing genetic testing technologies, reporting test results, genetic counseling for adult patients, medical genetics referrals, issues of complex inheritance, gene therapy, and diagnostic and treatment criteria for developmental, cardiovascular, gastrointestinal, neuropsychiatric, pulmonary issues, and much more.
  • Milk and Dairy Foods

    Their Functionality in Human Health and Disease
    • 1st Edition
    • April 8, 2020
    • Ian Givens
    • English
    Milk and Dairy Foods: Their Functionality in Human Health and Disease addresses issues at key life stages, presenting updates on the impact of dairy on cardiometabolic health, hemodynamics, cardiovascular health, glycemic control, body weight, bone development, muscle mass and cancer. The book also explores the impact of dairy fats on health, dairy fat composition, trans-fatty acids in dairy products, the impact of organic milk on health, milk and dairy intolerances, and dairy as a source of dietary iodine. Written for food and nutrition researchers, academic teachers, and health professionals, including clinicians and dietitians, this book is sure to be a welcomed resource for all who wish to understand more about the role of dairy in health.