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    • Combination Therapy Against Multidrug Resistance

      • 1st Edition
      • April 30, 2020
      • Mohmmad Younus Wani + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 5 7 6 1
      • eBook
        9 7 8 0 1 2 8 2 0 5 7 8 5
      Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant

    • Retinoid Signaling Pathways

      • 1st Edition
      • Volume 637
      • April 29, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 1 4 4 2
      • eBook
        9 7 8 0 1 2 8 2 0 1 4 7 3
      Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.

    • Immunological Methods in Microbiology

      • 1st Edition
      • Volume 47
      • April 29, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 8 1 1 3
      • eBook
        9 7 8 0 1 2 8 2 0 8 1 2 0
      Immunological Methods in Microbiology, Volume 47 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Immunological Techniques in the Clinical laboratory, Immunologic Diagnosis of HIV and Opportunistic Infections, Combining Antigen Detection and Serology for the Diagnosis of Selected Infectious Diseases, Immunologic Detection of Lyme Disease and Related Borrelioses, Immunodetection of Bacteria Causing Brucellosis, Immunological Diagnostic Techniques Used to Identify and Type Pasteurella, Immunological Tests for Diarrhea caused by Diarrheagenic Escherichia coli Targeting Their Main Virulence Factors, and much more.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 96
      • April 29, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 1 6 6 3
      • eBook
        9 7 8 0 1 2 8 2 1 1 7 0 0
      Advances in Clinical Chemistry, Volume 96, the latest installment in this acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest, most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory. Chapters in this release include Revisiting immune complexes: key to understanding immune-related diseases, New Biomarkers in Non-Hodgkin Lymphoma and Acute Leukemias, Omics and The Molecular Exercise Physiology, Neurotransmitter, neuropeptide and gut peptide profile in PCOS- pathways contributing to the pathophysiology, food intake and psychiatric manifestations of PCOS, and much more.

    • Automated Drug Delivery in Anesthesia

      • 1st Edition
      • April 29, 2020
      • Dana Copot
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 9 7 5 0
      • eBook
        9 7 8 0 1 2 8 1 5 9 7 6 7
      Automated Drug Delivery in Anesthesia provides a full review of available tools and methods on the drug delivery of anesthesia, bridging the gap between academic development, research and clinical practice. The book takes an interdisciplinary approach, pulling information about tools developed in other disciplines such as mathematics, physics, biology and system engineering and applying them to drug delivery. The book's authors discuss the missing element of complete regulatory loop of anesthesia: the sensor and model for pain pathway assessment. This is the only book which focuses specifically on the delivery of anesthesia.

    • Mitochondrial Disease Genes Compendium

      • 1st Edition
      • April 28, 2020
      • Marni J. Falk
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 0 2 9 2
      • eBook
        9 7 8 0 1 2 8 2 0 0 3 0 8
      The field of Mitochondrial Medicine has been dominated by symptom constellation-based diagnostic categorization since the first clinical syndrome was described three decades ago. Now, as rapidly expanding knowledge has revealed that mitochondrial diseases may result from several hundred distinct gene disorders with extensive clinical and mutation heterogeneity, the most useful guide for clinical care and research embraces a gene-centric approach to each individual’s disorder. Together with international colleagues, Dr. Marni Falk has developed the Mitochondrial Disease Sequence Data Resource (MSeqDR), an online, community curated, centralized data resource of mitochondrial disease data from a genomic perspective. Here, in the Mitochondrial Disease Genes Compendium, Dr. Marni Falk and a team of international experts have built off their work on MSeqDR to provide an all-in-one, readily accessible, and easy-to-use at point of care reference on 256 mitochondrial disease genes from a gene-based perspective. In this book, clinicians and researchers will find a complete overview of mitochondrial disease genes relevant across all specialties, cataloging and building context around clinical features and the genetic basis of each condition. Within, each "gene page" offers an in-depth, referenced view of the relevant clinical disease spectrum, including gene and protein descriptions, year discovered, inheritance pattern(s), age ranges affected, major clinical features and severity range, clinical pearls, known therapies, available support groups, animal models, and gene-specific basic, translational, or clinical research activities now underway. Links provided on each gene page direct readers to MSeqDR for new findings, up-to-date genomic variant data, and user friendly informatics tools accessible to general clinicians and sophisticated geneticists or bioinformaticians alike, ensuring access to updated information on each condition.

    • Food Safety Lessons for Cannabis-Infused Edibles

      • 1st Edition
      • April 28, 2020
      • Kathy Knutson
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 5 1 2 3
      • eBook
        9 7 8 0 1 2 8 1 9 5 3 7 6
      Food Safety Lessons for Cannabis-Infused Edibles details the world of cannabis-infused edibles and the way its manufacturing is evolving as the industry moves from isolation to regulatory compliance. The cannabis industry has unique challenges as cannabis-infused edibles are not regulated as food, drugs or dietary supplements at the federal level. Despite these current conditions, the industry is aware of the need to examine the safety of these edibles and prepare for a future of federal compliance. The book looks at the cannabis industry through a scientific lens to increase awareness and expertise in food safety within the field of cannabis-infused edibles.

    • Food Waste to Valuable Resources

      • 1st Edition
      • April 28, 2020
      • Rajesh Banu + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 3 5 3 3
      • eBook
        9 7 8 0 1 2 8 1 8 3 5 4 0
      Food Waste to Valuable Resources: Applications and Management compiles current information pertaining to food waste, placing particular emphasis on the themes of food waste management, biorefineries, valuable specialty products and technoeconomic analysis. Following its introduction, this book explores new valuable resource technologies, the bioeconomy, the technoeconomical evaluation of food-waste-based biorefineries, and the policies and regulations related to a food-waste-based economy. It is an ideal reference for researchers and industry professionals working in the areas of food waste valorization, food science and technology, food producers, policymakers and NGOs, environmental technologists, environmental engineers, and students studying environmental engineering, food science, and more.

    • Treatment of Movement Disorders, An Issue of Neurologic Clinics

      • 1st Edition
      • Volume 38-2
      • April 27, 2020
      • Joseph Jankovic
      • English
      • Hardback
        9 7 8 0 3 2 3 7 0 9 9 1 0
      • eBook
        9 7 8 0 3 2 3 7 0 9 9 2 7
      In collaboration with Consulting Editor, Randolph W. Evans, Dr. Joseph Jankovic has put together an issue of Neurologic Clinics devoted to Treatment of Movement Disorders. Topics include, but are not limited to, Clinical Rating Scales and Quantitative Assessments of Movement Disorders, Pharmacologic Treatment of Motor Symptoms Associated with Parkinson’s Disease, Treatment of Non-Motor Symptoms Associated with Parkinson’s Disease, Surgical Treatment of Parkinson’s Disease, Emerging Medical and Surgical Treatments of Essential Tremor, Medical and Surgical Treatments of Dystonia, Medical and Surgical Treatments of Tourette Syndrome, Medical, Genetic and Surgical Treatments of Huntington Disease, Treatment of Tardive Dyskinesia, Medical and Surgical Treatments of Cerebral Palsy, Treatment of Wilson Disease, Treatment of Paroxysmal Dyskinesias, Treatment of Ataxia, and Treatment of Functional (Psychogenic) Movement Disorders.

    • Dysimmune Neuropathies

      • 1st Edition
      • April 26, 2020
      • Yusuf Rajabally
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 5 7 2 2
      • eBook
        9 7 8 0 1 2 8 1 4 5 7 3 9
      Dysimmune Neuropathies provides readers with detailed, basic information that will enable users to recognize and differentiate each neuropathy to adequately guide an investigation and create a treatment plan. An overview of recent progress, avenues for future research, and the desired benefits are also covered. The book highlights the many developments in the field that have occurred in terms of pathophysiological mechanisms, particularly immunological, that have direct implications on treatment strategies. This book is a great reference for trainees, clinicians and researchers specializing in neurology, neuromuscular diseases and neurophysiology.

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