Heart and Neurologic Disease

1st Edition, Volume 177 - February 23, 2021
Editor: Jose Biller
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 1 9 8 1 4 - 8
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 0 3 8 9 - 7

The Handbook of Clinical Neurology series volumes provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. Cardiac d… Read more

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The Handbook of Clinical Neurology series volumes provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. Cardiac disorders and diseases may often co-occur with, or cause, subsequent neurological disorders. Heart and Neurologic Disease identifies the top cardiac diseases and disorders most likely to have neurological disorders, how they will present, and how they are best treated. It identifies the mechanisms of action explaining why the conditions co-occur, and what clinicians should look for symptom wise, and how risk may be assessed. Coverage includes genetic cardiac disorders, cardiac trauma, surgery, infection, disease, and arrhythmia.

Cover image
Title page
Table of Contents
Copyright
Handbook of Clinical Neurology 3rd Series
Foreword
Preface
Contributors
Chapter 1: Neurologic complications of pediatric congenital heart disease
Abstract
Vascular Complications of Pediatric Congenital Heart Disease
Infective Complications of Pediatric Congenital Heart Disease
Epilepsy and Pediatric Congenital Heart Disease
Neurodevelopmental Sequelae of Pediatric Congenital Heart Disease
Chapter 2: Neurologic complications of congenital heart disease in adults
Abstract
Introduction
Classification, Anatomy, and Clinical Presentation of Congenital Heart Disease
Cerebrovascular Complications of ACHD
Cognitive Impairment and Psychiatric Disease in ACHD
Epilepsy
Conclusion
Chapter 3: Neurologic complications of rheumatic fever
Abstract
Introduction
Historic Vignette
Epidemiology
Pathophysiology
Clinical Presentation
Diagnosis
Treatment
Prognosis
Conclusions
Chapter 4: Neurologic complications of nonrheumatic valvular heart disease
Abstract
Calcific Valve Disease
Mitral Valve Prolapse
Prosthetic Heart Valves
Anticoagulation and Its Complications
Lambl's Excrescences
Chapter 5: Advances and ongoing controversies in PFO closure and cryptogenic stroke
Abstract
Introduction
Diagnosis and Characterization of PFO
Diagnosis of Cryptogenic Stroke
PFO Closure vs Medical Treatment
Patient Selection
Conclusions
Chapter 6: Neurological complications of coronary heart disease and their management
Abstract
Introduction
Epidemiology
Etiology
Clinical Presentation, Diagnoses, and Management of Neurological Complications of Coronary Heart Disease
Conclusion
Chapter 7: Neurologic complications of heart surgery
Abstract
Introduction
Acute Ischemic Stroke
Other Types of Ischemic Complications
Hemorrhagic Stroke
Seizures
Cognitive Decline
Psychological Complications
Contrast Neurotoxicity
Peripheral Nerve Injuries
Chapter 8: Neurological complications of heart failure
Abstract
Introduction
Etiology of Heart Failure
Heart Failure and Atrial Fibrillation
Physiological Brain Changes in HF Patients
Neurological Complications Associated With Heart Failure
Chapter 9: Neurological complications of cardiomyopathies
Abstract
Definition, Classification and Clinical Update
Neurological Manifestations of Cardiomyopathies
Cerebrovascular Complications
Neuromuscular Disorders
Chapter 10: Neurologic complications of myocarditis
Abstract
Neurological Complications of Myocarditis
Myocarditis, General Principles
Diagnosis of Myocarditis
Covid-19 Myocarditis
Myocarditis and Myasthenia Gravis Associations
Conclusions and Future Directions
Chapter 11: Neurologic complications of infective endocarditis
Abstract
Introduction
Diagnosis of Infective Endocarditis
General Management of Infective Endocarditis
Ischemic Stroke
Intracerebral Hemorrhage
CNS Infections
Conclusions
Chapter 12: Neurologic complications of nonbacterial thrombotic endocarditis
Abstract
Introduction
Epidemiology
Pathogenesis
Clinical Symptomatology
Diagnosis
Differential Diagnosis
Management
Prognosis
Conclusion
Chapter 13: Neurologic complications of atrial fibrillation: Pharmacologic and interventional approaches to stroke prevention
Abstract
Introduction
Risk Stratification
Pharmacologic Therapies
Nonpharmacologic Therapies or Left Atrial Appendage Closure
Conclusion
Chapter 14: Tachyarrhythmias and neurologic complications
Abstract
Atrioventricular Electrophysiology and the Autonomic System
Types of Tachyarrhythmia
Atrial Tachycardia
AVNRT and AVRT
Ventricular Tachycardia
Ventricular Fibrillation and Flutter
Torsade De Pointes
Conclusion
Chapter 15: Neurologic complications of brady-arrhythmias
Abstract
Neurologic Complications of Brady-Arrhythmias
Background Physiology
Neurologic Complications
Chapter 16: Effects of acute neurologic disease on the heart
Abstract
Introduction
Normal Physiology
Brain
Spinal Cord
Peripheral Nerve
Neuromuscular Junction
Conclusion
Chapter 17: Neurologic complications of genetic channelopathies
Abstract
Long QT Syndrome and Deafness
Andersen-Tawil Syndrome (ATS)
Timothy Syndrome
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) and Seizures
Brugada Syndrome and Seizures
Sinoatrial Node Dysfunction and Deafness
Conclusion
Chapter 18: Neurological complications of syncope and sudden cardiac arrest
Abstract
Mechanism of Syncope
Cardiac Arrhythmia With Cerebral Hypoperfusion
Sudden Cardiac Death With Possible Neurological Interaction
Summary
Chapter 19: Neurologic complications of cardiac arrest
Abstract
Introduction
Pathophysiology of Brain Injury in Cardiac Arrest
Interventions
Prognostication of Neurologic Outcome
Conclusion
Chapter 20: Neurologic complications of implantable devices
Abstract
Heart Valve Replacement
Implanted Devices for Secondary Stroke Prevention
Implantable Mechanical Circulatory Support Devices
Chapter 21: Neurologic complications of diseases of the aorta
Abstract
Introduction
Spinal Cord Vascular Supply
Neurologic Complications of Aortic Disease
Neurologic Complications of Aortic Surgery
Conclusion
Chapter 22: Cerebral aneurysms and cervical artery dissection: Neurological complications and genetic associations
Abstract
Introduction
Neurologic Complications of Intracranial Aneurysms
Neurologic Complications of Cervical Artery Dissection
Monogenic Syndromes Associated with Aneurysms and Dissection
Polygenic Associations of Aneurysms and Dissection
Conclusion/Summary
Chapter 23: Neurological complications of systemic hypertension
Abstract
Introduction and Background
Hypertensive Encephalopathy
Stroke
Intracranial Atherosclerosis and Hypertrophic Remodeling
Cognitive Impairment and Dementia
Chapter 24: Neurologic complications of venous thromboembolism
Abstract
Introduction
Risk of Ischemic Cerebrovascular Disease After VTE
Intracranial Hemorrhage Following VTE
VTE as the Initial Manifestation of Brain Tumors
Peripheral Nervous System Complications of VTE
Conclusions
Chapter 25: Neurologic complications of cardiac disease in athletes
Abstract
Introduction
Athlete's Heart
Cardiac Rhythm Changes Among Athletes
Neurological Manifestation of Cardiac Disease Among Athletes
Summary
Chapter 26: Cerebrovascular manifestations of tumors of the heart
Abstract
Introduction
General Clinical Presentations of Cardiac Tumors
Other Primary Tumors
Metastatic Heart Tumors
Conclusions
Chapter 27: Stroke in pregnancy
Abstract
Epidemiology
Etiology
Management
Chapter 28: Hemodynamics in acute stroke: Cerebral and cardiac complications
Abstract
Introduction
Hemodynamic Changes in Acute Ischemic Stroke
Implications of Hemodynamics for Selecting Patients for Revascularization Procedures
Enhancing Hemodynamics in Acute Stroke
Conclusion
Chapter 29: Neurological complications of cardiovascular drugs
Abstract
Introduction
Antihypertensive Drugs
Diuretics
Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers
Calcium Channel Blockers
Alpha 1-Adrenergic Receptor Blockers
Beta-Adrenergic Blockers
Vasodilators
Cholesterol-Lowering Drugs
Statins
Cholesterol Absorption Inhibitor, Ezetimibe
Fibric Acid Derivatives
PCSK9 Inhibitors
Antiarrhythmic Drugs
Antiplatelet Drugs
Aspirin
P2Y12 Receptor Inhibitors
Glycoprotein IIb/IIIa Inhibitors
Anticoagulant Drugs
Vitamin K Antagonists, Warfarin
Direct Oral Anticoagulants
Heparin, Enoxaparin, and Fondaparinux
Parenteral Thrombin Inhibitors
Fibrinolytics
Heart Failure Drugs
Antianginal Drugs
Future Directions
Chapter 30: The role of biomarkers and neuroimaging in ischemic/hemorrhagic risk assessment for cardiovascular/cerebrovascular disease prevention
Abstract
Introduction
Stratification of Embolic Stroke Risk in AF
Stratification of Hemorrhagic Stroke Risk in AF
Prevention of Ischemic Stroke in Patients With AF at Low Hemorrhagic Risk
Prevention of Ischemic and Hemorrhagic Strokes/Events in Patients With AF at High Hemorrhagic Risk
Risk Stratification Methods and Antiplatelet Use
Conclusions
Study support
Chapter 31: Clinical utility of echocardiography in secondary ischemic stroke prevention
Abstract
Introduction
Therapeutic Relevance of Echocardiographic Findings in Acute Cerebral Ischemia
TTE vs TTE for Detection of Therapeutically Relevant Cardiac Pathologies
Clinical Correlations and Associations With Therapeutically Important Cardiac Pathologies
Cost-Effectiveness Studies
Summary and Conclusions
Chapter 32: The relationship between heart disease and cognitive impairment
Abstract
Introduction
Coronary Heart Disease
Congestive Heart Failure and Low Output States
Atrial Fibrillation
Atrial Cardiomyopathy
Cardiovascular Risk Factors and Cognitive Impairment
Links Between Vascular Risk Factors and Neurodegeneration
Interventional Trials
Conclusions
Chapter 33: Anxiety and psychological management of heart disease and heart surgery
Abstract
Introduction
Overview of Anxiety and Heart Disease
Anxiety and Vascular Risk Factors
Physiology of Anxiety
Neurologic Manifestations of Anxiety and Heart Disease
Assessment and Diagnosis of Anxiety
Prevention and Treatment of Anxiety Disorders
Prevention and Treatment
Conclusions
Index

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Jose Biller